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Antiamnesic potentiality of Argyreia speciosa (Burm.f) Boj. in mice
Habbu P,Mahadevan K,Shastry R,Chilakwad S
International Journal of Green Pharmacy , 2010,
Abstract: Several ′rasayana′ herbs that are enlisted in Indian system of medicine have been in use for the treatment of age-related neurodegenerative disorders including Alzheimer′s disease (AD). Roots of Argyreia speciosa are used in several Ayurvedic preparations as brain tonic and nervine tonic. The present work was undertaken to justify the traditional claim of the plant as nootropic and antiamnesic agent in mice. The ethyl acetate and ethanolic fractions (EtAS) of roots were selected for the study. Exteroceptive behavioural models such as elevated plus maze and Water maze were used to assess the short-term memory, whereas, scopolamine and natural ageing- induced amnesia served as interoceptive models. The whole brain acetyl cholinesterase activity was measured to assess the effect of A. speciosa on the central cholinergic system. Scopolamine (0.4 mg/kg, i.p.) increased the transfer latency significantly ( P< 0.01) in young mice on the first and second day as compared to control indicating the impairment of memory. Pretreatment with EAAS (100 and 200 mg/kg, p.o.) significantly ( P< 0.01) attenuated scopolamine and ageing-induced amnesia. Escape latency time was recorded in the water maze model as an index of acquisition, and trials were conducted for 4 days. The mean time spent in target quadrant (TSTQ) during retrieval trial on fifth day was taken as the index of retrieval (memory). EAAS (100 and 200 mg/kg, p.o.) administered before the training trial (from day 1 to day 4), significantly ( P< 0.01) attenuated scopolamine and ageing-induced decrease in TSTQ during the retrieval test on the fifth day. EAAS (100 and 200 mg/kg, p.o.) significantly produced reduction in whole brain acetyl cholinesterase (AChE) activity of both young and aged mice thus exhibiting anti-AChE activity in whole brain homogenate compared to Piracetam, scopolamine and control groups of mice. The results indicate that A. speciosa has significant nootropic and antiamnesic activity, justifying its traditional use in Ayurveda.
Trans-arterial hepatic radioembolisation of yttrium-90 microspheres
Murthy R,Habbu A,Salem R
Biomedical Imaging and Intervention Journal , 2006, DOI: 10.2349/biij.2.3.e43
Abstract:
Trans-arterial hepatic radioembolisation of yttrium-90 microspheres
R Murthy,A Habbu,R Salem
Biomedical Imaging and Intervention Journal , 2006, DOI: 10.2349/biij.2.3.e43
Abstract:
Protective effect of Habenaria intermedia tubers against acute and chronic physical and psychological stress paradigms in rats
Habbu, PV;Smita, DM;Mahadevan, KM;Shastry, RA;Biradar, SM;
Revista Brasileira de Farmacognosia , 2012, DOI: 10.1590/S0102-695X2012005000033
Abstract: the present study was undertaken to evaluate the adaptogenic activity of ethanol (ethi), ethyl acetate (eahi) fractions of habenaria intermedia d. don, orchidaceae (hi), tubers using immobilization induced acute stress (as), chronic stress (cs) and swimming induced stress in experimental animals. the tested doses of ethi (100 and 200 mg/kg, p.o.) and higher dose of eahi (200 mg/kg, p.o.) normalized altered serum biochemical parameters and the severity of ulcers in both as and cs. eahi and ethi restored the hyperthrophy of adrenal gland and atrophy of spleen and thymus gland in as and cs. greater swimming time was noted in the mice pretreated with ethi and eahi. levels of adrenal ascorbic acid and cortisol were restored significantly. eahi exhibited prominent scavenging effect of dpph, hydroxyl radical and lipid peroxidation in vitro. phytochemical studies resulted in the isolation of scopoletin and gallic acid as marker compounds. our results proved the traditional claim of hi as anti-stress/adaptogen in ayurvdea.
Protective effect of Habenaria intermedia tubers against acute and chronic physical and psychological stress paradigms in rats
PV Habbu,DM Smita,KM Mahadevan,RA Shastry
Revista Brasileira de Farmacognosia , 2012,
Abstract: The present study was undertaken to evaluate the adaptogenic activity of ethanol (EtHI), ethyl acetate (EAHI) fractions of Habenaria intermedia D. Don, Orchidaceae (HI), tubers using immobilization induced acute stress (AS), chronic stress (CS) and swimming induced stress in experimental animals. The tested doses of EtHI (100 and 200 mg/kg, p.o.) and higher dose of EAHI (200 mg/kg, p.o.) normalized altered serum biochemical parameters and the severity of ulcers in both AS and CS. EAHI and EtHI restored the hyperthrophy of adrenal gland and atrophy of spleen and thymus gland in AS and CS. Greater swimming time was noted in the mice pretreated with EtHI and EAHI. Levels of adrenal ascorbic acid and cortisol were restored significantly. EAHI exhibited prominent scavenging effect of DPPH, hydroxyl radical and lipid peroxidation in vitro. Phytochemical studies resulted in the isolation of scopoletin and gallic acid as marker compounds. Our results proved the traditional claim of HI as anti-stress/adaptogen in Ayurvdea.
太古宙绿岩带金矿区域预测准则
д.в.Pундцвист
黄金科学技术 , 1991,
Abstract:
Land Use and Land Cover Changes in a Tropical River Basin: A Case from Bharathapuzha River Basin, Southern India  [PDF]
P. P. Nikhil Raj, P. A. Azeez
Journal of Geographic Information System (JGIS) , 2010, DOI: 10.4236/jgis.2010.24026
Abstract: A study of the spatial and temporal changes in land use and land cover (LULC) was conducted using Remote Sensing and GIS. We analyzed the LULC of Bharathapuzha river basin, south India using multispectral LANDSAT imageries of 1973-2005 time periods. 31% depletion in the natural vegetation cover and 8.7% depletion in wetland agriculture area were seen in the basin during the period. On the other hand the urban spread in the basin increased by 32%. The study highlights the need for a scientific management plan for the sustainability of the river basin, keeping in view the recent climatic anomalies and hydrological conditions of the basin.
Morphometric Analysis of a Tropical Medium River System: A Case from Bharathapuzha River Southern India  [PDF]
P. P. Nikhil Raj, P. A. Azeez
Open Journal of Modern Hydrology (OJMH) , 2012, DOI: 10.4236/ojmh.2012.24011
Abstract: Baseline morphometric information at a sub basin level is essential to develop appropriate strategy for sustainable, socially acceptable, ecologically benign and economically viable development of a river basin. The present study was carried out in one of the less studied Bharathapuzha river basin (BRB), the second longest river in the state of Kerala, India. The annual discharge of the river is 3.94 km3. Nevertheless the basin, which receives about 1828 mm of annual rainfall, in recent years has been facing dearth of water. We used GIS and RS tools to study the morphometric characteristics of the basin. The seventh order main river is formed by several lower order streams forming a dentritic flow pattern. Basin geology, slope and rainfall pattern in the basin determine the morphometric characteristics of the basin. The linear aspects of the basin including stream length ratio and bifurcation ratio indicate the role of relief in the basin while the areal ratios indicate the elongate nature of the basin.
Dielectric Property Studies of Biologically Compatible Brushite Single Crystals Used as Bone Graft Substitute  [PDF]
M. P. Binitha, P. P. Pradyumnan
Journal of Biomaterials and Nanobiotechnology (JBNB) , 2013, DOI: 10.4236/jbnb.2013.42016
Abstract:

The electrical characterization of bone is essential for the better understanding of the role of electrical stimulation in bone remodeling. Calcium Hydrogen Phosphate Dihydrate or brushite (CaHPO4 2H2O) has been used in bone substitution owing to their fast resorption under physiological condition. Brushite is a suitable matrix for osteoconductive bone grafts. In this work, Calcium Hydrogen Phosphate single crystals have been grown by single diffusion gel growth technique. The powder XRD studies revealed the monoclinic structure of the grown crystals. The vibrational analysis of the crystals is done with FTIR spectroscopy and the major functional groups and their assigned vibrations are discussed. The frequency dependence of dielectric constant and ac conductivity at different temperatures have been studied in detail. This study shows decrease in the dielectric constant with the increase in frequency and temperature. The variation of ac conductivity is found to be increasing with frequency and decreasing with temperature.

How to Introduce the Basis of Algorithmics? Thanks to the Enumeration and Composition of All Riffle Shuffles from a N Card Deck Used in MathMagic  [PDF]
P. Schott
Creative Education (CE) , 2012, DOI: 10.4236/ce.2012.34082
Abstract: Why use magic for teaching combinatory, algorithms and finally informatics basis as tables, control structure, loops and recursive function? Magicians know that once the surprise has worn off, the audience will seek to understand how the trick works. The aim of every teacher is to interest their students, and a magic trick will lead them to ask ‘how?’ and ‘why?’ and ‘how can I create one myself?’ In this article we consider a project I presented in 2009, the subject of which was ‘How many riffle shuffles does exist from a N card deck? Find the composition of each possible riffle shuffle’. The aim of the paper is not only to describe the project scope, the students’ theoretical studies, their approach to this problem and their computer realizations, but also to give ideas for a course or project using pedagogy. That is why only remarkable students’ realizations are shown. In order to complete the given project, the students must answer three steps: the first one is to answer to the following question: “how can I find all possible riffle shuffles with few cards? (for exe*ample 3, 4 or 5 cards) the second one (to go further ) is to answer to the following question “how can I generalize this solution through an algorithm?” the last one (to obtain the results!) is to program the algorithm with a recursive and a non-recursive solution). Each step of the Matlab? solution code is associated with an informatics basis. Whatever the student's professional ambitions, they will be able to see the impact that originality and creativity have when combined with an interest in one’s work. That’s why, two ameliorations of the ‘basic’ algorithm are proposed and a study of the gain thanks to these ameliorations is done. The students know how to “perform” a magic trick for their family and friends thanks to the use of riffle shuffle in Gilbreath’s principles, a trick that they will be able to explain and so enjoy a certain amount of success with. Sharing a mathematical/informatics demonstration is not easy and the fact that they do so means that they will have worked on and understood and are capable of explaining this knowledge. Isn’t this the aim of all teaching?
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