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Search Results: 1 - 10 of 1496 matches for " Helicobacter pylori "
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Sabía usted? Infección por helicobacter pylori
Federico Díaz González
Iatreia , 1993,
Abstract:
Immunological and morphological aspects of diagnostics of Helicobacter pylori infection and Herpesviridae viruses
N.G. Dudaeva,V.B. Grechushnikov,I.O. Bugaeva,G.N. Tarasova
Saratov Journal of Medical Scientific Research , 2010,
Abstract: 100 patients with inflammatory diseases of gastrointestinal tract were examined. Microbial component of inflammation process was detected by means of polymerase chain reaction (PCR). By means of PCR etiological microbial factor of mononuclear cells in peripheral blood (MCPB) was investigated. Mixtinfication of mucosa membrane of gastrointestinal tract with H. pylori and Herpesviridae in pathology of gastroduodenal area and presence of fragments of microorganisms DNA in PBMC were revealed. This phenomenon may be important in pathogenesis of pathology of gastrointestinal tract and forms the basis for its further investigation
FREKUENSI POSITIVITAS ANTIBODI TERHADAP HELICOBACTER PYLORI PADA KELOMPOK DONOR DARAH DI SURAKARTA
J. B. Suparyatmo
Bulletin of Health Research , 2012,
Abstract: The patho-physiology of the gastritis achieved a significant progress in 1983, when it was proven that Helicobacter pylori colonized in the gastric mucosa. Several studies confirmed the relationship between Helicobacter pylori (H. pylori) and the type B gastritis. Further study reported the evidence of H. pylori colonization in the gastric anthrum of almost all duodenal ulcer patients. Since this micro-organism infected almost all subjects through out all ages, epidemiological data was therefore very important to determine the strategy to control the disease. This study aims to obtain the prevalence of the positivity of the antibody against. H. pylori (anti-Hp) among the volunteer blood donors in Surakarta. The passive haemagglutination (PHA) method (Biomedik-Mataram) was carried out to test the anti-Hp among 511 healthy subjects. The results obtained were 1984 (36%) showed anti-Hp positive. There is no significant difference between male and female groups in this study (p>0.05). The results of this study can be used as a preliminary study for further research to complete the epidemiological data of the H. pylori infectivity in Surakarta.
Peptic Ulcer Disease in CHUYO  [PDF]
A. Coulibaly, A. K. Sermé, H. Godonou, K. S. Somda, K. Cissé, Sia Romond, Kafando Roch, R. A. Sombié, A. Bougouma
Open Journal of Gastroenterology (OJGas) , 2016, DOI: 10.4236/ojgas.2016.611038
Abstract: Background: Prevalence of Peptic Ulcer Disease (PUD) is decreasing in developed countries since the use of the treatments for eradication of Helicobacter pylori. Objectives: To revalue the sociodemographic, clinical and evolutionary aspects of the PUD among hospitalized patients in CHUYO. Methodology: This prospective study is related to 65 files of patients hospitalized in hepato-gastroenterology and general surgical services of the CHUYO between March 1st and August 31st, 2015. Results: Hospital utilization rate was 6.59%. The average age of patients was 40.6 years with extremes of 17 and 80 years. The sex ratio was 9.8. The location of the ulcer was 69.23% in stomach. A notion of taking aggressive gastrointestinal products was found in 62 patients (95.4%). The clinical picture was represented by diffuse abdominal pain (76.92%), peritoneal irritation syndrome (64.61%) and epigastric pain (56.92%), anemia (23.07%). Gastric perforations (64.61%) and gastrointestinal bleeding (12.30%) were the main complications. Consumption of non-steroidal anti-inflammatory drugs (NSAIDs) was found in 81.5% of cases. The management was medical and/or surgical with an overall mortality rate of 7.7%. Conclusion: The PUD rate decreased from 10.12% to 6.59% in 5 years. The complications are dominated by stomach perforations. They are relative increase and seem related to NSAIDs. Better management of this disease requires awareness of the population to self-medication.
Relationship between the Level of Helicobacter pylori and Number of Platelets in Non-ITP Patients Who Underwent Gastroscopy  [PDF]
Osman Mavis, Korhan Kapucu
Open Journal of Gastroenterology (OJGas) , 2017, DOI: 10.4236/ojgas.2017.75018
Abstract: Purpose: To investigate both the presence of H. pylori in non-ITP patients who had not undergone H. pylori eradication, and also its relationship (if any) with the number of platelets. Methods: This retrospective study was performed with a total of 220 cases aged between 18 and 65 years who had undergone gastroscopy. H. pylori levels of the participants were investigated, and concurrently their hemograms were analyzed, and their platelet counts were performed. At the same time, cases in the H. pylori positive arm were compared with sub-groups categorized based on their degree of positivity. Results: A statistically significant difference was not detected between platelet counts of the cases based on their H. pylori levels (p = 0.583). A statistically significant difference was detected between H. pylori levels, and distribution of histopathological diagnosis of the cases (p = 0.001; p < 0.01). Conclusion: Our study results revealed that in cases where any primary or secondary factor which might affect platelets is absent, the presence of H. pylori has not any effect on platelet counts.
Tratamiento de la infección por Helicobacter pylori: Comentario al respecto
Noel Padrón Pérez,Eulalia Fernández Vallín-Cárdenas,Dianelys Qui?ones Pérez
Revista Cubana de Investigaciones Biom??dicas , 1999,
Abstract: Se realizó una revisión bibliográfica sobre las pautas de tratamiento recomendadas en la infección causada por Helicobacter pylori. Las altas tasas de erradicación logradas por los esquemas triple y cuádruple, hacen que éstos sean utilizados como primera y segunda línea de tratamiento respectivamente. Se relacionan las afecciones asociadas con la infección, en las que se debe utilizar el tratamiento erradicador. El uso de antimicrobianos, en zonas donde la resistencia era elevada, redujo la eficacia del esquema utilizado. La vacuna anti-H. pylori constituyó una novedosa opción de tratamiento. La utilización de diferentes sitios mucosos de vacunación con adyuvantes de baja toxicidad, también se trataron en este trabajo. La efectividad terapéutica de la vacuna, según los autores, resultó alta en modelos experimentales y alcanzó 100 % de protección frente a la infección por esta bacteria gramnegativa. A bibliographic review on the schedules of treatment recommended in the infection caused by Helicobacter pylori was made. The high rates of erradication attained by the triple and quadruple therapies allow their use as first and second line treatment, respectively. Those affections associated with the infection, in which the erradicating treatment should be applied, are related. The utilization of antimicrobials in areas where the resistance was high reduced the efficacy of the therapy used. The anti-H. pylori vaccine became a new option of treatment. The use of different mucous sites of vaccination with adjuvants of low toxicity was also dealt with in this paper. The therapeutic effectiveness of the vaccine according to the authors proved to be high in experimental models and achieved 100 % of protection against the infection caused by this gramnegative bacterium.
Infección por Helicobacter pylori en pacientes con mucosa sana y con gastritis erosiva Helicobacter pylori infection present in patients with a healthy mucosa and erosive gastritis
María Teresa Martínez Echavarría,Guillermo Noa Pedroso
Revista Cubana de Medicina , 2009,
Abstract: Helicobacter pylori es una bacteria que coloniza e infecta la mucosa del epitelio gástrico del hombre. La infección condiciona la aparición de una gastritis que puede evolucionar hacia úlcera péptica, adenocarcinoma gástrico o linfoma tipo MALT. En otros casos, la infección se presenta de forma silente. Se estudió le presencia de HP en pacientes con gastritis y en otros con mucosa sana que acudieron a la Consulta de Endoscopia, del Hospital Clinicoquirúrgico "Hermanos Ameijeiras", por desórdenes en las vías del tracto digestivo superior. Se investigaron 50 pacientes, 30 tenían gastritis erosiva y 20, la mucosa sana, confirmado histológicamente. Se detectó Helicobacter pylori por amplificación de un fragmento del gen ure A mediante la reacción en cadena de la polimerasa, en el 90 % de los casos con gastritis erosiva y en el 75 % de los sujetos con mucosa sana. La razón de productos cruzados (OR) fue 3 con un intervalo de confianza de 0,52-18,9. Se concluyó que la infección por HP es tan elevada en los pacientes con gastritis como en aquellos con mucosa gástrica sana. Helicobacter pylori (HP) is a bacterium causing colonization and infection of gastric epithelium of man. Infection allows appearance of a gastritis that may to evolve to a peptic ulcer, a gastric adenocarcinoma, or a type MALT lymphoma. In other cases, infection has a silent presentation. Authors studied presence of HP in patients with gastritis and in others with a healthy mucosa, seen in endoscopy consultation of "Hermanos Ameijeiras" Surgical Clinical Hospital by others disorders in high digestive tract pathways. Fifty patients were investigated, 30 of them had an erosive gastritis, and 20 had a healthy mucosa histology confirmed. HC was detected by amplification of a fragment of Ure A gen, by means of polymerase chain reaction (PCR), in 90% of cases with erosive gastritis, and in 75 % of subjects with a healthy mucosa. The reason of odds ratio (OR) was of 3 with a confidence interval (IC) of 0.52-18.9. We conclude that HP infection is so high in patients with gastritis than in those with a healthy gastric mucosa.
Prevalência de infec??o por Helicobacter pylori em crian?as avaliadas no Hospital de Clínicas de Porto Alegre, RS, Brasil
SOUSA, Marcelo Basso;LUZ, Letícia Perondi;MOREIRA, Daniel Martins;BACHA, Omar Moreira;CHULTZ, Rogério Menezes;EDELWEISS, Maria Isabel;
Arquivos de Gastroenterologia , 2001, DOI: 10.1590/S0004-28032001000200010
Abstract: objectives ? to determinate prevalence of helicobacter pylori infection in a group of symptomatic patients between 2 and 18 years old who were submitted to gastric biopsy during upper endoscopy done in the period of 1990-97. to correlate the histological findings with clinical and endoscopical data. methods ? a cross-sectional study done after review of clinical and histopathological data. histopathological sections were reviewed by a pathologist, who did not know the clinical information and the previous histopathological reports. results ? among 181 patients evaluated, prevalence of helicobacter pylori infection was 24.86% (45 positive cases). in pathological analysis, gastritis was found in 38/45 of the positive helicobacter pylori patients and in 45/136 negative helicobacter pylori. gastric ulceration was found in 6/45 positive helicobacter pylori and in 3/136 negative helicobacter pylori. conclusion ? this study stated a significative association between helicobacter pylori infection and pathological abnormalities in children evaluated in the "hospital de clínicas de porto alegre", rs, brazil.
Tratamiento de la infección por Helicobacter pylori: Comentario al respecto
Padrón Pérez,Noel; Fernández Vallín-Cárdenas,Eulalia; Qui?ones Pérez,Dianelys;
Revista Cubana de Investigaciones Biom??dicas , 1999,
Abstract: a bibliographic review on the schedules of treatment recommended in the infection caused by helicobacter pylori was made. the high rates of erradication attained by the triple and quadruple therapies allow their use as first and second line treatment, respectively. those affections associated with the infection, in which the erradicating treatment should be applied, are related. the utilization of antimicrobials in areas where the resistance was high reduced the efficacy of the therapy used. the anti-h. pylori vaccine became a new option of treatment. the use of different mucous sites of vaccination with adjuvants of low toxicity was also dealt with in this paper. the therapeutic effectiveness of the vaccine according to the authors proved to be high in experimental models and achieved 100 % of protection against the infection caused by this gramnegative bacterium.
Cytotoxic isolates of Helicobacter pylori from Peptic Ulcer Diseases decrease K+-dependent ATPase Activity in HeLa cells
Awasthi Shanjana, Ayyagari Archana
BMC Gastroenterology , 2003, DOI: 10.1186/1471-230x-3-31
Abstract: The patients were retrospectively grouped on the basis of endoscopic and histopathological observation as having gastritis or peptic ulcer. The HeLa cells were incubated with the broth culture filtrates (BCFs) of H. pylori isolates from patients of both groups and observed for the cytopathic effects: morphological changes and viability. In addition, the K+-dependent ATPase activity was measured in HeLa cells extracts.The cytotoxin production was observed in 3/7 (gastritis) and 4/4 (peptic ulcer) H. pylori isolates. The BCFs of cytotoxin producing H. pylori strains reduced the ATPase activity of HeLa cells to 40% of that measured with non-cytotoxin producing H. pylori strains (1.33 μmole Pi/mg protein and 3.36 μmole Pi/mg protein, respectively, p < 0.05). The decreased activity of ATPase enzyme or the release of cytotoxin also correlated with the increased pathogenicity indices of the patients.Our results suggest that the isolation of cytotoxic H. pylori is more common in severe form of acid peptic diseases (peptic ulcer) than in gastritis patients from India. Also the cytotoxin released by H. pylori impairs the ion-transporting ATPase and is a measure of cytotoxicity.Helicobacter pylori is a spiral Gram negative, microaerophilic bacterial parasite that inhabitates gastric epithelium [1]. The long-term H. pylori infection has been found associated with gastritis, gastric and duodenal ulcer, B-cell lymphoma and adenocarcinoma of the stomach [2-4]. H. pylori infection is common in both developed and developing countries. It is estimated that in developed countries 30–50% of the adult population is infected. In developing countries, the prevalence of H. pylori infection is noted even higher-approximately 80% [5,6]. Interestingly, not all the H. pylori infected individuals develop peptic ulcer or gastric cancer. A significant number of patients have milder form of disease, like inflammation in stomach and duodenum [7,8]. Such discriminatory behavior of H. pylori can be l
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