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Search Results: 1 - 10 of 31884 matches for " How-Wen Ko "
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Good Response to Gefitinib for Lung Adenocarcinoma with Hyperamylasemia: A Case Report
How-Wen Ko,Ying-Huang Tsai,Chih-Teng Yu,Chun-Yao Huang
Chang Gung Medical Journal , 2008,
Abstract: Hyperamylasemia in patients with bronchogenic carcinoma has been reported rarely.Gefitinib, an oral tyrosine kinase inhibitor of epidermal growth factor receptor (EGFR) signaling,has shown activity for treating patients with refractory advanced non-small cell lungcancer (NSCLC). This report describes a case of lung adenocarcinoma coexisting withhyperamylasemia in a 67-year-old man. Abdominal computed tomograhy and ultrasonographydemonstrated a normal pancreas. A mutational analysis of the EGFR gene indicated anin-frame deletion at exon 19. He underwent treatment with gefitinib. Chest radiography follow-up showed a partial response and the amylase level also decreased to normal. We suggestthat treatment with gefitinib is an effective therapeutic option for this rare patient subset.
Erlotinib-associated Near-fatal Interstitial Pneumonitis in A Patient with Relapsed Lung Adenocarcinoma
Chun-Liang Chou,How-Wen Ko,Chih-Wei Wang,Chih-Teng Yu
Chang Gung Medical Journal , 2010,
Abstract: Erlotinib (Tarceva ) is a human epidermal growth factor receptor (EGFR) tyrosinekinase inhibitor used for treatment of locally advanced or metastatic non-small cell lung cancer(NSCLC) after failure of at least one prior chemotherapy regimen. Interstitial lung disease,associated with gefitinib (Iressa ) use, has been reported in approximately 1% ofpatients worldwide. However, the adverse pulmonary effects of erlotinib remain poorly documented.Reviewed English language publications in MEDLINE and PubMed suggest thatthis report is to be the first case report in English of a histologically-confirmed case of nearfatalinterstitial pneumonitis with acute lung injury, associated with erlotinib, in East Asianpatients. Physicians are hereby encouraged to promptly evaluate new or worsening pulmonarysymptoms so that they can detect early radiographic signs of pulmonary toxicity inpatients on erlotinib. If toxicity is confirmed, erlotinib should be discontinued and thepatient treated appropriately. The case presented suggests that the outcome of erlotinib-associatedpulmonary toxicity with acute respiratory failure may be favorable with adequateearly management.
Enhanced Solar Cell Conversion Efficiency Using Birefringent Liquid Crystal Polymer Homeotropic Films from Reactive Mesogens
Gwomei Wu,Li-Hang Hsieh,How-Wen Chien
International Journal of Molecular Sciences , 2013, DOI: 10.3390/ijms141121319
Abstract: Novel birefringent liquid crystal polymer homeotropic films have been coated on semiconductor solar cells to improve the effective incident sunlight angles. The liquid crystal polymer precursor, based on reactive mesogens, is fluidic and flows like liquid. It would distribute uniformly on the solar cell sample surface by any traditional coating technique. The birefringence for light, due to the liquid crystal retardation properties, manipulated the optical length and the deflection of incident light, thus allowed an increase in the energy conversion efficiency. The expensive sunlight tracking systems could be avoided. The processing parameters can be tuned such as different mesogen concentrations and plate speeds of spin-coating. The results showed that the solar cell conversion efficiency was improved from 14.56% to 14.85% at an incident sunlight angle of 15°. It was further improved from 13.40% to 13.81% when the angle was 30°. The interesting angular dependency on solar cell efficiency enhancement has been evaluated.
Food Sanitation Knowledge, Attitude, and Behavior for the University Restaurants Employees  [PDF]
Wen-Hwa Ko
Food and Nutrition Sciences (FNS) , 2011, DOI: 10.4236/fns.2011.27102
Abstract: The purpose of this study was to discuss the food sanitation knowledge, attitude, and behavior for the employees of university restaurants, and furthermore, to explain the interrelations of these various were occurring at school. A questionnaire survey procedure was used. Each two constructs of food sanitation attitude and behavior were analyzed by factor analysis. Data was analyzed by description, Pearson’s correlation and multiple regression analysis. The correctness rate toward the whole sanitation knowledge of trials was 70%. The overall attitude toward food sanitation was prone to positive and the attitude of employee self-responsibility was superior to the attitude of food sanitation practice. The sanitary guiding behavior was better than the sanitary habit behavior; and there was a significant relationship indicated through Pearson correlation analysis among three various. The sanitation knowledge and sanitation attitude showed a 42.6% predictive power to behavior, the attitude was mediated between knowledge and behavior. The university restaurant employees shared a more pessimistic view toward the benefits of training and the institutions could establish a committee for monitoring food nutrition and sanitation. It provides valuable information for development employees training while seeking to raise school restaurant food safety levels.
Foodservice Quality: Identifying Perception Indicators of Foodservice Quality for Hospitality Students  [PDF]
Wen-Hwa Ko, Li-Jung Su
Food and Nutrition Sciences (FNS) , 2014, DOI: 10.4236/fns.2014.52017

This study uses an expert perspective to identify indicators of foodservice quality as perceived by hospitality students. A 3-round modified Delphi method and an expert panel comprising culinary arts instructors, master chefs with >10 years of experience, and senior foodservice industry executive managers were used to define and identify these indicators. The developed foodservice quality framework includes 2 categories, the product and customer, which comprise 57 indicators in 6 dimensions. The results of this study provide a clear direction for further studies and applications for hospitality professionals, educators, and students.

Measuring the second order correlation function and the coherence time using random phase modulation
Chen-How Huang,Yung-Hsiang Wen,Yi-Wei Liu
Physics , 2015,
Abstract: A new approach to measure the second order correlation function $g^{(2)}$ and the coherence time was investigated. The $g^{(2)}$ was calculated from the photon pair time interval distribution by direct numerical self-convolution with the high order correction. The accuracy of this method was examined using an optical fiber based Hanbury-Brown-Twiss interferometer with a pseudo-thermal light source. We found that the significance of the high order correction is related to the factor $\bar{I}\tau_{c}$, which is the overlapping of the photon wave packets. A novel technique was also demonstrated to measure the coherence time $\tau_c$ of a light source using the random phase modulation. In comparison with the conventional self-heterodyne detection, this method is more suitable for a weak light source with a long coherence time.
Anisotropic flow in Cu+Au collisions at $\sqrt{s_{NN}}=200$ GeV
Lie-Wen Chen,Che Ming Ko
Physics , 2005, DOI: 10.1103/PhysRevC.73.014906
Abstract: The anisotropic flow of charged hadrons in asymmetric Cu+Au collisions at the Relativistic Heavy Ion Collider is studied in a multi-phase transport model. Compared with previous results for symmetric Au+Au collisions, charged hadrons produced around midrapidity in asymmetric collisions are found to have a stronger directed flow $v_{1}$ and their elliptic flow $% v_{2} $ is also more sensitive to the parton scattering cross section. While higher-order flows $v_{3}$ and $v_{4}$ are small at all rapidities, both $% v_{1}$ and $v_{2}$ in these collisions are appreciable and show an asymmetry in forward and backward rapidities.
Rapidity and system size dependence of anisotropic flows in relativistic heavy ion collisions
Che Ming Ko,Lie-Wen Chen
Physics , 2005, DOI: 10.1016/j.nuclphysa.2006.06.080
Abstract: We report results from a multiphase transport (AMPT) model on the rapidity and system size dependence of charged hadron anisotropic flows in nuclear collisions at the Relativistic Heavy Ion Collider (RHIC).
$φ$ and $Ω$ production in relativistic heavy ion collisions in a dynamical quark coalescence model
Lie-Wen Chen,Che Ming Ko
Physics , 2006, DOI: 10.1103/PhysRevC.73.044903
Abstract: Based on the phase-space information obtained from a multi-phase transport model within the string melting scenario for strange and antistrange quarks, we study the yields and transverse momentum spectra of $\phi $ mesons and $\Omega $ ($\Omega ^{-}+\bar{\Omega}^{+}$) baryons as well as their anisotropic flows in Au+Au collisions at RHIC using a dynamical quark coalescence model that includes the effect due to quark phase-space distributions inside hadrons. With current quark masses and fixing the $\phi $ and $\Omega $ radii from fitting measured yields, we first study the ratio of the yield of $\Omega $ baryons to that of $\phi $ mesons as well as their elliptic and fourth-order flows as functions of their transverse momentum. How the elliptic and fourth-order flows of $\phi $ mesons and $\Omega $ baryons are related to those of strange and antistrange quarks is then examined. The dependence of above results on $\phi $ and $\Omega $ radii as well as on the strange quark mass is also studied.
System size dependence of elliptic flows in relativistic heavy-ion collisions
Lie-Wen Chen,Che Ming Ko
Physics , 2005, DOI: 10.1016/j.physletb.2006.01.037
Abstract: The elliptic flows in both Cu+Cu and Au+Au collisions at the Relativistic Heavy Ion Collider are studied in a multi-phase transport model. For both collisions at same reduced impact parameter and minimum bias collisions, the elliptic flow of partons in Cu+Cu collisions is about a factor of three smaller than that in Au+Au collisions at same energy. The reduction factor is similar to the ratio of the sizes of the two colliding systems and is also related to the combined effects of initial energy density and spatial elliptic deformation in the two reactions. A similar system size dependence is also seen in the elliptic flow of charged hadrons from minimum bias collisions.
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