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Search Results: 1 - 10 of 187018 matches for " Helena Pinto de; Almeida "
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Cooperation and best practices within the COTEC Innovative SME Network
Bento,Paulo; Sousa,Helena Pinto de; Almeida,Miguel;
Economia Global e Gest?o , 2011,
Abstract: this article investigates what members consider to be the advantages of cooperating with and belonging to the cotec innovative sme network, and identifies which have been and should be the best cooperation practices. these advantages were measured through enquiries conducted at the beginning of 2008 and 2010, while the best practices were assessed by means of both the 2010 enquiry and the innovation scoring (is). the results were not always conclusive or robust; nevertheless, we found that the three main advantages cited in 2008 were repeated in 2010 and that there are a number of statistically significant relationships between some selected advantages and categories such as ict sector, manufacturing industry or collaborative profile “technological partner”. although the crossing of best practices (past and future) with the is was inconclusive, the results could serve as a reference for cotec and its members.
Cooperation and best practices within the COTEC Innovative SME Network Coopera o e boas práticas na Rede PME Inova o COTEC
Paulo Bento,Helena Pinto de Sousa,Miguel Almeida
Economia Global e Gest?o , 2011,
Abstract: This article investigates what members consider to be the advantages of cooperating with and belonging to the COTEC Innovative SME Network, and identifies which have been and should be the best cooperation practices. These advantages were measured through enquiries conducted at the beginning of 2008 and 2010, while the best practices were assessed by means of both the 2010 enquiry and the Innovation Scoring (IS). The results were not always conclusive or robust; nevertheless, we found that the three main advantages cited in 2008 were repeated in 2010 and that there are a number of statistically significant relationships between some selected advantages and categories such as ICT sector, manufacturing industry or collaborative profile “technological partner”. Although the crossing of best practices (past and future) with the IS was inconclusive, the results could serve as a reference for COTEC and its members. Este artigo investiga aquelas que, no entender dos seus membros, s o as vantagens de cooperar e pertencer à Rede PME Inova o COTEC e, ainda, aquelas que têm sido e que devem ser as melhores práticas de coopera o. A explora o das referidas vantagens fez-se a partir de inquéritos, levados a cabo no início de 2008 e de 2010, enquanto as melhores práticas foram avaliadas com base nas respostas ao inquérito de 2010 e no Innovation Scoring (IS). Os resultados nem sempre foram conclusivos ou robustos; contudo, constatámos que as três principais vantagens de 2008 repetiram-se em 2010 e que existiam algumas rela es estatisticamente significantes entre certas vantagens selecionadas e categorias como sector TIC, indústria transformadora ou perfil colaborativo parceiro tecnológico . Em rela o às melhores práticas, passadas e futuras, o cruzamento com o IS revelou-se inconclusivo; ainda assim, os resultados poder o servir de referência à COTEC e aos seus membros.
The Performance as Educator in the Health System: Implications for Brazilian Health Workers Education Process  [PDF]
Alva Helena De Almeida
Creative Education (CE) , 2014, DOI: 10.4236/ce.2014.511106
Abstract:

This paper has the purpose of discussing the performance as health educators in the Brazilian Unified Health System (SUS) and also emphasizing the importance of the educational process for health workforce qualification as well as management device of health systems. This performance has been a strong strategy for SUS implementation process in Brazil.

Genotypic identification of Cryptosporidium spp. isolated from hiv-infected patients and immunocompetent children of S?o Paulo, Brazil
Araújo, Ana Julia Urias dos Santos;Kanamura, Herminia Yohko;Almeida, Marcos Eduardo de;Gomes, Aparecida Helena de Souza;Pinto, Thais Helena Lemos;Da Silva, Alexandre Januário;
Revista do Instituto de Medicina Tropical de S?o Paulo , 2008, DOI: 10.1590/S0036-46652008005000003
Abstract: cryptosporidium isolates identified in fourteen stool samples, collected from five hiv-infected patients and nine immunocompetent children, living in the sate of s?o paulo, brazil, were submitted to a molecular analysis using a nested pcr followed of restriction fragment length polymorphism (rflp), for genetic characterization. the analysis was based on digestion with rsai restriction enzyme of a dna fragment amplified from the cryptosporidium oocyst wall protein (cowp) gene. based on this analysis, four samples were identified as cryptosporidium parvum, eight as cryptosporidium hominis and two presented a profile that correspondedto cryptosporidium meleagridis when compared to the standards used in the analysis. the use of molecular methods can be helpful to identify source of infections and risk factors related to cryptosporidium infection in our communities.
Produtos naturais: atualidade, desafios e perspectivas
Pinto, Angelo C.;Silva, Dulce Helena Siqueira;Bolzani, Vanderlan da Silva;Lopes, Norberto Peporine;Epifanio, Rosangela de Almeida;
Química Nova , 2002, DOI: 10.1590/S0100-40422002000800009
Abstract: this article offers an overview on the historical facts and the recent state of art of chemistry of natural products which, in the course of 25 years of sbq, have led to the present development of this area in brazil. in addition, this article deals with the last trends on natural products in brazil and also in developed countries.
Frequency of oral mucositis and microbiological analysis in children with acute lymphoblastic leukemia treated with 0.12% chlorhexidine gluconate
Soares, Andréa Ferreira;Aquino, Ana Rafaela Luz de;Carvalho, Cyntia Helena Pereira de;Nonaka, Cassiano Francisco Weege;Almeida, Dulce;Pinto, Le?o Pereira;
Brazilian Dental Journal , 2011, DOI: 10.1590/S0103-64402011000400009
Abstract: in view of the morbidity potential of oral complications in patients with leukemia, this study evaluated the clinical and microbiological alterations that occur in the oral mucosa of children with acute lymphoblastic leukemia (all) undergoing antineoplastic chemotherapy and prophylactic administration of 0.12% chlorhexidine gluconate. the sample consisted of 17 children aged 2 to 12 years that underwent clinical examination of the oral mucosa for the detection of oral lesions. in addition, biological material was collected from labial and buccal mucosa for microbiological analysis. oral mucositis was observed in only 5 (29.4%) patients. microbiological analysis revealed a reduced number of potentially pathogenic microorganisms, such as coagulase-negative staphylococci (47%), candida albicans (35.3%), klebsiella pneumoniae (5.9%), enteropathogenic escherichia coli (5.9%), and stenotrophomonas maltophilia (5.9%). patients with oral mucositis showed a higher frequency of coagulase-negative staphylococci (80%) when compared with patients with normal oral mucosa (33.3%). in conclusion, the results of the present study suggest that the prophylactic use of 0.12% chlorhexidine gluconate reduces the frequency of oral mucositis and oral pathogens in children with all. in addition, the present findings suggest a possible relationship between coagulase-negative staphylococci and the development of oral mucositis.
Ensaio de proficiência para análise de ditiocarbamatos em polpa de banana
Bastos, Lucia Helena Pinto;Góes, Heloisa Cronemberger de Araújo;Cardoso, Maria Helena Wohlers Morelli;Gouvêa, Adherlene Vieira;Dias, Denise de Paula;Almeida, Renato Rubim Ribeiro de;Nóbrega, Armi;Abrantes, Shirley;
Química Nova , 2007, DOI: 10.1590/S0100-40422007000100007
Abstract: a proficiency assay of the determination of dithiocarbamate pesticide residues in banana was carried out. fourteen laboratories participated in this study. homogeneity and stability testing were performed by incqs on the samples sent to the laboratories. analytical results supplied by the pesticide residues laboratory of the vwa/kvw, amsterdam, holland, were used to define the designated value for the thiram concentration in the study samples. results: fifty percent of the participating laboratories had satisfactory results. efforts are needed to improve the precision of the analytical results and to decrease the number of false negative results observed.
Características e potencial tecnológico da carne da capivara
Pinto, Marcos Franke;Ponsano, Elisa Helena Giglio;Almeida, Ana Paula da Silva;Heinemann, Riana Jord?o Barrozo;Souza, Wilson Machado de;
Ciência Rural , 2007, DOI: 10.1590/S0103-84782007000300041
Abstract: the good rank capybara meat has reached within the exotic meat market justifies studies on its physical-chemical composition and also on the improvement of the production process. with that aim, longissimus dorsi and semimembranosus muscles of male animals ageing 12 to 18 months were evaluated about composition and technological properties. it was found a low fat content in capybara meat - 0.4% and 0.3% for l. dorsi and semimembranosus muscles, respectively. a inverse correlation (p<0.001) was found between sarcomere length and shear force. l. dorsi showed a shorter sarcomere lenght and a higher shear force (p<0.001) than semimembranosus muscle (1.88 mm and 2.43 mm; 11.2 kg and 9.1kg, respectively), what denotes that capybara ham meat is tenderer than loin meat. moreover, trimmings and viscera were used in the elaboration of meat products as hamburger, pátê and mortadella. sensory analysis of those products showed good acceptance.
Influência de fatores genéticos e ambientais sobre as características produtivas no rebanho eqüino do Exército Brasileiro
Campos, Vinício Aurélio Lagoas;McManus, Concepta;Fuck, Beatriz Helena;Cassiano, Lizangela;Pinto, Bruno Freitas;Braga, Auro;Louvandini, Helder;Dias, Laila Talarico;Teixeira, Rodrigo de Almeida;
Revista Brasileira de Zootecnia , 2007, DOI: 10.1590/S1516-35982007000100004
Abstract: this study aimed to estimate genetic and phenotypic parameters for weight and height (4860 records) of equines from four genetic groups: brazilian showjumper (bh), thoroughbred (psi), hanoverian (han) and no defined breed (srd). data collected from 1977 to 2002 on 1629 animals was provided by the brazilian army. models used for analyses included the fixed effects of month and year of foaling and measuring, age of dam, foal sex and genetic group. foaling month did not affect height or weight of the horses, except for older animals. the sex effect influenced height but not weight of 21-month-old animals and adults. the genetic group influenced height between 18 and 21 months of age, as well as height of adults. bh was less influenced by environmental effects than srd. heritabilities for weights of bs were high at various ages, but were low for height. overall, heritability estimates for weight of bh and srd increased as age increased.
Sulforaphane Induces Oxidative Stress and Death by p53-Independent Mechanism: Implication of Impaired Glutathione Recycling
José Miguel P. Ferreira de Oliveira, Maria Costa, Tiago Pedrosa, Pedro Pinto, Catarina Remédios, Helena Oliveira, Francisco Pimentel, Luís Almeida, Concei??o Santos
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0092980
Abstract: Sulforaphane (SFN) is a naturally-occurring isothiocyanate best known for its role as an indirect antioxidant. Notwithstanding, in different cancer cell lines, SFN may promote the accumulation of reactive oxygen species (ROS) and cause cell death e.g. by apoptosis. Osteosarcoma often becomes chemoresistant, and new molecular targets to prevent drug resistance are needed. Here, we aimed to determine the effect of SFN on ROS levels and to identify key biomarkers leading to ROS unbalance and apoptosis in the p53-null MG-63 osteosarcoma cell line. MG-63 cells were exposed to SFN for up to 48 h. At 10 μM concentration or higher, SFN decreased cell viability, increased the%early apoptotic cells and increased caspase 3 activity. At these higher doses, SFN increased ROS levels, which correlated with apoptotic endpoints and cell viability decline. In exposed cells, gene expression analysis revealed only partial induction of phase-2 detoxification genes. More importantly, SFN inhibited ROS-scavenging enzymes and impaired glutathione recycling, as evidenced by inhibition of glutathione reductase (GR) activity and combined inhibition of glutathione peroxidase (GPx) gene expression and enzyme activity. In conclusion, SFN induced oxidative stress and apoptosis via a p53-independent mechanism. GPx expression and activity were found associated with ROS accumulation in MG-63 cells and are potential biomarkers for the efficacy of ROS-inducing agents e.g. as co-adjuvant drugs in osteosarcoma.
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