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Search Results: 1 - 10 of 150033 matches for " Hüsnü Topal "
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CO2 Acts as a Signalling Molecule in Populations of the Fungal Pathogen Candida albicans
Rebecca A. Hall,Luisa De Sordi,Donna M. MacCallum,Hüsnü Topal,Rebecca Eaton,James W. Bloor,Gary K. Robinson,Lonny R. Levin,Jochen Buck,Yue Wang,Neil A. R. Gow,Clemens Steegborn,Fritz A. Mühlschlegel
PLOS Pathogens , 2010, DOI: 10.1371/journal.ppat.1001193
Abstract: When colonising host-niches or non-animated medical devices, individual cells of the fungal pathogen Candida albicans expand into significant biomasses. Here we show that within such biomasses, fungal metabolically generated CO2 acts as a communication molecule promoting the switch from yeast to filamentous growth essential for C. albicans pathology. We find that CO2-mediated intra-colony signalling involves the adenylyl cyclase protein (Cyr1p), a multi-sensor recently found to coordinate fungal responses to serum and bacterial peptidoglycan. We further identify Lys 1373 as essential for CO2/bicarbonate regulation of Cyr1p. Disruption of the CO2/bicarbonate receptor-site interferes selectively with C. albicans filamentation within fungal biomasses. Comparisons between the Drosophila melanogaster infection model and the mouse model of disseminated candidiasis, suggest that metabolic CO2 sensing may be important for initial colonisation and epithelial invasion. Our results reveal the existence of a gaseous Candida signalling pathway and its molecular mechanism and provide insights into an evolutionary conserved CO2-signalling system.
Clinical approach to adnexal masses in adolescence
Hüsnü
Turk Pediatri Ar?ivi , 2011,
Abstract: The adnexal masses in adolescents contain functional and physiologic cystic formations on one end of the spectrum, and serious malignant tumors on the other end. The primary approach should be expectant management for the cysts which are thought to be benign in this spectrum. The most common malignant tumors in this era are germ cell tumors. The principal clinical approach in these tumors is to preserve organs and fertility. In malignant tumors a staging procedure should also be added. On the contrary, in disseminated tumors the primary surgery is cytoreductive or debulking surgery including radical organ extirpations. Post operative therapy is generally cis platin-containing combination chemotherapy. When tailoring management strategies, the development and psychology of the adolescent girls should be greatly considered as well as preserving fertility to be the ultimate aim of the treatment. Taking the subsequent therapy into consideration, a multidisciplinary approach should be the basis of the management of the malignant tumors of the adenexa. (Turk Arch Ped 2011; 46 Suppl: 111-4)
On certain sequence spaces II
Hüsnü Kizmaz
International Journal of Mathematics and Mathematical Sciences , 1995, DOI: 10.1155/s0161171295000925
Abstract: In this paper we define the space co( ”)={x=(xk)/xk ¢ ’kk ¢ ’1 ¢ ’0(k ¢ ’ ¢ ),xo=0,xk ¢ ¢ } and compute its duals (Continuous dual, 2-dual and N-dual) The aim of this paper is to give same results about matrix mapping of co( ”) into other sequence spaces including the convergent sequences, null sequences and bounded sequences.
The Protoindustrialism of Ottoman Textile Manufacture by The Examples of Kayseri Court Records
Hüsnü Yücekaya
Journal of Gazi Academic View , 2009,
Abstract: Textile industry was the first sector which comes in mind in manufacturing before the nineteenth century. The manufacturing of Ottoman is one of the eristic subjects which it hasn’t had a clear decision. It is thought that the manufacturers of Ottoman can’t realize transformation against the change of time and events, but this opinion is only a widespread prejudgement this article, The signs of protoindustrialism are tried to be propounded with some proofs that are got from the Kayseri court records at least for Kayseri.
REFLECTIONS FROM BASIC TECHNOLOGICAL PARADIGMATIC SHIFTS TO SOCIAL SCIENCES - TEMEL TEKNOLOJIK PARADIGMAL KAYMALARDAN SOSYAL BILIMLERE YANSIMALAR
Hüsnü Erkan
Istanbul Journal of Sociological Studies , 2012,
Abstract: Unlike other species, man is able to consider the action of thought. Technology is created by the implementation of the human mind and thoughts on nature. The leaps that are seen at the interaction between the human mind and nature/the universe are the shifts of intellectual and technological paradigms. Primitive man first used her or his hand in interaction with the environment. With the informational conglomeration that was provided, she or he formed objects from nature and so after a while traditional technologies were created in this way. The informational capacity available about the observable process of nature came up with the Newton laws as the first scientific revolution. As science oriented to invisible nature, which is subatomic and macro cosmos, instead of the observable one, the paradigm of quantum arose as the second scientific revolution. Society as a whole, which is based on sophisticated and multi-directional human relations, separated into sub- systems of economic, technological, social, political and cultural systems and all of these systems also have the mechanism of system, structure and process. This systematization and structuring emerged by themselves as well as having been designed as a product of the human mind, within the social evolution. The connected and dynamic interaction be- tween the systems, structures and processes which constitute society as a whole, creates a network settlement. Thus, nowadays in the Information Society, instead of the static, point-linear cause and effect explanations of mechanical thought, the paradigm of network interaction of social sciences, which is consistent with quantum thought, takes a major role. The paradigm of an interacting network is analogous to the model of neural networks which explains the functioning of the brain. The quantum model of physics, the neural network model of biology and the social sciences’ integrated network interaction model of society as a whole, are the parallel reflections of the second scientific revolution, which are being shaped in different fields. Moreover, both biological interaction networks and social interaction networks are those systems which configure and renew themselves by themselves (autopoietik systems). zetDi er canl lardan farkl olarak insan dü ünme üzerine dü ünebilir. nsan akl ve dü ünce- sinin do aya uyarlanmas teknoloji olarak ekillenir. nsan akl ile do a/evren etkile iminde g rülen s ramalar, dü ünsel ve teknolojik paradigmal kaymalard r. lkel insan, do a ile etkile iminde nce el’ini kulland . Sa lad bilgi birikimi ile do adan
The Opinions Of Student-Teachers On The Science Teaching Based On Multiple Intelligence Theory
Hüsnüye DURMAZ
Journal of Turkish Science Education , 2005,
Abstract: The purpose of this study is to define the student-teachers’ multiple intelligence fields, their opinions about the applicability of the theory in science teaching, about the positive or negative aspects of the science teaching based on the theory, and finally, about the feasibility of the theory, which might be a part of student centered teaching approach during teaching.
TUGRA IN THE CLASSICAL TURKISH POETRY AND TUGRAIYYE AS AN EXAMPLE OF LITERARY GENRE / KL S K TüRK S R NDE TU RA VE B R EDEB TüR OLARAK TU RA YYE
Ahmet TOPAL (M.A.H.)
Turkish Studies , 2009,
Abstract: Being a branch of calligraphy, the imperialmonogram (tugra) is one of the subject matters of theclassical Turkish poetry with regard to its form and itsfunction within the Ottoman social life. The poemswritten only to describe and praise the monogram of astatesman should be called tugraiyye implying the nameof the genre. In this article, definition for the genre hasbeen made considering the examples of tugraiyye whichwe could find out. Also we have studied the form of amonogram and descriptions of monogram in poems.
Leaf Area Estimation Model for Some Local Cherry Genotypes in Turkey
Leyla Demirsoy,Hsn? Demirsoy
Pakistan Journal of Biological Sciences , 2003,
Abstract: A leaf area estimation model was produced for 6 cherry cultivars namely, Karakiraz, Türkoglu, Tabaniyarik, K roglu, Kargayüregi and Barama, grown in Turkey. Lamina width, length and leaf area were measured to develop the model. The developed leaf area estimation model in the present study is: LA=(6,84-2,36XL+0,14XL2-0,016XWXL2+0,84XWXL) (r2=0.9809). In addition to model producing procedure, the model was validated using the residual values between predicted and measured leaf areas from new leaf samples of different cherry orchards. r2 values for the relationships between actual and predicted leaf areas of the tried cherry cultivars were found to be 0.9757.
Characteristics of Some Local Sweet Cherry Cultivars from Homeland
Hsn? Demirsoy,Leyla Demirsoy
Journal of Agronomy , 2004,
Abstract: This study was carried out during 2001 in Amasya in Turkey. The objective of the study was to characterize 5 sweet cherry cultivars grown in Amasya. In the cultivars; flowering occurred between the third week and the last of March and ripening was between the third week of May and the second week of June. The cultivars have a merit as gene resource in spite of small fruit of them.
Bir Kültür Merkezi Ba n n Hikayesi
Hüseyin Hüsnü Tek???k
Türk Kütüphanecili?i , 1996,
Abstract:
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