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Search Results: 1 - 10 of 327767 matches for " Hélvecio Cardoso Póvoa "
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Main Microbial Genres and Its Profile of Resistance and Sensitivity to Antimicrobials Used in the Treatment of Oncological Patients with Febril Neutropenia  [PDF]
Hélvecio Cardoso Póvoa, Richard Raphael Borges Tavares Vieira, Elias Sobreira Sathler, Isabela Nardoni Bernardes, Rafael Batista Ferreira, Mário Henrique Couto Lima, Thiago Sande Miguel, Nayrton Kalys Cruz dos Anjos, Lamara Laguardia Valente Rocha, Daniel Almeida da Costa
Journal of Biosciences and Medicines (JBM) , 2018, DOI: 10.4236/jbm.2018.61005
Abstract: Objective: To determine the main microbial genotypes and their antimicrobial resistance and susceptibility profile commonly used in the treatment of oncologic patients with febrile neutropenia, carried out through the review of the clinical histories of the patients’ medical records at the Hospital do Cancer de Muriaé-Fundacao Cristiano Varella. Methods: Quantitative research, determined the susceptibility profile of microorganisms in patients with febrile neutropenia from April 2007 to April 2008 by reviewing clinical histories of patients’ medical records at the referred hospital. Results: Of the total of 8 patients evaluated with Gram-negative microorganisms, 50% of the patients were female and 50% were male. Of the 18 patients evaluated with Gram-positive microorganisms 66% were female and 34% male. Gram-positive bacteria are prevalent and cause around 60% of documented bacteremias, although Gram-negative bacteria are more common in febrile neutropenic patientes. Conclusion: Exaggerated use of antimicrobials in hospitalized patients leads to the suppression of drug-sensitive microorganisms from the intestinal flora and promotes the persistence and growth of resistant bacteria. The antibiotic should be used in a curative manner with other therapeutic measures with the determined bacterial infection.
O processo de polariza??o em ceramicas de PZT
Lente, M. H.;Póvoa, J. M.;Eiras, J. A.;
Ceramica , 2000, DOI: 10.1590/S0366-69132000000200003
Abstract: in this work, the process of reorientation of domains during the polarization was investigated in "pure" and nb2o5 or fe2o3 doped pzt ceramics through electrical current transient and ferroelectric hysteresis measurements. the experimental results enabled to identify the mechanisms responsible for the polarization and their contributions to the total polarization. the release of the polarization after removal of the dc electric field was calculated and compared with results of ageing in these ceramics. the process of domain reorientation showed to be highly influenced by the presence of impurities.
O processo de polariza o em ceramicas de PZT
Lente M. H.,Póvoa J. M.,Eiras J. A.
Ceramica , 2000,
Abstract: Neste trabalho o processo de reorienta o dos domínios durante a polariza o foi investigado em ceramicas de PZT "puras" e dopadas com Nb2O5 ou Fe2O3 a partir de medidas do transiente de corrente elétrica e histerese ferroelétrica. Os resultados experimentais possibilitaram identificar os mecanismos responsáveis para a polariza o e suas contribui es para a polariza o total. A relaxa o da polariza o após a remo o do campo elétrico c.c. foi calculada e comparada com os resultados de envelhecimento destas ceramicas. O processo de reorienta o dos domínios mostrou ser altamente influenciado pela presen a de impurezas.
Termoativa??o da transaminase glutamico oxaloacética
Póvoa Júnior, Hélion;Almeida, Paulo Cesar Carvalho de;Alves, Orlando O.;Marcondes, Neusa;
Memórias do Instituto Oswaldo Cruz , 1973, DOI: 10.1590/S0074-02761973000300005
Abstract: glutamic oxalacetic transaminase is thermoativated. its optimum of catalytical activity is at 60oc. at this temperature, colour is approximately three times more intense than at 37oc, temperature usually utilized for determination of enzyme activity. this phenomenon is observed in human blood serum and several rat tissues (liver, heart, striated muscle, spleen, lung, kidney and blood serum).
A imagem da imprensa sobre a emigra??o brasileira
Póvoa Neto, Helion;
Estudos Avan?ados , 2006, DOI: 10.1590/S0103-40142006000200003
Abstract: brasilian emigration means something new for a country historically formed as an immigrant destination. more than exclusively demographic, this transition represents a social and political fact, which is being progressively recognized. this contribution evaluates discourses present in the press as relevant sources of information for the social perception of this change. thus, it analyzes news and articles about brazilians abroad that were published from 2001 to 2005.
Calorias s o calorias?
Póvoa Luiz Cesar
Arquivos Brasileiros de Endocrinologia & Metabologia , 2004,
Aspectos do 7o Joint
Póvoa Rui
Revista da Associa??o Médica Brasileira , 2004,
C-reactive protein, an early marker of community-acquired sepsis resolution: a multi-center prospective observational study
Pedro Póvoa, Armando M Teixeira-Pinto, António H Carneiro, the Portuguese Community-Acquired Sepsis Study Group (SACiUCI)
Critical Care , 2011, DOI: 10.1186/cc10313
Abstract: During a 12-month period a multi-center, prospective, observational study was conducted, segregating adults with Community-Acquired Sepsis. Patients were followed-up during the first five ICU days, day of ICU discharge or death and hospital outcome. CRP-ratio was calculated in relation to Day 1 CRP concentration. Patients were classified according to the pattern of CRP-ratio response to antibiotics: fast response if Day 5 CRP-ratio was < 0.4, slow response if Day 5 CRP-ratio was between 0.4 and 0.8, and no response if Day 5 CRP-ratio was > 0.8. Comparison between survivors and non-survivors was performed.A total of 891 patients (age 60 ± 17 yrs, hospital mortality 38%) were studied. There were no significant differences between the CRP of survivors and non-survivors until Day 2 of antibiotic therapy. On the following three days, CRP of survivors was significantly lower (P < 0.001). After adjusting for the Simplified Acute Physiology Score II and severity of sepsis, the CRP course was significantly associated with mortality (ORCRP-ratio = 1.03, confidence interval 95%= (1.02, 1.04), P < 0.001). The hospital mortality of patients with fast response, slow response and no response patterns was 23%, 30% and 41%, respectively (P = 0.001). No responders had a significant increase on the odds of death (OR = 2.5, CI95% = (1.6, 4.0), P < 0.001) when compared with fast responders.Daily CRP measurements after antibiotic prescription were useful as early as Day 3 in identification of Community-Acquired Sepsis patients with poor outcome. The rate of CRP decline during the first five ICU days was markedly associated with prognosis. The identification of the pattern of CRP-ratio response was useful in the recognition of the individual clinical course.Sepsis is a complex clinical syndrome that complicates severe infection and is characterized by systemic inflammation and widespread organ dysfunction [1,2]. Traditional clinical signs of sepsis, such as fever, tachycardia, tachypnea a
Estudos farmacognósticos, fitoquímicos, atividade antiplasmódica e toxicidade em Artemia salina de extrato etanólico de folhas de Montrichardia linifera (Arruda) Schott, Araceae
Costa, Eliene S. S.;Dolabela, Maria Fani;Póvoa, Marinete M.;Oliveira, Davi J.;Müller, Adolfo H.;
Revista Brasileira de Farmacognosia , 2009, DOI: 10.1590/S0102-695X2009000600006
Abstract: the present paper describes results of a pharmacognostic, a preliminary phytochemical study, brine shrimp toxicity and antiplasmodic activity in a strain of plasmodium falciparum that is resistant to chloroquine (w2) using ethanolic extract obtained from powder of the leaves of montrichardia linifera (arruda) schott, araceae. to perform the pharmacognostic studies methodologies employed in the brazilian pharmacopoea were utilized. the methods described by mattos were utilized for phytochemical prospecting. in the antiplasmodic test the traditional microtest was employed, as well as in the test with brine shrimp. the results obtained in the pharmacognostic studies with the powder from m. linifera leaves showed that it was a moderate thick powder, with water and ash totals within acceptable limits, low density (0.324 and 0.339 g/ml), ph close to neutral (6.69 ± 0.02). preliminary phytochemical analysis showed the presence of alkaloids, flavonoids, tannins, triterpenes and esters. the ethanolic extract from m. linifera leaves presented moderate antiplasmodic activity and low brine shrimp toxicity. to summarize, the powder used in preparing the extract presented good quality in pharmacognostic terms.
Microsatellite data suggest significant population structure and differentiation within the malaria vector Anopheles darlingi in Central and South America
Lisa Mirabello, Joseph H Vineis, Stephen P Yanoviak, Vera M Scarpassa, Marinete M Póvoa, Norma Padilla, Nicole L Achee, Jan E Conn
BMC Ecology , 2008, DOI: 10.1186/1472-6785-8-3
Abstract: We found high levels of polymorphism for all of the Amazonian populations (mean RS = 7.62, mean HO = 0.742), and low levels for the Belize and Guatemalan populations (mean RS = 4.3, mean HO = 0.457). The Bayesian clustering analysis revealed five population clusters: northeastern Amazonian Brazil, southeastern and central Amazonian Brazil, western and central Amazonian Brazil, Peruvian Amazon, and the Central American populations. Within Central America there was low non-significant differentiation, except for between the populations separated by the Maya Mountains. Within Amazonia there was a moderate level of significant differentiation attributed to isolation by distance. Within Peru there was no significant population structure and low differentiation, and some evidence of a population expansion. The pairwise estimates of genetic differentiation between Central America and Amazonian populations were all very high and highly significant (FST = 0.1859 – 0.3901, P < 0.05). Both the DA and FST distance-based trees illustrated the main division to be between Central America and Amazonia.We detected a large amount of population structure in Amazonia, with three population clusters within Brazil and one including the Peru populations. The considerable differences in Ne among the populations may have contributed to the observed genetic differentiation. All of the data suggest that the primary division within A. darlingi corresponds to two white gene genotypes between Amazonia (genotype 1) and Central America, parts of Colombia and Venezuela (genotype 2), and are in agreement with previously published mitochondrial COI gene sequences interpreted as incipient species. Overall, it appears that two main factors have contributed to the genetic differentiation between the population clusters: physical distance between the populations and the differences in effective population sizes among the subpopulations.Anopheles (Nyssorhynchus) darlingi is the most efficient malaria vect
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