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Search Results: 1 - 10 of 2067 matches for " Helenio Ferrer Gracias "
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Infección con poliovirus vacunal en ni?os con anticuerpos neutralizantes homólogos, inducidos por vacunaciones con VOP-T
Más Lago,Pedro; Ferrer Gracias,Helenio; Goyenechea Hernández,ángel;
Revista Cubana de Higiene y Epidemiolog?-a , 2003,
Abstract: an investigation on seroconversion and circulation of the viruses excreted from the oral polio vaccine (opv) was made for some years and its results were introduced into the improvement of the program for erradicating this disease. a retrospective analysis of the data showed new results that are still into effect in the context of the program for the world erradication of polio. 98 children under 2 were administered 2 doses of trivalent oral polyo vaccine (t-opv) with an interval of 4 weeks. stool samples were obtained weekly from the first dose to 4 weeks after the second dose. serum samples were taken before vaccination and 4 weeks later. the percentage of isolation of homologous poliovirus in children with no previous antibodies is higher (116.7 %) than the one attained in children with previous antibodies (34.2 %). the percentages of total isolations from poliovirus in children with seroconversion (72.4 %) is higher than those registered in children with booster (167 %). the cases without isolations in seroconversions with previous heterologous antibodies plus the boosters without anamnestic reaction, or homologous isolations allowed to infer a selflimited silent circulation. the interference to the polioviruses by the non-polio enteroviruses, together with the increase of antibodies by the campaigns, caused that the circulations of poloivirus were selflimited shortly after concluding the mass campaign
Infección con poliovirus vacunal en ni os con anticuerpos neutralizantes homólogos, inducidos por vacunaciones con VOP-T
Pedro Más Lago,Helenio Ferrer Gracias,ángel Goyenechea Hernández
Revista Cubana de Higiene y Epidemiología , 2003,
Abstract: Una investigación sobre seroconversión y circulación de los virus excretados de la vacuna oral antipoliomielítica (VOP), se realizó durante varios a os y sus resultados se introdujeron en el perfeccionamiento del programa para la erradicación de la enfermedad. Un análisis retrospectivo de los datos demostró nuevos resultados que mantienen vigencia en el contexto del programa de la erradicación mundial. En 98 ni os menores de dos a os de edad se administraron dos dosis de vacuna oral antipoliomielítica trivalente (VOP-T) con intervalo de 4 sem. Se obtuvieron muestras de heces fecales semanalmente, desde la primera dosis hasta 4 sem después de la segunda dosis y también de sueros antes de la vacunación y 4 sem después de la segunda dosis. El porcentaje de aislamiento de poliovirus homólogos en ni os sin anticuerpos previos fue más alto (116,7 %) que los obtenidos en ni os con anticuerpos previos (34,2 %), mientras los porcentajes de aislamientos totales a poliovirus en ni os con seroconversión (72,4 %) resultó más elevado que los registrados en ni os con reactivación (167 %). Los casos sin aislamientos en seroconversiones con anticuerpos heterólogos previos más las reactivaciones sin estímulos, anamnesis o aislamientos homólogos permitieron inferir una circulación silenciosa autolimitada. La interferencia a los poliovirus por los enterovirus no polio, conjuntamente con el incremento de anticuerpos por las campa as, produjo que las circulaciones de poliovirus fueran autolimitadas a corto tiempo después de concluida la campa a masiva. An investigation on seroconversion and circulation of the viruses excreted from the oral polio vaccine (OPV) was made for some years and its results were introduced into the improvement of the program for erradicating this disease. A retrospective analysis of the data showed new results that are still into effect in the context of the program for the world erradication of polio. 98 children under 2 were administered 2 doses of trivalent oral polyo vaccine (T-OPV) with an interval of 4 weeks. Stool samples were obtained weekly from the first dose to 4 weeks after the second dose. Serum samples were taken before vaccination and 4 weeks later. The percentage of isolation of homologous poliovirus in children with no previous antibodies is higher (116.7 %) than the one attained in children with previous antibodies (34.2 %). The percentages of total isolations from poliovirus in children with seroconversion (72.4 %) is higher than those registered in children with booster (167 %). The cases without isolations in seroconversions with
Doctor en Ciencias Conrado del Puerto Quintana (1929 - 2004)*
Helenio Ferrer Gracia
Revista Cubana de Higiene y Epidemiología , 2004,
Abstract:
Casos de poliomielitis paralítica asociada a la vacuna oral antipoliomielítica en Cuba (1963-2006) Cases of paralytic poliomyelitis associated with oral antipoliomielytis vaccine in Cuba (1963-2006)
Pedro Más Lago,Helenio Ferrer,ángel Goyenechea,ángel Galindo
Revista Cubana de Higiene y Epidemiología , 2008,
Abstract: OBJETIVO: divulgar los indicadores de poliomielitis paralítica asociada encontrados en 44 a os en ni os vacunados con oral antipoliomielítica, suministrada exclusivamente en campa as masivas de vacunación durante el período de 1963 a 2006 y reportar el riesgo de poliomielitis paralítica asociada a la vacuna con relación a diferentes aspectos epidemiológicos. MéTODOS: se realizó un estudio retrospectivo en 596 casos de parálisis fláccida aguda en ni os ingresados en hospitales pediátricos, basado en investigaciones virológicas y detección de diferentes variables epidemiológicas. RESULTADOS: de 113 pacientes estudiados se aislaron 120 agentes virales y 30 fueron identificados como poliovirus. Los datos clínicos y epidemiológicos en 596 casos de parálisis fláccida aguda permitieron categorizar a 20 ni os afectados con poliomielitis paralítica asociada a la vacuna. Todos los casos se presentaron en ni os menores de un a o, vacunados con oral antipoliomielítica con estrategias de campa as masivas de vacunación exclusivamente y 19 fueron producidos por la primera dosis. El riesgo global en los ni os vacunados con primera dosis de 1963 a 2006 fue 1 en 379 888 (7 217 866 dosis administradas/19 casos con poliomielitis paralítica asociada a la vacuna). Los casos de poliomielitis paralítica asociada a la vacuna se han presentado esporádicos o en un grupo de 8 casos en el período 1989-1992. El riesgo de primera dosis en casos esporádicos fue 1 en 612 864 y en el grupo de 1 en 84 670. El riesgo en casos agrupados es 7,2 veces mayor que los ocurridos en casos aislados. Particularmente en el a o 1992, que coincidió con una epidemia de neuropatía epidémica, el riesgo fue de 1 en 52 140, lo que representó un incremento de 11,8 veces a lo ocurrido en casos esporádicos. Los ni os de 4-7 meses de edad también tuvieron un riesgo mayor que fue 1 en 132 812. CONCLUSIONES: se identificaron aspectos epidemiológicos que incrementaron el riesgo de poliomielitis paralítica asociada a la vacuna, en los cuales coinciden aspectos de deficiencias nutricionales. AIM: to disseminate the indicators of associated paralytic poliomyelitis found during 44 years in children that received the oral antipoliomyelitis vaccine, which was only administered in massive vaccination campaigns from 1963 to 2006, and to report the risk of vaccine-associated paralytic poliomyelitis as regards different epidemiological aspects. METHODS: a retrospective study was undertaken in 596 cases of acute flaccid paralysis in children admitted in pediatric hospitals, based on virology researches, and on the detection
Honrar, Honra. Panel en Homenaje al Aniversario 85 del natalicio del Ministro Dr. Sergio del Valle Jiménez To honour does one's honour. Panel paying Homage to Dr. Minister Sergio Del Valle Jiménez on occasion of his 85th birthday Anniversary
María del Carmen Amaro Cano,Henoch Garriga,Helenio Ferrer Gracia,Carlos Scorza Sánchez
Revista Habanera de Ciencias M??dicas , 2012,
Abstract: En homenaje al General de División y Héroe de la República de Cuba, Dr. Sergio del Valle Jiménez, excelente médico obstetra; militante del Movimiento 26 de Julio; combatiente de la Sierra Maestra; Jefe de la Fuerza Aérea al triunfo revolucionario; Jefe del Estado Mayor General de las FAR, cuando el ataque mercenario a Playa Girón y la Crisis de Octubre, momentos difíciles que compartiera con el Comandante en Jefe Fidel Castro Ruz; Ministro del Interior (1968-1979) y Ministro de Salud Pública (1979-1985), se realizó un Coloquio en el Museo de la Revolución _gracias al apoyo solidario de su Director y equipo de especialistas y trabajadores- en vísperas del 85 Aniversario de su natalicio, el 15 de abril. El Panel estuvo integrado por compa eros, quienes compartieron distintas etapas de su vida estudiantil, laboral, de la clandestinidad y la Sierra Maestra, y las responsabilidades asumidas después del triunfo revolucionario. Una nutrida asistencia demostró su interés por conocer más del hombre excepcional a quien se recordaba en ese día. Todos los panelistas coincidieron en que las principales virtudes que destacaron a este admirado médico revolucionario son la honestidad, nobleza, modestia, firmeza revolucionaria, sentido de justicia, decisión y coraje. Dos interesantes intervenciones del público asistente, así lo corroboraban. La Moderadora, en las conclusiones, leyó dos juicios de valor emitidos por el máximo líder de la Revolución Cubana acerca del extraordinario hombre a quien se le rendía tributo, y agradeció a todos su asistencia, especialmente a las decenas de personas, quienes se mantuvieron de pie durante las dos horas del coloquio. It was carried out a colloquy at the museum of the Revolution to do homage to General of Division and hero of the Republic of Cuba Dr. Sergio del Valle Jiménez, militant of "26 de Julio" movement, combatant at Sierra Maestra mountains, Commander of the Air Force at the Revolutionary triumph in 1959 and General chief of the revolutionary armed forces(FAR) when the mercenary attack in Playa Giron and the so called "October Crisis", these last two difficult moments that he shared with Commander in chief Fidel Castro Ruz, He was also in charge of the Cuban "Ministerio del Interior"during the period 1968 - 1979 and Minister of Public Health for six years (1979 - 1985). We would like to thanks the jointly support of the director of the museum as well as all the specialists and workers of this institution who made possible this activity on the eves of the 85th anniversary of his birthday on April 15th. The panelists of the ac
Casos de poliomielitis paralítica asociada a la vacuna oral antipoliomielítica en Cuba (1963-2006)
Más Lago,Pedro; Ferrer,Helenio; Goyenechea,ángel; Galindo,ángel; Sarmiento,Luis; Fonseca,Magilé; Morier,Luis; Palomera,Rosa;
Revista Cubana de Higiene y Epidemiolog?-a , 2008,
Abstract: aim: to disseminate the indicators of associated paralytic poliomyelitis found during 44 years in children that received the oral antipoliomyelitis vaccine, which was only administered in massive vaccination campaigns from 1963 to 2006, and to report the risk of vaccine-associated paralytic poliomyelitis as regards different epidemiological aspects. methods: a retrospective study was undertaken in 596 cases of acute flaccid paralysis in children admitted in pediatric hospitals, based on virology researches, and on the detection of different epidemiological variables. results: 120 viral agents were isolated from 113 studied patients. 30 were identified as poliovirus. the clinical and epidemiological data from 596 cases of acute flaccid paralysis allowed to categorize 20 children affected with vaccine-associated paralytic poliomyelitis. all the cases were children under one that were exclusively administered the oral antipoliomyelitis vaccine through the strategy of the massive vaccination campaigns. 19 of them were caused by the first dose. global risk in children vaccinated with the first dose from 1963-2006 was of one in 379 888 (7 217 866 doses administered/19 cases with vaccine-associated paralytic poliomyelitis). cases of vaccine-associated paralytic poliomyelitis have been sporadic or in a group of 8 cases during 1989-1992. the risk of first dose in sporadic cases was of one in 612 864, and in the group of 1 in 84 670. the risk of grouped cases is 7.2 times higher than those occurred in isolated cases. particularly, in 1992, coinciding with an outbreak of epidemic neuropathy, the risk was of one in 52 140, which represented an increase of 11.8 times compared with sporadic cases. children aged 4-7 months old also had a higher risk of 1 in 132 812. conclusions: there were identified epidemiological aspects that augmented the risk of vaccine-associated paralytic poliomyelitis, in which the aspects of nutritional deficiencies coincided.
Estimation of Natural Gas Production, Import and Consumption in Brazil Based on Three Mathematical Models  [PDF]
Antonio Carlos Gracias, Sérgio Ricardo Louren?o, Marat Rafikov
Natural Resources (NR) , 2012, DOI: 10.4236/nr.2012.32007
Abstract: A mathematical model capable of providing a forecast of future consumption and import of natural gas is essential for the planning of the Brazilian energy matrix. The aim of this study is to compare three mathematical models, logistic model or model of Verhulst, exponential model or the model of Malthus and the model of von Bertalanffy to analyze the possibilities of these models to describe the evolution of production, import and consumption of natural gas in Brazil, from data provided by the energy balance of the Ministry of Mines and Energy (MME) from 1970 to 2009. A projection of the production and the import of natural gas up to 2017 is made with the models studied in this article and compared with the Brazilian Ten-Year Plan for Expansion of Energy (PDE). At the end of this paper a comparison with the Hubbert model for Brazilian natural gas production is made. These data were adjusted to use the differential equations which describe the models of population growth. All the computer work used in this article: graphics, resolution of differential equations, calculations of linearization and the least squares fitting was prepared in the software MatLab. The results obtained by means of graphs show that the population dynamics models (logistic, exponential and von Bertalanffy) can be applied in modeling the production, import and consumption of natural gas in Brazil.
Exploring measurement biases associated with esophageal Doppler monitoring in critically ill patients in intensive care unit
Stawicki Peter,Braslow Benjamin,Gracias Vicente
Annals of Thoracic Medicine , 2007,
Abstract: Background : Esophageal Doppler monitoring (EDM) is utilized in numerous clinical settings. This study examines the relationship between pulmonary artery catheter (PAC) and EDM-derived hemodynamic parameters, concentrating on gender- and age-related EDM measurement biases. Materials and Methods : Prospective study of EDM use in ventilated surgical ICU patients. Parameters examined included demographics, diagnosis, resuscitation endpoints, cardiac output (CO) and stroke volume from both devices, number of personnel and time needed to place equipment, time to data acquisition, duration of use, complications of placement. Results : Fifteen patients (11 men, 4 women, mean age 47 years) were included. Most common diagnoses included trauma (7/15) and sepsis (4/15). Insertion time and time to data acquisition were shorter for EDM than for PAC ( P < 0.001). The EDM required an average of 1.1 persons to place (2.4 for PAC, P =0.002). Mean EDM utilization time was 12.4 h. There was a fair CO correlation between EDM and PAC (r = 0.647, P < 0.001). Overall, the EDM underestimated CO relative to PAC (bias -1.42 ± 2.08, 95% CI: -5.58-2.74), with more underestimation in women (mean bias difference of -1.16, P < 0.001). No significant age-related measurement bias differences between PAC and EDM were noted. Significant reductions in lactate and norepinephrine requirement were noted following EDM monitoring periods. Conclusions : This study found that the EDM significantly underestimated cardiac output in women when compared to PAC. Clinicians should be aware of this measurement bias when making therapeutic decision based on EDM data. Significant reductions in lactate and norepinephrine requirement during EDM monitoring periods support the clinical usefulness of EDM technology.
Integration of 4G Wireless Technologies in a Test-Bed Environment
Amir Esmailpour,Veljko Knezevic,Maria Gracias,Gelareh Kokabian
International Journal of Wireless & Mobile Networks , 2013,
Abstract: Amongst other mandates of the 4th Generation of Wireless Networks (4G), integration and unification ofvarious technologies is a critical subject. In this paper an end-to-end wireless network deployment in atest-bed environment is established to demonstrate a practical model for integration of various wirelesstechnologies used by ISPs to provide services to large and small enterprise customers. The focus of thisresearch is on the Quality of Service (QoS) considerations in a WiFi-WiMAX integrated network. Theresults show that integrated deployment does not deteriorate throughput as compared to a standaloneWiMAX system. The throughput of approximately 967.5 kbps was observed throughout the path andshows a steady performance across various parts of the network regardless of the technology involved.Numerical results also confirm that outcomes for effectiveness of the QoS routines defined in theproposed architecture are not severely affected by the integration.
Currency Areas: Public Debt, Inflation and Unemployment  [PDF]
Carlos Encinas-Ferrer
Open Journal of Applied Sciences (OJAppS) , 2014, DOI: 10.4236/ojapps.2014.44021
Abstract: Can public debt, inflation and unemployment tell us something about optimal or not optimal currency areas? In this paper, I compare the behavior of these variables in two countries, Mexico and the United States of America (USA), along with the member countries of the Euro Zone (European Monetary Union, or EMU). The main purpose is to know the divergence between public debt, average inflation ﹣0% in the graphs—in the main cities or regions of the first two, and compare them with the countries of the EMU. The period of 2001-2012 is chosen to be the years in which the Euro has been circulating among member countries of the Monetary Union (EMU). We find significant differences that allow us to determine the faults that the criteria of divergence on these variables had on the founding treaty of the European Monetary Union.
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