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Asymptotic Expansion of Temperature Close to a Singularity of a Plate  [PDF]
Isabelle Titeux
World Journal of Mechanics (WJM) , 2011, DOI: 10.4236/wjm.2011.13015
Abstract: The thermal conduction in a thin laminated plate is considered here. The lateral surface of the plate is not regular. Consequently, the boundary of the middle plane admits a geometrical singularity. Close to the origin, the lateral edge forms an angle. We shall prove that the classical bidimensional problem associated with the thin plate problem is not valid. In this paper, using the boundary layer theory, we describe the local behavior of the plate, close to the perturbation.
Peri-Orbital Non-Invasive and Painless Skin Tightening-Safe and Highly Effective Use of Multisource Radio-Frequency Treatment Platform  [PDF]
Isabelle Rousseaux
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2015, DOI: 10.4236/jcdsa.2015.53025
Abstract: The periorbital area is the third highest-ranking area for cosmetic surgery. However, surgery in this area presents a number of difficulties and safety concerns. First generation Monopolar RF treatments in this area were usually associated with considerable pain and long downtime. In the present clinical study, we used the iFine handpiece of the EndyMed PRO, multi-source phase-controlled radiofrequency (RF) for Non-invasive, pain free, skin rejuvenation of the periorbital area. The study included eleven (11) subjects, treated for periorbital signs of aging (iFine handpiece, EndyMed PRO platform, EndyMed Medical, Caesarea, Israel). The degree of clinical improvement was assessed by the global aesthetic improvement scale (GAIS) and subjects satisfaction by post treatment questionnaires. 91% of patients showed good to excellent improvement as a result of the treatment. Subjects satisfaction showed that 55% of patients reported that they were very satisfied, 45% were satisfied while none were dissatisfied. There were no incidences of infections, scarring, hypopigmentation, or any other serious complications.
Carotid Endothelial VCAM-1 Is an Early Marker of Carotid Atherosclerosis and Predicts Coronary Artery Disease in Swine  [PDF]
Isabelle Masseau, Douglas K. Bowles
Journal of Biomedical Science and Engineering (JBiSE) , 2015, DOI: 10.4236/jbise.2015.811073
Abstract: Objective: The aim was to determine if endothelial VCAM-1 (eVCAM-1) expression in the common carotid artery (CCA) would correlate with predictive markers of atherosclerotic disease, would precede reduction of markers of endothelial cell function and would predict coronary artery disease (CAD). Methods and results: Carotid arterial segments (bifurcation, proximal and distal CCA) were harvested from 14 and 24 month-old male castrated familial hypercholesterolemic (FH) swine, a model of spontaneous atherosclerosis. Quantification of local expression of eVCAM-1, intimal macrophage accumulation, oxidative stress, intima-media (I/M) ratio, intima-media thickness (IMT), endothelial nitric oxide synthase (eNOS) and phosphorylated eNOS (p-eNOS) in selected regions of the carotids revealed a relationship between local inflammation and atherosclerotic plaque progression. Importantly, inflammation was not uniform throughout the CCA. Endothelial VCAM-1 expression was the greatest at the bifurcation and increased with age. Finally, eVCAM-1 best estimated the severity of CAD compared to blood levels of glucose, hypercholesterolemia, carotid IMT, and p-eNOS. Conclusion: Our data suggested that eVCAM-1 was closely associated with atherosclerotic plaque progression and preceded impairment of EDD. Thus, this study supported the use of carotid VCAM-1 targeting agents to estimate the severity of CAD.
Mycobacterium avium Paratuberculosis (MAP) and Cytomegalovirus (CMV) Are Frequently Detected in the Saliva of Patients Recently Diagnosed with Crohn Disease (CD) Whereas Oral Propionibacterium Acnes (PA) or Methylacetate (MA) in Their Breath Is Rare  [PDF]
Donatini Bruno, Le Blaye Isabelle
Journal of Biosciences and Medicines (JBM) , 2015, DOI: 10.4236/jbm.2015.312003

We investigated the presence of MAP, CMV, or Epstein-Barr virus (EBV) in the saliva of patients presenting with periodontal disease, gingivitis or oral aphthosis. We also measured methylacetate in their breath and looked for the presence of PA on their tongue. All patients were prospectively enrolled into a two-year cohort study. We compared the group presenting with CD versus the group without CD. 167 patients were enrolled. 24 patients presented with CD. CMV and MAP were found concomitantly in 67% of CD patients (17 patients) whereas only 1 patient (<0.1%; p < 0.001) has these infectious agents in the comparative group. PA was rare in CD (25% versus 70.6%; p < 0.001). MA was low, especially with an empty stomach (0.59 ppm +/? 1.45 versus 5.14 ppm +/? 8.97; p < 0.001). It was concluded that the association MAP + CMV was frequently found in oral lesions of CD at an early stage. Detection of PA, MAP and CMV, as well as breath test could be easily performed and may participate to the early diagnosis of CD.

O paradoxal estatuto do conhecimento jornalístico: entre a desconsidera??o e o protagonismo do saber produzido pelas notícias nas sociedades modernas
Anchieta, Isabelle;
Intercom: Revista Brasileira de Ciências da Comunica??o , 2011, DOI: 10.1590/S1809-58442011000200009
Abstract: the knowledge of journalism debate produces a paradox: on the one hand, it is the most appropriate way to meet the present and historical events in modern societies, on the other hand, is considered insufficient knowledge, fragmented and ideologically committed to the social reality . in this article we ask: which is, after all the place of knowledge generated for journalism in modern society? let's get into the discussion in the context of the crisis of traditional knowledge and science as truth. its effects reach particularly the form of journalism and creates a dilemma: whether journalism can not be legitimized in scientific terms would then be closer to the knowledge based on common sense? for that, compared two theoretical perspectives on knowledge news: the german tobias peucer, seventeenth century, and the american robert park, of the twentieth century. in this comparison we are interested in observing the changes, but especially that which remains in journalistic practices to finally establish the ethics of journalistic knowledge.
From street to job: integrating juvenile delinquents
Etnográfica , 2010,
Abstract: since the 1970s, given the transformations of the job market and the changes in ?street culture?, professional morals replace ?street morals? less easily than before, and the shop floor is less integrative for juvenile delinquents. in that sense, the importance of the role played by the institutions involved in the process of normalization has grown in proportion. by studying an integration system for juvenile delinquents, in a french banlieue, it is precisely that sort of ambition i wished to apprehend. through the case studies of three young men, i explain the reasons why the young people involved in the system participate in it, and the conditions that need to be met for a street educator?s moral authority to be acknowledged. i underscore the acculturation that takes place at the heart of the system and the type of competences that can be acquired there. i show also, the stigmata linked to a delinquent past can always get in the way of the process and reactivate habits developed in the ?street?.
Uso de los datos de plumbemia para evaluar y prevenir el envenenamiento infantil por plomo en Latinoamérica
Salud Pública de México , 2003, DOI: 10.1590/S0036-36342003000800012
Abstract: exposure to lead is a widespread and serious threat to the health of children in latin america. health officials should monitor sources of exposure and health outcomes to design, implement, and evaluate prevention and control activities. to evaluate the magnitude of lead as a public health problem, three key elements must be defined: 1) the potential sources of exposure, 2) the indicators to evaluate health effects and environmental exposure, and 3) the sampling methods for the population at risk. several strategies can be used to select the study population depending on the study objectives, the time limitations, and the available resources. if the objective is to evaluate the magnitude and sources of the problem, the following sampling methods can be used: 1) population-based random sampling; 2) facility-based random sampling within hospitals, daycare centers, or schools; 3) target sampling of high risk groups; 4) convenience sampling of volunteers; and 5) case reporting (which can lead to the identification of populations at risk and sources of exposures). for all sampling methods, information gathering should include the use of a questionnaire to collect general information on the participants and on potential local sources of exposure, as well as the collection of biological samples. in interpreting data, one should consider the type of sampling used and the non-response rates, as well as factors that might influence blood lead measurements, such as age and seasonal variability. blood lead measurements should be integrated in an overall strategy to prevent lead toxicity in children.
Diet and breast cancer
Salud Pública de México , 2011, DOI: 10.1590/S0036-36342011000500011
Abstract: both diet and nutrition have been studied in relationship with breast cancer risk, as the great variation among different countries in breast cancer incidence could possibly be explained through the inflammatory and immune response, as well as antioxidant intake, among others.to date, no clear association with diet beyond overweight and weight gain has been found, except for alcohol consumption. nonetheless, the small number of studies done in middle to low income countries where variability of food intake is wider,is beginning to show interesting results.
Participation of the Public in Science: Towards a New Kind of Scientific Practice
Isabelle Peschard
Human Affairs , 2007, DOI: 10.2478/v10023-007-0013-x
Abstract: Participation of the public in science has been the object of an increasing number of social and political philosophical studies, but there is still hardly any epistemological study of the topic. While it has been objected that involvement of the public is a threat to the integrity of science, the apparent indifference of philosophers of science seems to testify to its lack of relevance to conceptions of scientific activity. I argue both that it is not a threat to science and that it is relevant to philosophy of science by showing that it constitutes a new kind of epistemic practice. Two main objections to the idea that the involvement of non-scientists, with their situated perspective and contextual values, can form an epistemic practice will be addressed: the first bears on the epistemic potentialities of the cooperation between scientist and non-scientists; the second on the possibility that this cooperation takes the form of a practice.
Uso de los datos de plumbemia para evaluar y prevenir el envenenamiento infantil por plomo en Latinoamérica
Romieu Isabelle
Salud Pública de México , 2003,
Abstract: La exposición al plomo es una amenaza seria para la salud de los ni os, que se encuentra ampliamente distribuida en la Región de América Latina. Los funcionarios de salud pública necesitan identificar fuentes de exposición al plomo, así como sus efectos en la salud, para poder dise ar, implantar y evaluar las actividades preventivas y de control. Para evaluar la magnitud del problema del plomo es necesario definir tres elementos clave: a) las fuentes potenciales de exposición, b) los indicadores que se utilizarán para evaluar los efectos en la salud y la exposición en el medio ambiente, y c) las estrategias de muestreo de la población en riesgo. Se pueden utilizar varias estrategias con el fin de seleccionar la población blanco dependiendo de los objetivos del estudio, el tiempo límite y los recursos disponibles. Si el objetivo es evaluar la magnitud y las fuentes del problema pueden emplearse los siguientes métodos de muestreo: a) el muestreo al azar basado en la población; b) el muestreo al azar basado en las facilidades dentro de los hospitales, las guarderías o las escuelas; c) el muestreo objetivo de los grupos de alto riesgo; d) el muestreo de conveniencia (de voluntarios), y e) el reporte de los casos (éste puede conducir a la identificación de las poblaciones en riesgo, además de las fuentes de exposición). Para todos los dise os de muestreo, la información debe incluir tanto el uso de un cuestionario para el informe general de los participantes y de las fuentes potenciales locales de exposición, como la recolección de las muestras biológicas. En la interpretación de los datos se debe considerar el tipo de muestreo utilizado, el porcentaje de falta de respuesta y los factores que pueden influir en las mediciones del plomo en sangre, como la edad y la variación de la temporada. Las mediciones del plomo en la sangre se deben integrar dentro de una estrategia general para la prevención de toxicidad.
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