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Search Results: 1 - 10 of 39689 matches for " HE Gan-Xiang "
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Treatment of nodular vasculitis based on syndrome differentiation: A report of 32 cases
HE Gan-Xiang
Zhong Xi Yi Jie He Xue Bao , 2003,
Abstract:
Microarray-based gene expression profiles of silkworm brains
Ling Gan, Xilong Liu, Zhonghuai Xiang, Ningjia He
BMC Neuroscience , 2011, DOI: 10.1186/1471-2202-12-8
Abstract: We reported microarray-based gene expression profiles in silkworm brains at four stages including V7, P1, P3 and P5. A total of 4,550 genes were transcribed in at least one selected stage. Of these, clustering algorithms separated the expressed genes into stably expressed genes and variably expressed genes. The results of the gene ontology (GO) and Kyoto encyclopedia of genes and genomes (KEGG) analysis of stably expressed genes showed that the ribosomal and oxidative phosphorylation pathways were principal pathways. Secondly, four clusters of genes with significantly different expression patterns were observed in the 1,175 variably expressed genes. Thirdly, thirty-two neuropeptide genes, six neuropeptide-like precursor genes, and 117 cuticular protein genes were expressed in selected developmental stages.Major characteristics of the transcriptional profiles in the brains of Bombyx mori at specific development stages were present in this study. Our data provided useful information for future research.The silkworm, Bombyx mori, is a holometabolous insect that has four distinct life stages including embryo, larva, pupa, and moth. It is a model organism for Lepidoptera in molecular genetics and functional genomics and has greatly contributed to understanding of the mechanisms governing metamorphosis and diapause [1]. Lepidoptera represent a diverse group of agricultural insect pests of food and fiber crops worldwide. Hence, gaining a thorough understanding of gene function in Lepidoptera is a critical step when developing new and targeted methods of pest control. The insect brain is a 'supraesophageal ganglion' which is interconnected by paired circumesophageal connectives with subesophageal ganglion(SG)[2]. The insect brain is an important part of neurosecretory system. A large number of neuropeptide precursor genes have been characterized in insect brains [3]. As their major secreted molecules, neuropeptides play multiple functions. Brain neuropeptides are mainly use
Preparation and Performance of (RuO2/Co3O4)·nH2O Composite Films in Super Capacitor
GAN Wei-Ping, MA He-Ran, LI Xiang
无机材料学报 , 2011, DOI: 10.3724/sp.j.1077.2011.00823
Abstract: The (RuO2/Co3O4)·nH2O composite films electrode used in super capacitor was prepared from isopropanol solution of RuCl3·3H2O and Co(CH3COO)2 by in―situ thermal decomposition. The micro― morphology, phase transformation and electrochemical properties were studied by scanning electron microscope, XRD, infrared spectrometer and electrochemical method, respectively. The results show that, the composite films with n(Rn3+): n(Co2+)=1:3 exhibit the best performances after heat treatment at 260 for 3h. The specific capacitance and adhesive force of the composite films are 569F/g and 22.4MPa, respectively. The internal resistance of the composite films is only 0.42Ω and its specific capacitance keep 97.6% of initial capacitance after over 1000 charge―discharge cycles.
Characterization and Electrochemical Properties of RuO2 Film Electrode on the Inner-wall of Tantalum Shell for Capacitor
GAN Wei-Ping, LIU Ji-Yu, LIU Hong, LI Xiang, MA He-Ran
无机材料学报 , 2010, DOI: 10.3724/sp.j.1077.2010.00882
Abstract: Using the methods of coated and thermal decomposed ruthenium chloride, the RuO2 thin film was synthesized on the inner-wall surface of tantalum shell. Its morphology and structure were characterized by scanning electron microscope and X-ray diffraction. The electrochemical performances of the RuO2 thin film electrode were tested by cyclic voltammetry, galvanostatic charging/discharging and electrochemical impedance spectroscope. The results show that the RuO2 thin film calcinated at 280 as amorphous structure and the specific capacitance of the electrode is 212F/g (in 0.5 mol/L H2SO4 electrolyte) with good electrochemical performance. When the films are assembled into ST3 type 60 V 330 μF tantalum capacitors, the capacitance can still maintain 345μF after celaring and electrical aging. The equivalent series resistance (ESR) is less than 1Ω and the leakage current is less than10μA.
Exendin-4 Protects Mitochondria from Reactive Oxygen Species Induced Apoptosis in Pancreatic Beta Cells
Zhen Li, Zhiguang Zhou, Gan Huang, Fang Hu, Yufei Xiang, Lining He
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0076172
Abstract: Objective Mitochondrial oxidative stress is the basis for pancreatic β-cell apoptosis and a common pathway for numerous types of damage, including glucotoxicity and lipotoxicity. We cultivated mice pancreatic β-cell tumor Min6 cell lines in vitro and observed pancreatic β-cell apoptosis and changes in mitochondrial function before and after the addition of Exendin-4. Based on these observations, we discuss the protective role of Exendin-4 against mitochondrial oxidative damage and its relationship with Ca2+-independent phospholipase A2. Methods We established a pancreatic β-cell oxidative stress damage model using Min6 cell lines cultured in vitro with tert-buty1 hydroperoxide and hydrogen peroxide. We then added Exendin-4 to observe changes in the rate of cell apoptosis (Annexin-V-FITC-PI staining flow cytometry and DNA ladder). We detected the activity of the caspase 3 and 8 apoptotic factors, measured the mitochondrial membrane potential losses and reactive oxygen species production levels, and detected the expression of cytochrome c and Smac/DLAMO in the cytosol and mitochondria, mitochondrial Ca2-independent phospholipase A2 and Ca2+-independent phospholipase A2 mRNA. Results The time-concentration curve showed that different percentages of apoptosis occurred at different time-concentrations in tert-buty1 hydroperoxide- and hydrogen peroxide-induced Min6 cells. Incubation with 100 μmol/l of Exendin-4 for 48 hours reduced the Min6 cell apoptosis rate (p<0.05). The mitochondrial membrane potential loss and total reactive oxygen species levels decreased (p<0.05), and the release of cytochrome c and Smac/DLAMO from the mitochondria was reduced. The study also showed that Ca2+-independent phospholipase A2 activity was positively related to Exendin-4 activity. Conclusion Exendin-4 reduces Min6 cell oxidative damage and the cell apoptosis rate, which may be related to Ca2-independent phospholipase A2.
Identification of target genes of transcription factor activator protein 2 gamma in breast cancer cells
He Ailan, Xiao Xiangwen, Ren Daolong, Gan Lu, Ding Xiaofeng, Qiao Xi, Hu Xingwang, Liu Rushi, Zhang Jian, Xiang Shuanglin
BMC Cancer , 2009, DOI: 10.1186/1471-2407-9-279
Abstract: To identify the gene targets that mediate its effects, we performed chromatin immunoprecipitation (ChIP) to isolate AP-2γ binding sites on genomic DNA from human breast cancer cell line MDA-MB-453.20 novel DNA fragments proximal to potential AP-2γ targets were obtained. They are categorized into functional groups of carcinogenesis, metabolism and others. A combination of sequence analysis, reporter gene assays, quantitative real-time PCR, electrophoretic gel mobility shift assays and immunoblot analysis further confirmed the four AP-2γ target genes in carcinogenesis group: ErbB2, CDH2, HPSE and IGSF11. Our results were consistent with the previous reports that ErbB2 was the target gene of AP-2γ. Decreased expression and overexpression of AP-2γ in human breast cancer cells significantly altered the expression of these four genes, indicating that AP-2γ directly regulates them.This suggested that AP-2γ can coordinate the expression of a network of genes, involving in carcinogenesis, especially in breast cancer. They could serve as therapeutic targets against breast cancers in the future.The transcription factor activator protein-2 (AP-2) family consists of AP-2α, AP-2β, AP-2γ, AP-2δ and AP-2ε; they are retinoic acid inducible and developmentally regulated [1-6]. The AP-2 protein forms a unique modular structure containing an N-terminal proline- and glutamine-rich transactivational domain and a complex C-terminal helix-span-helix motif necessary and sufficient for dimerization and site-specific DNA binding. Through binding to a GC-rich recognition sequence in the regulatory regions of many genes, AP-2 protein provides a fundamental mechanism for regulating gene expression and involving into lots of cellular processes [7,8]. AP-2 proteins have been demonstrated to participate in the regulation of various signaling pathways during development, cell growth, differentiation and apoptosis by mouse knock-out studies [9-15]. AP-2 proteins are also essential for maintaining cel
Research on the ultraweak photon emission from anti-cancer plants  [PDF]
Ping Wu, Xiang He
Journal of Biomedical Science and Engineering (JBiSE) , 2009, DOI: 10.4236/jbise.2009.23026
Abstract: UPE (Ultraweak photon emission) is one kind of a common phenomenon in biological organisms. It contains a wealth of information of biological functions. In this paper, single photon counting system is used to measure UPE of some anti- cancer herbal plants. For the plants, the changes of UPE under different water condition are stud-ied and the varying laws of ultraweak photon number with time are analysed. The results are higher fit double exponential decay law.
Identity Authentication Based on Two-Beam Interference  [PDF]
Wenqi He, Xiang Peng
Journal of Computer and Communications (JCC) , 2014, DOI: 10.4236/jcc.2014.24005
Abstract:

A two-factor identity authentication method on the basis of two-beam interference was presented. While verifying a user’s identity, a specific “phase key” as well as a corresponding “phase lock” are both mandatory required for a successful authentication. Note that this scheme can not only check the legality of the users, but also verify their identity levels so as to grant them hierarchical access permissions to various resources of the protected systems or organizations. The authentication process is straightforward and could be implemented by a hybrid optic-electrical system. However, the system designing procedure involves an iterative Modified Phase Retrieval Algorithm (MPRA) and can only be achieved by digital means. Theoretical analysis and simulations both validate the effectiveness of our method.

Two-Dimensional Heteroscedastic Discriminant Analysis for Facial Gender Classification
Junying Gan,Sibin He
Computer and Information Science , 2009, DOI: 10.5539/cis.v2n4p169
Abstract: In this paper, a novel discriminant analysis named two-dimensional Heteroscedastic Discriminant Analysis (2DHDA) is presented, and used for gender classification. In 2DHDA, equal within-class covariance constraint is removed. Firstly, the criterion of 2DHDA is defined according to that of 2DLDA. Secondly, the criterion of 2DHDA, log and rearranging terms are taken, and then the optimal projection matrix is solved by gradient descent algorithm. Thirdly, face images are projected onto the optimal projection matrix, thus the 2DHDA features are extracted. Finally, Nearest Neighbor classifier is selected to perform gender classification. Experimental results show that higher recognition rate is obtained by way of 2DHDA compared with 2DLDA and HDA.
Non-integrability of dominated splitting on $\mathbb{T}^2$
Baolin He,Shaobo Gan
Mathematics , 2014, DOI: 10.1088/0951-7715/27/12/3179
Abstract: We construct a diffeomorphism $f$ on 2-torus with a dominated splitting $E \oplus F$ such that there exists an open neighborhood $\mathcal{U} \ni f$ satisfying that for any $g \in \mathcal{U}$, neither $E_g$ nor $F_g$ is integrable.
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