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Search Results: 1 - 10 of 626 matches for " Glen Weiser "
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A Review of Hypothesized Determinants Associated with Bighorn Sheep (Ovis canadensis) Die-Offs
David S. Miller,Eric Hoberg,Glen Weiser,Keith Aune,Mark Atkinson,Cleon Kimberling
Veterinary Medicine International , 2012, DOI: 10.1155/2012/796527
Abstract: Multiple determinants have been hypothesized to cause or favor disease outbreaks among free-ranging bighorn sheep (Ovis canadensis) populations. This paper considered direct and indirect causes of mortality, as well as potential interactions among proposed environmental, host, and agent determinants of disease. A clear, invariant relationship between a single agent and field outbreaks has not yet been documented, in part due to methodological limitations and practical challenges associated with developing rigorous study designs. Therefore, although there is a need to develop predictive models for outbreaks and validated mitigation strategies, uncertainty remains as to whether outbreaks are due to endemic or recently introduced agents. Consequently, absence of established and universal explanations for outbreaks contributes to conflict among wildlife and livestock stakeholders over land use and management practices. This example illustrates the challenge of developing comprehensive models for understanding and managing wildlife diseases in complex biological and sociological environments. 1. Introduction Effective management and conservation of wildlife populations can be undermined by multiple causes. These include decreased and altered habitat and other direct anthropogenic effects, climate change, competition and predation from nonnative wildlife and domestic species, demographic challenges associated with small populations, multiple, incompatible management objectives for sympatric species or their habitat, and exposure to native and exotic infectious agents [1–4]. The consequences and interactions of these variables are difficult to understand and predict, and may vary by circumstances. This uncertainty, particularly when it occurs in complex sociological environments where stakeholders have differing values and objectives, presents substantial challenges for decision makers. In such uncertain environments, the absence of data and differing values can result in polarized debate among stakeholders. It can also serve as an impediment to the acquisition of data that would contribute to effective management. Respiratory disease outbreaks in bighorn sheep (Ovis canadensis) illustrate the challenge of identifying and managing disease in valued wildlife populations, where stakeholder perceptions and values clash [5]. Bighorn sheep are highly valued for recreational, ecological, philosophical, spiritual, and other reasons [6]. Bighorns have experienced a population decline of two orders of magnitude subsequent to 19th century settlement of western North
“I’ve Got the Pilot”: An Interpretation of Flight, a Film by John Gatins, Writer, and Robert Zemeckis, Director  [PDF]
Judith Ferster, Paul Weiser
Advances in Literary Study (ALS) , 2014, DOI: 10.4236/als.2014.23013

Robert Zemeckis’s recent film Flight, about a talented but flawed commercial airline pilot (played by Denzel Washington) is discussed on both the realistic and allegorical levels, showing the relationship between the contemporary plot and the fifteenth-century morality play, The Summoning of Everyman. Evidence for and against the different kinds of interpretation is identified and discussed. The film forces the main character to make a series of progressively more difficult and significant ethical decisions about drugs, alcohol, friends (true and false), lovers, and personal atonement that challenge him. The audience must make an interpretive decision between the possible levels of meaning.

Top Physics at the LHC
Christian Weiser
Physics , 2005,
Abstract: Top quark physics will be a prominent topic in Standard Model physics at the LHC. The enormous amount of top quarks expected to be produced will allow to perform a wide range of precision measurements. An overview of the planned top physics programme of the ATLAS and CMS experiments at the LHC is given.
Networks Unplugged: Towards A Model of Compatibility Regulation Between Information Platforms
Phil Weiser
Computer Science , 2001,
Abstract: Networks Unplugged: Towards A Model of Compatibility Regulation Between Information Platforms This Article outlines a basic model for regulating interoperability between rival information platforms. In so doing, it insists that antitrust, intellectual property, and telecommunications regulation all must follow the same set of principles to facilitate competition between rival standards where possible, mandating or allowing cooperation only where necessary to facilitate competition within a standard when network-level competition is infeasible. To date, the antitrust regime best approximates the type of model I have in mind, but sound competition policy requires that telecommunications regulation and intellectual property law follow its basic principles as well.
Crises in Education: Online Learning as a Solution  [PDF]
Hershey H Friedman, Linda Weiser Friedman
Creative Education (CE) , 2011, DOI: 10.4236/ce.2011.23022
Abstract: There are three serious problems facing education today. These include working with draconian budgets that mean reduced spending for education, making education interesting and relevant for students, and raising standards. Several issues that the legislators are especially concerned about are the low retention rates at the college level, the high dropout rates in the high schools, and the long time it takes undergraduate students to graduate college. The authors show how online learning may be an important tool for solving these problems.
Shared Bacterial and Viral Respiratory Agents in Bighorn Sheep (Ovis canadensis), Domestic Sheep (Ovis aries), and Goats (Capra hircus) in Montana
David S. Miller,Glen C. Weiser,Keith Aune,Brent Roeder,Mark Atkinson,Neil Anderson,Thomas J. Roffe,Kim A. Keating,Phillip L. Chapman,Cleon Kimberling,Jack Rhyan,P. Ryan Clarke
Veterinary Medicine International , 2011, DOI: 10.4061/2011/162520
Abstract: Transmission of infectious agents from livestock reservoirs has been hypothesized to cause respiratory disease outbreaks in bighorn sheep (Ovis canadensis), and land management policies intended to limit this transmission have proven controversial. This cross-sectional study compares the infectious agents present in multiple populations of bighorn sheep near to and distant from their interface with domestic sheep (O. aries) and domestic goat (Capra hircus) and provides critical baseline information needed for interpretations of cross-species transmission risks. Bighorn sheep and livestock shared exposure to Pasteurellaceae, viral, and endoparasite agents. In contrast, although the impact is uncertain, Mycoplasma sp. was isolated from livestock but not bighorn sheep. These results may be the result of historic cross-species transmission of agents that has resulted in a mosaic of endemic and exotic agents. Future work using longitudinal and multiple population comparisons is needed to rigorously establish the risk of outbreaks from cross-species transmission of infectious agents. 1. Introduction Bighorn sheep (Ovis canadensis) experienced substantial decreases in population numbers and range in the 19th and the early 20th centuries, and subsequent recovery efforts have often been limited by large-scale die-offs [1–3]. These initial population declines were associated with settlement of western North America and were attributed to unregulated hunting, competition for forage with domestic sheep (O. aries) and other livestock, and disruption of historic bighorn sheep migration patterns due to development. Clinical disease was apparently unimportant or was underreported in these early declines, though die-offs of bighorn sheep associated with sheep scab (Psoroptes sp.) were reported following settlement [4, 5]. Bighorn sheep die-offs associated with pneumonia were reported in the 1920s and 1930s [6–10]. These early reports and subsequent work largely focused on lungworm (Protostrongylus sp.) as the primary infectious agent, although the involvement of Pasteurella sp., Corynebacterium pyogenes (currently Arcanobacterium pyogenes), and other host and environmental determinants were also noted as potential causes of respiratory disease. Subsequently, inconsistent association of lungworm with respiratory disease in bighorn sheep, as well as further evidence for Pasteurella sp. as the cause of pneumonia, led to a focus on pasteurellosis as a cause of respiratory disease outbreaks [11–14]. This research included evidence that Pasteurella sp. strains from clinically
Extrinsic electromagnetic fields, low frequency (phonon) vibrations, and control of cell function: a non-linear resonance system  [PDF]
Glen A. Gordon
Journal of Biomedical Science and Engineering (JBiSE) , 2008, DOI: 10.4236/jbise.2008.13025
Abstract: Chou and Chen’s report in the 1970s suggested conformational protein adaptation (CPA) might be influenced by low frequency phonons acting as “a possible information system”. This report proposes the universal force of electromagnetism initiates the phonon system they cited as it per-turbs paramagnetic/diamagnetic dampers within the protein matrix to produce a quantized low frequency phonon signal series. (http://www.phy.ilstu.edu/~ren/phononsims/page3.html) The signal series is iteratively processed by the protein beta sub-unit, the system, to posi-tion the alpha sub-unit, the outcome, a classic non-linear resonance system resulting in con-formational protein adaptation (CPA). CPA “priming” enables a secondary ATP/redox driven power system to complete cell activity. The evolutionary appearance of these two systems reflects their hierarchy: 1) a low energy phonon driven information control circuit governed by principles of physics that, along with proteins, may have preceded planet earth, and 2), an ATP/redox power completion circuit directed by principles of chemistry that evolved in living systems 1 billion or more years after earth formed.
Gauge Coupling Unification in Left-Right Symmetric Models
Manfred Lindner,Manfred Weiser
Physics , 1996, DOI: 10.1016/0370-2693(96)00775-7
Abstract: We explore possibilities of gauge coupling unification in left--right symmetric models with non--minimal particle content. In addition to unification we require the absence of anomalies and sufficient proton lifetime. Numerous previously unknown solutions are presented where unification occurs within the latest experimental errors. Solutions exist where the scale of left--right symmetry breaking can be as low as ${\cal O}(TeV)$ or the scale $M_R$ as high as the Planck scale.
The Relationship between Impaired Methylnicotinate Response and Oxidative Stress in Schizophrenia  [PDF]
Brian M. Ross, Iain Glen
Open Journal of Psychiatry (OJPsych) , 2014, DOI: 10.4236/ojpsych.2014.42018

MNA response applied methylnicotinate (MNA) results in an arachidonic acid and cyclooxygenase-dependent vasodilatatory response which is diminished in patients with schizophrenia. This observation has been suggested to form the basis of a diagnostic test for the illness although the potential utility of such a procedure is diminished since the underlying mechanism is unclear. In this study we sought to discover if reduced MNA response in schizophrenia is related to increased oxidative stress i.e. whether or not the two measures are negatively correlated with each other. MNA response was assessed visually in 17 patients with schizophrenia and 16 healthy controls and compared to the extent of oxidative stress in each participant assessed by quantifying the lipid peroxidation product ethane in breath. Serum vitamin E, a lipid soluble antioxidant, concentrations was also assessed. While MNA response was correlated with breath ethane concentrations, the expected relationship between the two measures was not observed. Instead a positive relationship between them suggests that some patients with schizophrenia have impaired fatty acid utilization leading to both diminished lipid peroxidation and cyclo-oygenation. This was not related to vitamin E concentrations, however, suggesting that lipid soluble anti-oxidant availability did not underlie our findings. Our data shed further light on the mechanism of impaired MNA response in schizophrenia and support the notion that this occurs consequent to a change in lipid metabolism.

Non-Immunosuppressant Medication Use in Heart Transplant Patients: A Guide for Pharmacists  [PDF]
Gregory Egan, Glen J. Pearson
Pharmacology & Pharmacy (PP) , 2014, DOI: 10.4236/pp.2014.510107
Abstract: For heart transplant patients, there are a number of non-immunosuppressant medications that are routinely prescribed to mitigate the side-effects of immunosuppression, treat the related complications, and improve long-term survival. This review focuses on the medications used to prevent and manage cardiac allograft vasculopathy (CAV), hypertension, dyslipidemia and osteoporosis. The rationale and evidence supporting their use are summarized and the immunosuppressant drugs are only discussed briefly, as they relate to each of these medical issues. Pharmacy practitioners are likely to encounter patients post-cardiac transplant in a variety of clinical settings; therefore, a concise appreciation of the principles for the long-term medical management of these patients is important when providing collaborative care.
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