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Search Results: 1 - 10 of 4725 matches for " Hentova-Sen?ani? Paraskeva "
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Comparison of normotensive and glaucoma simplex patients according to age and sex
Stoj?i? Milan,Hentova-SenaniParaskeva,Stoj?i? Biljana,Senani? Ivan
Srpski Arhiv za Celokupno Lekarstvo , 2012, DOI: 10.2298/sarh1212699s
Abstract: Introduction. According to the level of intraocular pressure (IOP), open angle glaucoma is divided into high tension glaucoma (HTG) and normal tension glaucoma (NTG). Objective. To determine if there are differences in the distribution of patients by age and sex between NTG and HTG. Methods. Our prospective study included 30 patients with NTG and 30 with HTG. A complete eye examination was performed. The examination included measuring of intraocular pressure by Goldmann applanation tonometry, examination of optic disc head by indirect ophthalmoscopy with Volk 90 D lens and visual field examination using the Octopus program. Results. The average damage of visual field in the group of patients with NTG was 8.14±4.43 dB, while in the group with HTG it was 7.40±2.84 dB (p>0.05). The average age of the group of patients with NTG was 66±11.58 years, while among those with HTG the average age was 59.7±11.63 years (p<0.01). Among the patients with NTG there were three times more women than men (χ2=9.124; p<0.01), while in the group of patients with HTG there were more men than women, but without statistically significant difference between the tested groups (χ2=1.851; p>0.05). Conclusion. Open angle glaucoma is a disease of elderly population. According to our results, risk factors for this disease can be age and sex. NTG is more frequently present than HTG among elderly population and females.
Influence of initial visual field sensitivity on visual field loss progression in open angle glaucoma
Hentova-SenaniParaskeva,Bo?i? Marija,Senani? Ivan,Jovanovi? Milo?
Srpski Arhiv za Celokupno Lekarstvo , 2012, DOI: 10.2298/sarh1204142h
Abstract: Introduction. It is important to know the risk factors for visual field defect progression in order to predict the future development of glaucoma. Objective. To investigate the influence of visual field initial sensitivity on the rate of visual field progression. Methods. A minimum of five visual fields were performed using computerized perimetry (Octopus) over a mean follow- up 4-year period (48.85±17.84 months) in 64 persons (114 eyes) with primary open angle glaucoma. The rate of change of the whole central visual field and each of the seven regions of the field were measured by linear regression analysis of the mean sensitivity value versus time. Based on the slope of the regression line of visual field mean sensitivity over time the eyes were divided into two groups: the group with stable and the group with progressive visual field. The comparison of the mean sensitivity of the whole central visual field between the groups was performed using the Mann-Whitney U-test. The Spearman rang correlation coefficient and the Spearman probability p values were calculated to assess the mean sensitivity of the whole central visual field and of each visual field regions determined at the beginning of the study. Results. The initial mean sensitivity of the whole central visual field was lower in the group with progressive visual field (16.62±6.35 dB). Correlation between the initial mean sensitivity and the slope of the regression line was negative. The lowest mean sensitivity was in the group with progressive visual field in the upper temporal (13.73±7.35 dB), nasal (14.74±7.23 dB) and upper nasal (15.03±7.75 dB) regions. Conclusion. The lower mean sensitivity value of the visual field, especially in the nasal and upper nasal visual field regions, carries a greater risk for delayed progressive loss of the visual field in persons with glaucoma.
Differences of optic disc appearance between normal tension and high tension glaucoma patients
Stoj?i? Milan,Hentova-SenaniParaskeva,Stoj?i? Biljana
Srpski Arhiv za Celokupno Lekarstvo , 2011, DOI: 10.2298/sarh1108428s
Abstract: Introduction. The term glaucoma is used to cover a wide range of diseases, whose main feature is optic neuropathy. According to the level of intraocular pressure (IOP), the open angle glaucoma is arbitrarily divided into high tension glaucoma (HTG) and normal tension glaucoma (NTG). Objective. The aim of this study was to investigate the differences of optic disc cup appearance between patients with NTG and HTG. Methods. Prospective study included 30 patients (60 eyes) with NTG and 30 patients (60 eyes) with HTG. IOP was measured by Goldmann applanation tonometry. Examination of optic disc head was performed by indirect ophthalmoscopy with Volk 90 D superfield lens through a dilated pupil to observe qualitative and quantitative parameters. Visual fields were examined in all patients with the Octopus program G1, full threshold strategy (Octopus 500 EZ, Interzeag, Switzerland). Results. Vertical form of optic disc cup was present in 11 eyes with NTG (18.3%) and three eyes with HTG (5%) (p<0.05). A disc with localized tissue loss (polar notching) on the inferior pole was observed in eight eyes with NTG (13.3%) and in one eye with HTG (1.7%) (p<0.01). Uniformly enlarged, round cup was more frequent in patients with HTG than NTG: 93.3% and 68.3% respectively (p<0.05). Conclusion. The perceived differences indicate a complex multifactorial nature of glaucoma disease and a possible existence of two pathophysiological ways of optic disc changes within the same basic disease.
Prevention of intraocular pressure elevation after argon laser trabeculoplasty in primary open angle glaucoma
Bo?i? Marija,Hentova-SenaniParaskeva,Konti? ?or?e,Markovi? Vujica
Srpski Arhiv za Celokupno Lekarstvo , 2011, DOI: 10.2298/sarh1102012b
Abstract: Introduction. Argon laser trabeculoplasty (ALT) is an intraocular pressure lowering method that is overall safe and powerful, but often complicated by transient postoperative intraocular pressure rises. In prevention of this complication, we frequently use two potent alpha-adrenergic agonists - brimonidine and apraclonidine. Objective. The aim of this study was to compare brimonidine 0.2% and apraclonidine 0.5% efficacy and safety in prevention of intraocular pressure elevation after ALT. Methods. This was a prospective, randomized, double-masked and comparative study. This study included 27 POAG patients, 15 received 0.2% brimonidine, and 12 received 0.5% apraclonidine before laser surgery (22 eyes in both groups). Intraocular pressure readings were taken 1, 2, 3, 24 hours and 7 days after ALT. Student’s t-test was used to analyze data between two groups, and χ2 test to compare data within groups. Value p less than 0.05 was considered statistically significant. Results. We found statistically significantly lower IOP in eyes that received 0.2% brimonidine at readings taken 1 hour after ALT (p=0.001). There were no statistically significant differences in other IOP readings between two groups. Conclusion. A single preoperative drop of brimonidine 0.2% had similar efficacy and safety as apraclonidine 0.5% in preventing transient IOP elevations after ALT.
Correlation between central corneal thickness and intraocular pressure in various age groups
Marjanovi? Ivan,Konti? ?or?e,Hentova-SenaniParaskeva,Markovi? Vujica
Srpski Arhiv za Celokupno Lekarstvo , 2010, DOI: 10.2298/sarh1006279m
Abstract: Introduction The Pascal Dynamic Contour Tonometer (DCT) is an ophthalmic investigational device which directly calculates the dynamic pulsatile fluctuations in intraocular pressure (IOP) using a piezoelectric pressure sensor embedded in the devices tip. Objective The aim of this study was to compare IOP results obtained with Goldmann applanation tonometer (GAT), and their correlation with central corneal thickness (CCT) in patients of various age groups. Methods We studied 37 patients (17 male and 20 female), divided into three age groups: younger than 40 years; 40-60 years old, and older than 60 years. In the first and second group there were patients rarely and in the third mostly diagnosed and medicamentously compensated glaucoma. In topical anesthesia, first we measured CCT, with ultrasound pachimeter, then IOP with DCT and GAT. Results Statistically significant difference between measurements of IOP with the DCT and GAT appeared in all groups: I mean diff. -1.71 }1.27 mm; p<0.0001; II mean diff. -1.19 }1.06 mm; p<0.0001; III mean diff. -1.69 }1.67 mm; p<0.0001. CCT was in indirect correlation with the values of IOP measured both with the DCT and GAT in the first and third, while it was in the direct correlation with these values in the second group. Conclusion CCT had no influence on IOP measurements both with the DCT and GAT in none of the groups. The DCT cannot replace GAT, but it is a reliable device for the measurement of IOP particularly in corneal deformations (keratoconus, after corneal refractive surgery, corneal scars, etc.). .
Unilatelaral iris plateau syndrome after the use of ecstasy
Jovanovi? Predrag,Hentova-SenaniParaskeva,?ori? Lep?a,Petrovi? Maja
Vojnosanitetski Pregled , 2009, DOI: 10.2298/vsp0906487j
Abstract: Bacground. Courmon street name for 3,4-Methylenedioxymethamphetamine (MDMA) is ecstasy. This widely abused 'recreational' drug causes both an increased release of monoamine neurotransmitters, including serotonine and dopamine, and an increased reuptake inhibition of serotonin. As a consequence, mydriasis and increased intraocular pressure (IOP) in predisposed patients occur. We present herein a rare case of acute increased IOP after use of ecstasy. Case report. A female patient, aged 38 years, visited doctor complaing of a decreased vision acuity and severe pain in the left eye and in the left part of the head. The initial treatment was urgent antiglaucomatous therapy followed by withdrawal of subjective problems of the patient and improvement of objective finding. History taking procedure reveled that just before the onset of the pain the patient had used ecstasy and had had similar 'experience' 6 years ago after cocaine snorting. She had not been to a doctor although she had experienced sporadic migrenous pain. Previous medical records excavation of revealed optic disk (cup-to-dise C/D=06), Bjerum arcuate scotoma and iris plateau with narrow chamber angle (Scheie II- III) so the diagnosis was a rare unilateral iris plateau syndrome of the left eye. Although the patient was given some pieces of information about the dangerous and possible deadly consequences of psychoactive substance abuse, she has not continue the treatment. Conclusion. Ecstasy abuse might cause a complete loss of vision, thus medicametous and surgical treatment are obligatory.
Contribution and significance of Heidelberg retinal tomography II in diagnostics of ocular hypertension and its conversion into primary open-angle glaucoma
Markovi? Vujica,Konti? ?or?e,Hentova-SenaniParaskeva,Bo?i? Marija
Vojnosanitetski Pregled , 2009, DOI: 10.2298/vsp0904283m
Abstract: Background/Aim. A term 'ocular hypertension' is used when IOP is found to be > 21 mmHg on two consecutive occasions, in the absence of detectable glaucomatous damage. The aim of this study was to determine the significance and contribution of Heidelberg Retinal Tomography II (HRT II) results that show very early, subtle changes in retinal neurofibre layers (RNFL) in the optic nerve head that are specific for glaucoma itself (the loss of neuroretinal rim area and an increase of Cup/Disc ratio), but are not possible to register by an ophthalmoscope. Also, when the results of the functional tests remain unchanged, that confirms the conversion of ocular hypertension into glaucoma. Methods. During a 5-year study period (2002-2007), 29 patients with ocular hypertension were examined. The frequency of control examinations, based on the presence of risk factors for glaucoma development, was 3-6 months. The examination also included IOP measurements with Goldmann Applanation Tonometry (GAT), central corneal thickness (CCT) determination by pachymetry, the examination of chamber angle using indirect gonioscopy, visual field tests by computerized perimetry and also papillae nervi optici (PNO) examination by using HRT II. The application of HRT II enables a great number of stereometric parameters of optic disc, the most important being the rim area and Cup/Disc (C/D) ratio, which was followed during the control examination by each segment, as well as PNO in global. Results. In the examination period, three cases of conversion of ocular hypertension into a primary open-angle glaucoma were found. In the group of patients with ocular hypertension, HRT II results after six months did not show a significant increase in C/D ratio. No significant loss of rim area or rim volume was found either. In three cases of conversion, HRT II results after 3 months showed an increase of C/D ratio and also a significant loss in rim volume at first examination (0.413) comparing to the last one. Conclusion. In diagnosing ocular hypertension and its conversion to glaucoma, HRT II is used for quantitative evaluation of retinal topography and for quantitative monitoring of topographical changes, especially regarding the increase of C/D ratio and loss of rim volume tissue, which enables to see and register subtle structural changes in optic nerve head and RNFL that are so characteristic for glaucoma, which cannot be seen by an ophthalmoscope. With these results, according to risk factors for glaucoma, one can confirm the diagnosis of ocular hypertension and its conversion to primary open-an
The effect of intraocular pressure on visual field after trabeculectomy in patients with primary open angle glaucoma
Hentova-SenaniParaskeva P.,Bo?i? Marija M.,Senani? Ivan M.,Stoj?i? Milan M.
Acta Chirurgica Iugoslavica , 2012, DOI: 10.2298/aci1201061h
Abstract: Purpose: To compare the mean intraocular pres-sure (IOP), peak IOP and percentage reduction in IOP in the first live years following trabeculectomy between the patients with progressed visual field loss and the patients with stable visual fields. Material and methods: Thirty-six eyes of 36 patients were followed for five years after their first trabeculectomy with tonometry and automated perimetry (Octopus 500EZ, program Gl). The rate of change of the visual field was measured by linear regression analysis of the mean sensitivity value (dB9) of each field test versus time (month). Based on the statistical significance of the slope of the regression line (Spear man p value of the correlation coefficient less than 0.05), patients were divided into two groups: with significant negative slope of the regression line (group with progressed visual field loss) and with non-significant slope of the regression line (group with stable visual field). The mean IOP values and percentage of IOP reduction at the end of each of the first live years after surgery were compared between the group with progressed field loss and group with stable fields by using Mann-Whitney U test. Results: Patients with progressed visual field loss had higher mean IOP, higher peak IOP and less reduction in pressure after the operation than patients with stable visual field. The mean IOP at end of the two year postoperative period was significantly higher in patients with progressed visual field loss (21.98±3.38mmHg) than in those with stable fields (17.48±4,80mmHg). The mean percentage reduction in IOP at the end of two year postoperative peri-od was significantly less in patients that showed progression of field loss (21.84%) than in those with stable fields (41.0%). Conclusion: Prognosis for further field loss seems to be better if postoperative pressure is at lower levels and greater percent reduction of IOP is obtained after surgery. The data that predict better prognosis is the mean postoperative IOP value of approximately 18mmHg or less resulting from at least 35% of IOP reduction.
Effect of a tight necktie on intraocular pressure
Bo?i? Marija,Hentova-Sen?anin Paraskeva,Brankovi? Aleksandra,Marjanovi? Ivan
Medicinski Pregled , 2012, DOI: 10.2298/mpns1202013b
Abstract: Introduction. Any factor causing constriction of the neck may lead to an increase in intraocular pressure. A tight necktie may result in increasing intraocular pressure, which could lead to an erroneous diagnosis and treatment of ocular hypertension or even glaucoma. This study was aimed at evaluating the effect of a tight necktie on intraocular pressure measurement using Goldmann applanation tonometry. Material and Methods. This study included forty eyes of 20 patients with primary open angle glaucoma and 20 healthy controls (all male). Intraocular pressure was measured without a necktie, 3 minutes after placing a tight necktie and 3 minutes after loosening it. Student’s t-test was used to analyze the data between two groups. The intraocular pressure measurements were subjected to paired t - test. The value p < 0.05 was considered statistically significant. A possible correlation between the age of subjects and intraocular pressure values was analyzed using linear regression (Pearson′). Results. A statistically significant difference was found in intraocular pressure readings in all three measurements between two tested groups (p<0.05). When analyzed within groups, statistical significance in intraocular pressure readings was found after loosening the necktie (<0.05). No correlation between the age of subjects and increased intraocular pressure was found in either tested group of subjects after the necktie had been tightened (r2=0.006, p=0.70 for primary open angle patients, r2=0.07, p=0.22 for healthy controls). Conclusion. Wearing a tight necktie for a limited period of time during the day could be considered as a possible risk factor for glaucoma development.
Endoscopic Palliation for Unresectable Adenocarcinoma of the Pancreas
. Paraskeva K.
Annals of Gastroenterology , 2007,
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