Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99


Any time

2019 ( 126 )

2018 ( 905 )

2017 ( 893 )

2016 ( 876 )

Custom range...

Search Results: 1 - 10 of 76722 matches for " Han-Jun Jin "
All listed articles are free for downloading (OA Articles)
Page 1 /76722
Display every page Item
The Peopling of Korea Revealed by Analyses of Mitochondrial DNA and Y-Chromosomal Markers
Han-Jun Jin,Chris Tyler-Smith,Wook Kim
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0004210
Abstract: The Koreans are generally considered a northeast Asian group because of their geographical location. However, recent findings from Y chromosome studies showed that the Korean population contains lineages from both southern and northern parts of East Asia. To understand the genetic history and relationships of Korea more fully, additional data and analyses are necessary.
Succession and innovation of Chinese traditional surgery: a perspective on the history
TANG Han-Jun
Zhong Xi Yi Jie He Xue Bao , 2005,
Abstract: Facing the challenge of modern medicine, how to develop Chinese traditional surgery is a question. The tremendous heritage of traditional Chinese medicine (TCM) is the springhead of the development and innovation of TCM. Succession and innovation is an eternal subject for the development of Chinese traditional surgery. In order to improve Chinese traditional surgery, we should explore traditional medical literature, and carry forward the theories of Chinese traditional surgery
Mitochondrial DNA Haplogroup Analysis Reveals no Association between the Common Genetic Lineages and Prostate Cancer in the Korean Population
Wook Kim, Tag-Keun Yoo, Dong-Jik Shin, Hyun-Wook Rho, Han-Jun Jin, Eun-Tak Kim, Yoon-Sun Bae
PLOS ONE , 2008, DOI: 10.1371/journal.pone.0002211
Abstract: Mitochondrial DNA (mtDNA) variation has recently been suggested to have an association with various cancers, including prostate cancer risk, in human populations. Since mtDNA is haploid and lacks recombination, specific mutations in the mtDNA genome associated with human diseases arise and remain in particular genetic backgrounds referred to as haplogroups. To assess the possible contribution of mtDNA haplogroup-specific mutations to the occurrence of prostate cancer, we have therefore performed a population-based study of a prostate cancer cases and corresponding controls from the Korean population. No statistically significant difference in the distribution of mtDNA haplogroup frequencies was observed between the case and control groups of Koreans. Thus, our data imply that specific mtDNA mutations/lineages did not appear to have a significant effect on a predisposition to prostate cancer in the Korean population, although larger sample sizes are necessary to validate our results.
High frequencies of Y-chromosome haplogroup O2b-SRY465 lineages in Korea: a genetic perspective on the peopling of Korea
Soon-Hee Kim, Ki-Cheol Kim, Dong-Jik Shin, Han-Jun Jin, Kyoung-Don Kwak, Myun-Soo Han, Joon-Myong Song, Won Kim, Wook Kim
Investigative Genetics , 2011, DOI: 10.1186/2041-2223-2-10
Abstract: In general, we found East Asian populations to be characterized by male haplogroup homogeneity, showing major Y-chromosomal expansions of haplogroup O-M175 lineages. Interestingly, a high frequency (31.4%) of haplogroup O2b-SRY465 (and its sublineage) is characteristic of male Koreans, whereas the haplogroup distribution elsewhere in East Asian populations is patchy. The ages of the haplogroup O2b-SRY465 lineages (~9,900 years) and the pattern of variation within the lineages suggested an ancient origin in a nearby part of northeastern Asia, followed by an expansion in the vicinity of the Korean Peninsula. In addition, the coalescence time (~4,400 years) for the age of haplogroup O2b1-47z, and its Y-STR diversity, suggest that this lineage probably originated in Korea. Further studies with sufficiently large sample sizes to cover the vast East Asian region and using genomewide genotyping should provide further insights.These findings are consistent with linguistic, archaeological and historical evidence, which suggest that the direct ancestors of Koreans were proto-Koreans who inhabited the northeastern region of China and the Korean Peninsula during the Neolithic (8,000-1,000 BC) and Bronze (1,500-400 BC) Ages.The Koreans are geographically a Northeast Asian group, who are thought to be most closely related to Altaic language-speaking populations. Anthropological and archaeological evidence suggests that the early Korean population was related to Mongolian ethnic groups, who inhabited the general area of the Altai Mountains and the Lake Baikal regions of southeastern Siberia [1]. Based on archaeological data, the earliest modern human lithic cultures date from 25,000 to 45,000 years ago in the Altai Mountains and southeastern Siberia and the Korean Peninsula [2,3]. According to Korea's founding myths, the Gojoseon (the first state-level society) was established around 2,333 BC in the region of southern Manchuria, but later stretched from the northeastern region of
Lack of Association between Y-Chromosomal Haplogroups and Prostate Cancer in the Korean Population
Wook Kim, Tag-Keun Yoo, Sung-Joo Kim, Dong-Jik Shin, Chris Tyler-Smith, Han-Jun Jin, Kyoung-Don Kwak, Eun-Tak Kim, Yoon-Sun Bae
PLOS ONE , 2007, DOI: 10.1371/journal.pone.0000172
Abstract: The Y chromosome has recently been suggested to have an association with prostate cancer risk in human populations. Since this chromosome is haploid and lacks recombination over most of its length, haplotypes constructed from binary markers throughout the chromosome can be used for association studies. To assess the possible Y-chromosomal contribution to prostate cancer risk, we have therefore analyzed 14 Y-chromosomal binary markers in 106 prostate cancer cases and 110 controls from the Korean population. In contrast to previous findings in the Japanese population, no statistically significant difference in the distribution of Y-chromosomal haplogroup frequencies was observed between the case and control groups of Koreans. Thus, our data imply that the previously reported associations between Y-chromosomal lineages and a predisposition to, or protection against, prostate cancer might be explained by statistical fluctuations, or by genetic effects that are seen only in some environments.
Application of Improved K-Means Algorithm to Analysis of Online Public Opinions

TANG Han-Qing,WANG Han-Jun,

计算机系统应用 , 2011,
Abstract: Combining background application requirement of online public opinion analysis, this paper firstly introduces the processing of text information, and then discusses the K-means algorithm of the text clustering, according to its characteristic that clustering results depend on the centers of initial clustering, and improves it. Based on the thought that text title can express its content, the improved algorithm uses sparse character vector to express text title, calculates the sparse similarity of them and ascertains the centers of initial clustering. The experiments show that the method improves the clustering accuracy. Compared with another algorithm based on the principle of maximum and minimum distance, the improved method heightens the efficiency and ensures the clustering accuracy.
A new image hiding scheme based on multi-secret sharing

HOU Zheng-feng,GAO Han-jun,

计算机应用 , 2008,
Abstract: 提出了一种新的图像隐藏方案,该方案糅合了多重秘密共享思想与LSB算法,生成的影子图像约为秘密图像的1/t,从而减小了载体图像的容量.本方案允许任意选取 (t-1)次多项式的模数p,并根据该模数p将秘密图像的若干个像素点拼接成一个数据单元,有效克服了Thien方案中秘密图像需进行置乱处理的缺陷.此外,本方案构造的多项式明显少于Thien方案和Li Bai方案.
Integration Solution for Electricity Transaction and Operation System Based on SOA

WANG Qiang,WANG Han-Jun,

计算机系统应用 , 2010,
Abstract: As national electricity market reform and development, and enterprise information integration process, the early electricity transaction and operation system is very difficult to adapt to new requirements. This paper presents a technical architecture based on SOA design model of power trading system using SCA\SDO programming model and web service to build electricity trading operation system. It solves the system reusability and the flexibility issue, at the same time integrates power transactions operating system to other enterprise production systems. It proposes a valid solution for enterprise application integration in the heterogeneous environment at the technical level.
Suppression of NF-κB Reduces Myocardial No-Reflow
Min Zeng, Hongbing Yan, Yi Chen, Han-jun Zhao, Yuan Lv, Cheng Liu, Peng Zhou, Bo Zhao
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0047306
Abstract: No-reflow phenomenon is a risk factor which severely compromises the benefits of coronary revascularization in patients with acute myocardial infarction. Inflammatory response, as an essential component of cardiac ischemia/reperfusion (I/R) injury, has been suggested to contribute to the myocardial no-reflow. Since nuclear factor kappa B (NF-κB) is a key mediator of inflammation, we reasoned that inhibition of NF-κB might reduce the extent of no-reflow. To test this hypothesis, the left circumflex coronary arteries of New Zealand white male rabbits were ligated for 1.5 h, followed by reperfusion for 1 h to induce I/R injury. Pretreatment of the rabbits with a specific NF-κB inhibitor, pyrrolidine dithiocarbamate (PDTC), significantly attenuated neutrophil infiltration in the no-reflow area as well as the expansion of no-reflow. These beneficial effects were associated with a marked reduction in the serum levels of myocardial induced I/R tumor necrosis factor-α (TNF-α), intercellular adhesion molecule-1 (ICAM-1), and CXCL16. Consistently, simulative I/R culture of human umbilical vein endothelial cells (HUVECs) resulted in an increase of TNF-α, ICAM-1 and CXCL16, and all of these changes were significantly suppressed by pretreatment of the cells with PDTC or with siRNA-mediated p65 knockdown. Our data thus suggest that inhibition of NF-κB may reduce I/R-associated myocardial no-reflow through reduction of myocardial inflammation.
SnCl2/TiCl3-Mediated Deoximation of Oximes in an Aqueous Solvent
Mei-Huey Lin,Han-Jun Liu,Cheng-Yu Chang,Wei-Cheng Lin,Tsung-Hsun Chuang
Molecules , 2012, DOI: 10.3390/molecules17032464
Abstract: A simple procedure for SnCl2/TiCl3-mediated deoximation of ketoximes in an aqueous solvent is reported. Under the conditions developed in this effort, various ketones and aldehydes are produced in good to excellent yields.
Page 1 /76722
Display every page Item

Copyright © 2008-2017 Open Access Library. All rights reserved.