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Search Results: 1 - 10 of 80530 matches for " Hsiang-Chen Hsu "
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An Analytical Approach for Analysis of Slider Bearings with Non-Newtonian Lubricants
Li-Ming Chu,Hsiang-Chen Hsu,Jiann-Lin Chen
Advances in Mechanical Engineering , 2014, DOI: 10.1155/2014/404759
Abstract: In this study, a regular perturbation technique is utilized to derive the modified Reynolds equation which is applicable to power-law lubricant. The performance of slider bearings including pressure distributions, velocity distributions, film thickness, load capacity, flow rate, shear force, and friction coefficient is also derived analytically for various , flow indices ( ), and outlet film thicknesses ( ). These analytical solutions are clear to find the effects of the operation parameters rather than numerical methods. It can be simply and fast used for engineers. Subsequently, these proposed analytical solutions are used to analyze the lubrication performance of slider bearing with the power-law fluids. 1. Introduction In all geometric-shaped sliders, wedge sliders provide the simplest support for fluid lubrication, and thus they are usually used as components of thrust slider bearings. With the development of modern machines, polymer oil, especially engine oil for vehicles such as multigrade crank case oil, is usually added to the lubricating oil in order to effectively reduce the friction loss of machine parts. However, such lubricants containing polymer belong to the non-Newtonian fluid type. As a result, the non-Newtonian characteristics of lubricants have become important. In recent years, there have been a great number of models used to describe non-Newtonian fluids. Among them, the power-law model is the simplest and most widely used. Safar and Shawki [1] divided fluids into three different categories: Newtonian fluid, , which is assumed as the type of ordinary pure fluid and gas; dilatant fluids or shear-thickening fluids, , which exhibit an increase in apparent viscosity with increasing shear rate; pseudoplastic fluids, , which are characterized by linearity at extremely low and extremely high shear rates. With regard to investigating slider bearings, many scholars [2–4] have derived closed-form solutions of Newtonian fluid for different slider bearings shapes. Hamrock [5] analyzed pressure distributions, velocity distributions, maximum pressure, film thickness, load capacity per unit width, flow rate, and friction coefficient of fixed-incline slider bearings with Newtonian fluid. As mentioned above, the closed-form solutions focus on simple geometry shape and Newtonian fluid. However, many experiments have shown that base oil blended with long-chain additives to a Newtonian fluid gives the most preferable lubricant results and can improve the load-carrying capacity and reduce the friction parameter [6, 7]. Therefore, the use of
Microfluidic Synthesis of Microfibers for Magnetic-Responsive Controlled Drug Release and Cell Culture
Yung-Sheng Lin, Keng-Shiang Huang, Chih-Hui Yang, Chih-Yu Wang, Yuh-Shyong Yang, Hsiang-Chen Hsu, Yu-Ju Liao, Chia-Wen Tsai
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0033184
Abstract: This study demonstrated the fabrication of alginate microfibers using a modular microfluidic system for magnetic-responsive controlled drug release and cell culture. A novel two-dimensional fluid-focusing technique with multi-inlets and junctions was used to spatiotemporally control the continuous laminar flow of alginate solutions. The diameter of the manufactured microfibers, which ranged from 211 μm to 364 μm, could be well controlled by changing the flow rate of the continuous phase. While the model drug, diclofenac, was encapsulated into microfibers, the drug release profile exhibited the characteristic of a proper and steady release. Furthermore, the diclofenac release kinetics from the magnetic iron oxide-loaded microfibers could be controlled externally, allowing for a rapid drug release by applying a magnetic force. In addition, the successful culture of glioblastoma multiforme cells in the microfibers demonstrated a good structural integrity and environment to grow cells that could be applied in drug screening for targeting cancer cells. The proposed microfluidic system has the advantages of ease of fabrication, simplicity, and a fast and low-cost process that is capable of generating functional microfibers with the potential for biomedical applications, such as drug controlled release and cell culture.
Four wave mixing study on coalescence overgrowth of GaN nanocolumns on sapphire
Hsiang-Chen Wang,Chun-Ming Yeh,Tsung-Yi Tang,C. C. Yang,T. Malinauskas,K. Jarasiunas
Physics , 2010,
Abstract: Coalescence overgrowth of pattern-grown GaN nanocolumns (NC) on c-plane sapphire substrate with metal organic chemical vapour deposition is demonstrated. The subsequent coalescence overgrowth opens a possibility for dislocation reduction due to the lateral strain relaxation in columnar geometry. We present further growth optimization and innovative characterization of MOCVD layers, overgrown on the columnar structure with varying diameter of colums. Nanoimprint lithography was applied to open circular holes of 250, 300, 450, 600 nm in diameter on the SiO2 layer, deposited on the GaN layer on c-plane sapphire template.
Crystallinity Improvement of ZnO Thin Film on Different Buffer Layers Grown by MBE
Shao-Ying Ting,Po-Ju Chen,Hsiang-Chen Wang,Che-Hao Liao,Wen-Ming Chang,Ya-Ping Hsieh,C. C. Yang
Journal of Nanomaterials , 2012, DOI: 10.1155/2012/929278
Abstract: The material and optical properties of ZnO thin film samples grown on different buffer layers on sapphire substrates through a two-step temperature variation growth by molecular beam epitaxy were investigated. The thin buffer layer between the ZnO layer and the sapphire substrate decreased the lattice mismatch to achieve higher quality ZnO thin film growth. A GaN buffer layer slightly increased the quality of the ZnO thin film, but the threading dislocations still stretched along the c-axis of the GaN layer. The use of MgO as the buffer layer decreased the surface roughness of the ZnO thin film by 58.8% due to the suppression of surface cracks through strain transfer of the sample. From deep level emission and rocking curve measurements it was found that the threading dislocations play a more important role than oxygen vacancies for high-quality ZnO thin film growth.
Vascularized Composite Allograft Rejection Is Delayed by Intrajejunal Treatment with Donor Splenocytes without Concomitant Immunosuppressants
Christopher Glenn Wallace,Chia-Hung Yen,Hsiang-Chen Yang,Chun-Yen Lin,Ren-Chin Wu,Wei-Chao Huang,Jeng-Yee Lin,Fu-Chan Wei
Clinical and Developmental Immunology , 2012, DOI: 10.1155/2012/704063
Abstract: Background. Mucosal or oral tolerance, an established method for inducing low-risk antigen-specific hyporesponsiveness, has not been investigated in vascularized composite allograft (VCA) research. We studied its effects on recipient immune responses and VCA rejection. Methods. Lewis rats (; TREATED) received seven daily intrajejunal treatments of splenocytes from semiallogeneic Lewis-Brown-Norway rats (LBN) or vehicle (; SHAM). Recipients’ immune responses were assessed by mixed lymphocyte reaction (MLR) against donor antigen and controls. Other Lewis (; TREATED/VCA) received LBN hindlimb VCA and daily intrajejunal treatments of LBN splenocytes, or LBN VCA without treatment (; SHAM/VCA), until VCAs rejected. Recipients’ immune responses were characterised and VCAs biopsied for histopathology. Immunosuppressants were not used. Results. LBN-specific hyporesponsiveness was induced only in treated Lewis recipients. Treatment significantly reduced MLR alloreactivity, significantly reduced VCA rejection on histopathology, and significantly delayed clinical VCA rejection (; TREATED/VCA mean 9.6 versus 6.0 days for SHAM/VCA). Treatment significantly increased immunosuppressive IL-10/IL-4/TGF-β production and significantly decreased proinflammatory IFN-γ/TNF-α. Conclusion. Jejunal exposure to antigen conferred donor specific hyporesponsiveness that delayed VCA rejection. This method may offer a low-risk adjunctive treatment option to help protect VCAs from rejection.
Vascularized Composite Allograft Rejection Is Delayed by Intrajejunal Treatment with Donor Splenocytes without Concomitant Immunosuppressants
Christopher Glenn Wallace,Chia-Hung Yen,Hsiang-Chen Yang,Chun-Yen Lin,Ren-Chin Wu,Wei-Chao Huang,Jeng-Yee Lin,Fu-Chan Wei
Journal of Immunology Research , 2012, DOI: 10.1155/2012/704063
Abstract: Background. Mucosal or oral tolerance, an established method for inducing low-risk antigen-specific hyporesponsiveness, has not been investigated in vascularized composite allograft (VCA) research. We studied its effects on recipient immune responses and VCA rejection. Methods. Lewis rats ( ; TREATED) received seven daily intrajejunal treatments of splenocytes from semiallogeneic Lewis-Brown-Norway rats (LBN) or vehicle ( ; SHAM). Recipients’ immune responses were assessed by mixed lymphocyte reaction (MLR) against donor antigen and controls. Other Lewis ( ; TREATED/VCA) received LBN hindlimb VCA and daily intrajejunal treatments of LBN splenocytes, or LBN VCA without treatment ( ; SHAM/VCA), until VCAs rejected. Recipients’ immune responses were characterised and VCAs biopsied for histopathology. Immunosuppressants were not used. Results. LBN-specific hyporesponsiveness was induced only in treated Lewis recipients. Treatment significantly reduced MLR alloreactivity, significantly reduced VCA rejection on histopathology, and significantly delayed clinical VCA rejection ( ; TREATED/VCA mean 9.6 versus 6.0 days for SHAM/VCA). Treatment significantly increased immunosuppressive IL-10/IL-4/TGF-β production and significantly decreased proinflammatory IFN-γ/TNF-α. Conclusion. Jejunal exposure to antigen conferred donor specific hyporesponsiveness that delayed VCA rejection. This method may offer a low-risk adjunctive treatment option to help protect VCAs from rejection. 1. Introduction The technical feasibility of transplanting vascularized composite allografts (VCA) such as of hand/forearm, larynx, partial face, and others is not disputed [1–5]. However, reconstructive VCA is unlikely to become widely available until either the risk profiles of lifelong immunosuppressant drugs become more acceptable or a safe method of donor-specific VCA tolerance induction applicable to humans is devised [6, 7]. Although transplantation tolerance has been established in many experimental models and anecdotal incidents of tolerance in humans can be found in the literature, efforts to replicate the state safely and reliably in humans have proven futile [8, 9]. Another method to reduce the attendant risks of nonspecific immunosuppression may be to induce donor-specific hyporesponsiveness [7, 10]. Although this is not transplantation tolerance, such a state may decrease the dosages required to maintain the allotransplant. Enteral (usually oral) administration of appropriate antigens can specifically suppress development or progression of experimental autoimmunities such as
Unripe Fruit Extracts of Mangifera indica L. Protect against AGEs Formation, Melanogenesis and UVA-Induced Cell Damage  [PDF]
Chin-Hsiu Yu, Yu-Ting Lin, Hsiang-Ling Su, Kai-Wen Kan, Fu-Chen Liu, Shan-Yu Lin, Yu-Ming Chung, Hsin-Fen Hsu, Yung-Hsiang Lin
Food and Nutrition Sciences (FNS) , 2019, DOI: 10.4236/fns.2019.102014
Abstract: In this study, we explored the effects of unripe fruit extracts of Mangifera indica L. on the anti-aging activity in skin cells. Mangifera indica L. is a popular economical and medicinal plant with numerous health-beneficial properties. The aqueous extracts of unripe fruit of Mangifera indica L. were obtained and subjected to HPLC and NMR analyses for the identification of bioactive compounds. The anti-glycation effect of Mango unripe fruit extracts was monitored by in vitro model system of AGEs (Advanced glycation end products) formation. Mango unripe fruit extracts significantly inhibited the AGEs formation in a dose-dependent manner. Meanwhile, Mango unripe fruit extracts possessed a comparable efficiency to commercialized Kojic acids in the inhibition of melanogenesis in B16-F10 melanoma cells. The UVA-induced cell damages can be prevented and repaired by Mango unripe fruit extracts in skin fibroblast CCD-966SK. Compared to the untreated control, Mango unripe fruit extracts significantly increased the cell viability while being applied before (36%) or after (43%) UVA irradiation. These results verified the potential application of Mango unripe fruit extracts in the skin protection and recovery from UVA irradiation, as well as the suppression of AGEs formation and melanogenesis.
Exploring the Relationship between Quality of Sleep and Learning Satisfactions on the Nursing College Students  [PDF]
Hsiu-Chin Hsu, Ting-En Chen, Chia-Hsuan Lee, Whei-Mei Jean Shih, Mei-Hsiang Lin
Health (Health) , 2014, DOI: 10.4236/health.2014.614206
Abstract: Background and Aim: Quality of sleep is essential element for learning and memory. Students’ learning performance may be affected by sleep. The purpose of this study was to explore the relationship between quality of sleep and learning satisfaction on nursing college students. Design and Participants: A cross-sectional with correlation study design was employed. 200 students were recruited from the nursing college. Pittsburgh Sleep Quality Index and Learning Satisfaction Scale were used for data collection. SPSS for window 17.0 was used for data analysis. Results: Findings showed: 1) 53% of participants rated their sleep quality as poor; 2) the global learning satisfaction of participants varied between highly satisfaction and satisfaction; 3) the global learning satisfaction was significantly negative related to “subjective sleep quality”, “use the sleep pill”, and “daytime dysfunction” (p < 0.05), finally, students who were interested in nursing can be explained 10.2% of the total amount of variances in learning satisfaction. Conclusions: The findings can provide information regarding nursing students’ sleep status and learning satisfaction to school teacher. The information would be helpful as evidences when laying out nursing curriculum to strengthen students’ sleep hygiene and learning of affective domain in the future.
Some Reflections in Phenomenology and Psychoanalysis
Hsiang Hsu
Indo-Pacific Journal of Phenomenology , 2008,
Abstract: This paper examines the origin of phenomenology, and delineates several of its significant developments and refractions, in order to arrive at a renewed conception of phenomenological theory and practice: a future phenomenology that can, it is argued, articulate productively with certain grounds opened up by psychoanalysis. Indo-Pacific Journal of Phenomenology, Volume 8, Edition 1 May 2008
Sustaining Client Relationships in the Contract Manufacturer Own-Brand Building Process: The Case of a Smartphone Firm
Feng Hsu Liu,Lu-Jui Chen,Hsiang-Heng Chen
International Journal of Business and Management , 2011, DOI: 10.5539/ijbm.v6n7p59
Abstract: Whereas maintaining buyer–supplier relationships has been widely discussed in the literature, sustaining relationships with clients (buyers) while contract manufacturers (suppliers) pursue own-brand building has been relatively unexplored. This in-depth case study shows how an electronics contract manufacturer sustained its client relationships while building its own brand. The research framework consists of two subprocesses: competence leveraging and competence building. We argue that some of the strategies involved in these two processes can explain how a contract manufacturer can succeed in maintaining client relationships while pursuing own-brand building.
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