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Search Results: 1 - 10 of 29894 matches for " Hyuk Jin Cho "
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Induced Spin from the $ISO(2,1)$ Gauge Theory with the Gravitational Chern-Simons Term
Jin-Ho Cho,Hyuk-jae Lee
Physics , 1995, DOI: 10.1016/0370-2693(95)00360-W
Abstract: In the context of $ISO(2,1)$ gauge theory, we consider $(2+1)$-dimensional gravity with the gravitational Chern-Simons term (CST). This formulation allows the `exact' solution for the system coupled to a massive point particle (which is not the case in the conventional Chern-Simons gravity). The solution exhibits locally trivial structure even with the CST, although still shows globally nontrivialness such as the conical space and the helical time structure. Since the solution is exact, we can say the CST induces spin even for noncritical case of $\s+\al m\ne 0$.
Is the $ISO(2,1)$ Gauge Gravity equivalent to the Metric Formulation?
Jin-Ho Cho,Hyuk-jae Lee
Physics , 1996,
Abstract: The quantization of the gravitational Chern-Simons coefficient is investigated in the framework of $ISO(2,1)$ gauge gravity. Some paradoxes involved are cured. The resolution is largely based on the inequivalence of $ISO(2,1)$ gauge gravity and the metric formulation. Both the Lorentzian scheme and the Euclidean scheme lead to the coefficient quantization, which means that the induced spin is not quite exotic in this context.
Polyakov's Spin Factor for a Classical Spinning Particle via BRST Invariant Path Integral
Jin-Ho Cho,Seungjoon Hyun,Hyuk-Jae Lee
Physics , 1994, DOI: 10.1016/0370-2693(94)90728-5
Abstract: For the `classical' formulation of a massive spinning particle, the propagator is obtained along with the spin factor. We treat the system with two kinds of constraints that were recently shown to be concerned with the reparametrization invariance and `quasi-supersymmetry'. In the path integral, the BRST invariant Lagrangian is used and the same spin factor is obtained as in the pseudo-classical formulation.
Is It Effective to Perform Two More Prostate Biopsies According to Prostate-Specific Antigen Level and Prostate Volume in Detecting Prostate Cancer? Prospective Study of 10-Core and 12-Core Prostate Biopsy
Byung Il Yoon,Tae Seung Shin,Hyuk Jin Cho,Sung-Hoo Hong
Urology Journal , 2012,
Abstract: PURPOSE: To evaluate the effectiveness of 2 more core prostate biopsy protocol in detecting the prostate cancer (PCa) by comparing 10-core prostate biopsy with 12-core according to the prostate-specific antigen (PSA) level and the prostate volume. MATERIALS AND METHODS: A total of 474 men with elevated serum levels of PSA between 2.5 and 20.0 ng/mL, regardless of abnormal finding on digital rectal examination and transrectal ultrasonography, received transrectal ultrasound-guided prostate biopsies. The patients were prospectively randomized to undergo 10-core (group 1, n = 351) or 12-core (group 2, n = 123) biopsy. The PCa detection rates were assessed and compared according to the serum level of PSA and prostate volume. RESULTS: Of 474 men, 128 (27.0%) were diagnosed with PCa. The PCa detection rates of 10-core and 12-core biopsies were 26.4% and 28.4%, respectively (P = .378). There was no difference in cancer detection rates according to PSA level in both groups. Comparing the cancer detection rates according to the prostate volume (< 40 mL and ≥ 40 mL), the patients with prostate volume ≥ 40 mL showed higher cancer detection rates in 12-core biopsy group (26.9%) compared with 10-core biopsy group (16.4%) (P < .05). CONCLUSION: The overall cancer detection rates showed no differences in both groups. But the 12-core biopsy was a more efficient method in men with a prostate volume of ≥ 40 mL, compared to the 10-core biopsy.
Bacterial Heavy Metal Resistance Genes and Bioremediation Potential  [PDF]
Hannah Johnson, Hyuk Cho, Madhusudan Choudhary
Computational Molecular Bioscience (CMB) , 2019, DOI: 10.4236/cmb.2019.91001
Abstract: There is a worldwide distribution of heavy metal pollution that can be managed with a bioremediation approach using microorganisms. Several bacterial species belonging to the Proteobacteria have been shown to tolerate heavy metal stress, including toxic salts of noblemetals. Rhodobacter sphaeroides, a model bacterium has previously been utilized for bioremediation studies. A bioinformatics approach was employed here to identify the distribution of genes associated with heavy metal tolerance among the sequenced bacterial genomes currently available on the NCBI database. The distribution of these genes among different groups of bacteria and the Cluster of Orthologous Groups (COGs) were further characterized. A total of 170,000 heavy metal related genes were identified across all bacterial species, with a majority of the genes found in Proteobacteria (46%) and Terrabacteria (39%). Analysis of COGs revealed that the majority of heavy metal related genes belong to metabolism (COG 3), including ionic transport, amino acid biosynthesis, and energy production.
The analytic continuation of hyperbolic space
Yunhi Cho,Hyuk Kim
Mathematics , 2006,
Abstract: We define and study an extended hyperbolic space which contains the hyperbolic space and de Sitter space as subspaces and which is obtained as an analytic continuation of the hyperbolic space. The construction of the extended space gives rise to a complex valued geometry consistent with both the hyperbolic and de Sitter space. Such a construction shed a light and inspires a new insight for the study of the hyperbolic geometry and Lorentzian geometry. We discuss the advantages of this new geometric model as well as some of its applications.
Volume of $C^{1,α}$-boundary domain in extended hyperbolic space
Yunhi Cho,Hyuk Kim
Mathematics , 2006,
Abstract: We consider the projectivization of Minkowski space with the analytic continuation of the hyperbolic metric and call this an extended hyperbolic space. We can measure the volume of a domain lying across the boundary of the hyperbolic space using an analytic continuation argument. In this paper we show this method can be further generalized to find the volume of a domain with smooth boundary with suitable regularity in dimension 2 and 3. We also discuss that this volume is invariant under the group of hyperbolic isometries and that this regularity condition is sharp.
Hormonal responses upon return of spontaneous circulation after cardiac arrest: a retrospective cohort study
Jin Joo Kim, Sung Youl Hyun, Seong Youn Hwang, Young Bo Jung, Jong Hwan Shin, Yong Su Lim, Jin Seong Cho, Hyuk Jun Yang, Gun Lee
Critical Care , 2011, DOI: 10.1186/cc10019
Abstract: This is a retrospective review of the chart and laboratory findings in a single medical facility. The patients admitted to the intensive care unit after successful resuscitation after out-of-hospital cardiac arrest were retrospectively identified and evaluated. Patients with hormonal diseases, patients who received cortisol treatment, those experiencing trauma, and pregnant women were excluded. Serum cortisol, adrenocorticotropic hormone (ACTH), and anti-diuretic hormone (ADH (vasopressin)) were analyzed and a corticotropin-stimulation test was performed. Mortality at one week and one month after admission, and neurologic outcome (cerebral performance category (CPC)) one month after admission were evaluated.A total of 117 patients, including 84 males (71.8%), were evaluated in this study. One week and one month after admission, 87 (74.4%) and 65 patients (55.6%) survived, respectively. Relative adrenal insufficiency, and higher plasma ACTH and ADH levels were associated with shock-related mortality (P = 0.046, 0.005, and 0.037, respectively), and ACTH and ADH levels were also associated with late mortality (P = 0.002 and 0.004, respectively). Patients with relative adrenal insufficiency, ACTH ≧5 pg/mL, and ADH ≧30 pg/mL, had a two-fold increased risk of a poor outcome (shock-related mortality): (odds ratio (OR), 2.601 and 95% confidence interval (CI), 1.015 to 6.664; OR, 2.759 and 95% CI, 1.060 to 7.185; OR, 2.576 and 95% CI, 1.051 to 6.313, respectively). Thirty-five patients (29.9%) had a good CPC (1 to 2), and 82 patients (70.1%) had a bad CPC (3 to 5). Age ≧50 years and an ADH ≧30 pg/mL were associated with a bad CPC (OR, 4.564 and 95% CI, 1.794 to 11.612; OR, 6.568 and 95% CI, 1.918 to 22.483, respectively).The patients with relative adrenal insufficiency and higher blood levels of ACTH and ADH upon ROSC after cardiac arrest had a poor outcome. The effectiveness of administration of cortisol and ADH to patients upon ROSC after cardiac arrest is uncertain and ad
Comparison of Estimating Equations for the Prediction of Glomerular Filtration Rate in Kidney Donors before and after Kidney Donation
Byung Ha Chung, Jee Hyun Yu, Hyuk Jin Cho, Ji-Il Kim, In Sung Moon, Cheol Whee Park, Chul Woo Yang, Yong-Soo Kim, Bum Soon Choi
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0060720
Abstract: The aim of this study is to investigate the usefulness of the GFR-estimating equations to predict renal function in kidney donors before and after transplantation. We compared the performance of 24-hour-urine–based creatinine clearance (24 hr urine-CrCl), the Cockcroft-Gault formula (eGFRCG), the Modification of Diet in Renal Disease equation (eGFRMDRD), and the Chronic Kidney Disease Epidemiology Collaboration equation (eGFRCKD-EPI) with technetium-diethylenetriaminepentaacetic acid (99mTc-DTPA) clearance (mGFR) in 207 potential kidney donors and 108 uninephric donors. Before donation, eGFRCKD-EPI showed minimal bias and did not show a significant difference from mGFR (P = 0.65, respectively) while 24 hr urine-CrCl and eGFRMDRD significantly underestimated mGFR (P<0.001 for each). Precision and accuracy was highest in eGFRCKD-EPI and this better performance was more dominant when renal function is higher than 90 mL·min?1·1.73 m?2. After kidney donation, eGFRMDRD was superior to other equations in precision and accuracy in contrast to before donation. Within individual analysis, eGFRMDRD showed better performance at post-donation compared to pre-donation, but eGFRCKD-EPI and eGFRCG showed inferior performance at post-donation. In conclusion, eGFRCKD-EPI showed better performance compared to other equations before donation. In a uninephric donor, however, eGFRMDRD is more appropriate for the estimation of renal function than eGFRCKD-EPI.
The Effect of Soluble RAGE on Inhibition of Angiotensin II-Mediated Atherosclerosis in Apolipoprotein E Deficient Mice
Dajeong Lee, Kyung Hye Lee, Hyelim Park, Soo Hyuk Kim, Taewon Jin, Soyoung Cho, Ji Hyung Chung, Soyeon Lim, Sungha Park
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0069669
Abstract: Background The cross talk between RAGE and angiotensin II (AngII) activation may be important in the development of atherosclerosis. Soluble RAGE (sRAGE), a truncated soluble form of the receptor, acts as a decoy and prevents the inflammatory response mediated by RAGE activation. In this study, we sought to determine the effect of sRAGE in inhibiting AngII-induced atherosclerosis in apolipoprotein E knockout mice (Apo E KO). Methods and Results 9 week old Apo E KO mice were infused subcutaneously with AngII (1 μg/min/kg) and saline for 4 weeks using osmotic mini-pumps. The mice were divided into 4 groups 1. saline infusion and saline injection; 2. saline infusion and sRAGE injection; 3. AngII infusion and saline injection; 4. AngII infusion and sRAGE injection. Saline or 0.5 μg, 1 μg, to 2 μg/day/mouse of sRAGE were injected intraperitoneally daily for 28 days. We showed that atherosclerotic plaque areas in the AngII-infused Apo E KO mice and markers of inflammation such as RAGE, ICAM-1, VCAM-1, and MCP-1 were increased in aorta compared to that of the Apo E KO mice. However, the treatment of 0.5 μg, 1 μg, and 2 μg of sRAGE in AngII group resulted in the dose-dependent decrease in atherosclerotic plaque area. We also demonstrated that sRAGE decreased RAGE expression level as well as inflammatory cytokines and cell adhesion molecules in AngII or HMGB1 treated-rat aorta vascular smooth muscle cells. Conclusion The results demonstrated that partical blockade of RAGE activation by sRAGE prevent AngII -induced atherosclerosis. Therefore these results suggested that first, RAGE activation may be important in mediating AngII-induced atherogenesis, and second, AngII activation is a major pathway in the development of atherosclerosis. Taken together, results from this study may provide the basis for future anti- atherosclerotic drug development mediated through RAGE activation.
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