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Search Results: 1 - 10 of 198988 matches for " Heidi N. Fridolfsson "
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Caveolin and caveolae in age associated cardiovascular disease
Heidi N. Fridolfsson,Hemal H. Patel
老年心脏病学杂志(英文版) , 2013,
Abstract: It is estimated that the elderly (> 65 years of age) will increase from 13% 14% to 25% by 2035. If this trend continues, > 50% of the United States population and more than two billion people worldwide will be “aged” in the next 50 years. Aged individuals face formidable challenges to their health, as aging is associated with a myriad of diseases. Cardiovascular disease is the leading cause of morbidity and mor-tality in the United States with > 50% of mortality attributed to coronary artery disease and > 80% of these deaths occurring in those age 65 and older. Therefore, age is an important predictor of cardiovascular disease. The efficiency of youth is built upon cellular signaling scaffolds that provide tight and coordinated signaling. Lipid rafts are one such scaffold of which caveolae are a subset. In this review, we consider the importance of caveolae in common cardiovascular diseases of the aged and as potential therapeutic targets. We specifically address the role of caveolin in heart failure, myocardial ischemia, and pulmonary hypertension.
Caveolin and caveolae in age associated cardiovascular disease
Heidi N Fridolfsson,Hemal H Patel,
Heidi N. Fridolfsson
,Hemal H. Patel

老年心脏病学杂志(英文版) , 2013,
Abstract: It is estimated that the elderly (> 65 years of age) will increase from 13%?14% to 25% by 2035. If this trend continues, > 50% of the United States population and more than two billion people worldwide will be “aged” in the next 50 years. Aged individuals face formidable challenges to their health, as aging is associated with a myriad of diseases. Cardiovascular disease is the leading cause of morbidity and mortality in the United States with > 50% of mortality attributed to coronary artery disease and > 80% of these deaths occurring in those age 65 and older. Therefore, age is an important predictor of cardiovascular disease. The efficiency of youth is built upon cellular signaling scaffolds that provide tight and coordinated signaling. Lipid rafts are one such scaffold of which caveolae are a subset. In this review, we consider the importance of caveolae in common cardiovascular diseases of the aged and as potential therapeutic targets. We specifically address the role of caveolin in heart failure, myocardial ischemia, and pulmonary hypertension.
La experiencia semestral
Heidi Ca?ón
Anuario Turismo y Sociedad , 2003,
Abstract:
Urinary incontinence in Norwegian nursing home residents  [PDF]
Liv Heidi Skotnes, Ragnhild Omli, Ulla Romild, Ove Hellzèn, Esther Kuhry
Open Journal of Nursing (OJN) , 2012, DOI: 10.4236/ojn.2012.22018
Abstract: Urinary incontinence is a multi-factorial condition that has a high impact on older persons living in nursing homes. While urinary incontinence is common, only a small percentage of nursing home residents have an official diagnosis. Factors influencing urinary incontinence in this population are poorly understood. The aim of this study was to evaluate the prevalence of urinary incontinence in Norwegian nursing home residents and to study the factors associated with urinary incontinence in this population. Residents from six different nursing homes were included in this study. Data on sex, age, medication, comorbid illnesses, urinary incontinence and the use of absorbent pads was collected. Barthel`s Index of Activities of Daily Living (ADL) was used to estimate residents’ functional levels. Post-voiding residual urine was measured by means of a portable ultrasound. A questionnaire was completed by the nursing staff for each of the residents. In total, 173 residents participated in the study. One hundred and twenty-two residents (69%) were incontinent for urine and 144 used absorbent pads (83%). Fourteen percent of residents used absorbent pads ‘just to make sure’. They did not have a history of urinary incontinence. Low ADL score, dementia and urinary tract infection were significantly associated with incontinence for urine. The prevalence of urinary incontinence in Norwegian nursing homes is high. Absorbent products are frequently used without a history of urinary incontinence. Physical impairment, dementia and urinary tract infections are significantly associated with urinary incontinence.
Content of nursing discharge notes: Associations with patient and transfer characteristics  [PDF]
Rose Mari Olsen, Ove Hellzén, Liv Heidi Skotnes, Ingela Enmarker
Open Journal of Nursing (OJN) , 2012, DOI: 10.4236/ojn.2012.23042
Abstract: Background: In situations of care transfer of older people from hospital to home care at discharge, exchanging relevant and necessary information about the patient’s health status and individual needs are of importance to ensure continuity and appropriate nursing follow-up care. Objective: The objectives of the study were to: 1) examine the content of nurses’ discharge notes of older patients’ discharged from hospital to home care, and 2) investigate the association between the content of discharge notes and characteristics of patient and transfer. Methods: The nursing discharge notes of 70 older patients admitted to a geriatric unit and a general medicine ward at a local hospital in central Norway were analysed. The discharge notes were structured in accordance with the Well-being, Integrity, Prevention, and Safety (VIPS) model. Mean, standard deviations, and independent sample t-tests were performed to show and examine differences in use of VIPS keywords in relation to patient and transfer characteristics. To examine if use of VIPS keywords could be predicted by patient and transfer characteristics, linear multiple regression analyses were used. Results: Significant differences for mean scores on used VIPS keywords in the discharge note were found for gender, age, and medical department facility. While gender and medical department facility were significant predictors of mental related keywords in the discharge note, medical department facility was a significant predictor of physical related keywords. Conclusions: The result of this study indicate that documentation of patient status in the nursing discharge note of older patients transferred from hospital to home care is incomplete and are influenced by patient and transfer characteristics. In order to ensure continuity and appropriate nursing follow-up care, we emphasize the need for a more comprehensive approach to older patients, and that this must be reflected in the nursing discharge note.
Relación entre la helmintiasis intestinal y el estado nutricional-hematológico en ni?os de una escuela rural en el estado Sucre, Venezuela
Figuera,Lourdes; Kalale,Heidi; Marchán,Edgar;
Kasmera , 2006,
Abstract: a parasitological, nutritional and hematological evaluation was carried out on 103 children of both sexes between 4-12 years of age from a rural school at santa fe, sucre state, venezuela, from january-march 2003. fecal samples were analyzed using a fresh test, willis malloy, and the quantitative kato-katz method. nutritional status was determined by anthropometric indexes combinations. haematological parameters were evaluated by classical methods and the degree of eosinophilia was expressed in absolute eosinophil counts. exactly 93.2% of schoolchildren were found to have parasites with high poliparasitism (83.3%). intestinal helminths prevalence was 82.5%, highlighted by 69.4% of trichuris trichiura and ascaris lumbricoides association, with a predominant light intensity of infestation. around 91.2% (31/34) of individuals with malnutrition presented helminthiasis. eosinophilia was found in 97.6% of schoolchildren infested by helminths (p< 0,001). and 83.3% (20/24) were infested by helminths in the group of children with anemia (23.3%). about 88.8% of children with intestinal helminthiasis belonged to the vth level socioeconomic stratum. these findings suggest that the school population evaluated lives in a high helminth hyperendemic area, consistent with the socioeconomic stratum found. additionally, it was established that eosinophilia in these schoolchidren is a factor associated with intestinal helminthiasis.
Primer estudio de Enterobacter sakazakii en alimentos en Cuba First study on Enterobacter sakazakii in foodstuffs in Cuba
Virginia Leyva,Heidi Ruiz,Mayrín Machín,René Tejedor
Revista Cubana de Salud Pública , 2008,
Abstract: Introducción Enterobacter sakazakii es uno de los microorganismos patógenos emergentes que han hecho su aparición en los últimos a os, fundamentalmente como contaminante ocasional de las fórmulas infantiles en polvo. En países en vías de desarrollo no existen suficientes investigaciones sobre este microorganismo, en Cuba este constituye el primer estudio realizado. Objetivos Conocer la presencia de E. sakazakii en muestras de leche en polvo de importación. Métodos Se analizaron 60 muestras de leche en polvo, entera y descremada, provenientes de nueve países, se siguió la técnica recomendada por autoridades reguladoras de EE.UU., con la inclusión de pruebas bioquímicas convencionales como alternativa antes de aplicar el sistema de identificación API 20E. Se empleó el agar hierro Kligler y el agar citrato de Simmons; en aquellas cepas con imagen sugestiva de Enterobacter se comprobó la obtención de triptofano a partir de indol, reacción de Voges Proskauer y rojo de metilo, descarboxilación de lisina y ornitina, dihidrólisis de la arginina, producción de ácido de sacarosa, dulcitol, adonitol, rafinosa y sorbitol. Resultados Se obtuvo crecimiento de enterobacterias en 26 muestras. Una sola cepa dio resultado presuntivo de E. sakazakii por pruebas bioquímicas, la misma se confirmó por API 20E para 1,6 % de positividad. Conclusiones En general la calidad microbiológica de las muestras de leche estudiadas fue buena. La técnica empleada para determinar E. sakazakii en muestras de leche en polvo, con la inclusión de pruebas bioquímicas convencionales, es factible de realizar en Cuba, para minimizar los costos asociados a la utilización de API 20E. Sería importante continuar estos estudios en áreas hospitalarias, especialmente aquellas donde se preparan fórmulas lácteas para recién nacidos. Introduction Enterobacter sakazakii is an emerging pathogen that has been isolated in milk powder preparations for infant in the last few years. Practically there is no research works about this microorganism in developing countries; in Cuba this is the first study. Objectives To detect the presence of E. sakazakii in imported milk powder samples. Methods Sixty samples of whole and skimmed powdered milk imported from 9 countries were analyzed. Before applying API 20E Kit, the recommended technique by US regulatory bodies including conventional biochemical tests was used. Kligler′s iron agar and Simmons′s citrate agar were employed; other tests such as obtaining of triptophane from indole, Voges Proskauer reaction, methyl red, lysine and ornitine decarboxylation, arginine dihyd
Fit “n” Cool Kids: Effects of Peer-Modeling and Goal Setting on Physical Activity  [PDF]
Jessyka N. Larson, Timothy A. Brusseau, Maria M. Newton, Stuart J. Fairclough, Heidi Wengreen, James C. Hannon
Open Journal of Preventive Medicine (OJPM) , 2018, DOI: 10.4236/ojpm.2018.84008
Abstract: Background: Decreasing the risk of overweight and obesity from an early age is imperative and efforts should focus on fostering children’s physical activity (PA). Within school-based interventions, there is insufficient evidence on the effectiveness of the use of character peer-modeling and goal setting to increase physical activity. Therefore, the purpose of this study was to examine the impact of a school-based intervention on PA and enjoyment of PA in grades 3 - 5 elementary school age children at two urban elementary schools. Methods: Participants were 95 students of 8 - 10 years old; activity monitors were used to assess physical activity. Daily physical activity and enjoyment was recorded at baseline, intervention, and at a 6-school-week follow-up. Results: PA significantly increased in the intervention school averaging 5549 steps at baseline, 5889 steps during the intervention, and 6515 during follow-up (p < 0.05). Participants significantly increased their moderate to vigorous physical activity from 28.54 min at baseline to 30.06 minutes at week 4 and 36.45 during follow-up (p < 0.05). There was no change in enjoyment levels from baseline to follow-up. Conclusion: The Fit “n” Cool Kids intervention presents the potential of peer-modeling and goal setting for increasing PA at school. Continued interventions in schools may positively influence children’s healthy living patterns.
Openness in Scandinavian Classrooms: Student Perceptions of Teaching Practices and High Achievers of Civic Knowledge  [PDF]
Lihong Huang, Heidi Biseth
Creative Education (CE) , 2016, DOI: 10.4236/ce.2016.75075
Abstract: In this paper, we explore how teaching practices in classrooms influence students’ civic knowledge achievement in three Scandinavian countries: Denmark, Norway, and Sweden. Using data from the 2009 International Civic and Citizenship Education Study (ICCS), our investigation focuses on the measures of “open classroom climate”, which include seven items that ask students how often they experience each of the seven teaching practices during regular lessons. From the students’ perspective of teaching practices in the classroom, we hypothesize and assume that there should be a balanced combination of classroom practices where each method/activity carries a different weight or level of importance. Applying logistic regression analysis, we assess the effect of each of the practices on the probability with which a student becomes a high achiever of civic knowledge (as represented by odds ratios). Our results show both similarities and differences in the combinations of classroom practices that have contributed to students’ high civic knowledge achievement in the three Scandinavian countries. Our findings provide useful messages to teachers in the classroom, and they also have implications for teacher education and research.
Experimental Study of Fiber Length and Orientation in Injection Molded Natural Fiber/Starch Acetate Composites
Heidi Peltola,Bo Madsen,Roberts Joffe,Kalle N?ttinen
Advances in Materials Science and Engineering , 2011, DOI: 10.1155/2011/891940
Abstract: Composite compounds based on triethyl citrate plasticized starch acetate and hemp and flax fibers were prepared by melt processing. Plasticizer contents from 20 to 35 wt% and fiber contents of 10 and 40 wt% were used. The compounded composites were injection molded to tensile test specimens. The effect of processing, melt viscosity and fiber type on the fiber length was investigated. The lengths of fully processed fibers were determined by dissolving the matrix and measuring the length of the remaining fibers by microscope analysis. A clear reductive effect of the processing on the fiber length was noticed. A reduction of fiber length along the increasing fiber content and the decreasing plasticizer content was also detected. This reduction originated from the increasing shear forces during compounding, which again depended on the increased viscosity of the material. Hemp fibers were shown to remain longer and fibrillate more than flax fibers, leading to higher aspect ratio. Thus, the reinforcement efficiency of hemp fibers by the processing was improved, in contrast with flax fibers. In addition, the analysis of fiber dispersion and orientation showed a good dispersion of fibers in the matrix, and a predominant orientation of the fibers in the melt flow direction. 1. Introduction An increasing interest towards the use of biobased polymers instead of conventional petroleum-based plastic materials can be detected worldwide. Progressing technologies, rising prices of finite resources, and new environmental legislation together with more environmentally concerned consumers are creating a need to compensate petroleum-based materials with bio-based plastics. Within various biomaterials, especially starch-based bioplastics have been widely studied and used due to their low price and good availability. However, the properties of bio-based plastics do not always meet the material requirements of certain applications. Fiber reinforcement of the plastic material can provide higher mechanical properties and thereby wider application possibilities. The most common fiber materials for reinforcement of plastics are glass, carbon, aramid, and polyethylene. To produce natural fiber reinforced composites, various cellulosic fibers from flax, hemp and wood can be used. In thermoplastic starch composites, flax and ramie fibers have been used, resulting in four times higher tensile strengths than the neat plastics [1]. Starch acetates have earlier been reinforced with cellulosic fibers to give composites with enhanced mechanical properties, shock absorbance, and
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