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Search Results: 1 - 10 of 32373 matches for " Gomes James "
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Eficácia de sistemas de informa??o e percep??o de mudan?a organizacional: um estudo de caso
Andrade, Davi Gomes de;Falk, James Anthony;
Revista de Administra??o Contemporanea , 2001, DOI: 10.1590/S1415-65552001000300004
Abstract: this paper is based on a case study involving 64 users of a hospital information system implanted in a large hospital in the city of recife, brazil. it is originated from the idea that the introduction of an information system should be regarded as an organizational change process, since it has a great potential of interfering with various aspects of the organization. the proposed hypothesis is that an information system tends to be considered efficacious when it is perceived as an element that contributes to the fulfilling of institutional objectives. in this study, was observed a positive correlation of 0.5011 between the degree of effectiveness attributed to the information system and the level of improvement in the quality of patient care perceived from the point of view of a group of users that works more directly with the pacients at the administrative tasks. the results suggest that the relationship between the variables may occur according to the degree that the proposed objectives, those formally declared, are congruent with the organizational objectives, those effectively sought by the personnel within the organization, and denominated by perrow as operational objectives.
James Lewis Gorman ; André Luís Gomes
Signótica , 2011, DOI: 10.5216/sig.v23i1.16145
Abstract: Busca-se no presente estudo estabelecer diálogos entre as obras Angústia, de Graciliano Ramos, e Dialética do Esclarecimento, de Adorno e Horkheimer, apoiados numa forma o conceitual que interliga o discurso, a sociedade e o sujeito, todos inseridos em seu contexto histórico. Nesse diálogo – conceito t o caro a Bakhtin (1895-1975) – do autor com seus personagens, dos personagens entre si na trama e da própria obra com o seu tempo, objetivamos evidenciar a capacidade de Graciliano Ramos de fazer entranhar sua obra com o sentimento e os valores de seu tempo e, ao mesmo tempo, torná-la universal, dialogando com seus pósteros. This article seeks to establish dialogues between Angústia, by Graciliano Ramos, and Dialética do esclarecimento, by Adorno and Horkheimer, reasoned by a conceptual that joins the discourse, society and the subject, all placed in their historical context. In this dialogue – a concept by Bakhtin (1895-1975) – between the author with his characters, the characters with themselves in the plot among and the work with its historical context, we aimed to demonstrate the Graciliano Ramos‘ability to make his work with the feeling and the values of his time and at the same time, to make it universal and for posterity.
Production of Bioethanol at High Temperature from Tari  [PDF]
Ali Azam Talukder, Sirajul Islam Sujon, Muhammad Maqsud Hossain, Donald James Gomes, Mamoru Yamada
Advances in Microbiology (AiM) , 2015, DOI: 10.4236/aim.2015.55033
Abstract: Many microorganisms can tolerate high-temperature ranges from 37°C - 45°C are called thermotolerant microorganisms. Eighteen such isolates containing various microorganisms were collected from the natural fermented products of Bangladesh in summer for bioethanol production. Cultural, morphological, physiological, biochemical and genetical analysis were carried out under various physiological conditions. Among them, two thermotolerant strains Tari-6, isolated from the Tari (an overnight natural fermented palm juice at around 33°C - 40°C) and Pvt-1, isolated from the Pantavat (an overnight natural fermented rice soaked with tap water at around 35°C - 37°C), produced high amount of bioethanol, 7.5% (v/v) and 6.5% (v/v), respectively at 37°C. Furthermore, a partial 26S rDNA sequencing results confirmed that the Tari-6 and Pvt-1 encoded Pichia galeiformi and Pichia guilliermondii, respectively, and later one could grow well in media containing Xylose. Our results conclude that these two yeast strains are the potential candidates for bioethanol production.
Stability and Blowout Behavior of Jet Flames in Oblique Air Flows
Jonathan N. Gomes,James D. Kribs,Kevin M. Lyons
Journal of Combustion , 2012, DOI: 10.1155/2012/218916
Abstract: The stability limits of a jet flame can play an important role in the design of burners and combustors. This study details an experiment conducted to determine the liftoff and blowout velocities of oblique-angle methane jet flames under various air coflow velocities. A nozzle was mounted on a telescoping boom to allow for an adjustable burner angle relative to a vertical coflow. Twenty-four flow configurations were established using six burner nozzle angles and four coflow velocities. Measurements of the fuel supply velocity during liftoff and blowout were compared against two parameters: nozzle angle and coflow velocity. The resulting correlations indicated that flames at more oblique angles have a greater upper stability limit and were more resistant to changes in coflow velocity. This behavior occurs due to a lower effective coflow velocity at angles more oblique to the coflow direction. Additionally, stability limits were determined for flames in crossflow and mild counterflow configurations, and a relationship between the liftoff and blowout velocities was observed. For flames in crossflow and counterflow, the stability limits are higher. Further studies may include more angle and coflow combinations, as well as the effect of diluents or different fuel types. 1. Introduction A multitude of studies have been performed on lifted jet flames and their behavior in various air flow configurations. In such partially premixed flames, the characteristics of the surrounding air flow (velocity, temperature) can strongly impact the overall combustion process and the stability parameters. As fuel flows from a nozzle and mixes with the air, the fuel and oxidizer concentrations vary throughout space and time. The extent of mixing due to turbulence also changes depending on the surrounding flow. The perpetually varying concentrations help to determine the overall behavior of a flame: its shape, velocity, size, color, temperature, and composition. In parallel, the heat release serves to laminarize regions and serves to limit reducing mixing. In particular, two important behavioral parameters are liftoff and blowout velocity. Initially, a jet flame will remain attached to the nozzle at low fuel velocities. However, at a critical jet velocity, the flame will lift off from the nozzle and stabilize at a position downstream due to the inability of the flame to remain anchored on the burner [1]. While there is, in general, a regime where the flame can stabilize, increasing the jet velocity will ultimately lead to blowout, in which the flame is extinguished. This behavior
Kinetic study of batch and fed-batch enzymatic saccharification of pretreated substrate and subsequent fermentation to ethanol
Rishi Gupta, Sanjay Kumar, James Gomes, Ramesh Kuhad
Biotechnology for Biofuels , 2012, DOI: 10.1186/1754-6834-5-16
Abstract: The enzymatic hydrolysis was carried out at elevated solid loading up to 20% (w/v) and a comparison kinetics of batch and fed-batch enzymatic hydrolysis was carried out using kinetic regimes. Under batch mode, the actual sugar concentration values at 20% initial substrate consistency were found deviated from the predicted values and the maximum sugar concentration obtained was 80.78 g/L. Fed-batch strategy was implemented to enhance the final sugar concentration to 127 g/L. The batch and fed-batch enzymatic hydrolysates were fermented with Saccharomyces cerevisiae and ethanol production of 34.78 g/L and 52.83 g/L, respectively, were achieved. Furthermore, model simulations showed that higher insoluble solids in the feed resulted in both smaller reactor volume and shorter residence time.Fed-batch enzymatic hydrolysis is an efficient procedure for enhancing the sugar concentration in the hydrolysate. Restricting the process to suitable kinetic regimes could result in higher conversion rates.Production of cellulosic ethanol from lignocellulosic biomass represents a potential alternative to the petroleum fuel due to its renewable nature and sustainable availability. Currently, the major strategy used for cellulosic ethanol production includes three main steps i.e., biomass pretreatment, enzymatic hydrolysis and ethanol fermentation [1,2]. The enzymatic hydrolysis contributes significantly to the cost of cellulosic ethanol and from the process economics perspective, the improvement in the enzymatic hydrolysis step is a prerequisite [3,4]. The main obstacles for enzymatic hydrolysis are low rate of reaction, high cost of enzyme, low product concentration and lack of understanding of cellulase kinetics on lignocellulosic substrates [5,6]. One way to overcome this problem is to operate the enzymatic hydrolysis using high insoluble solid consistency [7-9]. However, the saccharification reaction at high insoluble solid consistency will have to encounter the problems of increa
NeuroDNet - an open source platform for constructing and analyzing neurodegenerative disease networks
Vasaikar Suhas V,Padhi Aditya K,Jayaram Bhyravabhotla,Gomes James
BMC Neuroscience , 2013, DOI: 10.1186/1471-2202-14-3
Abstract: Background Genetic networks control cellular functions. Aberrations in normal cellular function are caused by mutations in genes that disrupt the fine tuning of genetic networks and cause disease or disorder. However, the large number of signalling molecules, genes and proteins that constitute such networks, and the consequent complexity of interactions, has restrained progress in research elucidating disease mechanisms. Hence, carrying out a systematic analysis of how diseases alter the character of these networks is important. We illustrate this through our work on neurodegenerative disease networks. We created a database, NeuroDNet, which brings together relevant information about signalling molecules, genes and proteins, and their interactions, for constructing neurodegenerative disease networks. Description NeuroDNet is a database with interactive tools that enables the creation of interaction networks for twelve neurodegenerative diseases under one portal for interrogation and analyses. It is the first of its kind, which enables the construction and analysis of neurodegenerative diseases through protein interaction networks, regulatory networks and Boolean networks. The database has a three-tier architecture - foundation, function and interface. The foundation tier contains the human genome data with 23857 protein-coding genes linked to more than 300 genes reported in clinical studies of neurodegenerative diseases. The database architecture was designed to retrieve neurodegenerative disease information seamlessly through the interface tier using specific functional information. Features of this database enable users to extract, analyze and display information related to a disease in many different ways. Conclusions The application of NeuroDNet was illustrated using three case studies. Through these case studies, the construction and analyses of a PPI network for angiogenin protein in amyotrophic lateral sclerosis, a signal-gene-protein interaction network for presenilin protein in Alzheimer's disease and a Boolean network for a mammalian cell cycle was demonstrated. NeuroDNet is accessible at http://bioschool.iitd.ac.in/NeuroDNet/.
Resource Competition May Lead to Effective Treatment of Antibiotic Resistant Infections
Antonio L. C. Gomes, James E. Galagan, Daniel Segrè
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0080775
Abstract: Drug resistance is a common problem in the fight against infectious diseases. Recent studies have shown conditions (which we call antiR) that select against resistant strains. However, no specific drug administration strategies based on this property exist yet. Here, we mathematically compare growth of resistant versus sensitive strains under different treatments (no drugs, antibiotic, and antiR), and show how a precisely timed combination of treatments may help defeat resistant strains. Our analysis is based on a previously developed model of infection and immunity in which a costly plasmid confers antibiotic resistance. As expected, antibiotic treatment increases the frequency of the resistant strain, while the plasmid cost causes a reduction of resistance in the absence of antibiotic selection. Our analysis suggests that this reduction occurs under competition for limited resources. Based on this model, we estimate treatment schedules that would lead to a complete elimination of both sensitive and resistant strains. In particular, we derive an analytical expression for the rate of resistance loss, and hence for the time necessary to turn a resistant infection into sensitive (tclear). This time depends on the experimentally measurable rates of pathogen division, growth and plasmid loss. Finally, we estimated tclear for a specific case, using available empirical data, and found that resistance may be lost up to 15 times faster under antiR treatment when compared to a no treatment regime. This strategy may be particularly suitable to treat chronic infection. Finally, our analysis suggests that accounting explicitly for a resistance-decaying rate may drastically change predicted outcomes in host-population models.
Temporal Trend of Carpal Tunnel Release Surgery: A Population-Based Time Series Analysis
Naif Fnais, Tara Gomes, James Mahoney, Sami Alissa, Muhammad Mamdani
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0097499
Abstract: Background Carpal tunnel release (CTR) is among the most common hand surgeries, although little is known about its pattern. In this study, we aimed to investigate temporal trends, age and gender variation and current practice patterns in CTR surgeries. Methods We conducted a population-based time series analysis among over 13 million residents of Ontario, who underwent operative management for carpal tunnel syndrome (CTS) from April 1, 1992 to March 31, 2010 using administrative claims data. Results The primary analysis revealed a fairly stable procedure rate of approximately 10 patients per 10,000 population per year receiving CTRs without any significant, consistent temporal trend (p = 0.94). Secondary analyses revealed different trends in procedure rates according to age. The annual procedure rate among those age >75 years increased from 22 per 10,000 population at the beginning of the study period to over 26 patients per 10,000 population (p<0.01) by the end of the study period. CTR surgical procedures were approximately two-fold more common among females relative to males (64.9% vs. 35.1 respectively; p<0.01). Lastly, CTR procedures are increasingly being conducted in the outpatient setting while procedures in the inpatient setting have been declining steadily – the proportion of procedures performed in the outpatient setting increased from 13% to over 30% by 2010 (p<0.01). Conclusion Overall, CTR surgical-procedures are conducted at a rate of approximately 10 patients per 10,000 population annually with significant variation with respect to age and gender. CTR surgical procedures in ambulatory-care facilities may soon outpace procedure rates in the in-hospital setting.
Family, Poverty and Inequalities in Latin America and the Caribbean  [PDF]
Cristina Gomes
Sociology Mind (SM) , 2013, DOI: 10.4236/sm.2013.31005

This article adopts the concept of development as freedom and the relationship between income and capabilities to analyze and compare macroeconomic, demographic and poverty trends and inequalities in Latin American and the Caribbean countries, and the responses from governments to promote the inclusion of the poorest and marginalized population groups in development and policies. Differences in population structures indicate that poverty and gender, generational and race inequalities fragment societies. Policies oriented to reduce poverty have been implemented with a set of combined programs such as cash transfers articulated with actions in nutrition, health, education, day-care programs for poor children, civil registration and other programs to promote poverty reduction and the conciliation of domestic and work life for poor women and social protection. Some good practices are discussed, particularly in Brazil and Mexico. During the last 15 years, the Conditioned Cash Transfers programs raised public support and political consensus, guaranteeing continuity in their implementation, development and integration with other social protection programs. Currently there are 18 countries implementing such programs, covering approximately 25 million households and over 133 million people, representing 19% of the Latin American and Caribbean. Policies to reduce poverty, in combination with income distribution and social protection in nutrition, health, education, civil registration and day-care for children, have contributed to human development, and also promoted internal market of consumers, even in rural areas, mobilizing local economies and promoting the return of investments to development. Despite the economic crisis in 2008-2009, Latin America had a relatively good performance in the world economy, demonstrating that social and economic

Family and women decide child nutrition—The role of human development, capabilities and lifestyles  [PDF]
Cristina Gomes
Health (Health) , 2013, DOI: 10.4236/health.2013.57153

In this article, capacities and freedom approach, as well as lifestyles are explored taking into account child nutrition, and other relevant dimensions of human life more than just economic and other elementary resources, and also social, cultural, psychological, values and freedom dimensions. Nourishment, health and survival are considered some of the elementary capabilities, and the concept of malnutrition, including under and over-nutrition, is discussed, based upon the comparison of data on food production and distribution from the macro level context, as well as from the family and individual levels included anthropometrical measurements. The advantages and limits of different kinds of measurements are discussed, suggesting more complex approaches, based also upon family and gender equality. The double burden of malnutrition, under and over-nourishment of children is highlighted as a public health issue to be resolved by adequate policies and considering the role of female empowerment, nutrition-knowledge and education as relevant keys to achieve equality in family food and resource distribution, healthy lifestyles and human development.

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