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Search Results: 1 - 10 of 27631 matches for " Hu Guangtao "
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VARIATION OF SLOPE FAILURE ON UPPER REACHES AREA OF HANJIANG RIVER
汉江上游斜坡破坏的变异

Hu Guangtao,
胡广韬

环境科学学报 , 1986,
Abstract: The natural geological conditions of slope zone on upper reaches of Hanjiang River were investigated. The type and the cause of failure were also studied. Two kinds of slope environments were distinguished as "natural geological slope environment" developed naturally and "engineering geological slope environment" caused by economic activity.
A Real-Time Urban Traffic Detection Algorithm Based on Spatio-Temporal OD Matrix in Vehicular Sensor Network  [PDF]
Ke Zhang, Guangtao Xue
Wireless Sensor Network (WSN) , 2010, DOI: 10.4236/wsn.2010.29080
Abstract: Currently, there are kinds of algorithms in order to detect real-time urban traffic condition. Most of these approaches consider speed of vehicles as a main metric to describe traffic situation. In this paper, we find out two important observations through several experiments. (1) In urban city, the speed of vehicles is influenced significantly by some factors such as traffic lights delay and road condition. The actual situation rarely satisfy hypothesis required for these solutions. Therefore, these traditional algorithms do not work well in practical environment. (2) Traffic volume on a road segment shows strong pattern and changes smoothly at adjacent time. This feature of traffic volume inspires us to define a metric: traffic-rate, which is used to detect traffic condition in real time. In our solution, we develop a novel traffic-detection algorithm based on original- destination (OD) matrix. We illustrate our approach and measure its performance in real environment. The performance evaluations confirm the effectiveness of our algorithm.
Trace Interpolation Algorithm Based on Intersection Vehicle Movement Modeling  [PDF]
Jinwei Shen, Guangtao Xue
Wireless Sensor Network (WSN) , 2010, DOI: 10.4236/wsn.2010.211099
Abstract: Real vehicle tracking data play an important role in the research of routing in vehicle sensor networks. Most of the vehicle tracking data, however, were collected periodically and could not meet the requirements of real-time by many applications. Most of the existing trace interpolation algorithms use uniform interpolation methods and have low accuracy problem. From our observation, intersection vehicle status is critical to the vehicle movement. In this paper, we proposed a novel trace interpolation algorithm. Our algorithm used intersection vehicle movement modeling (IVMM) and velocity data mining (VDM) to assist the interpolation process. The algorithm is evaluated with real vehicle GPS data. Results show that our algorithm has much higher accuracy than traditional trace interpolation algorithms.
On the Dynamic Mechanism of Disintegration Colliding and Shock Damming by Highspeed Rocky Landslide
高速岩质滑坡撞击弹落冲击夯实成坝的动力学机理

Cheng Qiangong,Hu Houtian,Hu Guangtao,
程谦恭
,胡厚田,胡广韬

岩石力学与工程学报 , 2000,
Abstract: Using the principle of elastic dynamics of rock and the variational method of elastic mechanics, the dynamic mechanism is explored of landslide damming by shock wave when the landslide mass is sharply disintegrated and collides with high moving speed. The calculating formula is proposed to deal with the compaction density of rock and soil. Based on the in-situ geotechnical testing, the proposed landslide dynamics is confirmed.
Cloning and identification of a novel human glioma differentiation related geneGDR1
Guangtao Li,Hulin Jin,Songnian Hu,Jian Jin,Chun Tu,Jiangang Yuan,Boqin Qiang
Chinese Science Bulletin , 2000, DOI: 10.1007/BF02884978
Abstract: In order to identify the genes associated with glioblastoma differentiation, some ESTs, expressed differentially in the control cell and the differentiated human glioblastoma cell line BT-325 induced by the all-trans retinoid acid, have been isolated by the method of DDRT-PCR. Of the 46 ESTs sequenced, 19 are from new genes. A full-length 1 535-bp cDNA, termed geneGDR1, has been isolated from the human cDNA library using the probe designed according to one of the novel ESTs, HGBB098. The open reading frame ofGDR1 gene encodes a putative protein containing 334 amino acid residues. Blast against the current GenBank DNA and protein sequence database did not reveal significant homology with any known proteins. RT-PCR shows thatGDR1 mRNA level increased in the differentiated BT-325 cells after being treated with RA. The different expression patterns ofGDR1 mRNA in human tissues have been detected through the multiple tissue Northern blot hybridization.
Face Illumination Modeling Method Based on the Face Image Multimode Decomposition of Riemannian Tensor
基于黎曼张量的人脸图像多模态分解光照建模方法

HU Bufa,HAO Guangtao,
胡步发
,郝广涛

中国图象图形学报 , 2009,
Abstract: 目前,人脸光照建模方法总是假设人脸满足朗伯凸模型、已知人脸表面法向量和反射率等条件,这与实际情况不符,建立的人脸光照模型也存在较大的偏差。为了解决这一问题,提出了一种新的人脸光照建模方法。该方法首先采用黎曼张量人脸图像多模态分解,建立人脸光照模型;然后基于改进的广义拉格朗日算法对人脸光照模型进行优化。理论分析和实验结果表明,该方法比光度立体学、球谐函数方法具有较高的精度和较强的实用性。
Cloning and identification of a novel human glioma differentiation related gene GDR1

LI Guangtao,JIN Hulin,HU Songnian,JIN Jian,TU Chun,YUAN Jiangang,QIANG Boqin,

科学通报(英文版) , 2000,
Abstract: In order to identify the genes associated with glioblastoma differentiation, some ESTs, expressed differentially in the control cell and the differentiated human glioblastoma cell line BT-325 induced by the all-trans retinoid acid, have been isolated by the method of DDRT-PCR. Of the 46 ESTs sequenced, 19 are from new genes. A full-length 1 535-bp cDNA, termed geneGDR1, has been isolated from the human cDNA library using the probe designed according to one of the novel ESTs, HGBB098. The open reading frame ofGDR1 gene encodes a putative protein containing 334 amino acid residues. Blast against the current GenBank DNA and protein sequence database did not reveal significant homology with any known proteins. RT-PCR shows thatGDR1 mRNA level increased in the differentiated BT-325 cells after being treated with RA. The different expression patterns ofGDR1 mRNA in human tissues have been detected through the multiple tissue Northern blot hybridization.
Mapping the Tail Fiber as the Receptor Binding Protein Responsible for Differential Host Specificity of Pseudomonas aeruginosa Bacteriophages PaP1 and JG004
Shuai Le, Xuesong He, Yinling Tan, Guangtao Huang, Lin Zhang, Renate Lux, Wenyuan Shi, Fuquan Hu
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0068562
Abstract: The first step in bacteriophage infection is recognition and binding to the host receptor, which is mediated by the phage receptor binding protein (RBP). Different RBPs can lead to differential host specificity. In many bacteriophages, such as Escherichia coli and Lactococcal phages, RBPs have been identified as the tail fiber or protruding baseplate proteins. However, the tail fiber-dependent host specificity in Pseudomonas aeruginosa phages has not been well studied. This study aimed to identify and investigate the binding specificity of the RBP of P. aeruginosa phages PaP1 and JG004. These two phages share high DNA sequence homology but exhibit different host specificities. A spontaneous mutant phage was isolated and exhibited broader host range compared with the parental phage JG004. Sequencing of its putative tail fiber and baseplate region indicated a single point mutation in ORF84 (a putative tail fiber gene), which resulted in the replacement of a positively charged lysine (K) by an uncharged asparagine (N). We further demonstrated that the replacement of the tail fiber gene (ORF69) of PaP1 with the corresponding gene from phage JG004 resulted in a recombinant phage that displayed altered host specificity. Our study revealed the tail fiber-dependent host specificity in P. aeruginosa phages and provided an effective tool for its alteration. These contributions may have potential value in phage therapy.
A STUDY OF COMPLEX ACCELERATED DYNAMICS MECHANISM OF HIGHSPEED LANDSLIDE BY ELASTIC ROCKY IMPULSE AND PEAK-RESIDUAL STRENGTH DROP
高速岩质滑坡临床弹冲与峰残强降复合启程加速动力学机理

Cheng Qiangong,Hu Houtian,Hu Guangtao,Peng Jianbing,
程谦恭
,胡厚田,胡广韬,彭建兵

岩石力学与工程学报 , 2000,
Abstract: 运用断裂力学和弹性力学的原理和方法,提出并分析了逆向层状岩体斜坡锁固段突然剪断时出现的"临床弹冲-峰残强降"复合加速动力学效应,推导出二维应力状态下高速岩质滑坡启程速度计算公式.这从理论上定量地论证了具有实际意义的滑坡动力学新机理.
A new approach for HIV-1 protease cleavage site prediction combined with feature selection  [PDF]
Yao Yuan, Hui Liu, Guangtao Qiu
Journal of Biomedical Science and Engineering (JBiSE) , 2013, DOI: 10.4236/jbise.2013.612144
Abstract:

Acquired immunodeficiency syndrome (AIDS) is a fatal disease which highly threatens the health of human being. Human immunodeficiency virus (HIV) is the pathogeny for this disease. Investigating HIV-1 protease cleavage sites can help researchers find or develop protease inhibitors which can restrain the replication of HIV-1, thus resisting AIDS. Feature selection is a new approach for solving the HIV-1 protease cleavage site prediction task and it’s a key point in our research. Comparing with the previous work, there are several advantages in our work. First, a filter method is used to eliminate the redundant features. Second, besides traditional orthogonal encoding (OE), two kinds of newly proposed features extracted by conducting principal component analysis (PCA) and non-linear Fisher transformation (NLF) on AAindex database are used. The two new features are proven to perform better than OE. Third, the data set used here is largely expanded to 1922 samples. Also to improve prediction performance, we conduct parameter optimization for SVM, thus the classifier can obtain better prediction capability. We also fuse the three kinds of features to make sure comprehensive feature representation and improve prediction performance. To effectively evaluate the prediction performance of our method, five parameters, which are much more than previous work, are used to conduct complete comparison. The experimental results of our method show that our method gain better performance than the state of art method. This means that the feature selection combined with feature fusion and classifier parameter optimization can effectively improve HIV-1 cleavage site prediction. Moreover, our work can provide useful help for HIV-1 protease inhibitor developing in the future.

 

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