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Study and Characterization of Expansive Cement Estudio y caracterización de cementos expansivos
Hugo Guerra Menéndez,Eduardo Peón Avés,Julio E. Lanza Rodríguez
Revista Cubana de Ingeniería , 2011, DOI: 10.1234/rci.v2i3.58
Abstract: The objective of this study is to characterize commercial expansive cement for subsequent development of national formulation, with consequent economic effect and independence of the international market. On the other hand the results contribute to the development of scientific and technological potential. Expansive cement is a product that enables non-explosive demolition, rock and concrete demolition. To characterize the composition of these products, techniques used infrared spectroscopy with Fourier Transforms and Scanning Electron Microscopy. El objetivo del trabajo consiste en caracterizar un cemento expansivo comercial, para el posterior desarrollo de una formulación nacional, con el consecuente efecto económico y de independencia del mercado internacional. Por otra parte, los resultados contribuyen al desarrollo del potencial científicotecnológico. El cemento expansivo es un producto demoledor no explosivo que permite demoler rocas y hormigones. Para caracterizar la composición de estos productos, se emplean las técnicas de espectroscopia infrarroja con transformada de Fourier y microscopía electrónica de barrido. Se determina que estos cementos están compuestos por óxidos, silicatos, sulfato, ferritoaluminato y aluminato de calcio.
Actividad antimicrobiana y toxicidad de un extracto acuoso de Boerhaavia erecta L
Marta Guerra Ordo?ez,Raiza Vega Montalvo,Reinaldo Rivero Martínez,Rosa Menéndez Castillo
Revista Cubana de Plantas Medicinales , 2004,
Abstract: Se evaluó la actividad antimicrobiana in vitro y la toxicidad aguda oral de un extracto acuoso de Boerhaavia erecta, L. Se empleó el ensayo de diluciones en medio líquido y se determinó la concentración mínima inhibitoria y mínima microbicida frente a microorganismos de interés clínico humano. La toxicidad fue evaluada mediante el ensayo de dosis límite. Similar a otras especies del género, el extracto mostró actividad antifúngica frente a Microsporum canis. No se encontró mortalidad a la dosis de ensayo empleada por lo que el extracto fue considerado no tóxico. The in vitro antimicrobial activity and the acute oral toxicity of an aqueous extract of Boerhaavia erecta L. were evaluated. The assay of dilutions in liquid medium was used, and the minimum inhibitory and the minimum microbicidal concentration against microorganisms of human clinical interest were determined. Toxicity was evaluated by the limited dose test according to the norm of OECD. Like other species of the genus, the extract showed antifungal activity against Microsporum canis. As the dose used in the assay caused no mortality, the extract was considered as non toxic.
In Vitro Genotoxic Potential of D-003 on the Blood Lymphocytes Chromosomal Aberration Test
Rafael Gámez Menéndez,Ariadne Gutiérrez Martínez,Rosa Mas Ferreiro,Balia Pardo Guerra
RETEL : Revista de Toxicología en Línea , 2012,
Abstract: Background: D-003, a mixture of very high molecular weight aliphatic acids purified from sugarcane wax, has been shown antioxidant, lipid-modifying and antiosteoporotic properties in preclinical and clinical studies. Objective: This study investigated the in vitro genotoxic potential of D-003 to produce chromosomal aberrations (CA) in peripheral blood lymphocytes.Methods: Fresh suspensions of D-003 were added (1 000, 2 500 and 5 000 g/mL) to cultures with (microsomal liver fraction S9 mix) or without metabolic activation. Concurrent negative (Tween/water vehicle) and positive controls (cyclophosphamide 15 g/mL and mitomicyn-C 0.3 g/mL in the tests with and without metabolic activation, respectively) were included. Two hundred (200) metaphases by group were examined and the numbers and frequencies of cells with aberrations and the mitotic index were quantified. Results: D-003 added up to 5 000μg/mL of culture did not induce chromosomal aberrations in presence or not of S9 mix compared with negative controls and no trends with the doses were observed. Positive controls evidenced increases of the numbers and frequencies of CA. Mitotic indexes were unchanged with the treatment, which indicates that D-003 does not affect cell proliferation. Conclusions: D-003 added in vitro (1 000-5 000 -μg/mL) to peripheral blood lymphocyte cultures did not show evidences of cytotoxic or genotoxic potential in the CA test.
Zinc plasmático, cobre sérico y zinc y cobre eritrocitarios en adultos sanos de Buenos Aires Plasmatic zinc, serum copper and erythrocyte zinc and copper levels in healthy adult people living in Buenos Aires
Adriana Ruth Weisstaub,Ana María Menéndez,Hugo Montemerlo,Horacio Pastene
Acta bioqu?-mica cl?-nica latinoamericana , 2008,
Abstract: Se estudiaron adultos, clínicamente sanos, 21 varones (V) y 19 mujeres (M), de: edad (a os): V: 48±14 (28-78); M: 41±14 (23-66); índice de masa corporal (kg/m2): V: 26,7±2,3 (23,1-31,9); M: 22,2±3,5 (19,3-29,6). Se realizó una encuesta nutricional y se extrajo sangre en ayunas. Se realizaron las determinaciones de rutina del laboratorio clínico. Se determinó zinc en plasma (ZnPl), cobre en suero (CuS); en eritrocitos: Zinc (ZnGR) y cobre (CuGR), por espectrometría de absorción atómica. La totalidad de los V y M presentaron ingestas adecuadas de energía, proteínas, Zn y Cu. Los resultados expresados como: promedio ± desvío estándar y rangos fueron: ZnPl (μg/dL): V: 93±27 (49-161); M: 79±28 (42-157); ZnGR (μg/dL): V: 1.380±210 (1.110-2.010); M: 1.350±130 (1.090-1.520); CuS (μg/dL): V: 89±20 (40- 122); M: 93±28 (45-157). CuGR (μg/dL): V: 59±12 (37-78); M: 63±19 (30- 110). No se evidenciaron diferencias significativas entre V y M. Los resultados para la población estudiada fueron, percentilos 5 y 95, respectivamente: ZnPl: 49 a 131 μg/dL; ZnGR: 1.130 a 1.610 μg/dL; Zn/Hb: 34,4 a 47,5 μg/g; CuS: 45 a 124 μg/dL; CuGR: 36 a 78 μg/dL. Los valores de ZnPl y CuS se encuadraron dentro de los rangos de valores de referencia internacionales, sin diferencias significativas de acuerdo con el género. Two groups of adult healthy people were studied: 21 males (M) and 19 females (F). Mean age (ys) was: M: 48±14 (28-78); F: 41±14 (23-66); body mass index (Kg/m2) was: M: 26.7±2.3 (23.1-31.9); F: 22.2±3.5 (19.3-29.6). A nutritional survey was recorded and mean daily intake of energy, protein, Zinc (Zn) and Copper (Cu) were calculated. Fasting blood samples were obtained in order to determine Hemoglobin (Hb), plasmatic Zn (PlZn), serum Cu (SCu), erythrocyte Zn (EZn) and erythrocyte Cu (ECu) levels. Zn and Cu were determined by AAS. Results were: mean±SD and ranges: PlZn (μg/dL): M: 93±27 (49-161); F: 79±28 (42-157); EZn (μg/dL): M: 1380±210 (1110-2010); F: 1350±130 (1090-1520); SCu (μg/dL): M: 89±20 (40-122); F: 93±28 (45-157). ECu (μg/dL): M: 59±12 (37-78); F: 63±19 (30-110). All individuals presented adequate intake of energy, protein, Zn and Cu. There were no significant differences between M and F for PlZn, EZn, Zn/Hb ratio, SCu and ECu. The results for the adult healthy population in Argentina, and which were in accordance with the international published values were: (percentiles 5 y 95, respectively): PlZn: 49 - 131 μg/dL; EZn: 1130 - 1610 μg/dL; Zn/Hb: 34,4 - 47,5 μg/g; SCu: 45 - 124 μg/dL; ECu: 36 - 78 μg/dL.
Estudio de la inducción de letales dominantes del D-002 en ratones NMRI de los dos sexos
Idania Rodeiro Guerra,Rafael Gámez Menéndez,Ivonne Fernández Rodríguez,Rosa Más Ferreiro
Revista Cubana de Investigaciones Biom??dicas , 1999,
Abstract:
Acción analgésica de la digitopuntura previa al tratamiento estomatológico convencional en las pulpitis agudas
Betancourt Gamboa,Kenia; Barciela Calderón,Julio; Guerra Menéndez,Julio; Alberti Vázquez,Lissette; Rodríguez Ramos,Sonia;
Revista Archivo M??dico de Camag??ey , 2011,
Abstract: background: patients with acute pulpitis caused to the pain that characterizes it, in occasions allow carrying out a satisfactory endodontic treatment of urgency. objective: to evaluate the analgesic action of digitopuncture previous to the conventional stomatological treatment in acute pulpitis. method: a before and after type quasi-experimental, evaluation study was performed, in the stomatological urgency consultation at previsora polyclinic from september 2008 to april 2009, the study universe was conformed by patients that came to the consultation with pain caused by acute pulpitis and the sample was integrated by 40 patients who had not received previous treatment. the intensity of pain was evaluated to 30 minutes and patient's cooperation was valued during the conventional treatment. results: in 90% of cases was evaluated as effective the treatment carried out and patients referred to feel satisfied with the treatment received (90%). conclusions: the intensity of pain before treatment was moderate in more than the half of patients and the ? parts of the sample referred having no pain.
Aplicación de la ozonoterapia en el tratamiento de la alveolitis
CRUZ GUERRA,OLGA; MENéNDEZ CEPERO,SILVIA; MARTíNEZ JORDáN,MARíA E.; CLAVERA VáZQUEZ,. TERESITA;
Revista Cubana de Estomatolog?-a , 1997,
Abstract: the etiology of alveolitis is unknown but there are some factors increasing its incidence, such as: traumatisms, infections, the reduction of the vascular supply of the circunjacent bone and the general systemic status. ozonized sunflower oil was used as the only drug to treat alveolitis in a group of patients, and a comparison was made with a control group in which alvogil eas used in addition to an oral antibiotic. the sample was composed of 100 adult patients distributed at random. cures were made every 72 hours, and there were as many visits to the dentist's office as it was required. the cure criterion taken into consideration was the formation of cicatrization tissue and the reduction or erradication of pain. 46 % of the patients were cured with oleozon and 41 % with alvogil. there were no significant differences between both groups. most of the patients needed 2 or 3 visits to the dentist's office in both groups, though it was observed a higher number of patients in the group treated with ozonized oil with marked differences (p=0,004) as regards the control group. no intolerance to oleoson was observed.
Aplicación de la ozonoterapia en el tratamiento de la alveolitis
OLGA CRUZ GUERRA,SILVIA MENéNDEZ CEPERO,MARíA E. MARTíNEZ JORDáN,. TERESITA CLAVERA VáZQUEZ
Revista Cubana de Estomatolog?-a , 1997,
Abstract: La etiología de la alveolitis es desconocida, pero existen factores que aumentan su incidencia como los traumatismos, las infecciones, la disminución del suministro vascular del hueso circunvecino y el estado sistémico general. En un grupo de pacientes se utilizó aceite de girasol ozonizado, Oleozon (como único medicamento), en el tratamiento de la alveolitis, y se comparó con un grupo control en el que se empleó Alvogil, además de antibiótico oral. La muestra fue de 100 pacientes adultos distribuidos aleatoriamente. Se realizaron curas cada 72 horas y tantas visitas a consulta como el caso lo requiriera. El criterio de curación tomado en cuenta fue la formación de tejido de cicatrización y la disminución o eliminación del dolor. Se alcanzó el 46 % de pacientes curados con Oleozon y el 41 % con Alvogil, sin diferencias significativas entre ambos grupos. El mayor número de pacientes necesitó de 2 a 3 visitas a consulta en los 2 grupos, aunque se observó que había un mayor número de pacientes en el grupo tratado con aceite ozonizado, con diferencias significativas (p=0,004) con respecto al grupo control. No se observó intolerancia al Oleozon. The etiology of alveolitis is unknown but there are some factors increasing its incidence, such as: traumatisms, infections, the reduction of the vascular supply of the circunjacent bone and the general systemic status. Ozonized sunflower oil was used as the only drug to treat alveolitis in a group of patients, and a comparison was made with a control group in which Alvogil eas used in addition to an oral antibiotic. The sample was composed of 100 adult patients distributed at random. Cures were made every 72 hours, and there were as many visits to the dentist's office as it was required. The cure criterion taken into consideration was the formation of cicatrization tissue and the reduction or erradication of pain. 46 % of the patients were cured with Oleozon and 41 % with Alvogil. There were no significant differences between both groups. Most of the patients needed 2 or 3 visits to the dentist's office in both groups, though it was observed a higher number of patients in the group treated with ozonized oil with marked differences (p=0,004) as regards the control group. No intolerance to Oleoson was observed.
Thalassia testudinum, una planta marina con potencialidades de uso terapéutico Thalassia testudinum, a sea plant with great therapeutical potentialities
Eliane de la Torre Nú?ez,Idania Rodeiro Guerra,Roberto Menéndez Soto del Valle,Dalmis Pérez Carrasco
Revista Cubana de Plantas Medicinales , 2012,
Abstract: Introducción: las plantas medicinales son todas aquellas que contienen un principio activo o más, los cuales, administrados con la dosis adecuada, producen un efecto curativo a las enfermedades del hombre y los animales. El hecho de contener más de un principio activo hace que una planta medicinal pueda servir para tratar diferentes afecciones o trastornos. Objetivo: analizar los beneficios y las potencialidades terapéuticas de la planta marina Thalassia testudinum a partir de una revisión de la información existente y los principales resultados de las investigaciones realizadas sobre este organismo marino. Desarrollo: los productos naturales con propiedades terapéuticas han sido muy utilizados en la medicina tradicional. Indudablemente, los extractos de plantas de origen terrestre han representado hasta el presente una de las fuentes de mayor interés para la obtención de fitofármacos. Sin embargo, una fuente útil aún no explorada lo suficiente son los organismos marinos, que al evolucionar y vivir en condiciones ecológicas únicas y como resultado de su gran diversidad taxonómica en relación con la de los organismos terrestres, pueden sintetizar moléculas que no tienen equivalencia con las encontradas hasta el presente en estos últimos. Eso puede derivar en la obtención de estructuras químicas novedosas con efectos farmacológicos sui generis, tal es el caso de la fenograma marina Thalassia testudinum. De esta planta se ha obtenido un extracto rico en estructuras polifenólicas con potencialidades de uso terapéutico asociadas a la gran variedad de efectos beneficiosos que se le han descrito en los estudios realizados hasta el momento, como son sus propiedades antiinflamatorias, citoprotectoras, antioxidantes y neuroprotectoras, lo cual hace de este nuevo producto en desarrollo un posible fitofármaco. Conclusiones: los organismos marinos constituyen una fuente novedosa en la obtención de nuevos fitofármacos y suplementos nutricionales con una gran utilidad en la salud y la alimentación del hombre. Introduction: medicinal plants are those which contain one or more active principles that have a curative effect upon some illnesses which affect men and animals, whenever it is adequately administered. When one plant contains more than one active principle, it can be used to treat different ailments or body disorders. Objective: to analyze the benefits and therapeutic potentialities of the sea plant Thalassia testudinum based on the existent information and in the main results of research works about this sea organism. Development: natural products with therapeut
Actividad antimicrobiana y toxicidad de un extracto acuoso de Boerhaavia erecta L
Guerra Ordo?ez,Marta; Vega Montalvo,Raiza; Rivero Martínez,Reinaldo; Menéndez Castillo,Rosa; Gutiérrez Pulido,Alina; Guerra Sardinas,Isbel;
Revista Cubana de Plantas Medicinales , 2004,
Abstract: the in vitro antimicrobial activity and the acute oral toxicity of an aqueous extract of boerhaavia erecta l. were evaluated. the assay of dilutions in liquid medium was used, and the minimum inhibitory and the minimum microbicidal concentration against microorganisms of human clinical interest were determined. toxicity was evaluated by the limited dose test according to the norm of oecd. like other species of the genus, the extract showed antifungal activity against microsporum canis. as the dose used in the assay caused no mortality, the extract was considered as non toxic.
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