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Search Results: 1 - 10 of 2025 matches for " Henrik Stoevring "
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Effect of a System-Oriented Intervention on Compliance Problems in Schizophrenia: A Pragmatic Controlled Trial
Hanne Skarsholm,Henrik Stoevring,Bent Nielsen
Schizophrenia Research and Treatment , 2014, DOI: 10.1155/2014/789403
Abstract: Background. Numerous studies have been conducted with a view to developing strategies for improvement of medical compliance in patients with schizophrenia. All of the studies conducted so far have had an individual approach to compliance based on the assumption that noncompliance is determined individually due to inappropriate behavior in the patient. We conducted a pragmatic controlled trial with a system-oriented approach, to provide a new perspective on compliance and test the efficacy of a multifactorial intervention at the system level in a routine clinical setting, an approach that has not previously been used for the improvement of compliance. Methods. 30 patients were allocated to the system-oriented therapy and 40 patients were allocated to the reference intervention, which consisted of individually based compliance therapy. The follow-up period was six months. Primary endpoint was improvement in compliance, measured by improvement in a compliance scale specifically developed for the project. Results. When accounting for missing values with a multiple imputation approach, we found a tendency toward a difference in both the compliance scale and PANSS favoring the system-oriented therapy, although it did not reach statistical significance. A significant difference in incidence of adverse events and time to first readmission was found. Attrition rates were significantly higher in the reference group and nonsignificant among individuals with lower compliance, which may have diluted effect estimates. This was reflected by significant differences found in an analysis based on a last observation carried forward approach. Conclusion. This study suggests that compliance problems are better solved by a multifactorial intervention at the system level than at the individual level. 1. Background Schizophrenia is a severe mental illness [1], for which the cornerstone of treatment is antipsychotic medication [2]. Compliance with the medications is poor, as only approximately 50% of the prescribed medication is consumed [3], even though a compromised compliance has extensive clinical and economic consequences [4, 5]. Consequently, numerous studies have been conducted to develop strategies for the improvement of compliance in schizophrenia [6–18]. These studies have all had an individual approach to compliance based on the assumption that noncompliance is individually determined and due to inappropriate behavior of the patient. Alternatively noncompliance could be regarded as an “incident” caused by a “system failure” [19], that is, a product of failed
Extending the Extensional Lambda Calculus with Surjective Pairing is Conservative
Kristian Stoevring
Mathematics , 2006, DOI: 10.2168/LMCS-2(2:1)2006
Abstract: We answer Klop and de Vrijer's question whether adding surjective-pairing axioms to the extensional lambda calculus yields a conservative extension. The answer is positive. As a byproduct we obtain a "syntactic" proof that the extensional lambda calculus with surjective pairing is consistent.
"Integrated Design Process" a Concept for Green Energy Engineering  [PDF]
Christian Koch, Henrik Buhl
Engineering (ENG) , 2013, DOI: 10.4236/eng.2013.53039
Abstract:

Consulting Engineers and Architects are currently experimenting with the concept of “Integrated Design Process” (IDP). This paper views Integrated Design Process as a process tool and a concept for management and organization of the green energy engineering process. Moreover such a concept is understood both as systematic knowledge and a symbolic device for enabling change. The paper briefly review international variants, and focus on two variants present in Denmark: an architect and engineering variant of IDP. The differences between the concepts include different roles for main actors, the use of information technology, the relation to lean, and forms of collaboration. The paper discusses two building projects focusing on teams of engineers and architects in the early conceptual phase. One develops a solution focused on energy saving technologies, the other on energy producing. It is argued that in this practical context, IDP is viewed as ambiguous and not well defined, and the architects and engineer work hard understanding and using the concepts even when directly involved. It is difficult to reach consensus on how to do it. The various players agree that an increased interdisciplinary interaction in the design team is necessary in order to comply with the increased complexity of green energy building design. IDP shows potential as a driver for green energy engineering and technologies, as traditional roles and responsibilities in the design process is changed, and sustainable solutions for green buildings can reach a higher standard and quality and are integrated earlier in the design process.

Distribution of Solar Irradiance on Inclined Surfaces Due to the Plane of the Ground  [PDF]
Teolan Tomson, Henrik Voll
Journal of Power and Energy Engineering (JPEE) , 2014, DOI: 10.4236/jpee.2014.27001
Abstract:

Measurements of solar radiation are ordinarily made on horizontal planes recording global, diffuse and reflected components. The beam component and distribution of the global radiation on tilted planes can be calculated via the said components, as the position of the Sun in the sky’s sphere is known. Another ordinary procedure is measuring beam and diffuse components and calculating global radiation. These measurements require stationary equipment and in such a way it is difficult to study the influence of different grounds on the distribution of radiation on the inclined surfaces due to the ground. This distribution has some importance in civil engineering, but it is not popular in the field of solar radiation investigations. Present paper shows how this distribution can be calculated measuring only global irradiance on the horizontal and vertical planes. Such an approach, which is valid in clear-sky and overcast conditions, allows the use of a portable measuring device and studies of different grounds. The coincidence of the calculated values with the actual is good, except for snow-cover and discrete cloud, which do not correspond to the isotropic sky and ground models.

Achieving Ecological Objectives
Henrik Josefsson
Laws , 2012, DOI: 10.3390/laws1010039
Abstract: The legal objective for surface water in the EU is ‘good ecological status’, as established by the Water Framework Directive, with a timeframe of 15, 21 or 27 years. To reach this objective, suitable legal instruments are needed, and quality standards are among the instruments intended to improve the ecological status. However, both the Directive and quality standards are founded on reductionism, risking an over-application of over-simplified concepts, probably reducing biological diversity. A realistic and more appropriate timeframe for river basin rehabilitation would be around 100 years, emphasizing several concerns, such as the importance of encompassing the entire life history of species, the shift in human perceptions, the systemic unity of humans and ecosystems, environmental irreducibility, site-specific reference points, and the divergence of the assessment of water quality and the general ecological status of a river basin. From a legal standpoint, a century emphasizes a temporal agreement and a normative commitment to the generations to come. Ecologically, a century time-scale gives enough time for the processes of evolution, dispersal and recolonization and succession to re-establish stable, more diverse biological communities in physically rehabilitated habitats and river basins, whereas the present timetable for achievement of the ecological objectives does not.
Methylenetetrahydrofolate reductase and transcobalamin genetic polymorphisms in human spontaneous abortion: biological and clinical implications
Henrik Zetterberg
Reproductive Biology and Endocrinology , 2004, DOI: 10.1186/1477-7827-2-7
Abstract: Accumulating evidence suggest that the sulfur-containing amino acid homocysteine plays a role in various developmental disorders [1]. Two main factors affect homocysteine concentration in humans: diet (mainly intake of folate and vitamin B12) and polymorphisms in genes that encode enzymes or transport proteins involved in folate- and vitamin B12-dependent homocysteine metabolism, the so called one-carbon metabolism, which is a complex series of metabolic pathways crucial for DNA synthesis and repair and a wide range of methylation reactions (Fig. 1).Methylenetetrahydrofolate reductase (MTHFR, EC 1.5.1.20) is a key enzyme in one-carbon metabolism. The enzyme catalyzes the conversion of 5,10-methylenetetrahydrofolate into 5-methyltetrahydrofolate, the predominating circulating form of folate. 5-methyltetrahydrofolate participates in the vitamin B12-dependent remethylation of homocysteine to methionine that is converted to S-adenosylmethionine that serves as a methyl group donor in the methylation of DNA, proteins, neurotransmitters and phospholipids [2]. MTHFR gene polymorphisms are commonly associated with hyperhomocysteinemia [3,4]. In pregnant women this is a risk factor for neural tube defects (NTD) [5,6] and recurrent embryo loss [7-9] as discussed thoroughly in three recent reviews [10-12]. Recently, Gris et al. also reported an association between increased levels of homocysteine and a first early pregnancy loss [13]. The best characterized MTHFR genetic polymorphism consists of a 677C>T transition which results in an alanine to valine substitution in the predicted catalytic domain of MTHFR [3]. This substitution renders the enzyme thermolabile, and homozygotes and heterozygotes have about a 70% and 35% reduced MTHFR activity in vitro, respectively. Homozygosity for the 677T allele is associated with elevated homocysteine levels, predominantly in individuals who have a low plasma folate level [14]. Furthermore, the level of plasma homocysteine can be lowered in
Causes and consequences of song amplitude adjustment in a territorial bird: a case study in nightingales
Brumm, Henrik;
Anais da Academia Brasileira de Ciências , 2004, DOI: 10.1590/S0001-37652004000200017
Abstract: vocal amplitude, one of the crucial factors for the exchange of acoustic signals, has been neglected in studies of animal communication, but recent studies on song variation in common nightingales luscinia megarhynchos have revealed new insights into its importance in the singing behavior of territorial birds. in nightingales song amplitude is not maximized per se, but is individually regulated according to the level of masking background noise. also, birds adjust their vocal intensity according to social variables, as in male-male interactions. moreover, during such interactions, males exploited the directionality of their songs to broadcast them in the direction of the intended receivers ensuring the most effective signal transmission. studies of the development of this typical long-range signaling suggest that sound level is highly interrelated with overall developmental progression and learning, and thus should be viewed as an integral part of song ontogeny. i conclude that song amplitude is a dynamic feature of the avian signal system, which is individually regulated according to the ecological demands of signal transmission and the social context of communication.
Discourse ethics in TA procedures: a game theory model
Henrik Pontzen
Poiesis & Praxis , 2006, DOI: 10.1007/s10202-006-0024-5
Abstract: Eine Ethik in TA-Verfahren ist nur als Risikoethik m glich, da die Folgen technischen Handelns ambivalent und unsicher sind. Der Artikel unterscheidet zun chst m gliche Rechtfertigungsstrategien für eine Risikoethik, n mlich (a) deontologische (b) teleologische und (c) prozedurale Ans tze. Nach einer kurzen Kritik von (a) und (b) arbeitet der Artikel durch spieltheoretische Modellierung ein zentrales Problem für die Einbindung der Diskursethik in TA-Verfahren heraus: durch Selbstselektionsmechanismen wird die Repr sentativit t von Diskursen unterh hlt und somit ihre Legitimation unterminiert. Deshalb wird vorgeschlagen, die zueinander komplement ren Ans tze (a)–(c) in eine provisorischen Moral” selektiv zu integrieren.
Legal Deposit in Denmark - the New Law and Electronic Products
Henrik Dupont
Liber Quarterly : The Journal of European Research Libraries , 1999,
Abstract: In 1997 Denmark celebrated the tricententenary of its legal deposit legislation and at the same time created a new law that surpassed the former 1927 text, which was out of date due to technological and political developments. In the first law on legal deposit, maps were not mentioned explicitly and we have no known examples of maps delivered before a revision of the law in 1781, which explicitly stated that maps and prints had to be deposited. It was only after 1850 that it became possible to follow what was deposited exactly. The number of maps deposited before was limited, not even including the first national survey maps. Maps were only produced in a limited number and the annual deposit did not exceed 600. We assume that all in all some 40,000 maps have been delivered to the collections by legal deposit. Each year since the Second World War the maps have been listed in the annual Dansk Kortfortegnelse” and since 1980 all new maps have been catalogued in the REX database of the Royal Library.
The palm book
Henrik Balslev
Frontiers of Biogeography , 2011,
Abstract:
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