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Search Results: 1 - 10 of 36838 matches for " Hong JM "
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Cost–utility analysis for platinum-sensitive recurrent ovarian cancer therapy in South Korea: results of the polyethylene glycolated liposomal doxorubicin/carboplatin sequencing model
Lee HY,Yang BM,Hong JM,Lee TJ
ClinicoEconomics and Outcomes Research , 2013,
Abstract: Hwa-young Lee,1 Bong-Min Yang,1 Ji-min Hong,1 Tae-Jin Lee,1 Byoung-Gie Kim,2 Jae-Weon Kim,3 Young-Tae Kim,4 Yong-Man Kim,5 Sokbom Kang61Graduate School of Public Health, Seoul National University, Seoul, South Korea; 2Department of Obstetrics and Gynecology, Samsung Medical Center, Seoul, South Korea; 3Department of Obstetrics and Gynecology, Seoul National University, Seoul, South Korea; 4Department of Obstetrics and Gynecology, Yonsei University, Seoul, South Korea; 5Department of Obstetrics and Gynecology, University of Ulsan, Ulsan, South Korea; 6Department of Obstetrics and Gynecology, National Cancer Center, Kyeonggi-do, South KoreaObjective: We performed a cost–utility analysis to assess the cost-effectiveness of a chemotherapy sequence including a combination of polyethylene glycolated liposomal doxorubicin (PLD)/carboplatin versus paclitaxel/carboplatin as a second-line treatment in women with platinum-sensitive ovarian cancer.Methods: A Markov model was constructed with a 10-year time horizon. The treatment sequence consisted of first- to sixth-line chemotherapies and best supportive care (BSC) before death. Cycle length, a time interval for efficacy evaluation of chemotherapy, was 9 weeks. The model consisted of four health states: responsive, progressive, clinical remission, and death. At any given time, a patient may have remained on a current therapy or made a transition to the next therapy or death. Median time to progressions and overall survivals data were obtained through a systematic literature review and were pooled using a meta-analytical approach. If unavailable, this was elicited from an expert panel (eg, BSC). These outcomes were converted to transition probabilities using an appropriate formula. Direct costs included drug-acquisition costs for chemotherapies, premedication, adverse-event treatment and monitoring, efficacy evaluation, BSC, drug administration, and follow-up tests during remission. Indirect costs were transportation expenses. Utilities were also derived from the literature. Costs and utilities were discounted at an annual rate of 5% per cycle.Results: PLD/carboplatin combination as the second line in the sequence is more effective and costly than paclitaxel/carboplatin combination, showing an additional US$21,658 per quality-adjusted life years. This result was robust in a deterministic sensitivity analysis except when median time to progression of second-line therapies and administration cost of PLD/carboplatin per administration cycle were varied. The probability of cost-effectiveness for PLD/carboplatin combina
Electron focusing, mode spectroscopy and mass enhancement in small GaAs/AlGaAs rings
J Liu,K Ismail,KY Lee,JM Hong,S Washburn
Physics , 1992, DOI: 10.1103/PhysRevB.47.13039
Abstract: A new electron focusing effect has been discovered in small single and coupled GaAs/AlGaAs rings. The focusing in the single ring is attributed solely to internal orbits. The focusing effect allows the ring to be used as a small mass spectrometer. The focusing causes peaks in the magnetoresistance at low fields, and the peak positions were used to study the dispersion relation of the one-dimensional magnetoelectric subbands. The electron effective mass increases with the applied magnetic field by a factor of $50$, at a magnetic field of $0.5T$. This is the first time this increase has been measured directly. General agreement obtains between the experiment and the subband calculations for straight channels.
Prediction of annual genetic gain and improvement lag between populations
JM Elsen
Genetics Selection Evolution , 1993, DOI: 10.1186/1297-9686-25-1-75
Abstract:
Biotechnical measures for improvement of fertility in cattle
JM Sreenan
Genetics Selection Evolution , 1980, DOI: 10.1186/1297-9686-12-4-405c
Abstract:
Production de soie et caractéristiques des glandes séricigènes de 13 races de ver à soie (Bombyx mori)
JM Fayard
Genetics Selection Evolution , 1978, DOI: 10.1186/1297-9686-10-2-259
Abstract:
Effets de la consanguinité sur deux caractères quantitatifs chez le ver a soie
JM Legay
Genetics Selection Evolution , 1971, DOI: 10.1186/1297-9686-3-4-487
Abstract:
Interactions géniteur × population des partenaires II. Détection par des expériences de sélection
JM Brun
Genetics Selection Evolution , 1984, DOI: 10.1186/1297-9686-16-4-455
Abstract:
Interactions géniteur × population des partenaires. III. Synthèse bibliographique
JM Brun
Genetics Selection Evolution , 1985, DOI: 10.1186/1297-9686-17-4-561
Abstract:
Paramètres du croisement entre 3 souches de lapin et analyse de la réponse à une sélection sur la taille de portée: caractères des portées à la naissance et au sevrage
JM Brun
Genetics Selection Evolution , 1993, DOI: 10.1186/1297-9686-25-5-459
Abstract:
évolution des modalités de recrutement des taureaux destinés a l'insémination artificielle
JM Duplan
Genetics Selection Evolution , 1969, DOI: 10.1186/1297-9686-1-2-187b
Abstract:
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