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Search Results: 1 - 10 of 5480 matches for " Hassan Boskabadi "
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The Effect of Traditional Remedies (Camels Thorn, Flixweed and Sugar Water) on Idiopathic Neonatal Jaundice
Hassan Boskabadi,Gholamali Maamouri,Shahin Mafinejad
Iranian Journal of Pediatrics , 2011,
Abstract: Objective:Jaundice is the most common reason of newborns admission to neonatal ward. Many Iranian families give traditional remedies like sugar water, camels thorn and flixweed extracts to breast-fed babies for reducing jaundice. This study investigated the effect of traditional remedies on idiopathic neonatal jaundice. Methods:This prospective study has been performed on 336 babies with idiopathic jaundice in a four year period (2005-2009) at Ghaem hospital, Mashhad, Iran. The babies were divided into two groups. In case group (n=234) breast-fed babies received no remedy and in control group (n=102), traditional remedies were given additional to breast milk and the results recorded and compared. Findings:In the present study significant differences were observed between the two groups in age of admission (6.8±3.2 vs 9.2±3.7 day, P<0.001), serum bilirubin values (17.8 vs 21.3 mg/dl, P<0.001) and percent of weight loss (P<0.01). There were no significant differences between the two groups in birth weight, sex, gestational age and duration of hospitalization, age at jaundice remission, hematocrit value and maternal factors (age, gestational order, pregnancy and labor problems)(P>0.05). Conclusion:Traditional remedies (camels thorn, flixweed and sugar water) cause more weight loss and delayed reexamination of newborns leading to increased hyperbilirubinemia. These remedies may raise pseudo confidence in parents, which postpones reexamination and follow up of the newborns.
Neonatal Complications Related with Prolonged Rupture of Membranes
Hassan Boskabadi,Gholamali Maamouri,Shahin Mafinejad
Macedonian Journal of Medical Sciences , 2011,
Abstract: Background. Prolonged rupture of membranes (PROM) is a common and significant cause of preterm labor and has a major impact on neonatal morbidity and mortality. The aim of this study was to determine maternal risk factors and the prevalence rate of neonatal complications following PROM . This study also detected the role of maternal antimicrobial treatment on neonatal complications.Methods: This cross-sectional study was performed at Ghaem hospital, Mashhad, Iran; from March 2008 to April 2010 to evaluate newborns’ outcome that were born from mothers with prolonged premature rupture of membranes (PROM> 18 hours). Maternal risk factors, antibiotic administration and its influences on neonatal complications were evaluated. Eligible infants were categorized into group I (symptomatic infants), II (mother with chorioamnionitis) and III (asymptomatic infants).Results. 150 infants were included in the study. 12 (7.7%) infants had definitive infections (meningitis, sepsis, pneumonia), 101(67%) infants were premature and 88(58.6%) infants had mothers with a history of antibiotic intake. Maternal risk factors were reported in the following order: previous PROM (10%), addiction (8%), high urinary tract infection (5/3%), diabetes (4.7%), placenta abruption (4.7%), preeclampsia (3/3%) and cercelage (2%). Neonatal complications related with PROM were prematurity (67.3%), respiratory distress syndrome (22.6%), asphyxia (8.6%), meningitis (5.2%), sepsis (4%), pneumonia (1.3%) and death (4.6%). History of antibiotic administration to mothers with PROM was negative in four babies with sepsis and one with meningitis.Conclusion. The most common complication of PROM was prematurity and its side effects, but infection is the most important modifiable complication. Although antimicrobial treatment of women with a history of PROM improves neonatal outcome through reducing neonatal sepsis and respiratory distress syndrome (RDS), but the incidence rate of meningitis and pneumonia may be increased.
Prevalence and Clinical Manifestation of Glucose-6-Phosphate Dehydrogenase Deficiency in Newborns with Hyperbilirubinemia in Mashhad, Iran
Hassan Boskabadi,Masoud Omidian,Shahin Mafinejad
Macedonian Journal of Medical Sciences , 2010,
Abstract: Background. Hyperbilirubinemia is a relatively common disorder among infants and one of the most common reasons is glucose- 6- phosphate dehydrogenase (G6PD) deficiency.Aim. The aim of this study was to determine prevalence rate of enzyme deficiency in newborns with jaundice. We also compared clinical and paraclinical values among G6PD- deficient and normal G6PD infants who were admitted in the hospital due to jaundice.Material and Methods. This prospective descriptive study has been performed on 1568 neonates, with jaundice as a chief complaint, at Ghaem hospital in Mashhad, Iran, in a six- year period. Neonates were screened for G6PD enzyme by the florescent spot method and characteristics such as birth weight, age and weight on admission, hospitalization period, need for exchange and laboratory data [Complete Blood count (CBC), reticulocyte count, indirect and direct bilirubin, coombs test and blood type] were recorded. Statistical analysis was carried out using SPSS 13.5 statistical package.Results. The overall prevalence rate of G6PD deficiency was 5.2% (59/1139 infants) and males were predominated (88.1% vs 11.9%). Significant statistical differences between two groups of normal G6PD and G6PD deficient- neonates, were detected in the age of admission (p=0.001), hematocrit (p=0.000), hospitalization period (p=0.000) and total serum bilirubin (p=0.013). Kernicterus was reported in 6.4% of neonatal Hyperbilirubinemia.Conclusion. G6PD deficiency is a common enzyme defect among newborns in Iran and may cause severe hyperbilirubinemia and kernicterus. By screening all infants and on-time treatment we can prevent further complications of G6PD deficiency disorder.
Serum Interleukin 8 Level as a Diagnostic Marker in Late Neonatal Sepsis
Hassan Boskabadi,Gholamali Maamouri,Jalil Tavakol Afshari,Majid Ghayour Mobarhan
Iranian Journal of Pediatrics , 2010,
Abstract: Objective:Late-onset sepsis is responsible for high morbidity and mortality in newborn infants in the world and in particular in developing countries. In this study, we evaluated whether clinical characteristics, laboratory parameters and measurements of serum interleukin-8 (IL-8) are able to discriminate between late neonatal sepsis and normal baby. Methods:This was a prospective (case-control) study conducted between March 2007and April 2008, at the neonatal intensive care unit, Ghaem Hospital, Mashhad, Iran. The study comprised 93 neonates ≥72 hours of life. The infants were categorized in two groups based on the clinical presentation, and biochemical markers including complete blood count, C-reactive protein (CRP) and blood culture: 1) Control group including 42 infants with routine screening and 2) Case group consisting of 38 infants with definitive infection (positive blood and/or cerebrospinal fluid culture) or clinical sepsis (clinical and laboratory signs of infection without positive blood or CSF culture). Receiver-operating characteristic curves were used for the determination of thresholds for the infection group versus healthy neonate group. Findings:Eighty infants were enrolled in this study. IL-8 and CRP decreased in order of definitive infection,clinical sepsis and healthy subjects respectively (P<0.001). Sensitivity, specificity, positive predictive value, negative predictive value for serum levels were 0.95, 0.1, 0.97, 0.1 for IL-8 and 0.83, 0.86, 0.83, 0.69 for CRP respectively (cut-off point for IL-8 >60pg/ml and for CRP>6mg/dl). Conclusion:IL-8 may be a valid and early predictive marker of neonatal infection. Also, IL-8 is associated with severity of infection.
A 10 Year Survey of Neonatal Kidney Mass in North-East of Iran (Khorasn)
Golam-Ali Mamouri,Hassan Boskabadi,Farhad Heydarian
Iranian Journal of Pediatrics , 2007,
Abstract: Objective: Although abdominal mass in neonates is not common, it is very critical to detect it promptly. 2/3 of neonatal abdominal masses belong to kidney. Correct diagnosis and immediate appropriate management can prevent morbidity and mortality. This study pays special attention to incidence, associated anomalies and mortality rate in those neonates who suffered from palpable kidney mass. Material & Methods: During a period of 10 years 48250 neonates were examined for abdominal mass by neonatalogists or pediatric residents. Sonography in suspected cases of abdominal mass was performed to confirm the diagnosis. In all cases of neonatal death, autopsy was performed.Findings: Thirty out of 48250 neonates had abdominal mass presenting as nephromegaly (1/1600). Polycystic kidneys (PCK) were the most common cause of renal enlargement followed by multicystic kidney disease (MCK) and hydronephrosis. Conclusion: It was revealed that renal mass contained most of abdominal mass in our study and mortality (73%) was higher than other reports. Also, we found that PCK was the most common abdominal mass in our cases. Lung hypoplasia was the most common cause of death in PCK cases.
Clinical Course and Prognosis of Hemolytic Jaundice in Neonates in North East of Iran
Hassan Boskabadi,Gholamali Maamouri,Shahin Mafinejad,Farzaneh Rezagholizadeh
Macedonian Journal of Medical Sciences , 2011,
Abstract: Background: Hemolytic jaundice is the most serious cause of hyperbilirubinemia among neonates. It may develop to kernicterus due to misdiagnosis or inappropriate treatment. The aim of this study is to determine the prevalence rate of hemolytic jaundice, predisposing factors and assessment of treatment and complications in hemolytic jaundice.Methods: This prospective descriptive study has been performed on 1568 newborns with jaundice as their chief complaint, in a seven-year period at Ghaem hospital in Mashhad, Iran. 795 neonates were included in our study (237 infants with hemolytic jaundice and 558 infants with idiopathic jaundice). Complete physical examinations and laboratory tests were performed and data were recorded. Statistical analysis was carried out, using SPSS 11.5 statistical package.Results: In the present study, significant differences were determined between two groups of hemolytic and idiopathic jaundice for total serum bilirubin, hematocrit, time of jaundice appearance, age of admission, hospitalization period and incidence of kernicterus (p<0.001). Newborns with ABO incompatibility (17%), Rh disease (7%), G6PD deficiency (6%) and minor blood group immunization (2%) were developed to hyperbilirubinemia, respectively. Among the newborns affected with kernicterus, 12 cases were placed in group with ABO hemolytic disease (9%), 3 cases were in Rh isoimmunization group (5.5%), 4 cases were in G6PD deficiency group (8.9%) and 9 cases were idiopathic (1.6%).Conclusion: Jaundice due to hemolysis is associated with a higher serum bilirubin and more complications like kernicterus. ABO incompatibility was the most common reason of hemolytic jaundice among neonates in north east of Iran. Special attention to ABO incompatibility and G6PD enzyme screening may decrease complications and improve the prognosis.
Neonatal intensive care unit nosocomial bacterial infections
Ghazvini,Rashed,Boskabadi,Yazdan Panah
Tehran University Medical Journal , 2008,
Abstract: Background: Nosocomial infections increase patients' morbidity, mortality and length of hospital stay especially in neonatal intensive care units (NICUs) and have become a matter of major concern. Controlling and preventing nosocomial infections need enough information about epidemiology of these infections. This study aims at estimating the incidence rate and the most frequent bacteria which cause these infections in neonatal intensive care unit of Ghaem university hospital, Mashhad. Methods: In this study which is performed during a twelve month period in 2004 and 2005 at neonatal intensive care unit of Ghaem hospital, 971 hospitalized neonates were studied. Data were collected considering the standard surveillance protocols. Early onset neonatal nosocomial infections and late onset neonatal infections were defined as illness appearing from birth to seven days and from eight to twenty-eight days postnatal age respectively. Statistical analysis was performed using the χ2 test. Results: In this study 32 cases of nosocomial infections were identified so the incidence rate of nosocomial infection in this ward was 3.29%. Fifteen babies identified with early onset neonatal nosocomial infection and the rest have presented with late onset neonatal infections. In order of frequency, the sites of infection were: primary bloodstream (84.4%) and pneumonia (15.62%). Coagulase negative staphylococci were the most common bacteria (43.74%) isolated in these patients. Other isolated bacteria were Klebsiella pneumonia (31.42%) and other gram negative bacilli such as E.coli, Pseudomonas aeroginosa and Acintobacter spp. The mechanical ventilation and umbilical catheter were associated with nosocomial infections as risk factors in our study (p<0.01). Conclusion: Our findings show that the neonatal intensive care unit of Ghaem hospital has low rate of nosocomial infections. However, as neonatal intensive care unit is an area of great concern in terms of nosocomial infection, preventive measures especially hand washing should be intensified.
Estimation of vital cardiovascular parameters of Iranian population: Using reference equations
Sohrab Hajizadeh,Soghrat Faghihzadeh,Mohammad khaksari,Mohammad-Hosien Boskabadi
Knowledge & Health Journal , 2008,
Abstract: Introduction: Normal subjects are healthy peoples who have no cardiovascular symptoms. These people have usually normal values of cardiovascular parameters. Since reference values are influenced by a variety of factors including age, gender, stature, genetic and geographical region of living, though the reference values of one population should be used for that population. The aim of this study was to identify the physiological values of cardiovascular system in Iran adult population and obtain the reference equations for these parameters. Methods: Sample subjects were selected randomly through different cities in several regions of the country. Healthy individuals were identified after medical examination Cardiac parameters including heart rate, systolic and diastolic blood pressure, and pulse pressure were measured using standard methods and devices by expert researchers. Results: The results obtained were calcified for different ages of men and women. Mean values for each parameters was calculated and then reference equations were derived for each parameters as below. Heart rate = 101.791 – 0.086 (age) – 0.132 (height) Diastolic pressure = 59.068 + 0.129 (age) + 2.653 (sex) + 0.15 (weight) Systolic pressure = 82.078 + 0.454 (age) + 0.64 (height) + 4.293 (sex) +0/63 (weight) Pulse pressure = 18.712 + 0.235 (age) + 0.097 (height) + 1.451 (sex) Conclusion: Using these equations, one can predict cardiac parameters for anyone with his/her features (age, sex, height and weight).
Effect of Antibiotic Therapy on Asymptomatic Bacteriuria in Kidney Transplant Recipients
Mahmoudreza Moradi,Mohammadreza Abbasi,As’ad Moradi,Ali Boskabadi
Urology Journal , 2005,
Abstract: Purpose: Asymptomatic bacteriuria is a very common complication after kidney transplantation and the need for antibiotic therapy is controversial. The aim of this study was to evaluate the effect of antibiotic therapy on the clinical course of asymptomatic bacteriuria in renal transplant recipients. Materials and Methods: In the present study, 88 kidney transplant recipients with asymptomatic bacteriuria were divided into two groups of cases and controls. The patients had been selected from among those with at least 1 year follow-up. In the case group, asymptomatic bacteriuric episodes were treated with antibiotics, and in control group, they were followed without antibiotic therapy. The follow-up period was 9 to 12 months. Bacteriuric episodes, symptomatic urinary tract infection (UTI) episodes, and changes in plasma creatinine level were recorded and compared between the two groups. Results: The rate of bacteriuric episodes and symptomatic UTIs were not significantly different between the two groups (P > 0.05). In addition, level of plasma creatinine did not increase significantly in neither of the groups during the study (P > 0.05). Conclusion: It seems that treatment of asymptomatic bacteriuria in kidney recipients does not decrease the rate of UTI episodes afterwards. Asymptomatic bacteriuria does not affect renal function in short term. Thus, we can abandon antibiotic therapy, subject to careful follow-up.
A New Design Technique of CMOS Current Feed Back Operational Amplifier (CFOA)  [PDF]
Hassan Jassim
Circuits and Systems (CS) , 2013, DOI: 10.4236/cs.2013.41003
Abstract:

A new design technique employing CMOS Current Feedback Operational Amplifier (CFOA) is presented. This design approach applies CFA OTA as input stage cascaded with class AB cross-coupled buffer stage. The performance parameters of CMOS CFOA such as bandwidth, slew rate, settling time are extensively improved compared with conventional CFOA. These parameters are very important in high frequency applications that use CMOS CFOA as an active building block such as A/D converters, and active filters. Also the DC input offset voltage and harmonic distortion (HD) are very low values compared with the conventional CMOS CFOA are obtained. P-Spice simulation results using 0.35 μm MI-ETEC CMOS process parameters shows considerable improvement over existing CMOS CFOA simulated model. Some of the performance parameters for example are DC gain of 67.2 dB, open-loop gain bandwidth product of 104 MHz, slew rate (SR+) of +91.3 V/μS, THD of -67 dB and DC input offset voltage of -0.2 mV.

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