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Search Results: 1 - 10 of 510 matches for " Hana Malinska "
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Genetic determination of an endothelial function and the size of the heart sections in juvenile hypertensives
Vera Adamkova,Jaroslav A. Hubacek,Helena Pistulkova,Hana Malinska
Journal of Applied Biomedicine , 2006,
Abstract: Arterial hypertension is a polygenic disease and about 50 candidate genes have been analysed. Wefollowed the size of the heart sections and the endothelial function in juvenile hypertensives according tothe polymorphisms in the genes for angiotensin converting enzyme (I/D), endothelin 1 (Lys198/Asn) andendothelin 1 converting enzyme (Thr341/Ile).We observed 44 juvenile hypertensives and 94 controls of the same age. An echocardiographicexamination was carried out during standard examinations. The endothelial function was analysed withthe use of ultrasound with high acuity after revoking a reactive hyperaemia. The genotypisations wereperformed using the polymerase chain reaction and restriction analysis. Statistical analyses were carriedout using the BMDP statistical software.There were no differences between controls and hypertensives in alleles frequency. Thehypertensives differed from the control group in the endothelial function (statistically significant). Thehypertensives homozygotes D/D and the heterozygotes Lys198/Asn had a larger left ventricle(statistically significant); the hypertensives with the Thr341/Ile had a larger left ventricle septum(statistically significant) and back wall of the left ventricle (statistically significant) than the controls withthe same genotype.We concluded that the genes for ACE, endothelin 1 and endothelin 1 converting enzyme have aninfluence on the size of the heart sections and on the endothelial function of the juvenile hypertensives.
Similar patterns of rDNA evolution in synthetic and recently formed natural populations of Tragopogon (Asteraceae) allotetraploids
Hana Malinska, Jennifer A Tate, Roman Matyasek, Andrew R Leitch, Douglas E Soltis, Pamela S Soltis, Ales Kovarik
BMC Evolutionary Biology , 2010, DOI: 10.1186/1471-2148-10-291
Abstract: Using Southern blot hybridization and fluorescent in situ hybridization (FISH), we analyzed copy numbers and distribution of these highly reiterated genes in seven lines of synthetic T. mirus (110 individuals) and four lines of synthetic T. miscellus (71 individuals). Variation among diploid parents accounted for most of the observed gene imbalances detected in F1 hybrids but cannot explain frequent deviations from repeat additivity seen in the allotetraploid lines. Polyploid lineages involving the same diploid parents differed in rDNA genotype, indicating that conditions immediately following genome doubling are crucial for rDNA changes. About 19% of the resynthesized allotetraploid individuals had equal rDNA contributions from the diploid parents, 74% were skewed towards either T. porrifolius or T. pratensis-type units, and only 7% had more rDNA copies of T. dubius-origin compared to the other two parents. Similar genotype frequencies were observed among natural populations. Despite directional reduction of units, the additivity of 35S rDNA locus number is maintained in 82% of the synthetic lines and in all natural allotetraploids.Uniparental reductions of homeologous rRNA gene copies occurred in both synthetic and natural populations of Tragopogon allopolyploids. The extent of these rDNA changes was generally higher in natural populations than in the synthetic lines. We hypothesize that locus-specific and chromosomal changes in early generations of allopolyploids may influence patterns of rDNA evolution in later generations.Chromosome counts suggest that between 30 and 100% of angiosperm species are polyploids [1], and Wood et al. [2] propose that 15% of angiosperm speciation events are associated with polyploidy whereas recent genomic studies of selected model and crop species have revealed that all plant genomes sequenced to date have signatures of one or more whole-genome duplications in their evolutionary history [3,4]. The success of newly formed angiosperm
Journal of Special Education and Rehabilitation , 1997,
Forecasting the term structure of crude oil futures prices with neural networks
Jozef Barunik,Barbora Malinska
Quantitative Finance , 2015,
Abstract: The paper contributes to the rare literature modeling term structure of crude oil markets. We explain term structure of crude oil prices using dynamic Nelson-Siegel model, and propose to forecast them with the generalized regression framework based on neural networks. The newly proposed framework is empirically tested on 24 years of crude oil futures prices covering several important recessions and crisis periods. We find 1-month, 3-month, 6-month and 12-month-ahead forecasts obtained from focused time-delay neural network to be significantly more accurate than forecasts from other benchmark models. The proposed forecasting strategy produces the lowest errors across all times to maturity.
Attenuation in a Cylindrical Left Handed Material (LHM) Wave-Guide Structure  [PDF]
Hana Mohammed Mousa
Optics and Photonics Journal (OPJ) , 2012, DOI: 10.4236/opj.2012.21007
Abstract: This paper tackles the wave attenuation along with a cylindrical waveguides composed of a left Handed material (LHM), surrounded by a superconducting or metal wall. I used the transcendental equations for both TE and TM waves. I found out that the waveguide supports backward TE and backward TM waves since both permittivity and magnetic permeability of LHM are negative. I also illustrated the dependence of the TE and TM wave attenuation on the wave frequency and the reduced temperature of the superconducting wall (T/Tc). Attenuation constant increases by increasing the wave frequency and it shows higher values at higher T/Tc. Lowest wave attenuation and the best confinement are achieved for the thickest TE waveguide. LHM-superconductor waveguide shows lower wave attenuation than LHM-metal waveguide.
Stability of Nonlinear Te Surface Waves along the Boundary of Left-Handed Material  [PDF]
Hana Mohammed Mousa
Optics and Photonics Journal (OPJ) , 2012, DOI: 10.4236/opj.2012.22017
Abstract: This paper is concerned with the stability characteristics of nonlinear surface waves propagating along a left-handed substrate (LHM) and a non-linear dielectric cover. These characteristics have been simulated numerically by using the perturbation method. The growth rate of perturbation is computed by solving the dispersion equation of perturbation. I found that the stability of nonlinear surface waves is affected by the frequency dependence of the electric permittivity εh and magnetic permeability μh of the LHM. The spatial evolution of the steady state field amplitude is determined by using computer simulation method. The calculations show that with increasing the effective refractive index nx at fixed saturation parameter μp, the field distribution is sharpened and concentrated in the nonlinear medium. The waves are stable of forward and backward behavior. At higher values of nx, attenuated backward waves are observed.
Special Educational Needs and the Study at the Field of Medicine  [PDF]
Hana Sochorova, Ivona Zavacka
Creative Education (CE) , 2018, DOI: 10.4236/ce.2018.98094
Abstract: The study and the profession at the field of medicine involve high demands on mental and physical capabilities. The objective of this study is the following issue:?in what ways mainly healthy students evaluate opportunities of students with special educational needs (SEN) to study medicine. It is based primarily on their experience of the studies and on their medical practice. To meet the above objective, a questionnaire survey method has been used. The results of the survey could be concluded with general recommendations: the study of general medicine is fully manageable for students with certain SEN such as slight visual or hearing impairments, specific learning disabilities, and internal diseases, while it is manageable in a limited way for students with physical disability of legs. The study of students with SEN such as severe visual or hearing impairment, locomotor disability of the upper limbs and disability of fine motoric skills and mental illness, will be very difficult and complicated even if the university considerably adapts to these conditions. In the case of students with SEN, making the decision regarding future profession in health care should always be realistic and based on individuals and with respect to their future employability.
Nephrotic syndrome unfavorable course correlates with downregulation of podocyte vascular endothelial growth factor receptor (VEGFR)-2
Danuta Ostalska-Nowicka,Agnieszka Malinska,Maciej Zabel,Wojciech Witkiewicz
Folia Histochemica et Cytobiologica , 2011, DOI: 10.5603/9443
Abstract: Idiopathic nephrotic syndrome (INS) in children is most commonly caused by primary glomerulopathies. Morphological lesions observed in INS might be secondary to inflammatory factors of mainly extra-renal origin. The vascular endothelial growth factor (VEGF) family is regarded as playing a crucial role in this pathomechanism. The aim of the present work was to analyze the possible relation between VEGF-C and VEGF receptor (VEGFR)-2 expressions at electron microscopy level in different INS cases. The study group comprised 18 children with minimal change disease (MCD), 30 patients diagnosed with diffuse mesangial proliferation (DMP) and 11 subjects with focal segmental glomerulosclerosis (FSGS). An indirect immunohistochemical assay employing monoclonal anti-VEGF-C and anti-VEGFR-2 antibodies was applied in the study. The immunohistochemical expression of VEGF-C within podocyte cytoplasm was significantly increased in DMP subjects who were resistant to steroids and in all FSGS patients compared to MCD children and controls (p < 0.05). VEGF-C over-expression in these cases was followed by downregulation of VEGFR-2. Nephrotic syndrome progression correlates with the downregulation of podocyte VEGFR-2. For this reason, decreased VEGFR-2 expression in the podocyte processes of children with idiopathic nephrotic syndrome might be regarded as a potent factor of unfavorable prognosis. (Folia Histochemica et Cytobiologica 2011; Vol. 49, No. 3, pp. 472–478)
Aitchison, Kenneth, 2011. Breaking New Ground: How Archaeology Works.
Hana Koriech
Papers from the Institute of Archaeology , 2013, DOI: 10.5334/pia.410
Abstract: Book Review: Aitchison, Kenneth, 2011. Breaking New Ground: How Archaeology Works. (Kindle Edition) £2.87
INTERACTION PATHS IN CLASS AND THEIR RELATION TO SOCIAL CLIMATE OF A CLASS / Interak né v zby v triede a ich vz ah k sociálnej klíme
Hanuliaková Hana
Technológia vzdelávania , 2009,
Abstract: The paper analyses the importance and significance of interaction and mutual social relations in class throughout the educational process. The quality and efficiency of their working is an important and decisive indicator both of pedagogical influence of the teacher and of the activities of pupils and their approaches towards school activities. Mutual relations in class are reflected in the whole lives of pupils as well as in the teachers', while their wide occupation affects many parts of education. One of the components of pedagogical - didactic activities of a teacher is provision and increase of educational environment and climate of a class. The problem of social relations is closely connected with the social climate of a class, its creation and support.Príspevok analyzuje vyznam a d le itos interakcie a vzájomnych sociálnych vz ahov v triede po as eduka ného procesu. Kvalita a efektívnos ich fungovania je vyznamnym a smerodajnym ukazovate om i u pedagogického p sobenia u ite a na iakov, alebo aktivity iakov a ich postojov k kolskej práci. Vzájomné vz ahy v triede sa vyznamne odrá ajú v celom ivote iakov a u ite ov v triede, pri om svojím irokym záberom ovplyvňujú mnohé sú asti edukácie. Jednou zo zlo iek pedagogicko-didaktickej innosti u ite a je zabezpe ovanie a zefektívňovanie eduka ného prostredia a klímy danej triedy. V súvislosti s problematikou sociálnych vz ahov je v úzkom kontakte sociálna klíma kolskej triedy, jej kreovanie a podporovanie.
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