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Search Results: 1 - 10 of 379 matches for " Hisao Ezaki "
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Choroidal and cutaneous metastasis from gastric adenocarcinoma
Shoichiro Kawai,Tsutomu Nishida,Yoshito Hayashi,Hisao Ezaki
World Journal of Gastroenterology , 2013, DOI: 10.3748/wjg.v19.i9.1485
Abstract: Choroidal or cutaneous metastasis of gastric cancer is rare. Gastrointestinal cancer was found in only 4% in patients with uveal metastasis. Choroidal metastasis from gastric cancer was reported in two cases in earlier literature. The frequency of gastric cancer as a primary lesion was 6% in cutaneous metastasis of men, and cutaneous metastasis occurs in 0.8% of all gastric cancers. We report a patient with gastric adenocarcinoma who presented with visual disorder in his left eye and skin pain on his head as his initial symptoms. These symptoms were diagnosed to be caused by choroidal and cutaneous metastasis of gastric adenocarcinoma. Two cycles of chemotherapy consisted of oral S-1 and intravenous cisplatin (SPIRITS regimen); this was markedly effective to reduce the primary gastric lesion and almost all the metastatic lesions.
Heavy metal behavior associated with soil cover used in the Bandeirantes Sanitary landfill, S o Paulo District
Anais da Academia Brasileira de Ciências , 2002,
Intrinsic Constraints on Sympodial Growth Morphologies of Azooxanthellate Scleractinian Coral Dendrophyllia
Asuka Sentoku, Yoichi Ezaki
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0063790
Abstract: Background Asexual increase occurs in virtually all colonial organisms. However, little is known about the intrinsic mechanisms that control asexual reproduction and the resultant morphologies of colonies. Scleractinian corals, both symbiotic (zoaxanthellate) and non-symbiotic (azooxanthellate) corals are known to form elaborate colonies. To better understand the growth mechanisms that control species-specific type of colony in azooxanthellate dendrophyllid scleractinian corals, we have studied details of the budding pattern in the sympodial colonies of Dendrophyllia boschmai and Dendrophyllia cribrosa. Principal Findings Budding exhibits the following regularities: (1) the two directive septa of offset corallites are oriented almost perpendicular to the growth direction of parent corallites; (2) offsets generally occur in either of the lateral primary septa that occur on one side of a corallite; the individuals thus show a definite polarity with respect to the directive septa, and only when branching dichotomously offsets occur in both primary septa; (3) the lateral corallites grow more-or-less diagonally upwards; and (4) the regularities and polarities are maintained throughout growth. Given these regularities, D. boschmai grows in a zigzag fashion by alternately budding on the right and left sites. In contrast, D. cribrosa grows helically by budding at a particular site. Conclusions/Significance The strict constraints on budding regularities and shifts in budding sites observed in the sympodial growth forms of corals greatly affect resulting morphologies in azooxanthellate coral colonies. A precise understanding of these intrinsic constraints leads to a fundamental comprehension of colony-forming mechanisms in modular organisms.
Potential global jamming transition in aviation networks
Takahiro Ezaki,Katsuhiro Nishinari
Physics , 2015, DOI: 10.1103/PhysRevE.90.022807
Abstract: In this paper, we propose a nonlinear transport model for an aviation network. The takeoff rate from an airport is characterized by the degree of ground congestion. Due to the effect of "surface congestion," the performance of an airport deteriorates because of inefficient configurations of waiting aircraft on the ground. Using a simple transport model, we performed simulations on a U. S. airport network and found a global jamming transition induced by local surface congestion. From a physical perspective, the mechanism of the transition is studied analytically and the resulting aircraft distribution is discussed considering system dynamics. This study shows that the knowledge of the relationship between a takeoff rate and a congestion level on the ground is vital for efficient air traffic operations.
Exact solution of a heterogeneous multi-lane asymmetric simple exclusion process
Takahiro Ezaki,Katsuhiro Nishinari
Physics , 2015, DOI: 10.1103/PhysRevE.84.061141
Abstract: We prove an exact solution of a multi-lane totally asymmetric simple exclusion process (TASEP) with heterogeneous lane-changing rates on a torus. The solution is given by a factorized form; that is, the TASEP in each lane and lane-changing transition can be separable because of the detailed balance conditions in lane-changing transition. Using the saddle point method, the current of particles is calculated in a simple form in a thermodynamic limit. It is notable that the current depends only on a set of lane-changing parameters, not on the configuration of lanes.
Balance network of asymmetric simple exclusion process
Takahiro Ezaki,Katsuhiro Nishinari
Statistics , 2012, DOI: 10.1088/1742-5468/2012/11/P11002
Abstract: We investigate a balance network of the asymmetric simple exclusion process (ASEP). Subsystems consisting of ASEPs are connected by bidirectional links with each other, which results in balance between every pair of subsystems. The network includes some specific important cases discussed in earlier works such as the ASEP with the Langmuir kinetics, multiple lanes and finite reservoirs. Probability distributions of particles in the steady state are exactly given in factorized forms according to their balance properties. Although the system has nonequilibrium parts, the expressions are well described in a framework of statistical mechanics based on equilibrium states. Moreover, the overall argument does not depend on the network structures, and the knowledge obtained in this work is applicable to a broad range of problems.
Representation of the Basic Laws of Thermodynamics in Quantum Mechanics  [PDF]
Akira Suzuki, Hisao Taira
Journal of Modern Physics (JMP) , 2018, DOI: 10.4236/jmp.2018.914155
Abstract: We propose a representation of the basic laws, namely the zeroth, first, second and third law, in quantum thermodynamics. The zeroth law is represented by some parameters (\"\") that specify respective quantum states. The parameters are the elements of thermodynamic state space\"\". The introduction of such parameters is based on a probabilistic nature of quantum theory. A quantum analog of the first law can be established by utilizing these parameters. The notion of heat in quantum systems is clarified from the probabilistic point of view in quantum theory. The representation of the second law can be naturally described in terms of these parameters introduced for the respective quantum systems. In obtaining the representation of quantum thermodynamics, consistency between quantum theory and classical thermodynamics should have been preserved throughout our formulation of quantum thermodynamics. After establishing the representation of the second law, the third law is discussed briefly. The relationship between thermodynamic temperatures and the parameters in \"\" is also discussed.
Serum Fucosylated Haptoglobin as a Novel Diagnostic Biomarker for Predicting Hepatocyte Ballooning and Nonalcoholic Steatohepatitis
Yoshihiro Kamada, Maaya Akita, Yuri Takeda, Shin Yamada, Hideki Fujii, Yoshiyuki Sawai, Yoshinori Doi, Hitomi Asazawa, Kotarosumitomo Nakayama, Kayo Mizutani, Hironobu Fujii, Takayuki Yakushijin, Masanori Miyazaki, Hisao Ezaki, Naoki Hiramatsu, Yuichi Yoshida, Shinichi Kiso, Yasuharu Imai, Norifumi Kawada, Tetsuo Takehara, Eiji Miyoshi
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0066328
Abstract: Nonalcoholic fatty liver disease (NAFLD) is a growing medical problem around the world. NAFLD patients with nonalcoholic steatohepatitis (NASH) can develop cirrhosis and hepatocellular carcinoma. The ability to distinguish NASH from simple steatosis would be of great clinical significance. Ballooning hepatocytes are characteristic of typical pathological NASH; here, the polarized secretion of proteins is disrupted due to destruction of the cytoskeleton. We previously reported that fucosylated glycoproteins are secreted into bile, but not into sera in normal liver. Therefore, we hypothesized that the fucosylation-based sorting machinery would be disrupted in ballooning hepatocytes, and serum fucosylated glycoproteins would increase in NASH patients. To confirm our hypothesis, we evaluated serum fucosylated haptoglobin (Fuc-Hpt) levels in biopsy-proven NAFLD patients (n = 126) using a lectin-antibody ELISA kit. Fuc-Hpt levels were significantly increased in NASH patients compared with non-NASH (NAFLD patients without NASH) patients. Interestingly, Fuc-Hpt levels showed a significant stepwise increase with increasing hepatocyte ballooning scores. Multiple logistic regression analysis showed that Fuc-Hpt levels were independent and significant determinants of the presence of ballooning hepatocytes. Moreover, Fuc-Hpt levels were useful in monitoring liver fibrosis staging. Next, to investigate the significance of serum Fuc-Hpt in a larger population, we measured Fuc-Hpt levels in ultrasound-diagnosed NAFLD subjects (n = 870) who received a medical health checkup. To evaluate NAFLD disease severity, we used the FIB-4 index (based on age, serum AST and ALT levels, and platelet counts). Fuc-Hpt levels increased stepwise with increasing FIB-4 index. Conclusion Measurement of serum Fuc-Hpt levels can distinguish NASH from non-NASH patients, and predict the presence of ballooning hepatocytes in NAFLD patients with sufficient accuracy. These results support the potential usefulness of measuring Fuc-Hpt levels in clinical practice.
Association Between Polymorphisms in Genes Related to Common Adult Diseases and Fetal Growth
Hisao Osada
Clinical Medicine Insights: Pediatrics , 2012,
Abstract: A close relationship between size at birth and occurrence of common adult diseases has been reported. As an explanation of this relationship, it has been hypothesized that the thrifty genotypes cause changes in growth efficiency during fetal period and diseases in later life. In the present study, we examined the association of fetal growth with genetic polymorphisms within the IGF2-INS-TH region and in the G protein gene. Analysis of the genes in the IGF2-INS-TH region suggests that thrifty genotype has the effect of accelerating fetal growth, but at the same time a genomic imprinting mechanism is also involved. Analysis of the G protein β3 subunit gene unveiled that the 825T allele in the mother may exert influence on fetal metabolic environment. By extending the analysis to other genomic regions related to common adult diseases using the same technique, the detailed role of genetic polymorphisms may be elucidated.
Rings decomposed into direct sums of J-rings and nil rings
Hisao Tominaga
International Journal of Mathematics and Mathematical Sciences , 1985, DOI: 10.1155/s0161171285000230
Abstract: Let R be a ring (not necessarily with identity) and let E denote the set of idempotents of R. We prove that R is a direct sum of a J-ring (every element is a power of itself) and a nil ring if and only if R is strongly €-regular and E is contained in some J-ideal of R. As a direct consequence of this result, the main theorem of [1] follows.
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