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Search Results: 1 - 10 of 149981 matches for " H. Coskun "
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Histamine Contents of Some Commercial Vegetable Pickles
K. Ekici,H. Coskun
Pakistan Journal of Nutrition , 2004,
Abstract: Histamine contents of some pickles were aimed to determine in this survey, and 50 samples of vegetable pickles (of 28 as mixed, 6 as hot pepper and 7 as cucumber pickles) were collected from market in Van city. Histamine determination was done by fluorometric method. It was found that the levels of histamine for all pickles were changed between 16.54 and 74.91 mg kg-1 (average 30.73 mg kg-1). The maximum value (74.91 mg kg-1) was obtained from a sample of hot pepper pickles. All values are below the level of 1000 mg kg-1, which is the minimal level for clinical symptoms of toxicity.
Analysis of Land Use Change and Urbanization in the Kucukcekmece Water Basin (Istanbul, Turkey) with Temporal Satellite Data using Remote Sensing and GIS
H. Gonca Coskun,Ugur Alganci,Gokce Usta
Sensors , 2008, DOI: 10.3390/s8117213
Abstract: Accurate and timely information about land use and land cover (LULC) and its changes in urban areas are crucial for urban land management decision-making, ecosystem monitoring and urban planning. Also, monitoring and representation of urban sprawl and its effects on the LULC patterns and hydrological processes of an urbanized watershed is an essential part of water resource planning and management. This paper presents an image analysis study using multi temporal digital satellite imagery of LULC and changes in the Kucukcekmece Watershed (Metropolitan Istanbul, Turkey) from 1992 to 2006. The Kucukcekmece Basin includes portions of the Kucukcekmece District within the municipality of Istanbul so it faces a dramatic urbanization. An urban monitoring analysis approach was first used to implement a land cover classification. A change detection method controlled with ground truth information was then used to determine changes in land cover. During the study period, the variability and magnitude of hydrological components based on land-use patterns were cumulatively influenced by urban sprawl in the watershed. The proposed approach, which uses a combination of Remote Sensing (RS) and Geographical Information System (GIS) techniques, is an effective tool that enhances land-use monitoring, planning, and management of urbanized watersheds.
Histamine Formation and Its Control in Cheese: A Review
K Ekici,H. Coskun,T. Sienkiewicz
Journal of Food Technology , 2013,
Abstract: Histamine is one of the biogenic amine formed in the biological systems. Histamine is formed in fishes such as tuna and in the ripened cheeses. Fresh milk contains histamine in a low amount (<0.3) while cheeses may have the amount as high as 2500 ppm. Histamine content of the cheeses is affected by many factors. Ingestion of 70-1000 mg of histamine in a single meal is necessary to elicit any symptoms of toxicity. Histamine poisoning shows symptoms of rash, urticario, edema, and localized inflammation affect the cutareous system; nausea, vomiting, diarrhea, and abdominal cramps in gastrointestinal track. Hypotension, headache, palpitations, tingling, flushing and burning sensations in the mouth are the other symptoms. Different biogenic amines are predominant in different kind of cheeses. HPLC, gas-liquid chromatography and TLC are used to determine bigenic amines. Many enzymatic methods including enzymelinked immunosorbent assay (ELISA) have been developed to detect histamine in blood and tissues.
Water Quality Determination of Kü ük ekmece Lake, Turkey by Using Multispectral Satellite Data
Erhan Alparslan,H. Gonca Coskun,Ugur Alganci
The Scientific World Journal , 2009, DOI: 10.1100/tsw.2009.135
On the Inverse Problem of Dupire’s Equation with Nonlocal Boundary and Integral Conditions  [PDF]
Coskun Guler, Volkan Oban
Journal of Mathematical Finance (JMF) , 2017, DOI: 10.4236/jmf.2017.74051
Abstract: In this study, Inverse Problem for Dupire’s Equation with nonlocal boundary and integral conditions is studied. Then, by means of the some transformation, this equation is converted to diffusion equation. The conditions for the existence and uniqueness of a classical solution of the problem under consideration are established and continuous dependence of (p, v) on the data is shown. It is emphasized that this problem is well-posed.
Brucellosis: Retrospective Investigation of 140 Patients
H. Cem Gul,Omer Coskun,Vedat Turhan,Bulent A. Besirbellioglu
TAF Preventive Medicine Bulletin , 2007,
Abstract: Brucellosis is an important preventable disease for our country. To investigate by sharing our experience, 140 patients between January 1997 and December 2006 are watched out retrospectively. 113 patients were men and 27 patients were women. The prevalence of age was 27 ± 3.6 (19-72). Osteoarticular system is the most affected system with the prevalence of 41% of patients. The mostly seen clinical symptoms are; night sweat (81%), fatigue (76%), osteoarticular ache (65%). Since 46 % of our cases are closely related to high risk occupations for Brucellosis like animal breeding and agriculture, and this datum supports the classical understanding of Brucellosis epidemiology. [TAF Prev Med Bull. 2007; 6(4): 249-252]
Protective effect of leukotriene receptor antagonist montelukast on smoking-induced lung injury in Wistar rats.
Y??ksel H,Ozbilgin K,Coskun S,Tuglu I
Acta Medica Okayama , 2003,
Abstract: Increased activation of alveolar macrophage, neutrophil and mast cell has been proven in cigarette smoking (CS)-related lung disorders (CSLD). An increased production of cysteinyl-leukotrienes (LTs), which are mediators secreted from the mentioned cells, in response to CS has been shown in humans. The protective effect of LT1 receptor-1 antagonist (LTR-1AT) on CSLD is, however, not known. In this study we aimed to determine whether there is any protective effect of a LTR-1AT, montelukast (MK), on CSLD in Wistar rats. Nine controls and twenty-three smoke-exposed rats were enrolled into this study. Controls were exposed to non-filtered air, and the smoke-exposed rats were exposed to CS for 6 h/day, 6 days/week for three weeks. The CS-exposed rats were also treated with 0.1 mg/kg/day of MK or saline. Morphometric criteria for lung injury were determined as the mean linear intercept of alveolar septa (Lm), the volume density of alveolar septa (Vvspt) and the density of the alveolar surface area per unit volume of lung parenchyma (Sva.pa). Lung mast cells (LMC), which are a major source of LTs, were also counted. Results showed that Lm of the control group was significantly lower and Vvspt, Sva.pa of the controls were significantly higher compared to those of the CS-exposed groups. Animals treated with MK had significant protection against CSLD. Lm was significantly higher and Vvspt, Sva.pa were lower in the saline group than in the MK-treated group. The number of LMC in the CS-exposed groups was also significantly higher than that in the control group. Based on these results, one can suggest that some part of the pathogenesis of CSLD may be related to an enhanced LTs synthesis and LTR-1AT. Therefore, montelukast may protect against active or passive smoking-induced lung injury and related disorders.
Non-invasive evaluation of the adaptations of cardiac function in the neonatal period: a comparison of healthy infants delivered by vaginal route and caesarean section.
Coskun S,Y??ksel H,Bilgi Y,Lacin S
Acta Medica Okayama , 2001,
Abstract: Postnatal adaptations of cardiac hemodynamics in infants born vaginally or by caesarean section may be different. These cardiac functions were evaluated by Doppler echocardiography to assess adaptation differences. Cardiac output, heart rate, stroke volume, mean arterial pressure, total systemic vascular resistance, ejection fraction, and ductus arteriosus diameter were determined and compared at 1, 24 and 72 h of life in 22 infants born vaginally (group 1) and 23 born by caesarean section (group 2). One hour after delivery, heart rate, mean blood pressure, and total systemic resistance were found to be higher in group 1 infants (P < 0.01, P < 0.05, P < 0.05 respectively). Stroke-volume measurements were significantly higher in group 2 (P < 0.05). The ejection fraction and cardiac output values were similar in both groups. At 24 and 72 h, no significant differences were observed in measurements of infants born vaginally or by caesarean section. We did not find a parameter negatively affecting healthy newborns in either mode of delivery. However, under pathological conditions affecting the cardiovascular system at 1 h of life, including perinatal infections and hypoxemia, a lower stroke volume, higher heart rate, higher mean blood pressure, and higher peripheral resistance may cause additional work load to the cardiovascular system in infants born vaginally.
The results of Erciyes University in the treatment of advanced stage colorectal cancer
?zlem ER,H. ?enol COSKUN,Mustafa ALTINBA?,Metin ?zkan
Erciyes Medical Journal , 2003,
Abstract: Purpose: Determination of efficacy of 5-fluorouracil containing chemotherapy regimens in advanced colorectal cancer.Patients and Method: In this study, 74 advanced colorectal cancer patients followed at Erciyes University Medical Faculty Medical Oncology clinic between January 1994 and December 2000, to whom curative surgery could not be performed and palliative chemotherapy was administered, were evaluated retrospectively.Results: Of 74 patients 38 were male, 36 female and median age was 55 years (range 25-77). Twenty-five patients were in locally advanced stage, 49 patients in metastatic stage. 5-fluorouracil (FU) and folinic acid (FU+FA) was administered to 42 patients, FU to 13 patients, irinotecan/FU+FA to 10 patients, and FUdoxorubicin- mitomycin C (FAM) to 9 patients. Complete remission was obtained in 12 patients (16.2%), partial remission in 25 patients (45.6%). Median overall survival was calculated as 9.50 ±3.38 months and progression free survival 7.00 ±2.58 months in all patients. There was no statistically significant difference between FU+FA, FU, FAM, irinotecan/FU+FA chemotherapy groups in terms of progression free and overall survival (p=0.19 and 0.17 respectively).Conclusion: 5-FU combination chemotherapy has an important role in the treatment of advanced colorectal cancer. In respect to effect on survival and quality of life, treatment should be started immediately in good performance patients if curative surgery is not possible.
Pb-graphene-Pb Josephson junctions: characterization in B field
I. V. Borzenets,U. C. Coskun,H. Mebrahtu,G. Finkelstein
Physics , 2011,
Abstract: We fabricate superconductor-graphene-superconductor Josephson junctions with superconducting regions made of lead (Pb). The critical current through grapehene may be modulated by external magnetic field; the resulting Fraunhofer interference pattern shows several periods of oscillations, indicating that the junction is uniform. Deviations from the perfect Fraunhofer pattern are observed, and their cause is explained by a simulation that takes into account the sample design.
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