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Search Results: 1 - 10 of 140599 matches for " Goutam K. Jana "
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Pharmacognostic and antihyperglycemic study of Coccinia indica
Manish Gunjan,Goutam K. Jana,A. K Jha,Umashanker Mishra
International Journal of Phytomedicine , 2011,
Abstract: A comprehensive herbal drug therapeutic regimen offers time tested safe and effective support to conventional therapy in the management of diabetes. This is combination with adequate dietary management and physical activity would provide an integrated approach to the management of this deadly disease, particularly Type 2 diabetes. Additionally, due to unlimited potential of herbal drugs for innovative bioactive molecules, all efforts should be made to adopt a package of best practices encompassing conservation, cultivation, quality control, standardization and research and development for medicinal plants and herbals. Chronic administration of kundru fruit extracts (200mg/kg)for 14 days reduces the blood glucose level of the diabetes induced animals as compared to diabetic control group. There was significant decrease in the blood glucose level in the 7th[p<0.01] and 14th [p<0.001] days of the diabetes induction, showing antidiabetic effect of the concern fruit. The effect was comparable to that of standard antidiabetic drug Glibenclamide. The hypoglycemic effect of orally administered extracts of leaves and roots of Coccinia indica has been reported earlier but none of the literatures or paper shows the antidiabetic activity of fruit of the above plant as in crude extract while the whole fruit extract shows significant anti diabetic activity. Keywords: Diabetes; Coccinia indica; Hypoglycemic activity; Chronicle administration; Indigenous herbs
Pharmacognostic and antidiabetic study of Clitoria ternatea
Manish Gunjan,Ravindran M,Sengamalam R,Goutam K Jana
International Journal of Phytomedicine , 2011,
Abstract: Aparajita means "The Undefeated". This plant is a trailing creeper with the usual Indigo Blue colour flowers and the rare white ones which is more of a pale cream with a hint of green at the edges. In Kerala it is called the Sankhu Pushpam or Conch Shell flower although it hardly resembles a Conch shell. It actually resembles a quaint Snapdragon flower with it's front open. Graphically it represents the cutout of an inverted womb. May be that explains their close affinity to Indian Midwives, particularly the White variety. Aparajita grows throughout India. It is a beautiful-looking plant, hence cultivated in gardens. It is a perennial twining herb having 7 leaflets, which are elliptic and obtuse. There are few varieties with white, violet and blue flowers. The pods are 5-7 cm long, flat with 6 to 10 seed, in each pod. The flowers resemble in shape to cows ear, hence the synonym- gokarnika. Chronic administration of plant extracts (100mg/kg) for 14 days reduces the blood glucose level of the diabetes induced animals as compared to diabetic control group. There was significant decrease in the blood glucose level in the 7th [p<0.01] and 14th [p<0.001] days of the diabetes induction, showing antidiabetic effect. The effect was comparable to that of standard antidiabetic drug Glibenclamide. The aim of this research is to explore the antidiabetic activity of this plant which will be helpful in the future investigations. Keywords:- Diabetes, hypoglycemic activity, chronicle administration, indigenous herbs
Production of J/Ψ-Particles at RHIC and LHC Energies: An Alternative “Psi”-Chology  [PDF]
P. Guptaroy, Goutam Sau, S. K. Biswas, S. Bhattacharyya
Open Journal of Microphysics (OJM) , 2012, DOI: 10.4236/ojm.2012.22003
Abstract: We attempt here to understand successfully some crucial aspects of J/Ψ-production in some high energy nuclear collisions in the light of a non-standard framework outlined in the text. It is found that the results arrived at with this main working approach here is fairly in good agreement with both the measured data and the results obtained on the basis of some other models of the ‘standard’ variety. Impact and implications of this comparative study have also been precisely highlighted in the end.
Hypoglycemic effect of Swietenia macrophylla seeds against type II diabetes
Maiti Anup,Dewanjee Saikat,Jana Goutam,Mandal Subhash
International Journal of Green Pharmacy , 2008,
Abstract: The antidiabetic effect of Swietenia macrophylla seeds was evaluated in Streptozotocin and Nicotinamide induced type II diabetic rats. Methanol extract of Swietenia macrophylla seeds was administered orally at doses of 150 and 300 mg/kg body weight for 12 consecutive days. Fasting blood sugar (FBG) was estimated on overnight fasted rats on day 1, 5 and 12 days. Lipid profiles, liver glycogen levels and changes in body weight were also measured. The extract was found more effective at the dose of 300 mg/kg body weight and it lowered FBG levels was statistically significant P < 0.01 (32.78%) in diabetic rats at day 12. Extract at the same dose also significantly reduced P < 0.01 the elevated level of serum total cholesterol (18.56%) and triglyceride (10.41%), and increased P < 0.01 (46.27%) the reduced liver glycogen level. Though statistically non-significant the extract at both the doses was found to improve the body weight of diabetic rats. The observation concludes that the methanol extract of seeds of Swietenia macrophylla has hypoglycemic as well as hypolipidemic effect.
ANTIPYRETIC POTENTIAL OF DIFFERENT EXTRACTS OF CASSIA FISTULA LINN (FABACEAE) BARK
Jana Goutam Kumar,Patel Naresh,Sahoo Prasenjit,Gupta Anshita
International Journal of Research in Ayurveda and Pharmacy , 2010,
Abstract: Ethnobotany is a multidisciplinary science defined as the interaction between plants and people. On the basis of ethnomedicinal use, antipyretic activity of petroleum ether, ethyl acetate, chloroform, methanol extract of Cassia fistula Linn (Fabaceae) bark has been investigated in albino rats. Normal body temperature is regulated by a centre in the hypothalamus that ensures a balance between heat loss and production. Fever occurs when there is a disturbance of this hypothalamic ‘thermostat’, which leads to the set-point of body temperature being raised. Once there has been a return to the normal set-point, temperature regulating mechanism (dilatation of superficial blood vessels, sweating etc.) operates to reduce temperature. The study was carried out by using dose of 300 mg/kg orally. Experimental results exhibited that petroleum ether, ethyl acetate, chloroform, methanol extract of Cassia fistula bark, possess a significant antipyretic effect. After inducing 15% w/v suspension of yeast (1ml /100gm Body weight), temperature of experimental animal was increased. Then different extracts of the drug was induced into albino rats, which shows significant results. It was observed that methanol extract at a dose of 300 mg / kg body weight showed maximum antipyretic activity amongst other extracts which is statistically significant as the value of p<0.05.
An Asymptotic Distribution Function of the Three-Dimensional Shifted van der Corput Sequence  [PDF]
Jana Fialová, Ladislav Mi?k, Oto Strauch
Applied Mathematics (AM) , 2014, DOI: 10.4236/am.2014.515227
Abstract:

In this paper, we apply the Weyl's limit relation to calculate the limit \"\" \"\"where γq (n) is the van der Corput sequence in base q, g (x, y, z), is the asymptotic distribution function of (γq (n), γq (n +1), γq (n + 2)), and F (x, y, z) = max (x, y, z), min (x, y, z), and xyz, respectively.

Performance Evaluation of search engines via user effort measures
Rajesh Kumar Goutam,Sanjay K. Dwivedi
International Journal of Computer Science Issues , 2012,
Abstract: Many metrics exist to perform the task of search engine evaluation that are either looking for the experts judgments or believe in searchers decisions about the relevancy of the web documents. However, search logs can provide us information about how real users search. This paper explains, our attempts to incorporate the users searching behavior in formulation of user efforts centric evaluation metric. We also incorporate two dimensional users traversing approach in the ERR metric. After the formulation of the evaluation metric, authors judge its goodness and found that presented metric fulfills all the requirements that are needed for a metric to be mathematically accurate. The findings obtained from experiments, present a complete description for search engine evaluation procedure.
Nutrient conditions and chironomid productivity in Kolkata, India: assessment for biomonitoring and ecological management
Soumi Nandi,Gautam Aditya,Goutam K. Saha
Journal of Limnology , 2012, DOI: 10.4081/jlimnol.2012.e34
Abstract: The chironomid diversity in the water bodies are useful indicators of the nutrient and environmental states. A spatial scale analysis on the relative abundance of the chironomid species in the context of selected nutrient indicators like organic carbon (C), potassium ions (K+), nitrate (NO3ˉ), and phosphate (PO42ˉ) of the water bodies was assessed to justify the use of chironomids in environmental biomonitoring. Analysis of a sample of 90 data from eight different ponds of Kolkata, India, revealed the presence of 11 chironomid species in different relative densities. The chironomid immature productivity was found to be positively correlated with C and PO42ˉ of the water bodies, while no definite significant correlation was observed for K+, NO3ˉ. Based on these nutrients and the productivity of chironomids the ponds could be distinguished from one another. The abundance of three species of chironomid midges, Chironomus striatipennis, Chironomus circumdatus and Kiefferulus calligaster were prominent in all the water bodies. Cluster analysis showed that these species were highly correlated in their abundance contrast to others. The correspondence analysis showed distribution of the chironomid species to differ against the variance of nutrients. The results are supportive of the use of chironomid larvae in biomonitoring and ecological restoration of urban water bodies, through monitoring the nutrient status and the chironomid species assemblage. In this instance the chironomid species C. striatipennis, C. circumdatus and K. calligaster can specifically act as indicator of the nutrient state of the ponds.
Predatory activity of Rhantus sikkimensis and larvae of Toxorhynchites splendens on mosquito larvae in Darjeeling, India
Gautam Aditya, Anirban Ash & Goutam K. Saha
Journal of Vector Borne Diseases , 2006,
Abstract: Background & objectives: Predation potential of the dytiscid beetle, Rhantus sikkimensis Regimbart1899 and the larvae of Toxorhynchites splendens Wiedemann 1819 occurring along with the larvalstages of the mosquitoes in the annual lentic water bodies of Darjeeling was evaluated using thelarvae of Culex quinquefasciatus Say 1823 as preys, in the laboratory under simulated naturalconditions.Methods: Field collected R. sikkimensis and larvae of Tx. splendens were offered IV instar larvae ofCx. quinquefasciatus to observe the rate of predation, at varying prey and predator densities. Basedon the data obtained on the predation for a period of three consecutive days, two indices of predation,predatory impact (PI) and clearance rate (CR) values were estimated, and compared between thepredator species.Results: The rate of predation of IV instar Cx. quinquefasciatus larvae by R. sikkimensis rangedbetween 21.56 and 86.89 larvae per day, depending on the prey and predator densities. The PI valueremained between 18.67 and 35.33 larvae/day depending on prey densities, while the CR rangedbetween 2.21 and 2.23 larvae litres/day/predator. Compared to these, the Tx. splendens larvaeconsumed the prey larvae at the rate of 0.67 to 34.22 larvae per day, depending on the prey andpredator densities. The PI value ranged between 7.67 and 11.33 larvae/day, and the CR value rangedbetween 1.41 and 1.76 larvae litres/day/predator. The rate of predation, CR values and PI values ofR. sikkimensis and Tx. splendens varied significantly.Interpretation & conclusion: Both the predators R. sikkimensis and larvae of Tx. splendens canconsume a good number of mosquito larvae, though the rate of consumption between the twopredators vary owing to the difference in the life history traits and features. It can be assumed thatthese predators play an important role in larval population regulation of mosquitoes and therebyimpart an effect on species composition and interactions in the aquatic insect communities ofDarjeeling Hills, India.
Paradigm Shifts and a Possible Resolution of the PAMELA-Paradox in Astroparticle Physics
Goutam Sau,S. K. Biswas,S. Bhattacharyya
Physics , 2009,
Abstract: Very recently, PAMELA Collaboration has formally reported two sets of data on positron and antiproton flux measurements done at very high energies and with unprecedented accuracy. The reports reveal a puzzle of great topical interest and importance : it is decisively found that there is a sharp smooth rise of the positron fraction, whereas for antiproton production no such rises occur; rather the fraction either flattens, or shows signs of falling off gradually with increasing energies. The present work is just an attempt to decipher the riddle with the help of a host of radically new ideas about the particle-structure, the multiparticle-production mechanisms and the concept of nucleon break-downs into the constituent partons. The application of these ideas found remarkable successes in the past; exactly similar or more striking are the findings by the present study.
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