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Search Results: 1 - 10 of 593902 matches for " Hilda A Pérez "
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La malaria por Plasmodium Vivax (Grassi y Feletti, 1890) en los trópicos y los retos de la cura radical
Pérez,Hilda A;
Interciencia , 2004,
Abstract: plasmodium vivax is the most widespread species causing human malaria; it prevails in asia, central and south america and the western pacific, and its global burden is of approximately 80 million cases annually. although rarely fatal, the parasite causes recurrent morbid epishowed a well tolerated regimen in adults. however, clinical data from several tropical countries indicate that for an unfailing radical cure of tropical infections a higher dose of pq should be given. it seems therefore, that clinical and epidemiological management of p. vivax malaria in the tropics is complicated by the wide spread of pq tolerant parasites producing short-term relapses in an ecological environment where transmission is favored. studies on the more appropriate therapeutic regimen of pq for radical cure of p. vivax in the tropics are required without delay.
Lymph node cell responsiveness in BALB/C mice infected with Leishmania mexicana
Pérez, Hilda A.;Bolívar, José;
Memórias do Instituto Oswaldo Cruz , 1985, DOI: 10.1590/S0074-02761985000200002
Abstract: in the present study we measured the blastogenic response of lymph node cells from balb/c mice infected with leishmania mexicana throughout the course of infection. results showed that infected mice displayed normal blastogenic responses in the lymph nodes until twenty weeks of infection. thereafter, there was a gradual suppression. comparison of the immunoresponsiveness in the spleen and lymph nodes, revealed normal responses in the lymph nodes several weeks after suppression in the spleen had occurred. suppression of blastogenic responses in the lymph nodes was related to an adherent macrophage-like cell which actively suppressed normal proliferative responses to mitogens.
Activación de celulas supresoras de la respuesta de hipersensibilidad tardía en ratones BALB/c infectados o vacunados con Leishmania mexicana pifanoi
Pérez, Hilda A.;Henriquez, Milagros;Rosa, Mercedes de la;
Memórias do Instituto Oswaldo Cruz , 1985, DOI: 10.1590/S0074-02761985000400008
Abstract: a t suppressor cell population that specifically shut down delayed hypersensitivity responses (dhr) to the parasite was found in both balb/c mice chronically infected with leishmania mexicana pifanoi and in naive mice which had received a single iv supraoptimal dose of killed parasites. at the early phase of infection mice exhibited a transitory state of cell-mediated immunity against the parasite that was abrogated when lesions reached their accelerated phase of growth. results suggest that in both infected and high-dose immunized mice, the activation of t suppressor cells of dhr is related to antigen overload.
Diagnosis of malaria by acridine orange fluorescent microscopy in an endemic area of Venezuela
Bosch, Irene;Bracho, Carmen;Pérez, Hilda A;
Memórias do Instituto Oswaldo Cruz , 1996, DOI: 10.1590/S0074-02761996000100014
Abstract: fluorescent (acridine orange) microscopical examination of capillary centrifuged blood (quantitative buffy coat [qbc?] analysis) and giemsa stained thick blood smears (gts) were compared for diagnosis of malaria in blood specimens from adults living in malaria transmission areas of the states of bolivar and amazonas in southeastern and south venezuela, respectively. of a total of 198 gts examined, 95 subjects (48%) showed parasitaemia. among the 95 blood films with a positive gts, 94 were judged positive by the qbc. however, positive qbc tubes were found in 29 out of 103 blood specimens with a negative gts. thus, relative to a gts standard, the sensitivity and specificity of the qbc-test was 99.2% and 72%, respectively. young trophozoites of plasmodium vivax and p. falciparum could not be distinguished with certainty. it is confirmed that the qbc offers many advantages compared with the standard diagnosis of malaria parasites, specifically in the speed of staining and ease of interpretation. however, in places where p. falciparum and p. vivax occur, species and stage differentiation should be confirmed with the gts.
El paludismo y las pruebas rápidas de diagnóstico
Pérez,Hilda A; Bracho,Carmen; De La Rosa,Mercedes;
Boletín de Malariología y Salud Ambiental , 2007,
Abstract: rapid tests for malaria diagnosis use basic principles of lateral flow immuno-chromatography to identify specific molecules secreted by the blood stages of malaria parasites. they are simple and rapid to execute without laboratory equipment, sensitive and friendly to use. the first generation identified plasmodium falciparum only. later on, those distinguishing between falciparum malaria and non-falciparum malaria were developed. antigenic targets more commonly used have been the histidine rich protein 2 of p. falciparum and the aldolase and lactate dehydrogenase enzymes of plasmodium sp. those criticizing rapid tests for malaria diagnosis refer to poor sensitivity mainly with low-density parasitaemias, false positive, false negatives along with their inability to diagnose mixed infections, to recognize plasmodium vivax and to quantify the parasitaemias. the performance of the abovementioned tests in endemic areas, the evolution of their prototypes, their reliability in the improvement of diagnosis, cost/benefit relation and potential problems with the interpretation of the tests after anti-malarial treatment are discussed in this review. successful application of malaria rapid diagnosis tests in endemic areas should focus on the evaluation of current and new devices in local settings and on the promotion and enhancement of training in technical skills for health workers in endemic countries.
Cuando el coito produce dolor: una exploración de la sexualidad femenina en el noroeste de México
García-Pérez,Hilda; Harlow,Sioban D;
Salud Pública de México , 2010, DOI: 10.1590/S0036-36342010000200007
Abstract: objective: to determine the prevalence of dyspareunia among women aged 25-54 and its associated risk factors. material and methods: a cross-sectional population-based study was carried out in the city of hermosillo, sonora and data from 1183 sexually active women were analyzed. a multiple logistic regression was computed to analyze the association between dyspareunia and sociodemographic characteristics, medical conditions and sexual violence. results: the 12-month prevalence of dyspareunia was estimated to be 12.3% (95% ci 10.5, 14.4). after adjustment for working conditions, dyspareunia was associated with younger ages (25-34 years), history of sexually transmitted diseases/pelvic inflammatory disease, chronic urinary tract infections, colitis and history of sexual violence. conclusion: increased attention to this condition by reproductive health programs and primary care services is urgently needed in mexico.
Evaluación de dos métodos colorimétricos para cuantificar sustancias pécticas en parchita (passiflora edulis) Evaluation of two colorimetric methods for quantification of pectic substances in passion fruit (Passiflora edulis)
Humberto Barazarte,Tonny García,Elba Garrido,Hilda Pérez
Bioagro , 2010,
Abstract: El análisis rutinario de pectinas en productos vegetales requiere de técnicas cuantitativas rápidas y precisas. Por tal motivo, se evaluó la exactitud y precisión de los métodos carbazol y m-hidroxifenilfenol en la cuantificación del contenido péctico en cáscara de parchita. Se determinó el porcentaje de recuperación de ácido galacturónico (AGA) y coeficiente de variación (CV) a muestras deshidratadas con adición de cantidades variables de pectina comercial y se cuantificó el contenido de AGA utilizando los métodos antes se alados. Con el método del carbazol se obtuvo recuperación de AGA de 90,74 a 102,18 % y coeficiente de variación (CV) de 0,80 a 3,44 %, mientras que con el método del m-hidroxifenilfenol la recuperación fue de 85,01 a 107,9 % de AGA y CV de 2,74 a 5,98 %, lo que refleja baja dispersión y poco efecto de sustancias interferentes. En cáscara de parchita se obtuvo de 15,81 a 17,0 % de AGA en base seca. De acuerdo con la sencillez, reproducibilidad y mínimo efecto de compuestos interferentes, se concluye que los métodos colorimétricos del carbazol y del m-hidroxifenilfenol son útiles en la determinación de sustancias pécticas en cáscara de frutos como la parchita. The routine analysis of pectins in vegetal products requires fast and precise quantitative techniques. By such a reason, the accuracy and precision of the carbazole and m-hydroxydiphenyl methods for quantification of pectin content in passion fruit rind was evaluated. The galacturonic acid (GA) recovery was determined in dehydrated samples with addition of varying amounts of commercial pectin, and the rind GA content was quantified using the mentioned methods. With the carbazole method, recovery from 90.74 to 102.18 % and coefficient of variation (CV) from 0.80 to 3.44 % was obtained, while with the m-hydroxydiphenyl method the recovery was from 85.01 to 107.9 % and CV from 2.74 to 5.98 %, reflecting low dispersion and little effect of interfering substances. In passion fruit rind from 15.81 to 17. 0 % of GA on a dry matter basis was obtained. Based on simplicity, reproducibility and minimal effect of interfering compounds, the carbazole and m-hydroxydiphenyl methods are useful for determination of pectic substances in fruits, like passion fruit.
Caracterización y potencialidades del grano de sorgo (Sorghum bicolor L. Moench) Characterization and potential of sorghum (Sorghum bicolor L. Moench) grain
A Pérez,O Saucedo,J Iglesias,Hilda B Wencomo
Pastos y Forrajes , 2010,
Abstract: El sorgo (Sorghum bicolor L. Moench) es uno de los cereales que por sus características agronómicas y nutricionales pudiera aportar grandes beneficios en la alimentación, tanto humana como animal, a nivel mundial, tropical y nacional. Este cultivo se adapta bien a las condiciones de Cuba, el cual mostró un incipiente desarrollo que desapareció de forma paralela a la colaboración del CAME (Consejo de Ayuda Mutua Económica). Hoy no existe una amplia tradición y experiencia en cuanto a su producción; sin embargo, diferentes ensayos indican que los rendimientos son satisfactorios y que pudieran incrementarse si se contara con tecnologías apropiadas y sustentables que permitieran expresar todo su potencial. En el presente artículo se exponen las características generales, botánicas y agronómicas del género y sus especies, así como sus potencialidades y usos, con el objetivo de actualizar el conocimiento como una contribución a dar soluciones a la actual crisis alimentaria que sufre el Planeta. Asimismo se incluyen algunos resultados obtenidos en la República de Cuba. Sorghum (Sorghum bicolor L. Moench) is one of the cereals that due to their agronomic and nutritional characteristics could contribute large benefits in human as well as animal feeding, at world, tropical and national level. This crop is well adapted to Cuban conditions, and showed an incipient development that disappeared parallel to the collaboration of COMECON (Council of Mutual Economic Assistance). Today no vast tradition and experience exist regarding its production; however, different essays indicate that the yields are satisfactory and that they could be increased if there were appropriate and sustainable technologies that allowed to express all its potential. In this article the general, botanical and agronomic characteristics of the genus and its species, as well as its potential and usages are presented with the objective of updating knowledge as a contribution to providing solutions for the current food crisis undergone by the Planet. Likewise, some results obtained in the Republic of Cuba are included.
Evaluación de dos métodos colorimétricos para cuantificar sustancias pécticas en parchita (passiflora edulis)
Barazarte,Humberto; García,Tonny; Garrido,Elba; Pérez,Hilda; Terán,Yanira;
Bioagro , 2010,
Abstract: the routine analysis of pectins in vegetal products requires fast and precise quantitative techniques. by such a reason, the accuracy and precision of the carbazole and m-hydroxydiphenyl methods for quantification of pectin content in passion fruit rind was evaluated. the galacturonic acid (ga) recovery was determined in dehydrated samples with addition of varying amounts of commercial pectin, and the rind ga content was quantified using the mentioned methods. with the carbazole method, recovery from 90.74 to 102.18 % and coefficient of variation (cv) from 0.80 to 3.44 % was obtained, while with the m-hydroxydiphenyl method the recovery was from 85.01 to 107.9 % and cv from 2.74 to 5.98 %, reflecting low dispersion and little effect of interfering substances. in passion fruit rind from 15.81 to 17. 0 % of ga on a dry matter basis was obtained. based on simplicity, reproducibility and minimal effect of interfering compounds, the carbazole and m-hydroxydiphenyl methods are useful for determination of pectic substances in fruits, like passion fruit.
DISMINUCIóN DE LAS PREVALENCIAS DE DESNUTRICIóN MEDIANTE LA PROMOCIóN DE LA SALUD EN GRUPOS DE ESCOLARES EN UNA LOCALIDAD DE BOGOTá
Pérez,Ruth; Hilda Aya,Dora; Prieto,Franklyn; Pinzón-Rondón,ángela María;
Revista U.D.C.A Actualidad & Divulgación Científica , 2012,
Abstract: malnutrition is prevalent in school aged children. it impairs the health and school performance of those affected in the short and in the long run. the objective of this study was to identify the changes in the prevalence of malnutrition in groups of school-aged children that were intervened by medical students with a strategy that combined educational activities, health evaluation, and actions directed to children with particular problems. this article presents the evaluation of the program "salud escolar integral" [comprehensive school health]. this program was conducted by medical students from universidad del rosario school of medicine and health sciences. an ecological study was done with measures before and after intervention. population: elementary school students from 5 to 8 years of age. acute, chronic, and global undernourishment were calculated. during the five years of monitoring an statistically significant decrease was found in the prevalence of acute malnutrition from 4.5 to 0.6%, global malnutrition from 11.8 to 5.8%, and chronic malnutrition from 16.4 to 8.3%. this study presents evidence on the effectiveness of a comprehensive interventional program developed by medical students to decrease undernourishment on school age children.
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