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Search Results: 1 - 10 of 491554 matches for " Gloria M Vásquez "
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Caracterización fenotípica y funcional de las subpoblaciones de monocitos en pacientes con lupus eritemaroso sistémico
Catalina Burbano-Arciniegas,Gloria M Vásquez,Mauricio Rojas-López
Actualidades Biológicas , 2012,
Abstract:
Prevalencia de falla ovárica y factores de riesgo en pacientes con Lupus Eritematoso Sistémico tratadas con ciclofosfamida intravenosa
Velásquez Méndez,Mónica Patricia; Ramírez Ruiz,Francisco Alejandro; Vásquez Duque,Gloria María; Ramírez Gómez,Luis Alberto;
Revista Colombiana de Reumatología , 2006,
Abstract: background: premature ovarian failure is a cyclophosphamide (cyc) treatment adverse effect. the report of prevalence is among 11% and 59%, the variability depend on the route and dosage of cyc. there are few studies about gonadal toxicity with nhi cyc treatment protocol. we decided to establish the prevalence and risk factors associated with premature ovarian failure in a group of latin-american lupus patients. methods: 56 sle patients under 40 years treated with intravenous cyc, with regular menstrual cycle at the beginning of the treatment, were compared with respect to the frequency of amenorrhea with 43 sle patients without treatment with cyc as a control group. after that, we studied in the cyc group the differences between those who made amenorrhea and those that continued with regular cycles. this is a cross sectional and descriptive study. the data were analyzed by chi-square, fisher’s exact test and mann-withney when it was necessary. p < 0.05 was considered significant. results: 16.1% of sle patients under intravenous cyc treatment get premature ovarian failure vs. 4.3% in the control group. with respect to cyc group, the mean age in the amenorrhea group was higher than the age in patients with regular menstrual cycles 35.2 vs. 26.7 years (p=0.03). we found than patients older than 28 years have a mayor risk for amenorrhea induced by intravenous cyc. the mean disease duration was higher in the amenorrhea group than in the regular menstrual cycle patients, p= 0.003 (10.2 vs. 4.4 years). no significant differences were observed in cumulative dosage, treatment duration or immunologic findings between groups. conclusion: the prevalence of ovarian failure in colombian women tends to appear at an early age and with a greater time of evolution of the disease in spite of inferior accumulated doses than those that are informed in the literature, suggesting a mayor susceptibility to toxic effect of cyc.
Prevalencia de falla ovárica y factores de riesgo en pacientes con Lupus Eritematoso Sistémico tratadas con ciclofosfamida intravenosa Prevalence of ovarian failure and risk factor in patients with systemic lupus erythematosus
Mónica Patricia Velásquez Méndez,Francisco Alejandro Ramírez Ruiz,Gloria María Vásquez Duque,Luis Alberto Ramírez Gómez
Revista Colombiana de Reumatología , 2006,
Abstract: Introducción: la falla ovárica prematura es una consecuencia del manejo a largo plazo con ciclofosfamida, su prevalencia en pacientes con LES ha sido informada entre el 11 y el 59%, dependiendo de la ruta y dosis de administración. Estudios sobre la toxicidad gonadal con el régimen propuesto por el NIH son escasos en la literatura, por lo cual se realizó este estudio para determinar la prevalencia y los factores de riesgo asociados al desarrollo de falla ovárica en una población latinoamericana. Métodos: se tomaron 56 pacientes con LES tratadas con bolos de CFM mensuales, menores de 40 a os y con menstruación normal al momento de iniciar la terapia y se compararon con respecto a la frecuencia de amenorrea con 43 pacientes con LES sin tratamiento con ciclofosfamida como grupo control. Posteriormente estudiamos en el grupo de CYC, las diferencias entre aquellas que hicieron amenorrea y las que continuaron con ciclos regulares. Este es un estudio descriptivo de corte transversal. Se aplicó chi-cuadrado, test exacto de Fisher y Mann-Withney según estuviese indicado. P menor de 0,05 se consideró significativo. Resultados: el 16,1% de los pacientes con CYC desarrollaron falla ovárica frente al 4,3% del grupo control. Con respecto al grupo que recibió CYC, se encontró un promedio de edad mayor en el grupo que desarrolló amenorrea que en aquellas con ciclos regulares, 35,2 frente a 26,7 a os (p= 0,003), determinándose como punto de corte de riesgo ser mayor de 28 a os al inicio de la CFM. La evolución de la enfermedad fue mayor en el grupo de amenorrea en comparación con las que continuaban con menstruación normal con una p= 0,003 (10,2 frente a 4,4 a os). No se encontró diferencia en la dosis acumulativa, duración de la terapia o perfil inmunológico de las pacientes. Conclusión: la prevalencia de falla ovárica en mujeres colombianas tiende a presentarse a una edad más temprana y con mayor tiempo de evolución de la enfermedad a pesar de dosis acumuladas inferiores a las informadas en la literatura planteando una mayor labilidad al efecto tóxico de la CFM. Background: premature ovarian failure is a cyclophosphamide (CYC) treatment adverse effect. The report of prevalence is among 11% and 59%, the variability depend on the route and dosage of CYC. There are few studies about gonadal toxicity with NHI CYC treatment protocol. We decided to establish the prevalence and risk factors associated with premature ovarian failure in a group of Latin-American lupus patients. Methods: 56 SLE patients under 40 years treated with intravenous CYC, with regular menstrual cycle at
Meningitis y artritis por Haemophilus influenzae en un adulto
Gloria Vásquez,Javier Molina
Iatreia , 1988,
Abstract: Tradicionalmente el Haemophilus influenzae ha sido considerado un germen causante de infecciones en ni os; en adultos se lo ha relacionado con Infecciones respiratorias, pero en los últimos tiempos se han descrito en ellos infecciones severas cuando hay algunos factores predisponentes. Se describe un paciente drogadicto de 30 a os con cuadro de meningitis y artritis y prueba de látex y cultivo de LCR positivos para HaemophiIus influenzae, quien recibió tratamiento con ampicilina, 2 gramos Intravenosos cada 4 horas y evolucionó a la mejoría sin secuelas. Se plantea la necesidad de tener en cuenta al Haemophilus influenzae como patógeno del adulto y más en aquellas personas con factores predisponentes. Haemophilus influenzae has traditionally been considered as an infectious agent that predominantly affects children; instead, in adults It has been Linked either to respiratory infections or to gevere infections occurring when predisposing factors are present. We describe a 30 year-old drug adict patient that presented with meningitis and arthritis; both latex test and cerebrospinal fluid culture were positive for Haemophilus influenzae. He was treated with ampicilin 2 gm, I. V. every four hours and improved without sequelae. This microorganism must be considered among those affecting adult patients specially when predisposing factors for infection are present.
Reticulohistiocitosis multicéntrica
Vargas,Francisco; Restrepo,Juan Pablo; Velásquez,Carlos Jaime; Velásquez,Mónica Patricia; Eraso,Ruth; González,Luis Alonso; Vásquez,Gloria; Uribe,Oscar; Ramírez,Luis Alberto; Correa,Luis Alfonso;
Revista Colombiana de Reumatología , 2007,
Abstract: multicentric reticulohistiocytosis (mrh) is a disease of unknown etiology that affects primarily women in the fourth decade of life. articular involvement is characterized by the presence of symmetric synovitis of the upper extremities, particularly of the hands, and compromise of the skin with lesions of different morphology, more commonly nodules and papules localized mainly on the face and upper extremities. there can also be involvement of internal organs such as lung, heart, gastrointestinal tract and salivary glands. this disease has been linked to malignant neoplasms of different organs like breast, ovary, uterine cervix and lymphomas, leading some authors to consider this disease a manifestation of a paraneoplastic syndrome. laboratory testing in these patients show abnormalities of the complete blood count, liver function tests as well as markers of autoimmunity. histological studies confirm the diagnosis by demonstrating giant multinucleated histiocytic cells (mononuclear histiocytes-diammeter of 50 to 100 μm) with an eosinophilic cytoplasm and fine granules that give the cells a ground glass appearance. multiple medications have been used to treat this disease including cyclophosphamide, azathioprine, methotrexate, chlorambucil and combined regimens. we document the case of a 51 year old caucasian female patient that was evaluated because of a 4 month history of subjective fever, weakness, fatigue, weight loss, inflammatory bilateral polyarthritis of the wrists, elbows and knees as well as the appearance of painful violaceous papules on the surface of the face, elbows, hands and flanks.
Complicaciones pulmonares de las miopatías inflamatorias idiopáticas: a propósito de un caso con miopatía diafragmática
Restrepo Escobar,Mauricio; González Naranjo,Luis Alonso; Pantoja Márquez,Adelis Enrique; Ramírez Gómez,Luis Alberto; Vásquez Duque,Gloria María;
Revista Colombiana de Reumatología , 2009,
Abstract: the idiopathic inflammatory myopathies are the largest group of acquired myopathies. on the basis of clinical, histopathological, immunological and demographic features, they can be differentiated into three distinct subsets: dermatomyositis, polymyositis and inclusion-body myositis. pulmonary involvement is increasingly recognized to be a serious complication and a common cause of morbidity and mortality in these diseases. there are three categories of pulmonary complications in inflammatory myositis: aspiration pneumonia, hypoventilation, and interstitial lung disease. respiratory failure caused by hypoventilation is considered to be an uncommon complication of inflammatory myositis which occurs in patients with severe generalized muscle weakness and inflammation of inspiratory and expiratory respiratory muscles. diaphragm weakness is frequent and probably overlooked in inflammatory myopathies. we report the case of a woman with inflammatory myopathy in whom the findings of the diaphragm muscles electromyography demonstrated inflammatory involvement of this muscle.
INTELIGENCIA EMOCIONAL E íNDICES DE BULLYING EN ESTUDIANTES DE PSICOLOGíA DE UNA UNIVERSIDAD PRIVADA DE BARRANQUILLA, COLOMBIA - EMOTIONAL INTELLIGENCE AND BULLYING RATE IN STUDENTS OF PSYCHOLOGY AT A PRIVATE UNIVERSITY IN BARRANQUILLA, COLOMBIA
FRANCISCO JAVIER VáSQUEZ DE LA HOZ,NAYIR MARíA áVILA LUGO,LUIS ORLANDO MáRQUEZ CHAPARRO,GLORIA MARTíNEZ GONZáLEZ
Revista Psicogente , 2010,
Abstract: Bullying as behavior that leads to complications in classroom coexistence would have deficiencies associated with emotional skills. Following the ideas of Mayer and Salovey (2007); Fernández-Berrocal and Extremera (2004), emotional intelligence and bullyingrate from a hundred volunteer students of psychology at a private university in Barranquilla, were compared. They were also applied the tests: TMMS-24 Fernandez- -Berrocal, Extremera and Ramos (2006) and the checklist my life at the university adapted from My life at school of Arora (1989) by Vasquez, ávila, Márquez, Martínez & Mercado (2008). Although they are not conclusive, the results suggest appropriate emotional intelligence and low bullying rate in most of participants; however we must not ignore the probability of manifestations of these behaviors in other members of the sample. For this reason, we suggest to adequate spaces for the strengthening of attention, clarity and emotional restoration skills to counteract manifestations of aggressive behaviour in the classroom.ResumenEl bullying, como conducta que genera complicaciones en la convivencia en el aula, tendría como factor asociado deficiencias en las habilidades emocionales. Siguiendo las ideas de Mayer y Salovey (2007); Fernández-Berrocal y Extremera (2004), se compararon la inteligencia emocional y el índice de bullying de 100 estudiantes voluntarios de Psicología de una universidad privada de Barranquilla, aplicándoseles el TMMS-24 de Fernández-Berrocal, Extremeray Ramos (2006) y la lista de chequeo Mi vida en la Universidad adaptado de Mi vida en la Escuela de Arora (1989) por Vásquez, ávila, Márquez, Martínez y Mercado (2008). Aun cuando no son concluyentes, los resultados si bien sugieren adecuada inteligencia emocional y bajoíndice de bullying en la mayoría de los participantes, no debe descartarse la probabilidad de aparición de estas conductas en los restantes miembros de la muestra, por lo cual se sugiere la creación de espacios propicios para el fortalecimiento de habilidades de atención, claridad y reparación emocional que contrarresten al aparición de conductas agresivas y maltratantes en las aulas.
Manifestaciones reumáticas de la infección por el virus de inmunodeficiencia humana (VIH)
Reino Buelvas,Alberto; Vásquez Duque,Gloria;
Iatreia , 2005,
Abstract: with the appearance of the hiv/aids complex several rheumatic manifestations have become evident. joint involvement includes arthralgia, hivassociated arthritis, reiter.s syndrome, psoriatic arthritis and undifferentiated spondyloarthropathy. a kind of myopathy induced by hiv has also been documented and it must be distinguished from zidovudine-induced, and toxoplasma-produced myopathies. diffuse infiltrative lymphocytosis syndrome (dils) is exclusive of patients positive for hiv; it resembles sj?gren.s syndrome but there are some clinical and immunological differences between them. the presence of autoimmune phenomena is frequent in hiv-infected patients; the most frequent of them is polyclonal hypergammaglobulinemia. different types of vasculitis have also been described in the hiv/aids complex.
Inmunología
Gloria María Vásquez Duque
Revista Colombiana de Reumatología , 2008,
Abstract:
Prevalencia de factores de riesgo cardiovascular clásicos en población adulta de Talca, Chile, 2005
Palomo G,Iván; Icaza N,Gloria; Mujica E,Verónica; Nú?ez F,Loreto; Leiva M,Elba; Vásquez R,Marcela; Alarcón L,Marcelo; Moyano D,Emilio;
Revista médica de Chile , 2007, DOI: 10.4067/S0034-98872007000700011
Abstract: background: cardiovascular disease (cvd) has several traditional risk factors (rf), and some of them are potentially modifiable. aim: to determine the prevalence of most common risk factors in adult population in talca in central chile. subjects and methods: we studied 1007 subjects aged 18 to 74 years (66% women), living in talca, selected by a probability sampling. they answered a questionnaire and anthropometry, blood pressure, lipid profile and blood glucose were measured. results: thirty seven percent of subjects smoked, 70.1% had a body mass index over 25 kg/m2 and 41% had an abnormally high circumference. high blood pressure was found in 37% (36% of these subjects were unaware of this condition), 44.5% had hypercholesterolemia, 21.5% had low hdl cholesterol, 40.1% had hypertriglyceridemia and 26.3% had high blood glucose levels. conclusions: there is a high prevalence of risk factors for cvd in adult population from talca. the prevalence of risk factors is higher than that reported by the 2003 national health survery
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