oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Search Results: 1 - 10 of 23 matches for " Gumersindo; Caturla-Such "
All listed articles are free for downloading (OA Articles)
Page 1 /23
Display every page Item
Utilización de la ventilación no invasiva en la insuficiencia respiratoria aguda: Estudio multicéntrico en unidades de cuidados intensivos Use of non-invasive ventilation in acute respiratory failure: Multicenter study in intensive care units
Miguel Fernández-Vivas,Gumersindo González-Díaz,Juan Caturla-Such,Francisco José Delgado-Vílchez
Medicina Intensiva , 2009,
Abstract: Objetivo. Estudiar el uso de la ventilación no invasiva (VNI) en la insuficiencia respiratoria aguda, en las unidades de cuidados intensivos (UCI) de Espa a. Métodos. Se realizó una encuesta a 254 UCI. Al final de ésta se invitó a participar en un estudio multicéntrico retrospectivo, y proporcionar información detallada sobre pacientes ventilados. Resultados. Contestaron 123 UCI; 119 utilizaban la VNI, de manera muy variable. En la enfermedad pulmonar obstructiva crónica (EPOC), la VNI fue de primera elección en el 89% de las unidades; en el edema agudo de pulmón (EAP), el 79%; en la insuficiencia respiratoria tras la extubación, el 53%; en la neumonía, el 53%, y en el síndrome de distrés respiratorio agudo (SDRA), el 17%. Su utilización en la EPOC fue ocasional o nula en el 11% de las unidades, y en el EAP, en el 21%. 18 hospitales enviaron información de 432 pacientes ventilados, de los que 232 (54%) recibieron VNI como primera elección. La neumonía o el SDRA fueron factores independientes en relación con el fracaso de la VNI (odds ratio ajustada [ORa] = 5,71; intervalo de confianza [IC] del 95%, 1,83-17,8; p = 0,003). La admisión en una unidad que ventilara de forma no invasiva a más de 50 pacientes/a o (ORa = 0,22; IC del 95%, 0,07-0,63; p = 0,005) y una mayor razón PaO2/FIO2 tras una hora de ventilación (ORa = 0,98 por punto; IC del 95%, 0,97-0,99; p < 0,001) fueron factores protectores. Conclusiones. La VNI es ampliamente utilizada en las UCI de Espa a, pero es posible que siga estando infrautilizada en la EPOC y el EAP. El diagnóstico de neumonía o SDRA fue un factor independiente en relación con el fracaso. Ventilar a más de 50 pacientes/a o y una mayor PaO2/FIO2 tras una hora fueron factores protectores. Objectives. Study the use of non-invasive ventilation (NIV) in patients with acute respiratory failure in intensive care units (ICUs) in Spain. Methods. A questionnaire was sent to 254 ICUs, after which, they were invited to participate in a multicenter, retrospective study, providing detailed information on ventilated patients. Results. Answers were received from 123 hospitals. Of these, 119 used NIV, although its use varied greatly. NIV is the treatment of choice in 89% of the units for chronic obstructive pulmonary disease (COPD), in 79% for acute pulmonary edema (APE), in 53% for postextubation failure, in 53% for pneumonia 53%, and in 17% for acute respiratory distress syndrome (ARDS). It was used occasionally in COPD in 11% of the units, and in 21% of the units for APE. Eighteen hospitals provided additional information on 432 ventilated
Utilización de la ventilación no invasiva en la insuficiencia respiratoria aguda: Estudio multicéntrico en unidades de cuidados intensivos
Fernández-Vivas,Miguel; González-Díaz,Gumersindo; Caturla-Such,Juan; Delgado-Vílchez,Francisco José; Serrano-Simón,José Manuel; Carrillo-Alcaraz,Andrés; Vayá-Moscardó,José; Galcerá-Tomás,José; Jaime-Sánchez,Francisco ángel; Solera-Suárez,Manuel;
Medicina Intensiva , 2009,
Abstract: objectives. study the use of non-invasive ventilation (niv) in patients with acute respiratory failure in intensive care units (icus) in spain. methods. a questionnaire was sent to 254 icus, after which, they were invited to participate in a multicenter, retrospective study, providing detailed information on ventilated patients. results. answers were received from 123 hospitals. of these, 119 used niv, although its use varied greatly. niv is the treatment of choice in 89% of the units for chronic obstructive pulmonary disease (copd), in 79% for acute pulmonary edema (ape), in 53% for postextubation failure, in 53% for pneumonia 53%, and in 17% for acute respiratory distress syndrome (ards). it was used occasionally in copd in 11% of the units, and in 21% of the units for ape. eighteen hospitals provided additional information on 432 ventilated patients, 232 (54%) of whom received niv as first line therapy. presence of pneumonia or acute respiratory distress syndrome (ards) was an independent predictive factor of niv failure (ora = 5.71; ci 95%, 1.83-17.8; p = 0.003). admission in a unit with experience in niv in > 50 patients/year (ora = 0.22; ci 95%, 0.07-0.63; p = 0.005) and a higher pao2/fio2 ratio after one hour of ventilation (ora = 0.98 per point; ci 95%, 0.97-0.99; p < 0.001) were protector factors. conclusions. in spain, niv is widely used but it may continue to be underused in copd and ape. the diagnosis of pneumonia or ards was an independent predictive risk factor. admission in an icu with niv in more than 50 patients/year also have higher pao2/fio2 ratio after one hour of ventilation were predictive factors of success.
Resolution of the Generalized Eigenvalue Problem in the Neutron Diffusion Equation Discretized by the Finite Volume Method
álvaro Bernal,Rafael Miró,Damián Ginestar,Gumersindo Verdú
Abstract and Applied Analysis , 2014, DOI: 10.1155/2014/913043
Abstract: Numerical methods are usually required to solve the neutron diffusion equation applied to nuclear reactors due to its heterogeneous nature. The most popular numerical techniques are the Finite Difference Method (FDM), the Coarse Mesh Finite Difference Method (CFMD), the Nodal Expansion Method (NEM), and the Nodal Collocation Method (NCM), used virtually in all neutronic diffusion codes, which give accurate results in structured meshes. However, the application of these methods in unstructured meshes to deal with complex geometries is not straightforward and it may cause problems of stability and convergence of the solution. By contrast, the Finite Element Method (FEM) and the Finite Volume Method (FVM) are easily applied to unstructured meshes. On the one hand, the FEM can be accurate for smoothly varying functions. On the other hand, the FVM is typically used in the transport equations due to the conservation of the transported quantity within the volume. In this paper, the FVM algorithm implemented in the ARB Partial Differential Equations solver has been used to discretize the neutron diffusion equation to obtain the matrices of the generalized eigenvalue problem, which has been solved by means of the SLEPc library. 1. Introduction The neutron diffusion equation is used to calculate the neutron flux distribution, which is one of the most important variables in a Nuclear Power Reactor (NPR). This equation is a simplification of the neutron transport equation using Fick’s Law, as discussed by Stacey [1]. Nevertheless, the use of the neutron diffusion equation is justified by the lower computational time and relatively low heterogeneity of commercial NPR. In order to calculate the spatial distribution of the neutron flux, the steady state of the neutron diffusion equation is considered by transforming the neutron diffusion equation into a generalized eigenvalue problem, explained in Section 2.1. The greatest eigenvalue is the most important one and it has a special interest for nuclear reactors safety. As a result, most methods used to calculate only this eigenvalue and utilizing iterative methods to avoid solving the generalized eigenvalue problem. Nevertheless, the calculation of several eigenvalues and eigenvectors is important for different applications as the modal analysis of nuclear reactors and BWR instabilities analysis, as discussed elsewhere [2, 3]. However, the resolution of this generalized eigenvalue problem could be a difficult task due to the large and sparse nature of the matrices. In this paper, the SLEPc library solves this problem.
Los implantes MG-OSSEOUS: Estudio multicéntrico retrospectivo
Serrano Caturla,E.; Martín-Granizo López,R.;
Revista Espa?ola de Cirugía Oral y Maxilofacial , 2006, DOI: 10.4321/S1130-05582006000600003
Abstract: objective. we present some statistically contrasted results regarding the survival and incidences of mg-osseous implants and prosthetic components (mozo-grau, s.l., valladolid, spain), and we prove that they have the same efficacy when compared with other commercial implants. material and methodology. this is a retrospective multicentric study coordinated by a company called scientific management in o&ss (barcelona, spain). 1001 dental implants were placed in 247 patients and 328 prostheses were designed between 2004 and 2005, with a follow-up of two years. all implants were loaded with prostheses. we detail and analyze each implant, according to the diameter, length, position, surgical timing, loadings, design and types of prostheses and complementary surgical procedures, either synchronic or metachronic. results. after the statistical method was homogenized, we were able to report an overall implant survival rate of 97.8% with monitoring of two years. the failures depending on the peculiarities of each clinical case are provided. no prosthetic failures are reported. discussion. the criteria and indications applied by the professionals to the mg-osseous implants are standardized depending on the clinical case. our results are compared with the international scientific literature, past and present, with these procedures totally agreeing with those found in the history of implantology. finally, our survey is compared with those published by the branemark team. conclusion. the mixture between the quality of the mgosseous implants and the scientifically supported criteria regarding the implants, reveals an implant failure of 2.2% over two years, with a survival of 100% of both the replaced implants and the loaded prostheses.
Nefropatía por contraste en el síndrome coronario agudo Contrast induced nephropathy in acute coronary syndrome
Mariana Carnevalini,Mariano Giorgi,Silvina Waldman,Nicolás Caturla
Medicina (Buenos Aires) , 2011,
Abstract: La nefropatía inducida por contraste (NIC) es una de las causas más frecuentes de insuficiencia renal en pacientes internados. En el síndrome coronario agudo (SCA), la presencia de NIC aumenta la morbimortalidad. Las medidas de profilaxis y los factores de riesgo intervinientes de NIC en SCA no han sido determinados con exactitud. El objetivo de este estudio fue evaluar la incidencia de NIC y los factores asociados a su desarrollo en pacientes ingresados en unidad coronaria con requerimiento de cinecoronariografía (CCG). Se realizó un estudio de cohorte retrospectivo. Se incluyeron pacientes consecutivos cursando SCA estudiados con CCG dentro de las 72 horas de su admisión. Se definió NIC al aumento del 25% del valor de creatinina a las 48 h sobre el nivel basal de ingreso. El período de inclusión fue entre el 1° de enero de 2004 hasta el 30 de junio de 2010. Se analizaron 125 casos. La incidencia de NIC fue del 10.4% (n = 13). En el análisis multivariado, los factores asociados independientemente a su desarrollo fueron la edad [OR 1.05 (IC 95% 1.004 - 1.11) p = 0.034], la angioplastia a múltiple vaso [OR 2.2 (IC 95% 1.07 - 4.8), p = 0.03] y el volumen de contraste utilizado [OR 1.007 (IC 95% 1.001 - 1.01), p = 0.014]. Contrast induced nephropathy (CIN) is one of the most frequent causes of acute renal failure in hospitalized patients. It is associated with an increase in morbidity and mortality in patients hospitalized for acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI). Risk factors and prevention strategies are not well defined. The aim of this study was to assess the incidence and clinical risk factors associated to the development of contrast induced nephropathy in patients hospitalized for ACS. In a retrospective cohort we analyzed consecutive patients hospitalized for ACS undergoing urgent PCI within 72 hours from the admission. CIN was defined as a 25% increase of creatinine levels from baseline at 48 hours from the PCI. The inclusion period was from January 1°, 2004 to June 30, 2010. A total of 125 patients were analyzed, and CIN occurred in 13 (10.4%) patients. An independent association was found between age (OR 1.05; 95% CI 1.004 to 1.11; p = 0.034), multiple vessel angioplasty (OR 2.2; 95% IC 1.07 to 4.8; p = 0.03) and the volume of contrast infused (OR 1.007; 95% CI 1.001 to 1.01; p = 0.014) with the development of CIN.
Los implantes MG-OSSEOUS: Estudio multicéntrico retrospectivo MG-OSSEOUS implants: A multicentric retrospective study
E. Serrano Caturla,R. Martín-Granizo López
Revista Espa?ola de Cirugía Oral y Maxilofacial , 2006,
Abstract: Objetivo. Aportar unos datos estadísticamente fiables sobre la supervivencia e incidencias asociadas a los implantes y prótesis del modelo MG-OSSEOUS (Mozo-Grau, S.L., Valladolid, Espa a) y demostrar que su eficacia es comparable a todas las marcas comerciales. Material y método. Estudio multicéntrico retrospectivo coordinado por la empresa Scientific Management in O&SS (Barcelona, Espa a). Se colocaron 1001 implantes en 247 pacientes y se dise aron 328 prótesis, entre los a os 2004 y 2005, con un seguimiento de 2 a os. Todos los implantes cargados. Se analizan y pormenorizan todos los implantes, por diámetros, longitudes, posiciones, fases quirúrgicas, cargas, tipos y modelos de prótesis y técnicas complementarias aplicadas, tanto sincrónica como anacrónicamente. Resultados. Tras la homogeneización de las muestras, se objetiva una supervivencia del 97,8% a los 2 a os, detallando los fracasos según las características de cada caso clínico. No se reporta ningún fracaso de la prótesis. Discusión. Protocolizamos una serie de criterios e indicaciones a la hora de colocar los implantes MG-OSSEOUS según los casos clínicos. Comparamos nuestros resultados con la bibliografía, tanto pretérita como actual, coincidiendo con la manera de actuar a lo largo de la historia de la implantología. Finalmente, extrapolamos los resultados que consideramos comparables a los publicados por el grupo Branemark. Conclusión. La calidad del implante MG-OSSEOUS combinada con protocolos implantológicos científicamente contrastados, muestra un 2,2% de fracaso a los 2 a os de seguimiento, con un porcentaje de éxito del 100% tanto en la recolocación del implante como en la fase protésica. Objective. We present some statistically contrasted results regarding the survival and incidences of MG-OSSEOUS implants and prosthetic components (Mozo-Grau, S.L., Valladolid, Spain), and we prove that they have the same efficacy when compared with other commercial implants. Material and methodology. This is a retrospective multicentric study coordinated by a company called Scientific Management in O&SS (Barcelona, Spain). 1001 dental implants were placed in 247 patients and 328 prostheses were designed between 2004 and 2005, with a follow-up of two years. All implants were loaded with prostheses. We detail and analyze each implant, according to the diameter, length, position, surgical timing, loadings, design and types of prostheses and complementary surgical procedures, either synchronic or metachronic. Results. After the statistical method was homogenized, we were able to report an overall implant
Mechanical annealing of metallic electrodes at the atomic scale
C. Sabater,C. Untiedt,J. J. Palacios,M. J. Caturla
Physics , 2012, DOI: 10.1103/PhysRevLett.108.205502
Abstract: The process of creating an atomically defined and robust metallic tip is described and quantified using measurements of contact conductance between gold electrodes and numerical simulations. Our experiments show how the same conductance behavior can be obtained for hundreds of cycles of formation and rupture of the nanocontact by limiting the indentation depth between the two electrodes up to a conductance value of approximately $5G_{0}$ in the case of gold. This phenomenon is rationalized using molecular dynamics simulations together with density functional theory transport calculations which show how, after repeated indentations (mechanical annealing), the two metallic electrodes are shaped into tips of reproducible structure. These results provide a crucial insight into fundamental aspects relevant to nano-tribology or scanning probe microscopies.
Understanding the structure of the first atomic contact in Gold
C. Sabater,M. J. Caturla,J. J. Palacios,C. Untiedt
Physics , 2013, DOI: 10.1186/1556-276X-8-257
Abstract: We have studied experimentally the phenomena of jump-to-contact (JC) and jump-out-of-contact (JOC) in gold electrodes. JC can be observed at the first contact when the two metals approach each other while JOC occurs in the last contact before breaking. When the indentation depth between the electrodes is limited to a certain value of conductance, a highly reproducible behaviour in the evolution of the conductance can be obtained for hundreds of cycles of formation and rupture. Molecular dynamics simulations of this process show how the two metallic electrodes are shaped into tips of a well-defined crystallographic structure formed through a mechanical annealing mechanism. We report a detailed analysis of the atomic configurations obtained before contact and rupture of these stable structures and obtained their conductance using first-principlesquantum transport calculations. These results help us understand the values of conductance obtained experimentally in the JC and JOC phenomena and improve our understanding of atomic-sized contacts and the evolution of their structural characteristics.
Screening of white rot fungal species for their capacity to degrade lindane and other isomers of hexachlorocyclohexane (HCH)
Quintero,Juan C; Moreira,María T; Feijoo,Gumersindo; Lema,Juan M;
Ciencia e investigación agraria , 2008, DOI: 10.4067/S0718-16202008000200005
Abstract: white-rot fungi have demonstrated a high capacity to degrade organic pollutants, including the insecticide lindane (y-hch). the purpose of this study was to evalúate the degradative capacities of several white rot fungi species, bjerkandera adusta, irpex lacteus, lentinus tigrinus, phanerochaete chrysosporium, phanerochaete sórdida, phlebia radiata, pleurotus eryngii, poliporus cialatus, and stereum hirsutum. fungal tolerance to various concentrations of a-, (3-, y- and 8 isomers of hexachlorocyclohexane (hch) was studied in both liquid and soil media samples. 8- and y-hch isomers showed the highest inhibition of fungal growth of all hch isomers. p. chrysosporium and b. adusta exhibited a high tolerance to hch pollution. the 8- and y-hch isomers were degraded between 15.1 and 70.8% by six of the nine fungal species, b. adusta, p. ciliatus, l. tigrinu, s. hirsutum, p. eryngii, and i. lacteus; [3-hch was 56.6, 26.5 and 23.9% degraded by b. adusta, p. ciliatus and p. eryngii, respectively in non-sterile soil, all the hch isomers were degraded between 8.2 and 17.5% by b. adusta immobilized on corncobs or woodchips. in nonsterile soil, other soil microflora showed an antagonistic effect on white-rot fungi catalyzed degradation of hch isomers.
PRODUCCIóN DE ENZIMAS LIGNINOLíTICAS CON HONGOS BASIDIOMICETOS CULTIVADOS SOBRE MATERIALES LIGNOCELULóSICOS
QUINTERO D.,Juan C.; Gumersindo,FEIJOO C.; LEMA R.,Juan M.;
Vitae , 2006,
Abstract: white rot fungi produce a ligninolytic enzymatic complex with capacity to degrade a wide spectrum of toxic and recalcitrant substances as plaguicides, dyes, polyaromatic hydrocarbons, explosives, etc., which cause pollution in soils and water bodies. the grown-on soil fungi?s ligninolytic enzyme production and contaminant biodegradation are favorable when fungi are inoculated with a mixer of pieces of lignocellulosic material in soil. these materials provide carbon source to maintain growth and induce enzymatic complex. fungi bjerkandera adusta y phanerochaete chrysosporium were employed to evaluated pieces of wood, corn cob and compost in order to produce ligninolytic enzymes manganese peroxidase (mnp) and lignine peroxidase (lip). pieces of wood provide an adequate support for production of mnp until 5.0 u/g dry material with bj. adusta and 1.3 u/g dry material with p. chrysosporium. corn cobs provide the best lip activities. ligninolytic enzymes only were detected in soil, when fungus was inoculated attached in these ligninolytic materials. these materials are appropriate for ligninolytic enzymes production and to inoculate fungus on contaminated soils.
Page 1 /23
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.