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Search Results: 1 - 10 of 256 matches for " Gokhan Atis "
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The Use of PSA Doubling Time to Predict Prognosis and the Use of PSA Response to Assess the Success for Prostate Cancer Patients Undergoing Docetaxel Chemotherapy  [PDF]
Sarp K. Keskin, Asif Yildirim, Cengiz Canakci, Ismail Ulus, Ramazan Gokhan Atis, Turhan Caskurlu
Journal of Cancer Therapy (JCT) , 2016, DOI: 10.4236/jct.2016.78062
Abstract: In the targeted therapy era, it is critical to know the certain points to start or discontinue chemotherapy for patients with castration resistant metastatic prostate cancer. The prognostic factors to determine this response are still not clear yet. We tried to find out if the PSA doubling time helps us to predict the patients who will benefit from docetaxel chemotherapy most, and also to question the value of the PSA response to chemotherapy. Retrospectively, 70 patients who had hormone refractory metastatic prostate cancer that were given at least 4 cycles of docetaxel chemotherapy between 2002 and 2015 were evaluated. After the onset of docetaxel, PSA response to therapy and overall survival rates were analyzed to figure out if these parameters were related to PSA doubling time. The only statistically significant prognostic parameter affecting overall survival was the best PSA response rate to docetaxel chemotherapy being over or under 50%. The most significant parameter that affects the PSA doubling time was the clinical stage at the time of diagnosis. PSA doubling time is not a useful predictive tool for predicting response to docetaxel. By means of overall survival, the clinical stage at the time of diagnosis was the best predictive tool for our cohort. The best PSA response rate to docetaxel chemotherapy was found to be a valuable parameter. The study being retrospective and the low number of patients included in this cohort can be the main weaknesses of this study. Further studies to determine which other factors can be useful are needed.
Intravesical Migration of an Intrauterine Device
Bayram Guner,OzgurArikan,Gokhan Atis,Lutfi Canat
Urology Journal , 2013,
Abstract: No Abstract
Reducing infectious complications after transrectal prostate needle biopsy using a disposable needle guide: is it possible?
Gurbuz, Cenk;Canat, Lutfi;Atis, Gokhan;Caskurlu, Turhan;
International braz j urol , 2011, DOI: 10.1590/S1677-55382011000100010
Abstract: purpose: to investigate whether the use of a disposable needle guide results in a decreased incidence of infectious complication after transrectal prostate needle biopsy (tpnb). materials and methods: fifty five patients who underwent 10-core tpnb were randomized into two groups. a pre-biopsy blood and urine examination was performed in both groups. group 1 (25 patients) underwent biopsy with disposable biopsy needle guide and group 2 (30 patients) underwent biopsy with reusable biopsy needle guide. all patients had a blood and negative urine culture before the procedure. the patients received ciprofloxacin 500 mg twice a day beginning the day before the biopsy and continued for 3 days after. serum c-reactive protein levels and urine and blood specimens were obtained 48h after the biopsy. primary endpoint of the study was to determine the effect of needle guide on the bacteriologic urinary tract infection (uti) rate and secondary end point was to determine symptomatic uti. results: the mean age of the patients was 63.46 (range 55 to 68) years. there were no significant differences regarding the prostate-specific antigen level, prostate size, existence of comorbidity in two groups before the procedure. bacteriologic and symptomatic uti was detected in 4% vs. 6.6% and 4% vs. 3.9% in group 1 and 2 relatively (p > 0.05). conclusion: the use of a disposable needle guide does not appear to minimize infection risk after tpnb. large scale and randomized studies are necessary to determine the effect of disposable needle guide on infection rate after tpnb.
Tissue Reaction of the Rat Urinary Bladder to Synthetic Mesh Materials
Gokhan Atis,Serdar Arisan,Aysim Ozagari,Turhan Caskurlu
The Scientific World Journal , 2009, DOI: 10.1100/tsw.2009.120
Abstract:
Primary Leiomyosarcoma of the Adrenal Gland: A Case Report with Immunohistochemical Study and Literature Review
Murat Tolga Gulpinar,Asif Yildirim,Berrin Gucluer,Ramazan Gokhan Atis,Cengiz Canakci,Cenk Gurbuz,Turhan Caskurlu
Case Reports in Urology , 2014, DOI: 10.1155/2014/489630
Abstract: Primary adrenal leiomyosarcoma is extremely rare tumor. We report a case with adrenal leiomyosarcoma. Our case was a 48-year-old man who presented with lower urinary tract symptoms. Ultrasonography and magnetic resonance imaging revealed approximately 9?cm solid mass originating from right adrenal gland. He underwent right adrenalectomy. Pathology of the specimen showed histologic and immunohistochemical features of adrenal leiomyosarcoma. 1. Introduction Primary leiomyosarcoma of the adrenal gland is a malignant tumor very rarely encountered in the literature and is without any specific findings by laboratory tests and radiologic imaging modalities. Herein, we present a rare case of primary leiomyosarcoma of the right adrenal gland in a 48-year-old male patient who presented with lower urinary tract symptoms. We aim to present a case with a definitive diagnosis of adrenal leiomyosarcoma, which was histopathologically established based on the microscopic examination and immunohistochemical staining of the specimen from the time of diagnosis to its treatment. A review of the recent literature is also presented. 2. Case A 48-year-old male patient consulted an outpatient urology clinic with complaints of frequent urination and awaking during night hours due to the need to urinate. During his physical examination, a mass was palpated on the upper right abdominal quadrant. Upon ultrasonography, a right adrenal mass measuring ?mm was detected, and the patient was hospitalized for further investigation and treatment. The mass was evaluated by the endocrinology department for identification. Upon abdominal magnetic resonance imaging (MRI), a ?mm hypervascular solid mass originating from the right adrenal gland and extending to the right hepatic lobe was observed, with intense contrast uptake on postcontrast images (Figures 1(a) and 1(b)). Figure 1: Magnetic resonance images of a 9?cm right adrenal leiomyosarcoma. T1-weighted images in coronal section (a) and transverse section show a homogenous solid mass in the right suprarenal area. (c) Macroscopic appearance of roundish, fibrous neoplasia. (d) Six months after right adrenalectomy, postoperative abdominal computerized tomography demonstrated no signs of local recurrence. The rectal examination findings and PSA values of the patient, whose father had been diagnosed with prostatic carcinoma, were within the normal limits. A routine laboratory examination and chest X-ray findings were unremarkable. To evaluate the endocrine activity of the mass, the 24-hour vanyl-mandelic acid, metanephrine, and normetanephrine
The Effects of Animation Technique on the 7th Grade Science and Technology Course  [PDF]
Gokhan Aksoy
Creative Education (CE) , 2012, DOI: 10.4236/ce.2012.33048
Abstract: The purpose of this study is to determine the effect of animation technique on academic achievement of students in the “Human and Environment” unit lectured as part of the Science and Technology course of the seventh grade in primary education. The sample of the study consists of 58 students attending to the 7th grade of Erzurum MEB Yildizkent IMKB primary school under two different classes during the 2011- 2012 academic year. While the lectures in the class designated as the animation group were given with animation technique, in the class designated as the control group Powerpoint presentations was utilized along with the traditional teaching methods. According to the findings, it was determined that animation technique is more effective than traditional teaching methods in terms of enhancing students’ achievement. It was also determined in the study that, the Powerpoint presentations used together with the traditional teaching methods provided to the control group significantly help the students to increase their academic achievement.
Magnetic Moment of Photon  [PDF]
Ziya Saglam, Gokhan Sahin
Journal of Modern Physics (JMP) , 2015, DOI: 10.4236/jmp.2015.67098
Abstract: We have calculated the intrinsic magnetic moment of a photon through the intrinsic magnetic moment of a gamma photon created as a result of the electron-positron annihilation with the angular frequency ω. We show that a photon propagating in z direction with an angular frequency ω carries a magnetic moment of μz = ±(ec/ω) along the propagation direction. Here, the (+) and (-) signs stand for the right hand and left circular helicity respectively. Because of these two symmetric values of the magnetic moment, we expect a splitting of the photon beam into two symmetric subbeams in a Stern-Gerlach experiment. The splitting is expected to be more prominent for low energy photons. We believe that the present result will be helpful for understanding the recent attempts on the Stern-Gerlach experiment with slow light and the behavior of the dark polaritons and also the atomic spinor polaritons.
A new automated method of e-learner's satisfaction measurement
Armands Strazds,Atis Kapenieks
International Journal of Emerging Technologies in Learning (iJET) , 2007,
Abstract: This paper presents a new method of measuring learner’s satisfaction while using electronic learning materials (e-courses, edutainment games, etc.) in virtual non-linear environments. Method is based on a relation of Discovering and Learning probability distribution curves obtained by collecting and evaluating the human-computer interaction data. While being near real-time, this measurement is considered highly unobtrusive and cost-effective because of its automated approach. The first working prototype EDUSA 1.0 was developed and successfully tested by the Distance Education Studies Centre of Riga Technical University.
A pilot study on self-perceived need for management training among medical students in Latvia
Juris Barzdins,Atis Barzdins
International Journal of Medical Education , 2013, DOI: 10.5116/ijme.5138.e068
Abstract: Objectives: To assess the self-perceived need and preferred format for educational intervention among Latvian medical students in fostering the increasing demanding of management-related competences for healthcare professionals. Methods: A cross sectional study design was used to assess student-perceived deficiencies and the need for knowledge and skills in 10 different domains of activity. All medical students from one of the two major Latvian universities were invited to participate in this survey. The knowledge gap between perceived deficiency and actual need for training in specific domains was calculated. Possible correlations between a total gap of knowledge and selected demographic parameters were identified. Results: The response rate to this web-based questionnaire was 101/458 (22. The most evident gaps were reported in the domains of Management of Legal Issues in Health Care (47, followed by the domains of National Healthcare System (37 and Management of Safety and Quality (37. The knowledge gap was wider among students with a higher degree of perceived competition their chosen speciality (R=0.25, p=0.011) and with a preference to work in private clinic (R=0.26, p=0.009), but it narrowed with advanced degree of studies (R= -0.27, p=0.006). Conclusions: This pilot study demonstrates that medical students recognise the necessity for additional training in management. It also highlights those domains of managerial skills and knowledge in which the students have observed the most notable existing deficiencies. These gaps and resultant issues should be addressed in the development studies programmes.
A Panoramic Look for School Sport in Turkey
Gokhan Caliskan
The Social Sciences , 2013,
Abstract: Sport between schools changed into a significant sport organization in last century. The general aim of supporting these organizations is either to provide well physical growing or their personality. In America, college sport started initially by rowing competition as unpretentious between students of Harvard and Yale Academy in 1852. Day by day, it changed into a significant sport organization. To carry out this sport organization systematically in 1920, a sport and activity programme, called NFHS in USA, which has 50 branch offices, serves 1,8500 school and 11 million student was used. The aim was to encourage students for sport by supporting school sport in USA. In Turkey, while generalizing the sport in base various projects were prepared and various organizations were arranged to direct the students to sport. Turkey School Sport Federation was founded by Centric Consultant Council of Youth and Sport General Management for the purpose of programming of all Ministry of Education Foundation’s sport activities in domestic and abroad, determining principals of sport activities, putting into force, on condition that educating a well generation and to increase the number of sportive to providing equipments of these activities and suchlike needs. In provinces, sport organizations between schools and in school were thought to be carried out by Ministry of Education, Physical Education, Intramural and Tracking General Management. It was provided that male-female 4 million students in categories of young, star performers and teenagers attended to intramural, local, group, semi-final and championship of Turkey first rank. The republic enacted various legislations, which encourage the sport and sportive. The republic tried to provide source and being a service area by creating various fund with GSGM law numbered 3289 but it could not be adequate. Having lots of branches in school for sport and equipments for this, to provide the expert trainer’s having duties in school can contribute to generalize the sport basically in the level of school except being a service area and transferring source.
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