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Search Results: 1 - 10 of 150049 matches for " H Ton "
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The Assessment of Non-Linear Effects in Clinical Research  [PDF]
Ton J. Cleophas, Aeilko H. Zwinderman
Pharmacology & Pharmacy (PP) , 2012, DOI: 10.4236/pp.2012.32021
Abstract: Background: Novel models for the assessment of non-linear data are being developed for the benefit of making better predictions from the data. Objective: To review traditional and modern models. Results, and Conclusions: 1) Logit and probit transformations are often successfully used to mimic a linear model. Logistic regression, Cox regression, Poisson regression, and Markow modeling are examples of logit transformation; 2) Either the x- or y-axis or both of them can be logarithmically transformed. Also Box Cox transformation equations and ACE (alternating conditional expectations) or AVAS (additive and variance stabilization for regression) packages are simple empirical methods often successful for linearly remodeling of non-linear data; 3) Data that are sinusoidal, can, generally, be successfully modeled using polynomial regression or Fourier analysis; 4) For exponential patterns like plasma concentration time relationships exponential modeling with or without Laplace transformations is a possibility. Spline and Loess are computationally intensive modern methods, suitable for smoothing data patterns, if the data plot leaves you with no idea of the relationship between the y- and x-values. There are no statistical tests to assess the goodness of fit of these methods, but it is always better than that of traditional models.
Steroid induced ocular hypertension following pterygium surgery
BK Khatri,H Ton
Health Renaissance , 2012, DOI: 10.3126/hren.v10i1.6009
Abstract: Background: Steroid induced glaucoma is an important cause of ocular morbidity and blindness. Objective: To determine the incidence of steroid induced ocular hypertension following pterygium surgery. Methods: A total of 202 eyes of 202 patients with primary pterygium which received steroid eye drops after undergoing surgical excision were selected. Pre-operative and post-operative intra-ocular pressure (IOP) were measured and followed up after 2nd and 6th weeks following surgery. Results: Ocular hypertension developed in 47 (23.27 %) eyes. The IOP returned to normal after two weeks following discontinuation of topical steroid drops (dexamethasone) and initiation of anti-glaucoma medication (Timolol drops 0.5% BD). Conclusion: Nearly one fourth of the patients receiving topical steroid following pterygium surgery presented with ocular hypertension. Measurement of IOP as early as 2 weeks of initiation of steroid drops helps identify steroid induced ocular hypertension. DOI: http://dx.doi.org/10.3126/hren.v10i1.6009 HREN 2012; 10(1): 57-58
P. Luykx, 'Daar is nog po zie, nog kleur, nog warmte'. Katholieke bekeerlingen en moderniteit in Nederland, 1880-1960
Ton H.M. van Schaik
BMGN : Low Countries Historical Review , 2009,
Th. Marius van Leeuwen, Keith D. Stanglin, Marijke Tolsma (eds.), Arminius, Arminianism, and Europe. Jacobus Arminius (1559/60-1609)
Ton H.M. van Schaik
BMGN : Low Countries Historical Review , 2012,
Arie de Groot, De Dom van Utrecht in de zestiende eeuw. Inrichting, decoratie en gebruik van de katholieke kathedraal
Ton H.M. van Schaik
BMGN : Low Countries Historical Review , 2012,
Reasons of general practitioners for not prescribing lipid-lowering medication to patients with diabetes: a qualitative study
Elisabeth AB, Petra Denig, Ton van Vliet, Janny H Dekker
BMC Family Practice , 2009, DOI: 10.1186/1471-2296-10-24
Abstract: A qualitative study with semi-structured interviews using real cases was conducted to explore reasons for not prescribing lipid-lowering medication after a guideline was distributed that recommended the use of statins in most patients with type 2 diabetes. Seven interviews were conducted with general practitioners (GPs) in The Netherlands, and analysed using an analytic inductive approach.Reasons for not-prescribing could be divided into patient and physician-attributed factors. According to the GPs, some patients do not follow-up on agreed medication and others object to taking lipid-lowering medication, partly for legitimate reasons such as expected or perceived side effects. Furthermore, the GPs themselves perceived reservations for prescribing lipid-lowering medication in patients with short life expectancy, expected compliance problems or near goal lipid levels. GPs sometimes postponed the start of treatment because of other priorities. Finally, barriers were seen in the GPs' practice organisation, and at the primary-secondary care interface.Some of the barriers mentioned by GPs seem to be valid reasons, showing that guideline non-adherence can be quite rational. On the other hand, treatment quality could improve by addressing issues, such as lack of knowledge or motivation of both the patient and the GP. More structured management in general practice may also lead to better treatment.Statins can lower cardiovascular events in patients with diabetes mellitus by around 25%.[1] Treatment guidelines for general practitioners in The Netherlands have recommended prescribing lipid-lowering drugs to almost all patients with type 2 diabetes mellitus. Despite these recommendations, the number of patients being treated has remained rather low. Studies in Dutch general practice showed that many diabetes patients were not receiving statin treatment.[2,3] Low percentages of prescribing are also seen in other countries.[4,5]Not prescribing medication as recommended by guidel
Exact controllability for a semilinear wave equation with both interior and boundary controls
Bui An Ton
Abstract and Applied Analysis , 2005, DOI: 10.1155/aaa.2005.619
Abstract: The exact controllability of a semilinear wave equation in a bounded open domain of Rn, with controls on a part of the boundary and in the interior, is shown. Feedback laws are established.
An inverse problem for a nonlinear Schr?dinger equation
Bui An Ton
Abstract and Applied Analysis , 2002, DOI: 10.1155/s1085337502204091
Abstract: We study the dependence on the control q of the interval ofdefinition of the solution u of the Cauchy problem ιu′
Time-dependent Stokes equations with measure data
Bui An Ton
Abstract and Applied Analysis , 2003, DOI: 10.1155/s1085337503308012
Abstract: We establish the existence of a unique solution of an initial boundary valueproblem for the nonstationary Stokes equations in a bounded fixed cylindrical domain with measure data. Feedback laws yield the source and its intensity from the partial measurementsof the solution in a subdomain.
An inverse problem for evolution inclusions
Bui An Ton
Abstract and Applied Analysis , 2002, DOI: 10.1155/s1085337502000702
Abstract: An inverse problem, the determination of the shape and aconvective coefficient on a part of the boundary from partialmeasurements of the solution, is studied using 2-person optimalcontrol techniques.
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