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Search Results: 1 - 10 of 2126 matches for " Godoy MFG "
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Association of Godoy & Godoy contention with mechanism with apparatus-assisted exercises in patients with arm lymphedema after breast cancer
Godoy MFG, Guimaraes TD, Oliani AH, Godoy JMP
International Journal of General Medicine , 2011, DOI: http://dx.doi.org/10.2147/IJGM.S17139
Abstract: ssociation of Godoy & Godoy contention with mechanism with apparatus-assisted exercises in patients with arm lymphedema after breast cancer Original Research (2596) Total Article Views Authors: Godoy MFG, Guimaraes TD, Oliani AH, Godoy JMP Published Date May 2011 Volume 2011:4 Pages 373 - 376 DOI: http://dx.doi.org/10.2147/IJGM.S17139 Maria de Fátima Guerreiro Godoy1,4, Tania Dias Guimaraes2, Antonio Hélio Oliani1,3, José Maria Pereira de Godoy4 1CAPES (Coordination of Improvement of Higher Education Personal), S o José do Rio Preto, Brazil; 2Godoy Clinic, S o José do Rio Preto, Brazil; 3Gynecology and Obstetrics Department-FAMERP, S o José do Rio Preto, Brazil; 4Cardiology and Cardiovascular Surgery Department-FAMERP, S o José do Rio Preto, Brazil Aim: The aim of the current study was to evaluate the reduction in the volume of the upper limbs with lymphedema after exercises using the apparatus-assisted program associated with contention mechanism. Patients and method: Twenty-eight female patients were selected and referred for evaluation and treatment of lymphedema after breast cancer therapy. The ages of the women ranged from 42 to 72 years with a mean age of 57 years. Inclusion criteria were treatment of cancer associated to a difference of at least 200 mL between the edematous and the contralateral limbs. Patients with active infections, skin lesions, and active disease were not included in the study. Four series of exercises using devices based on pedals, pulleys, a horizontal reflexion bar, and an elevation bar were selected. The participants were advised about the form of exercise: 15 minutes for each device, low intensity (less than 10 movements per minute), in the seated position, and the use of contention. Water displacement volumetry was performed before and after the 60-minute exercise session. The paired t-test was utilized with an alpha error of 5% considered acceptable (P value < 0.05). Results: The mean difference between the volumetric measures before and after exercise was significant, with all the participants having reductions in the volume of the limbs using the four selected devices over time and at an intensity determined by this study. Conclusion: Association of a Godoy and Godoy contention during apparatus-assisted exercise reduced the edema in patients with lymphedema of the upper limbs.
Dynamic Evaluation of the Venous Pressure During Passive Plantar Flexion and Dorsiflexion Exercises with the RAGodoy Apparatus
Godoy JMP,Godoy MFG,Batigália F,Xavier MIG
Indian Journal of Physical Medicine and Rehabilitation , 2008,
Abstract: Objective: The objective of this case report was to dynamically evaluate pressure changes during passiveexercises using a device that performs plantar flexion and dorsiflexion.Design and setting: The medial vein of the left hallux was punctured using a 0.9 mm x 25 mm angiocatcatheter and this was connected to a DTX Plus TM sensor. With this portable apparatus, pressure variationsare measured at half-second intervals and the data stored in a numerical form. The RAGodoy apparatuswas used to perform passive exercises that stretched and bent the ankle joint.Six evaluations were made and the minimum and maximum pressures during each session were assessed.Main outcome measures and results: In all the sessions, variations in the pressures were obtained with aminimum pressure of 8 mmHg and a maximum of 77 mmHg.Conclusion: The device, named the RAGodoy , creates pressure variations in the venous system, whichassist blood flow in the lower limbs and thus it can be used to avoid venous stasis.
Analysis of parity between protein-based electrophoretic methods for the characterization of oral Candida species
Rosa EAR,Rosa RT,Pereira CV,Boriollo MFG
Memórias do Instituto Oswaldo Cruz , 2000,
Abstract: Electrophoretic studies of multilocus-enzymes (MLEE) and whole-cell protein (SDS-PAGE) were carried out in order to evaluate the parity between different methods for the characterization of five Candida species commonly isolated from oral cavity of humans by numerical taxonomy methods. The obtained data revealed that sodium dodecyl sulfate polyacrylamide gel electrophoresis is more efficient in grouping strains in their respective species while MLEE has much limited resolution in organizing all strains in their respective species-specific clusters. MLEE technique must be regarded for surveys in which just one species of Candida is involved.
Introducing Engineering Students to Historical/Cultural Perspectives through Story-Centered On-Line Learning  [PDF]
Luis A Godoy
Creative Education (CE) , 2011, DOI: 10.4236/ce.2011.22009
Abstract: Several authors argued that history of science should be an integral part of science education; however, there are many obstacles to carry out an implementation within this approach, including that lecturers normally lack a necessary historical background (a situation that is largely aggravated in engineering faculties), and the impossi- bility of including new courses or credits in an already tight curriculum. The development of on-line modules that engineering students can work outside their normal schedule of classes, introducing historical/cultural per- spectives, is presented in this paper. E-learning and knowledge management strategies are used in the context of science education at undergraduate and graduate levels. The approach is based on learning-by-doing in a virtual environment, and specifically presents story-centered activities, in which the student is faced with a problem and plays the role of an expert to provide a solution to the case. The specific case considered develops in the form of a controversy concerning the origin of the studies of column buckling. Two sets of information are available for navigation in the module: specific information that the student can explore (containing historical material di- rectly connected to the case provided), and more general information (providing the historical/cultural context to the problem). A first application has been made with civil engineering students, who had to write a two-page white paper as a consequence of their work on the problem. The interest generated in the participating students and the positive evaluation of their experience seems to indicate that this type of activity can serve to enhance traditional engineering lectures by incorporating a historical dimension. The present web-based approach could be extended to tackle similar conflicts in fields for which there is ample documentation available in the literature or in other historical episodes which may lead to rich discussions.
A Basis for Causal Scattering Waves, Relativistic Diffraction in Time Functions  [PDF]
Salvador Godoy, Karen Villa
Journal of Modern Physics (JMP) , 2016, DOI: 10.4236/jmp.2016.710107
Abstract: Relativistic diffraction in time wave functions can be used as a basis for causal scattering waves. We derive such exact wave function for a beam of Dirac and Klein-Gordon particles. The transient Dirac spinors are expressed in terms of integral defined functions which are the relativistic equivalent of the Fresnel integrals. When plotted versus time the exact relativistic densities show transient oscillations which resemble a diffraction pattern. The Dirac and Klein-Gordon time oscillations look different, hence relativistic diffraction in time depends strongly on the particle spin.
Limitations of drug registries to evaluate orphan medicinal products for the treatment of lysosomal storage disorders
Carla EM Hollak, Johannes MFG Aerts, Ségolène Aymé, Jeremy Manuel
Orphanet Journal of Rare Diseases , 2011, DOI: 10.1186/1750-1172-6-16
Abstract: The European Union enacted the Orphan Drug Regulation in 2000 ( (EC) No 141/2000 and (EC) No 847/2000) in order to improve the availability of innovative medicines for diseases affecting less than 5/10 000 people. Incentives to pharmaceutical companies include 10 years of market exclusivity, direct access to a Centralized Procedure for Marketing Authorization, scientific advice and fee reductions. Some orphan medicinal products (OMP's), especially those for extremely rare conditions, are approved by the European Medicines Agency (EMA) under "exceptional circumstances" due to the fact that it is unlikely that comprehensive data from clinical trials will become available [1]. Instead, pharmaceutical companies may be required to collect long-term data in a drug registry as part of their authorization. It is important to understand that registries can serve multiple purposes and therefore need different elements. With the increasing use of registries, requirements for each specific purpose are now better defined [2]. For example, registries that serve a public health purpose, such as those that are developed for population surveillance, do not need clinical data beyond diagnosis or follow-up data. On the other hand, registries that are being used to assess the effectiveness and safety of agents after authorization require more stringent elements. For these regulatory drug registries, completeness of case ascertainment, high quality clinical data, verification of data validity and follow-up is mandatory [2]. Existing drug registries for evaluation of the effectiveness of treatments for some orphan diseases have certain limitations in this respect. This has particularly become clear for the lysosomal storage disorders (LSD's). The LSD's comprise a group of very rare disorders which are all due to a deficiency of a lysosomal enzyme and display a variable range of phenotypes. Over the last two decades extremely costly treatments have been developed for these disorders. Ther
SELDI-TOF mass spectrometry of High-Density Lipoprotein
Johannes HM Levels, Boris Bleijlevens, Farhad Rezaee, Johannes MFG Aerts, Joost CM Meijers
Proteome Science , 2007, DOI: 10.1186/1477-5956-5-15
Abstract: To elucidate the protein composition of HDL, we employed SELDI-TOF mass spectrometry as a potential high-throughput proteomic candidate for protein profiling of HDL. HDL derived from normolipemic individuals was captured on PS20 protein-chips using covalently bound antibodies against apo A-I or A-II.After optimisation, on-chip capture of HDL particles directly from plasma or from pre-purified HDL resulted in comparable fingerprints confirming specific capture of HDL. Depending on the capture antibody some differences in the fingerprint were observed. The most detailed fingerprint was observed up to 50 kDa; approximately 95 peaks were detected in the 3–50 kDa molecular mass range. Between 50 and 160 kDa, 27 more peaks were detected.Based on these results, SELDI-TOF MS may be a suitable high-throughput candidate for HDL protein profiling and marker search. This approach may be used to i) investigate the underlying mechanisms that lead to increased atherothrombotic risk and ii) to investigate the atherothrombotic state of an individual.Vascular disease, and particularly atherothrombotic disease, is one of the major causes of death worldwide. Dyslipidemia, one of the primary risk factors of atherosclerosis, is characterized by elevated levels of atherogenic lipoproteins (chylomicron remnants, very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL)). In contrast, high-density lipoprotein (HDL) is inversely associated with the risk for cardiovascular disease [1].Intensive research over the past decade has elucidated the involvement of multiple pathways in atherogenesis, such as a long-term inflammatory and immune responses [2,3], hyper- and hypolipidemia, oxidation of LDL and HDL, coagulation and fibrinolysis [4-6]. Key markers of inflammation and the innate immune response include C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor-alpha, and several adhesion molecules [7]. Apart from decreases in the lipid content of HDL upon the inflamma
Phenotypic characterization of three clinical isolates of Burkholderia pseudomallei in Ceará, Brazil
Virginio, CG;Teixeira, MFS;Frota, CC;Café, VS;Rocha, MFG;Sidrim, JJC;
Memórias do Instituto Oswaldo Cruz , 2006, DOI: 10.1590/S0074-02762006000100018
Abstract: burkholderia pseudomallei, the causative agent of melioidosis was found in a small cluster of cases in teju?uoca, ceará, brazil. tests were carried out to determine its phenotypic characteristics: colony morphology on ashdown agar and macconkey agar, biochemical profile in conventional biochemical tests and api 20ne, arabinose assimilation and susceptibility testing by disk diffusion, comparing with data in the literature. this study confirms the presence of b. pseudomallei in brazil and describes its characteristics.
Onychomycosis in Ceará (Northeast Brazil): epidemiological and laboratory aspects
Brilhante, RSN;Cordeiro, RA;Medrano, DJA;Rocha, MFG;Monteiro, AJ;Cavalcante, CSP;Meireles, TEF;Sidrim, JJC;
Memórias do Instituto Oswaldo Cruz , 2005, DOI: 10.1590/S0074-02762005000200005
Abstract: knowledge of epidemiological and mycological characteristics of onychomycosis has been noted by many authors as being an important tool for control of these fungal infections. this study seeks to improve knowledge of onychomycosis epidemiology and mycological features. samples were taken from infected fingernails and toenails of 976 patients undergoing treatment at a respected dermatology center in ceará, fortaleza, ce, brazil. specimens from 512 patients (52%) were positive for onychomycosis. from the culture-positive samples, yeasts of the genus candida (c. albicans, c. tropicalis, c. krusei, c. parapsilosis) were dominant. the dermatophytes isolated (trichophyton rubrum, t. tonsurans, t. mentagrophytes var. mentagrophytes) were dominant in 46 patients (12.99%). the mould fusarium spp. was isolated from 29 patients (8.19%). yeast of the genus candida is the main causal factor in onychomycosis in our region. also, the study showed the importance of performing direct examination and culture in diagnosis of onychomycosis.
Analysis of parity between protein-based electrophoretic methods for the characterization of oral Candida species
Rosa, EAR;Rosa, RT;Pereira, CV;Boriollo, MFG;H?fling, JF;
Memórias do Instituto Oswaldo Cruz , 2000, DOI: 10.1590/S0074-02762000000600009
Abstract: electrophoretic studies of multilocus-enzymes (mlee) and whole-cell protein (sds-page) were carried out in order to evaluate the parity between different methods for the characterization of five candida species commonly isolated from oral cavity of humans by numerical taxonomy methods. the obtained data revealed that sodium dodecyl sulfate polyacrylamide gel electrophoresis is more efficient in grouping strains in their respective species while mlee has much limited resolution in organizing all strains in their respective species-specific clusters. mlee technique must be regarded for surveys in which just one species of candida is involved.
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