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Search Results: 1 - 10 of 3371 matches for " Hiroki Ito "
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Classification of involutions on Enriques surfaces
Hiroki Ito,Hisanori Ohashi
Mathematics , 2013,
Abstract: We present the classification of involutions on Enriques surfaces. We classify those into 18 types with the help of the lattice theory due to Nikulin. We also give all examples of the classification.
A remark on a priori estimate for the Navier-Stokes equations with the Coriolis force
Hiroki Ito,Jun Kato
Mathematics , 2015,
Abstract: The Cauchy problem for the Navier-Stokes equations with the Coriolis force is considered. It is proved that a similar a priori estimate, which is derived for the Navier-Stokes equations by Lei and Lin [11], holds under the effect of the Coriolis force. As an application existence of a unique global solution for arbitrary speed of rotation is proved, as well as its asymptotic behavior.
Myasthenia gravis in a professional cyclist—A case report  [PDF]
Hiroteru Hayashi, Hiroki Funasaki, Kentaro Kawai, Sakiko Ito, Keishi Marumo
Open Journal of Therapy and Rehabilitation (OJTR) , 2013, DOI: 10.4236/ojtr.2013.12002
Abstract: Since myasthenia gravis affects the muscular system, athletes suffering from the disease often have difficulty in performing or returning to their sports activity, in which exertion of continuous muscular power is required. In this paper, we present a case of a professional bicycle rider with symptomatic MG who successfully return to his sport activity after thymectomy, steroid pulse therapy and aggressive rehabilitation. He resumed load training, returned to competitive cycling 8 months after leaving hospital while being on 20 mg PSL/day, and won seven victories in the top class cycling competitions. This is the first report on a professional athlete suffering from MG who successfully returned to competitive sports after aggressive steroid treatment.
Lexicon Creation for Financial Sentiment Analysis Using Network Embedding  [PDF]
Ryo Ito, Kiyoshi Izumi, Hiroki Sakaji, Shintaro Suda
Journal of Mathematical Finance (JMF) , 2017, DOI: 10.4236/jmf.2017.74048
Abstract: In this study, we aim to construct a polarity dictionary specialized for the analysis of financial policies. Based on an idea that polarity words are likely located in the secondary proximity in the dependency network, we proposed an automatic dictionary construction method using secondary LINE (Large-scale Information Network Embedding) that is a network representation learning method to quantify relationship. The results suggested the possibility of constructing a dictionary using distributed representation by LINE. We also confirmed that a distributed representation with a property different from the distributed representation by the CBOW (Continuous Bag of Word) model was acquired and analyzed the differences between the distributed representation using LINE and the distributed representation using the CBOW model.
Parotid lymph node metastasis in a patient with tongue cancer  [PDF]
Kenji Yamagata, Naomi Ishibashi Kanno, Hiroyuki Ito, Shogo Hasegawa, Toru Yanagawa, Kojiro Onizawa, Hiroki Bukawa
Case Reports in Clinical Medicine (CRCM) , 2014, DOI: 10.4236/crcm.2014.31006

Parotid lymph node (LN) metastasis occurs most commonly from cutaneous squamous cell carcinoma (CSCC) of the head and neck, but rarely from oral squamous cell carcinoma (OSCC). Here, we present a rare case of metastasis to the parotid LN in a patient with tongue cancer. Although usual extent of modified radical neck dissection that includes resection of the tail of the parotid gland is below the line of the mandibular angle and the mastoid process was performed, the parotid LN metastasis occurred. The patient was treated with partial parotidectomy and chemoradiotherapy. One year and two months later, there was no evidence of local recurrence, although multiple lung metastases were observed. We also review the literature on parotid LN metastasis from OSCC.

Isoleucine, an Essential Amino Acid, Induces the Expression of Human β Defensin 2 through the Activation of the G-Protein Coupled Receptor-ERK Pathway in the Intestinal Epithelia  [PDF]
Youkou Konno, Toshifumi Ashida, Yuhei Inaba, Takahiro Ito, Hiroki Tanabe, Atsuo Maemoto, Tokiyoshi Ayabe, Yusuke Mizukami, Mikihiro Fujiya, Yutaka Kohgo
Food and Nutrition Sciences (FNS) , 2012, DOI: 10.4236/fns.2012.34077
Abstract: Anti-microbial peptides are essential for the intestinal innate immunity that protects the intestinal epithelia from attacks by foreign pathogens. Human β-defensin (HBD) is one of the pivotal anti-microbial peptides that are expressed in the colonic epithelia. This study investigated the effect and the signaling mechanism of inducible β-defensin HBD2 by an essential amino acid, isoleucine (Ile) in colonic epithelial cells. Here we examined the expression level of HBD2 on induction of Ile in epithelial cells, and checked this pathway. HBD2 mRNA was induced by co-incubation with IL-1α and Ile in Caco2 cells, but not by Ile alone. An inhibitor of either ERK or Gi, a subunit of G-proteins, reduced the induction of HBD2 mRNA by Ile. The treatment with Ile also increased the intracellular calcium ion concentration, thus suggesting that the GPCR and ERK signaling pathway mediate the effects of Ile. These results indicate that an essential amino acid, Ile, enhances the expression of an inducible β-defensin, namely HBD2, by IL-1α through the activation of GPCRs and ERK signaling pathway. The administration of Ile may therefore represent a possible option to safely treat intestinal inflammation.
Immobilization of His-Tagged Proteins on Various Solid Surfaces Using NTA-Modified Chitosan  [PDF]
Masahiko Oshige, Kazuhiro Yumoto, Hidefumi Miyata, Shunsuke Takahashi, Masaki Nakada, Kanako Ito, Miwa Tamegai, Hiroki Kawaura, Shinji Katsura
Open Journal of Polymer Chemistry (OJPChem) , 2013, DOI: 10.4236/ojpchem.2013.31002

Continued advancement of protein array, bioelectrode, and biosensor technologies will necessitate development of methods that allow for increased protein immobilization capacity and more control over protein orientation. Toward these ends, we developed a method involving modification of chitosan with nitrilotriacetic acid (NTA) to achieve immobilization of a larger amount of His-tagged protein than is possible with current methods. The immobilization capacity of our method was evaluated using His-tagged GFP (Green Fluorescent Protein) as a model protein. The average immobilization density on modified glass was about 32 ng/mm2. Our method is suitable for use on a variety of solid surfaces, including glassy carbon, silicon wafers, polycarbonate, and beaten gold.

C-reactive protein in patients with advanced metastatic renal cell carcinoma: Usefulness in identifying patients most likely to benefit from initial nephrectomy
Ito Hiroki,Shioi Koichi,Murakami Takayuki,Takizawa Akitoshi
BMC Cancer , 2012, DOI: 10.1186/1471-2407-12-337
Abstract: Objective C-reactive protein (CRP) is considered a useful serum marker for patients with RCC. However, its clinical utility in advanced metastatic renal cell carcinoma (AM-RCC), particularly in deciding whether to perform nephrectomy at the onset, is not well studied. Patients and methods We retrospectively evaluated 181 patients with AM-RCC, including 18 patients underwent potentially curative surgery, 111 underwent cytoreductive nephrectomy, and 52 received medical treatment only. CRP cutoff points were determined by receiver operating characteristic (ROC) curve analysis. Kaplan-Meier and Cox regression analyses were used for survival tests. Results ROC analysis suggested that grouping patients according to 3 CRP ranges was a rational model. Patients with highly elevated CRP (≥67.0 mg/L) presented remarkably poor prognosis despite treatment (nephrectomy or medical treatment only). Cox regression models demonstrated that risk factors of overall survival for patients who underwent nephrectomy were the CRP ranges defined in this study (≤18.0 mg/L, >18.0 and <67.0 mg/L, and ≥67.0 mg/L), ECOG PS (0, 1, and ≥2), and number of metastatic organ sites (0–1 and ≥2). The retrospective design is a limitation of this study. Conclusion Our study demonstrated that the serum CRP level is a statistically significant prognostic parameter for patients with AM-RCC. The data also indicated that pretreatment serum CRP level provides useful prognostic information that helps in deciding whether to perform initial nephrectomy for patients with AM-RCC.
Novel Magnetic and Thermodynamic Properties of Thiospinel Compound CuCrZrS$_{4}$
Masakazu Ito,Hiroki Yamamoto,Shoichi Nagata,Takashi Suzuki
Physics , 2005, DOI: 10.1103/PhysRevB.74.214412
Abstract: We have carried out dc magnetic susceptibility, magnetization and specific heat measurements on thiospinel CuCrZrS$_{4}$. Below $T_{\rm C}^{*} =$ 58 K, dc magnetic susceptibility and magnetization data show ferromagnetic behavior with a small spontaneous magnetization 0.27 $\mu_{\rm B}/$f. u.. In dc magnetic susceptibility, large and weak irreversibilities are observed below $T_{\rm f} =$ 6 K and in the range $T_{\rm f}< T < T_{\rm C}^{*}$ respectively. We found that there is no anomaly as a peak or step in the specific heat at $T_{\rm C}^{*}$.
Jet propagations, breakouts and photospheric emissions in collapsing massive progenitors of long duration gamma ray bursts
Hiroki Nagakura,Hirotaka Ito,Kenta Kiuchi,Shoichi Yamada
Physics , 2010, DOI: 10.1088/0004-637X/731/2/80
Abstract: We investigate by two-dimensional axisymmetric relativistic hydrodynamical simulations (1) jet propagations through an envelope of a rapidly rotating and collapsing massive star, which is supposed to be a progenitor of long duration gamma ray bursts (GRBs), (2) breakouts and subsequent expansions into stellar winds and (3) accompanying photospheric emissions. We find that if the envelope rotates uniformly almost at the mass shedding limit, its outer part stops contracting eventually when the centrifugal force becomes large enough. Then another shock wave is formed, propagates outwards and breaks out of the envelope into the stellar wind. Which breaks out earlier, the jet or the centrifugal bounce-induced shock, depends on the timing of jet injection. If the shock breakout occurs earlier owing to a later injection, the jet propagation and subsequent photospheric emissions are affected substantially. We pay particular attention to observational consequences of the difference in the timing of jet injection. We calculate optical depths to find the location of photospheres, extracting densities and temperatures at appropriate retarded times from the hydrodynamical data. We show that the luminosity and observed temperature of the photospheric emissions are both much lower than those reported in previous studies. Although luminosities are still high enough for GRBs, the observed temperature are lower than the energy at the spectral peak expected by the Yonetoku-relation. This may imply that energy exchanges between photons and matter are terminated deeper inside or some non-thermal processes are operating to boost photon energies.
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