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Search Results: 1 - 10 of 167665 matches for " Hepgul E. Gulcin "
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Prevalence of Subclinical Hypothyroidism among Patients with Acute Myocardial Infarction
Okuyan Ertugrul,Uslu Ahmet,Enhos Asim,Hepgul E. Gulcin
ISRN Endocrinology , 2011, DOI: 10.5402/2011/810251
Abstract:
The Identification of Recurrent Laryngeal Nerve by Injection of Blue Dye into the Inferior Thyroid Artery in Elusive Locations
Gulcin Hepgul,Meltem Kucukyilmaz,Oguz Koc,Yigit Duzkoylu
Journal of Thyroid Research , 2013, DOI: 10.1155/2013/539274
Abstract:
The Identification of Recurrent Laryngeal Nerve by Injection of Blue Dye into the Inferior Thyroid Artery in Elusive Locations
Gulcin Hepgul,Meltem Kucukyilmaz,Oguz Koc,Yigit Duzkoylu,Yavuz Selim Sari,Yesim Erbil
Journal of Thyroid Research , 2013, DOI: 10.1155/2013/539274
Abstract: Introduction. Thyroidectomy creates a potential risk for all parathyroid glands and the recurrent laryngeal nerve (RLN). The identification and dissection of the RLN is the gold standard for preserving its function. In some cases, it may be quite difficult to identify the nerve localization. In such elusive locations, we aimed to identify RLNs using peroperative injection of a blue dye into the inferior thyroid artery. Materials and Methods. This study included 10 selected patients whose RLN identification had been difficult peroperatively during the period from April 2008 to June 2009. When the RLNs became elusive in location, the branches of the inferior thyroid artery (ITA) on the capsule of the thyroid lobe were isolated, and then 0.5?mL isosulphan blue dye was injected into the artery. Results. RLN was carefully dissected in the tracheoesophageal groove. RLN was clearly visualized, in all patients. All RLNs were identified along their course in the dyed surrounding tissue. No RLN palsy was encountered. Conclusion. The injection of blue dye into the ITA branches can be used as an alternate method in case of difficulty in identification of RLNs. 1. Introduction Thyroidectomy is one of the most frequent operations performed in iodine-deficient regions. The main postoperative complications are recurrent laryngeal nerve (RLN) palsy and hypoparathyroidism [1–3]. Although the overall incidence of nerve palsy is low, when it occurs, it becomes a devastating life-long handicap. The incidence of nerve palsy varies from 0% to 14%. Several factors influence the likelihood of injury to the nerve, including the underlying disease (substernal goiter, malignancy, Graves disease, etc.), the extent of resection, and the experience of the surgeon. The standard method for RLN preservation during thyroidectomy is routine visual identification of the nerve [1–3]. There are several approaches to identify the RLNs depending on the surgeon preference (distal or proximal to cricothyroid). But in some cases it may be still quite difficult to localize the RLNs, and in these situations, blue dye injection into the inferior thyroid artery or its branches may be useful to identify the RLN. To our best knowledge this is the first report of using peroperative injection of a blue dye into the inferior thyroid artery to identify the RLN. 2. Materials and Methods This study included 10 patients (8 women and 2 men) who were selected during the period from April 2008 to June 2009. The median age of the patients was 64 years (range 51–76 years). The indication for surgery was a large
The Effect of Beta-Aminopropionitrile and Prednisolone on the Prevention of Fibrosis in Alkali Esophageal Burns: An Experimental Study
Kurtulus Aciksari,Hakan Teoman Yanar,Gulcin Hepgul,Dogac Niyazi Ozucelik,Fatih Yanar,Orhan Agcaoglu,Mediha Eser,Gamze Tanriverdi,Hakan Topacoglu,Baris Murat Ayvaci,Halil Dogan,Kayihan Gunay,Cemalettin Ertekin,Ferudun Celikmen
Gastroenterology Research and Practice , 2013, DOI: 10.1155/2013/574260
Abstract: Objective. The aim of this study was to investigate the efficacy of beta-aminopropionitrile (BAPN) and prednisolone on the prevention of esophageal damage and stricture formation after caustic esophageal burn. Method. Twenty-eight rats were divided into four equal groups. In groups 1, 2, and 3, caustic esophageal burns were generated by applying NaOH to the 1.5?cm segment of the abdominal esophagus. Group 4 was for the sham. Normal saline to group 1, BAPN to group 2, and prednisolone to group 3 were administered intraperitoneally as a single daily dose. Results. Treatment with BAPN decreased the stenosis index (SI) and histopathologic damage score (HDS) seen in caustic esophageal burn rats. The SI in group 4 was significantly lower compared with groups 1, 2, and 3. Group 2 had the minimum SI value in corrosive burn groups. The differences related to SI between groups 1, 2, and 3 were not statistically significant. The HDS was significantly lower in group 4 compared with groups 1, 2, and 3. The HDS in group 2 was significantly lower compared with groups 1 and 3. Conclusion. This study demonstrated that BAPN was able to decrease the development of stenosis and tissue damage better than prednisolone. 1. Introduction Exposure to caustic ingestions continues to be a serious problem in underdeveloped countries [1–3]. The incidence of corrosive agent ingestion ranges from 1/5000 to 1/26000 in the United States [4, 5]. Seventy percent of caustic injuries are located in esophagus [6]. Damage to the esophagus and stomach by caustic agents depends on the type, concentration, and form of those caustic agents and the duration of exposure [4, 5]. Following ingestion, solid or granular caustics often injure the oropharynx and proximal esophagus while liquid alkali ingestions are characterized by more extensive esophageal and gastric injuries. Severe intentional alkali ingestion may cause deep penetration into surrounding tissues with resultant multisystem organ injuries, including ocular, esophageal, and gastric perforation and necrosis of abdominal and mediastinal structures [7]. Animal data have shown decreased stricture formation with drugs that affect collagen deposition, including interferon-alfa-2b, octreotide, beta-aminopropionitrile (BAPN), N-acetylcysteine, and D-penicillamine [7, 8]. Few studies have demonstrated lathyrogens affecting the collagen fibril diameters and reducing intra-abdominal adhesions, anastomosis, and strictures [9–11]. BAPN is a compound known to cause lathyrism, a neurological disease by inhibiting lysyl oxidase, the enzyme that
QFD based Information Technology Planning Approach for Collaborative Product Development
Gulcin Buyukozkan,Sezin Guleryuz
Lecture Notes in Engineering and Computer Science , 2012,
Abstract:
Modelling Collaborative Software Development Using Axiomatic Design Principles
Jbid Arsenyan,Gulcin Buyukozkan
IAENG International Journal of Computer Science , 2009,
Abstract:
Support Policies in Clusters: Prioritization of Support Needs by Cluster Members According to Cluster Life Cycle
Gulcin Sal?ngan
International Review of Management and Marketing , 2012,
Abstract: Economic development has always been a moving target. Both the national and local governments have been facing the challenge of implementing the effective and efficient economic policy and program in order to best utilize their limited resources. One of the recent approaches in this area is called cluster-based economic analysis and strategy development. This study reviews key literature and some of the cluster based economic policies adopted by different governments. Based on this review, it proposes “the cluster life cycle” as a determining factor to identify the support requirements of clusters. A survey, designed based on literature review of International Cluster support programs, was conducted with 30 participants from 3 clusters with different maturity stage. This paper discusses the results of this study conducted among the cluster members in Eski ehir- Bilecik-Kütahya Region in Turkey on the requirement of the support to foster the development of related clusters.
A family of Unna-Thost disease with one of them showing findings of epidermolytic keratoderma
Karadag Ayse,Simsek Gulcin
Indian Journal of Dermatology, Venereology and Leprology , 2010,
Abstract:
Reticular erythematous mucinosis syndrome with telangiectasias
Karadag Ayse,Simsek Gulcin
Indian Journal of Dermatology, Venereology and Leprology , 2010,
Abstract:
Multiple angiokeratomas on the breast
Karadag Ayse,Simsek Gulcin
Indian Journal of Dermatology, Venereology and Leprology , 2009,
Abstract:
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