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Search Results: 1 - 10 of 2837 matches for " Helen Manolopoulou "
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Active Modified Atmosphere Packaging of Fresh-cut Bell Peppers: Effect on Quality Indices
Helen Manolopoulou,Gregory Lambrinos,George Xanthopoulos
Journal of Food Research (JFR) , 2012, DOI: 10.5539/jfr.v1n3p148
Abstract: Fresh-cut green bell peppers (Capsicum annuum L.) were stored in modified atmosphere packaging (MAP) made of impermeable high-density polyethylene film. Two in-packaging atmospheres and storage temperatures (0 oC and 5 oC) were tested. The respiration rate of the unpackaged produce and the in-package gas concentration, mass loss, firmness, skin colour, ascorbic acid and visual quality of the packaged produce were estimated. Cutting, increased respiration rate of the unpackaged produce by 24% compared to the intact produce for the same storage temperature. After 5 days of storage at 5 °C, significant O2 depletion of the active modified atmosphere was found. Limited mass loss (0.4-0.5% of the initial mass) and firmness degradation were estimated in both storage temperatures due to the beneficial effect of packaging. The hue angle (h*) reduction was limited in all cases and the initial green colour was preserved. Initial ascorbic acid content was preserved at 0 °C, but significantly increased at 5 °C. The visual quality of the packaged produce was assessed by six trained panelists and found that was not significantly changed at 0 °C storage. In conclusion, the tested active MAP maintained the initial quality indices of fresh-cut peppers (cv. Twingo F1) for up to 10 days at 0 °C but not at 5 °C.
Effect of Storage Conditions on the Sensory Quality, Colour and Texture of Fresh-Cut Minimally Processed Cabbage with the Addition of Ascorbic Acid, Citric Acid and Calcium Chloride  [PDF]
Eleni Manolopoulou, Theodoros Varzakas
Food and Nutrition Sciences (FNS) , 2011, DOI: 10.4236/fns.2011.29130
Abstract: The aim of this study was to investigate the effect of storage conditions on the sensory quality, colour and texture of fresh-cut cabbage during the addition of ascorbic acid, citric acid and calcium chloride. Ascorbic acid maintained the overall quality for 14 days at 0℃ and 7 days at 5℃; no difference, however, was observed regarding browning of cut surface compared to the control sample at both storage temperatures. Calcium chloride maintained the overall quality and cut surface browning for 14 days at both storage temperatures. It was also found that citric acid 1% can be used for minimally processed cabbage. Soaking with citric acid helped retain the color and increased the overall acceptance and organoleptic quality of fresh cut cabbage; it reduced browning of the cut surface and protected against formation of black specks. Citric acid treatment combined with low temperature storage (0℃) prolonged the shelf life of minimally processed cabbage for 22 days, time sufficient for acceptable marketing of the product. The lightness of minimally processed cabbage decreased linearly from 70.94 ± 6 to 63.8 ± 8.5 - 61.3 ± 8 units for the chemical treatments during 22 days of storage at 0℃. Hue angle values during storage time were also significantly influenced by chemical treatments mainly at 0℃.
Introduction to Issue 1
Nicos C. Sifakis,Eleni Manolopoulou
Research Papers in Language Teaching and Learning , 2010,
Abstract: This paper does not have an abstract.
Efficient High-Dimensional Gaussian Process Regression to calculate the Expected Value of Partial Perfect Information in Health Economic Evaluations
Anna Heath,Ioanna Manolopoulou,Gianluca Baio
Statistics , 2015,
Abstract: The Expected Value of Perfect Partial Information (EVPPI) is a decision-theoretic measure of the "cost" of uncertainty in decision making used principally in health economic decision making. Despite having optimal properties in terms of quantifying the value of decision uncertainty, the EVPPI is rarely used in practise. This is due to the prohibitive computational time required to estimate the EVPPI via Monte Carlo simulations. However, a recent development has demonstrated that the EVPPI can be estimated by non parametric regression methods, which have significantly decreased the computation time required to approximate the EVPPI. Under certain circumstances, high-dimensional Gaussian Process regression is suggested, but this can still be prohibitively expensive. Applying fast computation methods developed in spatial statistics using Integrated Nested Laplace Approximations (INLA) and projecting from our high-dimensional input space allows us to decrease the computation time for fitting these high-dimensional Gaussian Processes from around 13 minutes to 10 seconds. We demonstrate that the EVPPI calculated using this new method for Gaussian Process regression is in line with the standard Gaussian Process regression method and that despite the methodological complexity of this new method, R functions are available in the package R-INLA to implement it simply and efficiently.
A Review of Methods for the Analysis of the Expected Value of Information
Anna Heath,Ioanna Manolopoulou,Gianluca Baio
Statistics , 2015,
Abstract: Over recent years Value of Information analysis has become more widespread in health-economic evaluations, specifically as a tool to perform Probabilistic Sensitivity Analysis. This is largely due to methodological advancements allowing for the fast computation of a typical summary known as the Expected Value of Partial Perfect Information (EVPPI). A recent review discussed some estimations method for calculating the EVPPI but as the research has been active over the intervening years this review does not discuss some key estimation methods. Therefore, this paper presents a comprehensive review of these new methods. We begin by providing the technical details of these computation methods. We then present a case study in order to compare the estimation performance of these new methods. We conclude that the most recent development based on non-parametric regression offers the best method for calculating the EVPPI efficiently. This means that the EVPPI can now be used practically in health economic evaluations, especially as all the methods are developed in parallel with R
Osteoprotegerin Secretion by Mevastatin via p38MAPK and NF-kB  [PDF]
Helen Smith
Open Journal of Rheumatology and Autoimmune Diseases (OJRA) , 2012, DOI: 10.4236/ojra.2012.22006
Abstract: Osteoprotegerin (OPG) is a protein produced by many cell types that has the remarkable property of inhibiting bone loss. It does this by binding to the key bone resorptive cytokine, receptor activator of NF-kB ligand (RANKL). This cytokine is produced mainly by osteoblastic cells and is instrumental in osteoclast differentiation. If the ratio of RANKL:OPG increases, bone resorption increases and results in bone loss in diseases such osteoporosis, rheumatoid arthritis and hypercalcaemia of malignancy. Hence, if drugs can be found that increase OPG, this will decrease the activity of osteoclasts and therefore bone resorption. Statins are cholesterol lowering drugs that have recently been shown to increase bone formation in rodents. It was hypothesised from this finding that this could be due to an increase in OPG production. If these commonly prescribed drugs could be used to prevent bone loss or to increase bone formation then this may prove a useful means of reducing fracture risk in patients. Treating Saos-2 osteoblast-like cells in vitro with mevastatin increased OPG production and secretion through the mevalonate pathway. A failure of geranylgeranylation of Rho and/or farnesylation of Ras proteins leads to an increase in PI-3K activation then AKT activation leading to several different signaling pathways such as MAPK’s and NF-kB. NF-kB and p38MAPK inhibitors prevented the statin stimulation of OPG but not the decrease in cell number, suggesting that statins regulate OPG secretion via PI-3K, p38MAPK and NF-kB.
Religious Wear (Uniforms) in Psychiatry  [PDF]
Helen Bright
Open Journal of Psychiatry (OJPsych) , 2014, DOI: 10.4236/ojpsych.2014.42015

Uniforms represent more than just a body cover. There could be symbols of status, power, authority, values, beliefs, identity, wealth representation, self-protection, health and safety, suppression of individuality and identification on one hand by the wearer. The observers may perceive uniforms differently based on their experiences, expectations, education, perceptual ability, conformity, status, power, self-confidence, and need for trust and communication without barrier or judgment. Forty five adult mentally ill patients (21 female and 24 male) were administered questionnaires with Linkert Scale regarding how approachable or off-putting they find casual and religious wear in social worker. Significantly more patients preferred casual wear to religious. Chi squared test equals 28.689 with p value of less than 0.0001 for four degrees of freedom.

The Influence of L2 Transfer on L3 English Written Production in a Bilingual German/Italian Population: A Study of Syntactic Errors  [PDF]
Helen Forsyth
Open Journal of Modern Linguistics (OJML) , 2014, DOI: 10.4236/ojml.2014.43036

This study attempts to examine and identify instances of negative “interlanguage transfer” (Sharwood Smith & Kellerman, 1986), which is a phenomenon belonging to the broader field of crosslinguistic influence, in written L3 English production in a bilingual Italian/German population. Transfer from learners’ L2 has attracted increasing attention over recent years (De Angelis & Selinker, 2001; Jessner, 2006) and research has suggested various potential triggers for facilitative and negative L2 transfer, as well as producing mixed results regarding the individual aspects of language that may be susceptible to transfer from a learner’s L2. Quantitative data were collected from 46 subjects in the form of questionnaires enquiring about language backgrounds and attitudes, and written summaries. The Statistical Package for Social Science was used to analyse specific instances of written syntactic errors resulting from both L1 and L2 transfer and these were then examined in the light of the questionnaire responses in order to identify possible determining factors behind any L2 transfer for both linguistic groups. Results provided evidence of negative syntactic L2 transfer from German and Italian in English L3, yet the possible determining factors were sometimes unexpected and not necessarily identical for both groups. This study suggests that L2 transfer in multilingual settings is a very real possibility which may be of future interest in terms of multilingual language processing and have consequences for the L3 classroom.

Designing Economics Electives with a Significant Writing Component  [PDF]
Helen Schneider
Creative Education (CE) , 2017, DOI: 10.4236/ce.2017.84040
Abstract: This paper presents a design for the structure and assessment of a research paper assignment in an upper level economics elective with a significant writing component. Writing component design focuses on what graduating economics majors should be able to do with the knowledge they acquire in the major and on their ability to create original analysis and empirical models in courses with and without an econometrics prerequisite. The author provides writing workshop and minimal marking approaches to improving the writing skills of undergraduates. Finally, the paper presents the link between main modules of the course and proficiencies we expect from graduating majors.
Percutaneous dilatational tracheostomy with a lightwand device
K Kokkinis, T Vrettos, K Lefkaditi, P Manolopoulou, K Zbouki
Critical Care , 2000, DOI: 10.1186/cc384
Abstract: Elective PDT was performed in 55 critically ill patients, mean age 54.5 ± 16 (22-72), intubation time 6.5 ± 3.2 (3-14) days.The procedure was undertaken on the bedside using the Griggs-Portex PDT set as has been already described [1]. Before cannulation of the trachea the trachlight device (trachlight, Leardal Medical) was inserted into the endotracheal tube with the tip at the end of the tube. By pulling back the endotracheal tube with the trach-light we examined the anatomy of the trachea and the location of the first and second trachea rings. Besides the proper position of the end of the tube above the first trachea ring was achieved. Afterwards we continued with the PDT technique. At the end the exact tracheotomy site and the correct placement of the tracheostomy tube was evaluated by endoscopy.The procedure lasted from 7 to 21 min (m.v. 9.5 min). The maneuver with the trachlight device lasted between 40-80s Perioperative complications are listed below:1) Hemorrhage minor: 2 patientsHemorrhage major: 0 patients2) Premature extubation of the translaryngeal tube: 0 patients3) Puncture of the endotracheal tube/cuff: 0 patients4) Paramedian puncture of the trachea: 0 patients5) Hypoxemia: 0 patientsPDT is a simple bedside procedure with a low complication race. The combination with the trachlight device gives the opportunity for better identification of the anatomy of the trachea as well as the correct placement of the endotracheal tube above the first endotracheal ring. These contribute to better conditions for safe and accurate tracheal puncture and cannulation.
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