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Search Results: 1 - 10 of 2422 matches for " Hair dye poisoning "
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Thrombocytopenia, an Overlooked Hematological Derangement in Hair Dye Poisoning  [PDF]
Rizwan Naseer, AliRaza Ghani
Case Reports in Clinical Medicine (CRCM) , 2015, DOI: 10.4236/crcm.2015.48055
Abstract: Thrombocytopenia is a common hematological disorder characterized by abnormally low number of platelets in circulating blood from multiple causes. The fundamental mechanisms involved are: ineffective production of platelets by the bone marrow, accerlated destruction of platelets or platelet splenic sequestration. Hair dye, containing Paraphenyllinediamaine has been linked to allergic reaction, nephrotoxicity, mutagenicity and hematological derangements as anemia. A female showed a clinical spectrum of decreasing platelet count along with anemia due to oral ingestion of hair dye. It is important to consider thrombocytopenia in management plan as it may impact the clinical outcome.
HAIR DYE POISONING (AN EMERGING EMERGENCY FOR AIRWAY SURGEON- A CASE REPORT)
Karthikeyan Arjunan,Yahiah Basith,Balasubramanian Thiagarajan
Otolaryngology Online Journal , 2013,
Abstract: Super-Vasmol, a cheap, freely-available hair dye is emerging as a major cause of suicidal poisoning in India. It contains potential toxins including paraphenylene diamine, resorcinol, sodium ethylenediaminetetraacetic acid and propylene glycol which can result in multiorgan dysfunction2 .This case report is an attempt to throw light on this emerging problem.
HAIR DYE- AN EMERGING SUICIDAL AGENT: OUR EXPERIENCE
Mary Nirmala Suganthakumar,Ganesh R
Otolaryngology Online Journal , 2012,
Abstract: Hair dye poisoning has been emerging as one of the important causes of intentional deliberate self harm. To study the epidemiology of patients who consumed Super Vasmol (a commonly used commercial hair dye), profile of patients referred to the ENT department, to find the effectiveness of supportive therapy and to compare between the tracheostomy and the non tracheostomy group, a retrospective study was conducted in patients who consumed Super Vasmol admitted over a year (April 2009 – March 2010) in a teaching hospital in South India. Out of the 108 patients 38 (35.2%) were males and 70 (64.8%) were females. 42 (38.9%) were in 21-25 age group. Patients who developed cervico-facial oedema, throat pain, burning sensation in the throat, change of voice, no voice and dyspnoea with stridor were referred to the ENT Department. 74 (68.5%) patients needed an ENT opinion. Cervico-facial oedema was the main clinical manifestation in 74 patients. 33 of them underwent tracheostomy. The mortality in 108 patients was 22.2% and after tracheostomy 21.2%. Purpose of the study is to create public awareness about the lethal effects of the hair dye, because it is a major health problem and to educate the public and the medical professional about the need for aggressive and early treatment.
Hair dye poisoning and the developing world
Sampathkumar Krishnaswamy,Yesudas Sooraj
Journal of Emergencies, Trauma and Shock , 2009,
Abstract: Hair dye poisoning has been emerging as one of the important causes of intentional self harm in the developing world. Hair dyes contain paraphenylene-diamine and a host of other chemicals that can cause rhabdomyolysis, laryngeal edema, severe metabolic acidosis and acute renal failure. Intervention at the right time has been shown to improve the outcome. In this article, we review the various manifestations, clinical features and treatment modalities for hair dye poisoning.
Nephrogenic systemic fibrosis following hair-dye ingestion induced acute renal failure
Reddy I,Somani V,Swarnalata G,Maitra Sanjay
Indian Journal of Dermatology, Venereology and Leprology , 2010,
Abstract: We report a patient who developed acute renal failure following the ingestion of a hair-dye with a suicidal intent. He was managed by hemodialysis and other symptomatic measures. He developed generalized seizures and underwent MRI scan of the brain using gadolinium containing contrast material followed by development of bilateral and symmetrical thickening and induration of the skin over the extremities and verrucous papules and plaques over the lower back. Skin biopsy and immunohistochemistry showed typical features of nephrogenic fibrosing dermopathy as well as deposits of calcium. Successful management of renal failure resulted in clearing of all skin lesions except a small bony hard plate like area overt the left leg, the biopsy of which showed features of osseous metaplasia.
Development of a Novel Penetration-Enhancing Agent for Hair Products  [PDF]
Teruaki Nagasawa,Hiroyuki Suzuki,Masako Koyama,Toshiko Sato
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2013, DOI: 10.4236/jcdsa.2013.31020
Abstract: HAIRCARECUBETM (HCC) is a new additive for hair products that allows the active ingredient to penetrate into the hair. During the course of percutaneous absorption studies, we discovered that lyotropic liquid crystal promotes the skin’s absorptiveness to medicines. We conducted a study to determine whether or not lyotropic liquid crystal could be applied as a penetration-enhancing agent in hair, and as a result we have succeeded in developing HCC. In place of hair dye, we used fluorescein-HCC to evaluate hair permeability, and strong fluorescence was observed as deep as the core of the hair. Moreover, the strength of the fluorescence was dependent on HCC concentration. This result did not change under acidic or basic conditions. In addition, the same trends were observed when using an oxidative hair dye. Furthermore, when HCC was used together with hydrolyzed keratin, which repairs hair damage, a stronger restorative effect was observed. These results confirmed that HCC has the effect of promoting the permeation of pigments and other active ingredients into hair. HCC is expected to be very useful as an additive for developing functional cosmetic hair products.
Development of a Novel Penetration-Enhancing Agent for Hair Products  [PDF]
Teruaki Nagasawa, Hiroyuki Suzuki, Masako Koyama, Toshiko Sato, Kimio Kawamura, Yoko Yamaguchi
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2013, DOI: 10.4236/jcdsa.2013.31020
Abstract:

HAIRCARECUBETM (HCC) is a new additive for hair products that allows the active ingredient to penetrate into the hair. During the course of percutaneous absorption studies, we discovered that lyotropic liquid crystal promotes the skin’s absorptiveness to medicines. We conducted a study to determine whether or not lyotropic liquid crystal could be applied as a penetration-enhancing agent in hair, and as a result we have succeeded in developing HCC. In place of hair dye, we used fluorescein-HCC to evaluate hair permeability, and strong fluorescence was observed as deep as the core of the hair. Moreover, the strength of the fluorescence was dependent on HCC concentration. This result did not change under acidic or basic conditions. In addition, the same trends were observed when using an oxidative hair dye. Furthermore, when HCC was used together with hydrolyzed keratin, which repairs hair damage, a stronger restorative effect was observed. These results confirmed that HCC has the effect of promoting the permeation of pigments and other active ingredients into hair. HCC is expected to be very useful as an additive for developing functional cosmetic hair products.

Dermatología estética a través del tiempo
López Agüero,L C; Stella,A M;
Revista argentina de dermatolog?-a , 2007,
Abstract: anthropologists and archeologists have traced the evolution of skin care since prehistory. the human concern for his aesthetic appearance dates since the beginning of humanity. through time, more and more efficient formulations were looked for to extend youthfulness and beauty. an aesthetic skin has always been synonymous with health and at the present time the dermatologist has many resources to improve and acentuate the good quality of the skin.
Some in vitro and in vivo Pharmacological Observations on
Paraphenylene Diamine (Hair Dye)

Haseeba A. Saad,Badreldin H. Ali,Hassan M. Moussa,Mohammed B. Ali
Pakistan Journal of Biological Sciences , 2000,
Abstract: Objectives: Paraphenylene diamine (PPD) is commonly used in our region as hair dye, and to itensify Henna color. Several cases of poisoning with this compound have been reported. Therefore, we have examined the actions of PPD on a variety of pharmacological preparations in an attempt to determine the basis of its toxicity. Methods: Several isolated rat, rabbit, frog and Guinea pig preparations were used, together with anesthetized cat for blood pressure measurement. Results: After incubation of PPD with chopped G. Pig lung tissue, the supernatant was found to contract G. Pig illeum. This action was abolished by chlorpheniramine, suggesting that PPD released histamine. PPD, or the chopped lung tissue preparation, given alone, did not contract G. Ileum. Various doses of PPD did not affect striated muscle preparations, nor did it affect isolated tissues preparation, given alone, did not contract G. Ilenum. Various doses of PPD was also without effect on prostaglandin syntheis or receptors. No significant change in blood pressure was observed following PPD injection at low doses in anaesthetized cats, whereas high doses were lethal. Conclusion: PPD was ineffective in significantly altering the reactivity of several pharmacological preparations. It suggested the PPD releases histamine.
Obstrucción aguda de la vía respiratoria superior y rabdomiolisis luego de intoxicación por tintura para el cabello
QUEVEDO,AUGUSTO; ARROYAVE,CLAUDIA;
Iatreia , 2004,
Abstract: there have been few cases reported of intoxication by hair dyes in antioquia; however, their toxicity may be potentially lethal when their components enter the organism by oral route inducing a multiorganic compromise that may lead to death. we report the case of a two year old girl who ingested 125mg/kg of paraphenylenediamine, with boric acid and sodium perborate; these compounds are part of the commercial presentation of a hair dye; the child suffered airway obstruction because of angioedema that required intubation, ventilatory support, steroids and antihistaminics; due to the airway involvement the patient presented acute pulmonary edema and subsequently pneumonia that required antibioticotherapy. additionally, she had severe rhabdomyolysis that was treated with adequate fluid administration to avoid alterations in renal function. she remained at hospital for ten days and was discharged in good condition. we review the possible pathophysiologic mechanisms, the clinical manifestations and the treatment of paraphenylenediamine intoxication because this compound was the most important cause of the clinical manifestations of our patient.
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