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Backpack Weight and Musculoskeletal Symptoms in Secondary School Students, Tehran, Iran
AR Shamsoddini,MT Hollisaz,R Hafezi
Iranian Journal of Public Health , 2010,
Abstract: Background: . The aim of this study was to investigate of relationship of musculoskeletal symptoms with weight of backpack in Tehran secondary school students. Methods: This cross-sectional study was performed in the city of Tehran in 2009. Two hundred thirteen students partici-pated in study. Nordic Musculoskeletal Questionnaire was used, asking about complaints of back, neck, and/or shoulders. Length and weight of the children were determined. Schoolbags were weighed, and the relative weight of the schoolbag was calculated. Results: Most prevalent discomfort was in shoulders as 38.1%, neck 27.6% and back 16.7%. Average difference of weight of backpack in sample that had musculoskeletal with other samples was significant (P< 0.05). Conclusion: .
Comparison of impacts of friction massage, stretching exercises and analgesics on pain relief in primary fibromyalgia syndrome: a randomized clinical trial
Amanollahi A,Khatibi A,Hollisaz MT,Shamseddini AR
Tehran University Medical Journal , 2013,
Abstract: Background: Stretching exercises and massage therapy are both suggested for pain relief in fibromyalgia syndrome. Previous studies have not proved their superiority over each other. This study compared the therapeutic effects of friction massage, stretching exercises, and analgesics on pain relief in patients with fibromyalgia syndrome.Methods: We evaluated 129 female patients with the diagnosis of primary fibromyalgia visited at the physical medicine clinics of Baqiyatallah Hospital in Tehran, Iran during 2010- 2011. Patients were randomly divided into three groups: the first group received 400 mg ibuprofen P.O. (3 times per day) and 25 mg nortriptyline (daily) P.O. as analgesic, the second group was treated by friction massage and the third group performed stretching exercises. Patients were assessed three times (initially, after one and four weeks) by visual analogue scale (VAS).Results: The mean age of participants was 60.46 years. The mean age in each treatment group was 46.66 years in medication group, 46.73 years in stretching group and 46.65 years in friction massage group. Changes in VAS score over 4 weeks were 2.4, 3.1 and 1.9, in the first, second, and third groups, respectively. The changes in VAS were significantly different in the first and second groups rather than the controls (P<0.05).Conclusion: The effect of stretch exercise on pain relief was similar to analgesics, but it was more effective than friction massage. Moreover, the therapeutic effect of stretching exercise on pain relief upon four weeks was more permanent than friction massage but it was similar to analgesics.
Trends in Prevalent Injuries among Iranian Pilgrims in Hajj
SM Razavi,H Ziaee Ardakani,S Rajai,MT Hollisaz
Iranian Journal of Public Health , 2011,
Abstract: "nBackground: Annually millions of Muslims depart to Saudi Arabia for performing a religious pilgrimage called "Hajj". In this ceremony, pilgrims face numerous health hazards and injuries such as pressing in overcrowding, sliding, burning, fal-ling down, traffic accidents etc. The main purpose of this study was to determine the prevalence of injuries in Hajj period across 2004 to 2008."nMethods: This study was conducted on 253808 Iranian pilgrims on five consecutive years of Hajj ceremonies, from 2004 to 2008. We used a report sheet with 13 types of injuries and 13 mechanisms of these injuries. SPSS V13.5 soft ware was used for analyzing the data. ANOVA and independent sample t- test was conducted, and relationships were considered signifi-cant at P< 0.05."nResults: The most common injuries was "tissue contusions and ruptures "(about 76/10000), and "tendon lesions" (about 62/10000). In addition, the most common mechanism of injuries was "ankle sprain" (69/10000) during the five consecu-tive years. The prevalence of all fractures was about 49/10000 and the proportion of burning with hot water or fire was about 40/10000. Changes of all causes of the injuries were significant in this study (P< 0.05)."nConclusions: We have suggested some directions for preventing of injuries and related Injuries in Hajj, in this study.
Effects of Taping on Pain, Grip Strength and Wrist Extension Force in Patients with Tennis Elbow
Alireza Shamsoddini,Mohammad Taghi Hollisaz
Trauma Monthly , 2013, DOI: 10.5812/traumamon.12450
Abstract: Background: Tennis elbow (TE) is a common musculotendinous degenerative disorder of the extensor origin at the lateral humeral epicondyle. Different modes of treatment are used for management of tennis elbow.Objectives: This study investigated the effect of the taping technique (TT) on pain, grip strength and wrist extension force in treatment of tennis elbow.Patients and Methods: Thirty patients (16 men /14 women with a mean age of 32.2 years) with tennis elbow of their dominant arm participated in this study. Outcome measures were assessment of pain at the lateral aspect of the elbow, grip strength and wrist extension force before and five to ten minutes after application of elbow tape on the affected and unaffected arms. A Visual Analog Scale was used to assess pain. A dynamometer and a hand-held dynamometer were used for evaluation of grip strength and wrist extension force, respectively.Results: Among the variables, significant differences were found in wrist extension forces between effected and unaffected arms (P = 0.02). Changes in grip strength showed statically significant improvements in the affected arm compared to the unaffected arm (P = 0.03). Also, in assessment of pain at the lateral epicondyle, the mean change between affected and unaffected arms was significant, with P = 0.001.Conclusions: The taping technique, as applied in this study demonstrates an impressive effect on wrist extension force and grip strength of patients with TE. Elbow taping also reduces pain at the lateral aspect of the elbow in these patients.
A randomized clinical trial comparing hydrocolloid, phenytoin and simple dressings for the treatment of pressure ulcers [ISRCTN33429693]
Mohammad Hollisaz, Hossein Khedmat, Fatemeh Yari
BMC Dermatology , 2004, DOI: 10.1186/1471-5945-4-18
Abstract: Ninety-one stage I and stage II pressure ulcers of 83 paraplegic male victims of the Iran-Iraq war were randomly allocated to three treatment groups. Mean age and weight of the participants were 36.64 ± 6.04 years and 61.12 ± 5.08 kg, respectively. All the patients were managed in long term care units or in their homes for 8 weeks by a team of general practitioners and nurses, and the ulcer status was recorded as "Complete healing", "Partial healing", "Without improvement" and "Worsening".Complete healing of ulcers, regardless of location and stage, was better in the HD group than the PC [23/31(74.19%) vs 12/30(40%); difference: 34.19%, 95% CI = 10.85–57.52, (P < 0.01)] or the SD [23/31(74.19%) vs 8/30(26.66%); difference: 47.53%, 95% CI = 25.45–69.61, (P < 0.005)] groups. Complete healing of stage I ulcers in the HD group [11/13(85%)] was better than in the SD [5/11(45%); difference: 40%, 95% CI = 4.7–75.22, (P < 0.05)] or PC [2/9 (22%); difference: 63%, 95% CI = 29.69–96.3, (P < 0.005)] groups. Complete healing of stage II ulcer in the HD group [12/18 (67%)] was better than in the SD group [3/19(16%); difference: 51%, 95% CI = 23.73–78.26, (P < 0.005)], but not significantly different from the PC group [10/21 (48%); difference: 19%, 95% CI = -11.47–49.47, (P > 0.05)]. We performed a second analysis considering only one ulcer per patient (i.e. 83 ulcers in 83 patients). This "per patient" analysis showed that complete ulcer healing in the HD group was better than in the PC [20/28(71.4%) vs 11/28 (39.3%); difference: 32.1%, 95% CI = 7.4–56.7, (P < 0.01)] or SD [20/28(71.4%) vs 8/27 (29.6%); difference: 41.8%, 95% CI = 17.7–65.8, (P < 0.005)] groups.We deduced that HD is the most effective method investigated for treating stage I and II pressure ulcers in young paraplegic men.Skin ulcers caused by pressure and strains are known by various names: decubitus ulcer, bedsore, ischemic ulcer and pressure ulcer. "Pressure ulcer", which indicates the etiology of the lesion,
Using magnetic resonance to diagnose breast cancer and predict therapeutic response
MT Nelson
Breast Cancer Research , 2004, DOI: 10.1186/bcr834
Abstract: Women scheduled for a breast biopsy or scheduled to CT were recruited for our study. All studies were done with a 4 T MRI/MRS scanner. A baseline scan was done prior to the start of CT and 24 hours after CT. Suspicious lesions were identified and measured with a fat-suppressed high-resolution 3D FLASH image (Gd-TPA, 0.1 mmol/kg). Concentrations of tCho were quantified [3]. Each scan was interpreted by evaluation of lesion size, architecture, signal intensity, and tCho.Twenty-six out of 69 patients had infiltrative ductal carcinoma, 10/69 patients had infiltrative lobular carcinoma, 3/69 patients had ductal carcinoma in situ, 1/69 patients had lobular carcinoma in situ, and 29/69 patients were found to have benign breast lesions. Eight patients have been through CT. Tumor response was seen in six patients. MRS could detect decreased [tCho] within 24 hours after CT. In the six patients with decreased [tCho] at 24 hours, 100% showed diminished tumor size measured by MRI after 9 weeks of CT. However, the two patients with sustained or elevated [tCho] at 24 hours failed to have response to CT.Based on these results, we expect that the addition of MRS to MRI will provide a noninvasive technique for determining whether a breast abnormality is benign or malignant. Furthermore, the [tCho] measured at 24 hours appears to predict response to CT.
The methylenetetrahydrofolate reductase gene variant (C677T) in risk mothers with Down syndrome among Saudi population
MT Tayeb
Egyptian Journal of Medical Human Genetics , 2012,
Abstract: This unreeled study aimed to examine the relationship between the genetic polymorphisms C677T in MTHFR gene and mapped this figure with other ethnic populations. The present study examined 70 Saudi females (30 mothers with DS children plus 40 healthy mothers who gave birth only to healthy children) for C677T genotypes using restriction fragment length polymorphism (RFLP) of the amplified genomic DNA. The frequencies of the combined mutant genotypes CT and TT in the MTHFR gene were modestly represented in the case mothers compared to that in controls (33% vs. 35% and 13% vs. 10%) with no significance (OR 1.1, 95% CI, 0.41–2.77, p= 0.91). The frequency of the mutant 677T allele was 28% in the case mothers and plotted as a moderate value with different ethnic populations. The present study concluded that there was a null association between the common C677T polymorphism and the increased risk of Down syndrome, but the T allele slightly supported the increase of this maternal risk. The intermediacy to previous reports may probably be due to the small sample size, gene-nutritional-environmental factors, or the consequences of much social intermarriage between some Asian, Arab peoples and the Saudi community.
Association of the UCP2 –866G/A polymorphism with type 2 diabetes and obesity in Saudi population
MT Tayeb
Egyptian Journal of Medical Human Genetics , 2009,
Abstract: Background: Diabetes mellitus is emerging as a major public health problem allover the world particularly Saudi Arabia. Recent studies reported that Uncoupling Protein 2 (UCP2) was associated with obesity and type 2 diabetes (T2D). Aim of the Study: This study was conducted to clarify the contribution of polymorphism in UCP2 in obesity and T2D in the Saudi population. Subjects and Methods: The distribution of the –866G/A polymorphism was examined in a case-control study including samples from 110 obese patients, 81 T2D patients, 96 obese-T2D patients and 100 healthy unrelated Saudi subjects. The –866G/A polymorphism were determined by using PCR/RFLP (polymerase chain reaction/restriction fragment length polymorphism) techniques. Results: The results of this study showed that the frequency of the GG genotype was significantly higher in both obese and T2D patients (p-value= 0.0001, p-value= 0.014, respectively) compared with healthy control. The G allele was significantly associated with increase risk of obesity (odd ratio, OR: 3.3; 95% confidence interval, CI: 1.37-7.98), but not with T2D (OR, 1.97; Cl, 0.80-4.87). In obese-T2D patients group, no significant correlation with –866G/A polymorphism (p= 0.067; OR, 1.21; Cl, 0.25-2.80). This unreeled study suggested that the G allele of UCP2 –866G/A polymorphism was related to obesity, which indicated the possible role of this polymorphism in causing metabolic syndrome. Conclusion: This study concluded that the G allele of UCP2 –866G/A polymorphism might be related to obesity and T2D which might be used as a predictive marker for obesity and T2D. Key Words: T2D, Obesity, Uncoupling protein 2 (UCP2) gene, –866G/A polymorphism, Saudi population.
Application of magnetic motor stimulation for measuring conduction time across the lower part of the brachial plexus
Seyed Rayegani, Mohammad Hollisaz, Rahmatollah Hafezi, Shahriar Nassirzadeh
Journal of Brachial Plexus and Peripheral Nerve Injury , 2008, DOI: 10.1186/1749-7221-3-7
Abstract: This descriptive study was done on 112 upper limbs of healthy volunteers. Forty-six limbs belonging to men and sixty-six belonging to women were studied by magnetic stimulation of both motor cortex and brachial plexus and recording the evoked response in thenar and hypothenar muscles. Stimulation of the motor cortex gives rise to absolute latency of each nerve whereas stimulation of the brachial plexus results in peripheral conduction time. The difference between these two values was considered the central motor conduction time (CMCT).In summary the result are as follows; Cortex-thenar latency = 21.4 ms (SD = 1.7), CMCT-thenar = 9.6 ms (SD = 1.9), Cortex-hypothenar latency = 21.3 ms (SD = 1.8), CMCT-hypothenar = 9.4 ms (SD = 1.8).These findings showed that there is no meaningful difference between two genders. CMCT calculated by this method is a little longer than that obtained by electrical stimulation that is due to the more distally placed second stimulation. We recommend magnetic stimulation as the method of choice to calculate CMCT and its use for lower brachial plexus conduction time. This method could serve as a diagnostic tool for diagnosis of lower plexus entrapment and injuries especially in early stages.Magnetic motor stimulation is useful in the evaluation of a wide spectrum of nervous system disorders including multiple sclerosis, spinal cord lesions, motor neuron diseases, stroke, cervical spondylosis, intraoperative monitoring, epilepsy, pelvic floor disorders, movement disorders and some investigative conditions such as brain mapping studies [1-4].Technical advances in this method occurred during the 1980s and this method has gained approval for clinical applications involving diagnostic and prognostic issues [5,6]. Different techniques using magnetic stimulation and normal values for each technique have not yet been studied to the same extent as conventional electrodiagnostic techniques. Cortical magnetic stimulation has remarkable advantages over e
EFFECT OF SENSORY INTEGRATION THERAPY ON GROSS MOTOR FUNCTION IN CHILDREN WITH CEREBRAL PALSY
A.R. Shamsoddini,M.T. Hollisaz
Iranian Journal of Child Neurology , 2009,
Abstract: ObjectiveThe primary problem in children with cerebral palsy (CP), frequently referred for occupational therapy, is gross motor dysfunction. The current study was designed to investigate the effects of sensory integration therapy (SIT) on gross motor skills in CP patients.Materials & MethodsTwenty-four children with diplegic spastic CP were randomly divided into two groups: First group (n=14,6 girls, 8 boys), age range 2 to 6 years, mean age 3.9 years; the second or control group (n=10, 5 girls, 5 boys), age range 2 to 6 years, mean age 3.4 years. SIT training was given to the first group and only the home program was given for the second group. All children were evaluated with gross motor function measurement (GMFM 88) for rolling, sitting, crawling, standing and walking position before and after intervention. Treatment duration for both groups was 1 hour, 5 days per week for a period of 12 weeks.ResultsGross motor function in children of the case group improved significantly better that in the control group, after intervention in sitting (P=0.02), crawling (P=0.001) and standing (P=0.03) positions; however no significant difference was seen in rolling (P=0.65) and walking (P=0.69) ability assessment.ConclusionThis study showed the beneficial effects of the SIT training program for children with CP; the SIT intervention had a significantly positive effect on gross motor function in the children with diplegic spastic CP. Moreover the results of the present study showed that sensory integration and vestibular stimulation were effective in children with cerebral palsy.
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