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Search Results: 1 - 10 of 61467 matches for " Haifeng Yu "
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Photoresponsive Block Copolymers Containing Azobenzenes and Other Chromophores
Haifeng Yu,Takaomi Kobayashi
Molecules , 2010, DOI: 10.3390/molecules15010570
Abstract: Photoresponsive block copolymers (PRBCs) containing azobenzenes and other chromophores can be easily prepared by controlled polymerization. Their photoresponsive behaviors are generally based on photoisomerization, photocrosslinking, photoalignment and photoinduced cooperative motions. When the photoactive block forms mesogenic phases upon microphase separation of PRBCs, supramolecular cooperative motion in liquid-crystalline PRBCs enables them to self-organize into hierarchical structures with photoresponsive features. This offers novel opportunities to photocontrol microphase-separated nanostructures of well-defined PRBCs and extends their diverse applications in holograms, nanotemplates, photodeformed devices and microporous films.
Quantify single nucleotide polymorphism (SNP) ratio in pooled DNA based on normalized fluorescence real-time PCR
Airong Yu, Haifeng Geng, Xuerui Zhou
BMC Genomics , 2006, DOI: 10.1186/1471-2164-7-143
Abstract: In our method, initial reaction background fluorescence was determined based upon fitting of raw fluorescence data to four-parametric sigmoid function. After that, each fluorescence data point was first subtracted by respective background fluorescence and then each subtracted fluorescence data point was divided by the specific background fluorescence to get normalized fluorescence. By relating the normalized fluorescence ratio to the premixed known allele ratio of two alleles in standard samples, standard linear regression equation was generated, from which unknown specimens allele ratios were extrapolated using the measured normalized fluorescence ratio. In this article, we have compared the results of the proposed method with those of baseline subtracted fluorescence ratio method and conventional Ct method.Results demonstrated that the proposed method could improve the reliability, precision, and repeatability for quantifying allele ratios. At the same time, it has the potential of fully automatic allelic ratio quantification.Single nucleotide polymorphisms (SNPs), the most common source of polymorphism in the human genome, have a wide applications in human genetics, pharmacogenomics, analysis of clinical samples, and identification of human susceptibility genes involved in complex diseases [1-4]. Pooling equal amounts of DNA from all the individual samples and typing one SNP marker at a time can save valuable template DNA and has been successfully utilized in microsatellite markers [5] and SNPs [6,7]. Thus, a quantifying SNPs method in pooled and mixed DNA samples with high precision and efficiency is required in human genetics [8]. Another demand of quantifying SNPs in pooled DNA samples lies in the study of population dynamics of pathogens, from which quantifying SNP frequencies may not only help monitor the pathogen dynamics associated with treatment but could also improve therapeutic decision making [9]. Several genotyping methods were found to be suitable fo
On Differentially Private Online Collaborative Recommendation Systems
Seth Gilbert,Xiao Liu,Haifeng Yu
Computer Science , 2015,
Abstract: In collaborative recommendation systems, privacy may be compromised, as users' opinions are used to generate recommendations for others. In this paper, we consider an online collaborative recommendation system, and we measure users' privacy in terms of the standard differential privacy. We give the first quantitative analysis of the trade-offs between recommendation quality and users' privacy in such a system by showing a lower bound on the best achievable privacy for any non-trivial algorithm, and proposing a near-optimal algorithm. From our results, we find that there is actually little trade-off between recommendation quality and privacy for any non-trivial algorithm. Our results also identify the key parameters that determine the best achievable privacy.
Review on Drag Reduction and Its Heat Transfer by Additives
Yi Wang,Bo Yu,Jacques L. Zakin,Haifeng Shi
Advances in Mechanical Engineering , 2011, DOI: 10.1155/2011/478749
Abstract: Since its discovery more than 60 years ago, the drag reduction phenomenon has achieved many notable energy saving effects. These achievements have encouraged researchers to study drag reduction further and further so that it can be utilized better. But due to the complex characteristics of turbulent flow, recent theories cannot explain all the phenomena of drag reduction. To give an overview of drag reduction and corresponding heat transfer for further understanding, this paper summarizes the main advancements of drag reduction during these 60 years, including background, application, development, theory, and research methods of different drag reducers. Future directions of development are also discussed.
Video Transmission over MIMO-OFDM System: MDC and Space-Time Coding-Based Approaches
Haifeng Zheng,Congchong Ru,Chang Wen Chen,Lun Yu
Advances in Multimedia , 2007, DOI: 10.1155/2007/61491
Abstract: MIMO-OFDM is a promising technique for the broadband wireless communication system. In this paper, we propose a novel scheme that integrates multiple-description coding (MDC), error-resilient video coding, and unequal error protection strategy with hybrid space-time coding structure for robust video transmission over MIMO-OFDM system. The proposed MDC coder generates multiple bitstreams of equal importance which are very suitable for multiple-antennas system. Furthermore, according to the contribution to the reconstructed video quality, we apply unequal error protection strategy using BLAST and STBC space-time codes for each video bitstream. Experimental results have demonstrated that the proposed scheme can be an excellent alternative to achieve desired tradeoff between the reconstructed video quality and the transmission efficiency.
IL-17 and IL-22 in Cerebrospinal Fluid and Plasma Are Elevated in Guillain-Barré Syndrome
Shujuan Li,Ming Yu,Haifeng Li,Hongliang Zhang,Yanfang Jiang
Mediators of Inflammation , 2012, DOI: 10.1155/2012/260473
Abstract: Guillain-Barré syndrome (GBS) is an acute autoimmune-mediated inflammatory demyelinating disease that causes rapidly progressing paralysis and occasionally respiratory failure. We hypothesized that interleukin (IL)-17 and IL-22 are elevated in GBS and participate in the autoimmune inflammatory response of GBS. We used sandwich enzyme-linked immunosorbent assay (ELISA) to measure the IL-17 and IL-22 levels in the CSF, and plasma from 22 GBS patients at the acute phase and 18 healthy controls (HC). The results show that CSF and plasma levels of IL-17 and IL-22 are elevated in GBS patients compared with HC. IL-17 and IL-22 levels in CSF, respectively, are correlated with GBS disability scale scores (GDSs). Meanwhile, IL-17 and IL-22 levels in CSF, IL-22 in CSF, and plasma of GBS patients have positive correlation, respectively. The increased levels of IL-17 and IL-22 in CSF may be explained by the disruption of blood-brain barrier (BBB) and peripheral nervous system (PNS) local inflammation in GBS. Meanwhile, the elevated levels of these two cytokines in plasma suggest the activation of Th17 and Th22 cells in the systemic immune response of GBS. Our data provide preliminary evidence that GBS is associated with high levels of IL-17 and IL-22 in CSF and plasma. These cytokines display pathogenic potential and may serve as useful biomarkers for GBS. 1. Introduction Guillain-Barré syndrome (GBS) is an acute autoimmune-mediated inflammatory demyelinating disease that affects the peripheral nerves involving myelin sheath and axons [1]. It is clinically characterized by rapidly progressing symmetrical weakness and hyporeflexia/areflexia followed mostly by recovery [1, 2]. The severity of weakness ranges from mild limb asthenia to absolute paralysis, occasionally with respiratory failure that may lead to death [1, 2]. Meanwhile, the cerebrospinal fluid (CSF) of GBS patients usually shows characteristic albumin-cytological dissociation, that is, elevated protein levels and approximately normal cell counts, from two weeks after the disease onset [2]. There is strong evidence proving that both humoral and cellular immune mechanisms are involved in the pathogenesis of GBS: (i) serum antibodies to various gangliosides in human peripheral nerves have been found in about half of GBS patients [3]; (ii) pathological findings in GBS include lymphocytic infiltration in spinal roots and peripheral nerves, followed by macrophage-mediated, multifocal stripping of myelin [4]; (iii) plasma exchange (PE) and intravenous immunoglobulin (IVIg) therapies are effective in the
Cerebral Falx Mature Teratoma with Rare Imaging in an Adult
Jingwei Zhao, Haifeng Wang, Jing Yu, Yanping Zhong, Pengfei Ge
International Journal of Medical Sciences , 2012,
Abstract: Intracranial mature teratoma is a rare lesion in adults. Despite several intracranial mature teratomas had been reported not to be located at the midline region, no one was found to be within cerebral falx. Herein, we reported a 37-year-old female patient with an intracranial mature teratoma confined within frontal cerebral falx. Her main complaint was intermitted headache, which could not be relieved recently by taking painkiller. Excepting for mild papilledema, we did not find positive neurological signs on physical examination. CT scanning showed it was a round homogenously hypodense lesion with hyperdense signal at its rim. MRI revealed the lesion was 3.5cm×3.6cm×4.5cm in volume, with uniformed hypointensity on T1WI, hyperintensity on T2WI and enhancement in the capsule. It was totally removed via inter-hemispheric approach, and we found the lesion was confined within the frontal cerebral falx. Postoperatively, it was proved histologically to be a mature teratoma. At three years of fellow up, neither neurological deficits nor recurrent sings on MRI was found. To our best knowledge, this is the first case of intracranial mature teratoma within cerebral falx.
Occurrence of selected aliphatic amines in source water of major cities in China
Haifeng Zhang,Shuoyi Ren,Jianwei Yu,Min Yang,
Haifeng Zhang
,Shuoyi Ren,Jianwei Yu,Min Yang

环境科学学报(英文版) , 2012,
Abstract: The formation of toxic nitrogenous disinfection byproducts (N-DBPs), such as nitrosamines, halonitromethanes and haloacetonitriles, from reactions between chlorine/chloramine and dissolved organic nitrogen in drinking water has caused great concern with regarding public health. This study revealed the occurrence of 17 aliphatic amines, some of which have been confirmed to be the precursors of N-DBPs, in source water across China. A sensitive method based on benzenesulfonyl chloride derivatization and liquid-liquid extraction followed by GC-MS analysis was established for the simultaneous analysis of the selected amines in aqueous samples. In total, 37 source water samples from the capital cities of 20 provinces were collected for the survey. Among the 17 amines, 14 were detected with an average frequency of detection of 36%. The most relevant amines in terms of frequency and maximum concentrations detected were dimethylamine (100%, 24.82 μg/L), methylamine (78%, 0.92 μg/L), N-methylethylamine (70%, 8.84 μg/L), propylamine (59%, 10.69 μg/L), diethylamine (54%, 3.76 μg/L), N-methylbutylamine (35%, 3.07 μg/L), N-ethylpropylamine (35%, 0.52 μg/L), and piperidine (32%, 2.35 μg/L). This is the first large scale survey of the aliphatic amines occurrence in source water in the world. The wide presence of nitrosamine precursors like dimethylamine, N-methylethylamine and diethylamine, and the precursors of haloacetonitriles and halonitromethanes like methylamine and propylamine suggests that better source water management is required to ensure the safety of drinking water.
A Min-Conflict Heuristic-Based Web Service Chain Reconfiguration Approach  [PDF]
Haifeng Li, Xiaoxia Yang
Intelligent Information Management (IIM) , 2010, DOI: 10.4236/iim.2010.210068
Abstract: The state-of-art Web services composition approaches are facing more and more serious bottlenecks of effectiveness and stability with the increasing diversity and real-time requirements of applications, since new web service chain must be generated from “scratch” for each application. To break these bottlenecks, this paper presents a Min-Conflict Heuristic-Based Web Service Chain Reconfiguration Approach(MCHRC) to maximal reuse relative web services chain: a min-conflict heuristic based regression search algorithms is proposed to implement the web services chain reconfiguration based on the formal definition of process constraint and integrity constraint to guarantee the correctness and integrality of the reconfiguration. This benefits the service reuse and then can relieve the time complexity of web service composition and improve web services chain executing stability by reduce service provider load. Experimental results show that this approach makes significant improvement on the effectiveness of web services composition.
Expert Anti-Evaluation Model Based on Matter-Element Analysis in Fund Project Peer-Review System  [PDF]
Haifeng Li, Yanzhong Dang
Intelligent Information Management (IIM) , 2010, DOI: 10.4236/iim.2012.23027
Abstract: The article analyses several key issues which restrict the effectiveness of fund project peer review work. It analyses the evaluating theory and matter-element theory to access the expert anti-evaluation model, and also studies the expert anti-evaluation index system to support the anti-evaluation method. The practical basis is the true score data of the experts which is collected from the actual anti-evaluation in Liaoning province science and technology fund project peer review system. With the practical experience of the actual project, we prove that the expert index system anti-evaluation model and expert anti-evaluation method can improve the fund project peer review work and play a positive role for the peer review work and also make the review work more scientific and more rational.
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