oalib

OALib Journal期刊

ISSN: 2333-9721

费用:99美元

投稿

匹配条件: “Gohil Kashmira” ,找到相关结果约63条。
列表显示的所有文章,均可免费获取
第1页/共63条
每页显示
A review on Bacopa monniera: Current research and future prospects
Gohil Kashmira,Patel Jagruti
International Journal of Green Pharmacy , 2010,
Abstract: In recent times, the use of herbal products has increased tremendously in the western world as well as in developed countries. Lately, one of the outstandingly important medicinal plants, widely used therapeutically in the orient and becoming increasingly popular in the west is Bacopa monniera, a well-known nootropic. The present review summarizes our current knowledge of pharmacological actions, preclinical and clinical studies, major bioactives, reported mechanisms of actions, clinical efficacy, safety and the possibility of interactions of the herb with the conventional drugs. Simultaneously, research updates as well as avenues for further research are also mentioned concerning the plant.
Pharmacological review on Centella asiatica: A potential herbal cure-all
Gohil Kashmira,Patel Jagruti,Gajjar Anuradha
Indian Journal of Pharmaceutical Sciences , 2010,
Abstract: In recent times, focus on plant research has increased all over the world. Centella asiatica is an important medicinal herb that is widely used in the orient and is becoming popular in the West. Triterpenoid, saponins, the primary constituents of Centella asiatica are manly believed to be responsible for its wide therapeutic actions. Apart from wound healing, the herb is recommended for the treatment of various skin conditions such as leprosy, lupus, varicose ulcers, eczema, psoriasis, diarrhoea, fever, amenorrhea, diseases of the female genitourinary tract and also for relieving anxiety and improving cognition. The present review attempts to provide comprehensive information on pharmacology, mechanisms of action, various preclinical and clinical studies, safety precautions and current research prospects of the herb. At the same time, studies to evaluate the likelihood of interactions with drugs and herbs on simultaneous use, which is imperative for optimal and safe utilization of the herb, are discussed.
Rodent Antidepressant Models in Neuropsychopharmacology:A Laboratory Perspective
Gohil Kashmira J,Lawar Mayuri A
International Journal of Research in Pharmacy and Science , 2012,
Abstract: Transdermal drug delivery system was first introduced more than 20 years ago. Transdermal drug delivery system is a type of convenient drug delivery system where drug goes to the systemic circulation through the protective barrier i.e. Skin. Skin acts as a major target as well as a principal barrier for topical / transdermal drug delivery. Despite the many advantages of this system, the major obstacle is the low diffusion rate of drugs across the stratum corneum. One simple and convenient approach is application of drugs in formulation with elastic vesicles or skin enhancers. Vesicular system is one of the most controversial methods for transdermal delivery of active substances in that ethosome are the ethanolic phospholipids vesicles which are used mainly for transdermal delivery of drugs. Ethosomal drug delivery system is a new state of the art technique and easier to prepare in addition to safety and efficacy. Ethosomes have become an area of research interest, because of its enhanced skin permeation, improved drug delivery, increased drug entrapment efficiency etc. The purpose of writing this review on ethosomes drug delivery was to compile the focus on the various aspects of ethosomes including their mechanism of penetration, preparation, advantages, characterization, composition, application and marketed product of ethosomes. Ethosomal carrier opens new challenges and opportunities for the development of novel improved therapies
Warfarin-herb interactions: a review and study based on assessment of clinical case reports in literature
Jagruti A. Patel,Kashmira J. Gohil
Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas , 2008,
Abstract: El riesgo potencial de las interacciones entre hierbas y fármacos es de particular interés en la actualidad justamente por el incremento del uso de las hierbas. La mayor seguridad radica en el estrecho índice terapéutico de fármacos como la warfarina, un anticoagulante con un número máximo de reportes de interacciones. El objetivo del presente estudio fue conducir una revisión sistemática de la literatura para consolidar los reportes de casos clínicos de interacciones warfarina-hierbas para evaluar las fiabilidades de dichos reportes. Se revisó la literatura clínica publicada para consolidar y evaluar las interacciones entre varias hierbas y la warfarina, basado en los eventos adversos publicados, descripciones de los reportes de casos clínicos y las series de casos mediante las bases de datos electrónicas así como la selección de las referencias desde el a o 1971 hasta el 2007 y se alinearon sobre la probable causalidad mediante el algoritmo de Naranjo. Se obtuvieron 72 casos de reportes documentados de interacciones de warfarina con varias hierbas, 84.7% de los casos fueron evaluados como posibles interacciones (61/72) y 15.3% (11/72) como probables interacciones. El jugo de arándano fue el más comúnmente involucrado en las interacciones con warfarina con 34.7% de casos (25/72) de los cuales el 92% fueron interacciones posibles (23/25) y el 8% (2/25) fueron interacciones probables. De estos resultados se concluye que combinar anticoagulantes con hierbas parece ser una proposición arriesgada. El número de reportes de hierbas que actúan recíprocamente con warfarin continúa en aumento. Se aconseja específicamente a los pacientes que toman warfarina que eviten tomar medicinas herbarias o medir su INR a las dos semanas de arranque del fármaco, hacerlo de una forma más segura. De esta forma, se necesitan urgentemente estudios más sistemáticos sobre las interacciones de la warfarina y los productos herbales.
The Simulation and Analysis of the Closed Die Hot Forging Process by A Computer Simulation Method
Dipakkumar Gohil
Journal of Systemics, Cybernetics and Informatics , 2012,
Abstract: The objective of this research work is to study the variation of various parameters such as stress, strain, temperature, force, etc. during the closed die hot forging process. A computer simulation modeling approach has been adopted to transform the theoretical aspects in to a computer algorithm which would be used to simulate and analyze the closed die hot forging process. For the purpose of process study, the entire deformation process has been divided in to finite number of steps appropriately and then the output values have been computed at each deformation step. The results of simulation have been graphically represented and suitable corrective measures are also recommended, if the simulation results do not agree with the theoretical values. This computer simulation approach would significantly improve the productivity and reduce the energy consumption of the overall process for the components which are manufactured by the closed die forging process and contribute towards the efforts in reducing the global warming.
The Estimation of Forging Load for the Closed Die Forging Process by Computer Simulation
D. B. Gohil
Lecture Notes in Engineering and Computer Science , 2010,
Abstract:
ARM 7 Based Controller Area Network for Accident Avoidance in Automobiles
Kashyap Joshi,Vipul Gohil
Computer Science , 2014, DOI: 10.14445/22315381/IJETT-V9P212
Abstract: Based on requirements of modern vehicle, in- vehicle Controller Area Network (CAN) architecture has been implemented. In order to reduce point to point wiring harness in vehicle automation, CAN is suggested as a means for data communication within the vehicle environment. The benefits of CAN bus based network over traditional point to point schemes will offer increased flexibility and expandability for future technology insertions. This paper describes system which uses sensors to measure various parameters of the car like speed, distance from the other car, presence of alcohol in car and accidental change of lane and sends a warning signal to the driver if any of the parameter goes out of range to avoid accidents . In addition to this if accident occurs in any remote area then using bump sensor accident is detected and SMS is send immediately using GSM. A situation that provides a good example of how the system works is when a driver is about to change lanes, and there is a car in his blind spot. The sensors will detect that car and inform the driver before he starts turning, preventing him from potentially getting into a serious accident.
Review of the adaptation of skeletal muscle in intermittent claudication  [PDF]
Risha Gohil, Tristan Robert Alexander Lane, Patrick Coughlin
World Journal of Cardiovascular Diseases (WJCD) , 2013, DOI: 10.4236/wjcd.2013.34055
Abstract: Background: Despite awareness about the impact of intermittent claudication (IC) on mobility, balance and quality of life; the underlying pathophysiology and alterations in muscle architecture secondary to the disease are often overlooked. This review aimed to summarize the pathophysiological muscle changes present secondary to IC. Methods: The electronic databases, Medline, EMBASE, Cinahl and AMED, were searched for studies from 1967 to August 2011. Search terms included exercise, intermittent claudication and muscle. Studies about IC which were focused on muscle histology, muscle architecture, blood flow or changes with exercise were included. Results: Of 434 studies identified, 135 unique results were found. Only 78 of these were suitable from abstract review, of which 15 were unobtainable and a further nine were identified from hand-searching references. Studies in animal models demonstrated a predominance of type II muscle fibres and an improvement in animal exercise tolerance secondary to training. Exercise alone was never able to improve distances to that of healthy controls, however a lower limb fistula along with exercise did. Lower limb blood flow was demonstrated to be affected regionally, and most evident during exercise with a prolonged return to normal in patients with IC. At a cellular level, the myocytes metabolism increased in those with IC, but returned to normal post-revascularization. Conclusion: Treatment for claudicants includes either revascularization or exercise. Successful revascularization has demonstrated a return to normal muscle metabolism; the underlying physiological improvement secondary to exercise still requires clarification.


Population Status of Blister Beetle during Monsoon in Victoria Park Reserved Forest, Bhavnagar, Gujarat
B. M. Gohil,Devendra Solanki
Journal of Entomology and Zoology Studies , 2013,
Abstract: The Blister Beetles are widely distributed in the world. They have serious impacts, whether agronomic, veterinary or medical. The present investigation was carried out to know about population scenario of Blister Beetle in a reserve forest. Blister Beetle has special affinity to some plant species in particular season due to availability of food. In present study density of Blister Beetle was checked in form of density and its affinity towards plant Abutilon theophrastic was measured by RPE index which indicates the effect of plant presence on population of Blister Beetle.
On the equivalent width of the Fe K$α$ line produced by a dusty absorber in active galactic nuclei
Raj Gohil,David R. Ballantyne
Physics , 2015, DOI: 10.1093/mnras/stv326
Abstract: Obscured AGNs provide an opportunity to study the material surrounding the central engine. Geometric and physical constraints on the absorber can be deduced from the reprocessed AGN emission. In particular, the obscuring gas may reprocess the nuclear X-ray emission producing a narrow Fe K$\alpha$ line and a Compton reflection hump. In recent years, models of the X-ray reflection from an obscuring torus have been computed; however, although the reflecting gas may be dusty, the models do not yet take into account the effects of dust on the predicted spectrum. We study this problem by analyzing two sets of models, with and without the presence of dust, using the one dimensional photo-ionization code Cloudy. The calculations are performed for a range of column densities ($22 <{\rm log}[N_H(\rm cm^{-2})]< 24.5$ ) and hydrogen densities ( $6 <{\rm log}[n_H(\rm cm^{-3})]< 8$). The calculations show the presence of dust can enhance the Fe K$\alpha$ equivalent width (EW) in the reflected spectrum by factors up to $\approx$ 8 for Compton thick (CT) gas and a typical ISM grain size distribution. The enhancement in EW with respect to the reflection continuum is due to the reduction in the reflected continuum intensity caused by the anisotropic scattering behaviour of dust grains. This effect will be most relevant for reflection from distant, predominately neutral gas, and is a possible explanation for AGNs which show a strong Fe K$\alpha$ EW and a relatively weak reflection continuum. Our results show it is an important to take into account dust while modeling the X-ray reflection spectrum, and that inferring a CT column density from an observed Fe K$\alpha$ EW may not always be valid. Multi-dimensional models are needed to fully explore the magnitude of the effect.
第1页/共63条
每页显示


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.