oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

4 ( 1 )

2019 ( 5 )

2018 ( 65 )

2017 ( 54 )

Custom range...

Search Results: 1 - 10 of 27752 matches for " Glaucia Mendes Souza "
All listed articles are free for downloading (OA Articles)
Page 1 /27752
Display every page Item
Circadian Rhythms of Sense and Antisense Transcription in Sugarcane, a Highly Polyploid Crop
Carlos Takeshi Hotta, Milton Yutaka Nishiyama, Glaucia Mendes Souza
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0071847
Abstract: Commercial sugarcane (Saccharum hybrid) is a highly polyploid and aneuploid grass that stores large amounts of sucrose in its stem. We have measured circadian rhythms of sense and antisense transcription in a commercial cultivar (RB855453) using a custom oligoarray with 14,521 probes that hybridize to sense transcripts (SS) and 7,380 probes that hybridize to antisense transcripts (AS).We estimated that 32% of SS probes and 22% AS probes were rhythmic. This is a higher proportion of rhythmic probes than the usually found in similar experiments in other plant species. Orthologs and inparalogs of Arabidopsis thaliana, sugarcane, rice, maize and sorghum were grouped in ortholog clusters. When ortholog clusters were used to compare probes among different datasets, sugarcane also showed a higher proportion of rhythmic elements than the other species. Thus, it is possible that a higher proportion of transcripts are regulated by the sugarcane circadian clock. Thirty-six percent of the identified AS/SS pairs had significant correlated time courses and 64% had uncorrelated expression patterns. The clustering of transcripts with similar function, the anticipation of daily environmental changes and the temporal compartmentation of metabolic processes were some properties identified in the circadian sugarcane transcriptome. During the day, there was a dominance of transcripts associated with photosynthesis and carbohydrate metabolism, including sucrose and starch synthesis. During the night, there was dominance of transcripts associated with genetic processing, such as histone regulation and RNA polymerase, ribosome and protein synthesis. Finally, the circadian clock also regulated hormone signalling pathways: a large proportion of auxin and ABA signalling components were regulated by the circadian clock in an unusual biphasic distribution.
The sugarcane signal transduction (SUCAST) catalogue: prospecting signal transduction in sugarcane
Souza Glaucia Mendes,Simoes Ana Carolina Quirino,Oliveira Katia Cristina,Garay Humberto Miguel
Genetics and Molecular Biology , 2001,
Abstract: EST sequencing has enabled the discovery of many new genes in a vast array of organisms, and the utility of this approach to the scientific community is greatly increased by the establishment of fully annotated databases. The present study aimed to identify sugarcane ESTs sequenced in the sugarcane expressed sequence tag (SUCEST) project (http://sucest.lad.ic.unicamp.br) that corresponded to signal transduction components. We also produced a sugarcane signal transduction (SUCAST) catalogue (http://sucest.lad.ic.unicamp.br/private/mining-reports/QG/QG-mining.htm) that covered the main categories and pathways. Expressed sequence tags (ESTs) encoding enzymes for hormone (gibberellins, ethylene, auxins, abscisic acid and jasmonic acid) biosynthetic pathways were found and tissue specificity was inferred from their relative frequency of occurrence in the different libraries. Whenever possible, transducers of hormones and plant peptide signaling were catalogued to the respective pathway. Over 100 receptors were found in sugarcane, which contains a large family of Ser/Thr kinase receptors and also photoreceptors, histidine kinase receptors and their response regulators. G-protein and small GTPases were analyzed and compared to known members of these families found in mammalian and plant systems. Major kinase and phosphatase pathways were mapped, with special attention being given to the MAP kinase and the inositol pathway, both of which are well known in plants.
mRNA expression and release of interleukin-8 induced by serum amyloid A in neutrophils and monocytes
Fernanda Pereira Ribeiro,Cristiane Jaciara Furlaneto,Elaine Hatanaka,Wesley Bueno Ribeiro,Glaucia Mendes Souza,Marco A. Cassatella,Ana Campa
Mediators of Inflammation , 2003, DOI: 10.1080/0962935031000134897
Abstract: The acute phase response is a systemic reaction to inflammatory processes characterized by multiple physiological adaptations, including the hepatic synthesis of acute-phase proteins. In humans, serum amyloid A (SAA) is one of the most prominent of these proteins. Despite the huge increase of serum levels of SAA in inflammation, its biological role remains to be elucidated, even though SAA is undoubtedly active in neutrophils. In a previous study, we reported that SAA induces the release of tumor necrosis factor-α, interleukin (IL)-1β and IL-8 from human blood neutrophils. Here, we extend our earlier study, focusing on the effect of SAA on neutrophil IL-8 transcription and on the signaling pathways involved. We demonstrate herein that SAA, in relatively low concentrations (0.4-100 μg/ml) compared with those found in plasma in inflammatory conditions, induces a dose-dependent release of IL-8 from neutrophils. The p38 mitogen-activated protein kinase inhibitor SB 203580 inhibits the IL-8 mRNA expression and the release of protein from neutrophils. The release of IL-8 from SAA-stimulated neutrophils is strongly suppressed by the addition of N-acetyl-l-cysteine, α-mercaptoethanol, glutathione, and dexamethasone. SAA also induces IL-8 expression and release from monocytes. In conclusion, SAA appears to be an important mediator of the inflammatory process, possibly contributing to the pool of IL-8 produced in chronic diseases, which may play a role in degenerative diseases.
The sugarcane signal transduction (SUCAST) catalogue: prospecting signal transduction in sugarcane
Souza, Glaucia Mendes;Simoes, Ana Carolina Quirino;Oliveira, Katia Cristina;Garay, Humberto Miguel;Fiorini, Leonardo Costa;Gomes, Felipe dos Santos;Nishiyama-Junior, Milton Yutaka;Silva, Aline Maria da;
Genetics and Molecular Biology , 2001, DOI: 10.1590/S1415-47572001000100005
Abstract: est sequencing has enabled the discovery of many new genes in a vast array of organisms, and the utility of this approach to the scientific community is greatly increased by the establishment of fully annotated databases. the present study aimed to identify sugarcane ests sequenced in the sugarcane expressed sequence tag (sucest) project (http://sucest.lad.ic.unicamp.br) that corresponded to signal transduction components. we also produced a sugarcane signal transduction (sucast) catalogue (http://sucest.lad.ic.unicamp.br/private/mining-reports/qg/qg-mining.htm) that covered the main categories and pathways. expressed sequence tags (ests) encoding enzymes for hormone (gibberellins, ethylene, auxins, abscisic acid and jasmonic acid) biosynthetic pathways were found and tissue specificity was inferred from their relative frequency of occurrence in the different libraries. whenever possible, transducers of hormones and plant peptide signaling were catalogued to the respective pathway. over 100 receptors were found in sugarcane, which contains a large family of ser/thr kinase receptors and also photoreceptors, histidine kinase receptors and their response regulators. g-protein and small gtpases were analyzed and compared to known members of these families found in mammalian and plant systems. major kinase and phosphatase pathways were mapped, with special attention being given to the map kinase and the inositol pathway, both of which are well known in plants.
KeaA, a Dictyostelium kelch-domain protein that regulates the response to stress and development
Luciana Mantzouranis, Raquel Bagattini, Glaucia M Souza
BMC Developmental Biology , 2010, DOI: 10.1186/1471-213x-10-79
Abstract: A mutation in keaA suppresses the hypersensitivity to oxidative and nitrosoative stresses but not the faster growth phenotype of yakA- cells. The growth profile of keaA deficient cells indicates that this gene is necessary for growth. keaA deficient cells are more resistant to nitrosoative and oxidative stress and keaA is necessary for the production and detection of cAMP. A morphological analysis of keaA deficient cells during multicellular development indicated that, although the mutant is not absolutely deficient in aggregation, cells do not efficiently participate in the process. Gene expression analysis using cDNA microarrays of wild-type and keaA deficient cells indicated a role for KeaA in the regulation of the cell cycle and pre-starvation responses.KeaA is required for cAMP signaling following stress. Our studies indicate a role for kelch proteins in the signaling that regulates the cell cycle and development in response to changes in the environmental conditions.The social amoebae Dictyostelium discoideum grows as a unicellular organism feeding on soil bacteria. Upon nutrient depletion the amoebae survive by differentiating into spores in a developmental process where 105 cells aggregate and differentiate to form a 1 mm tall organism with distinct tissues. cAMP is a molecule with multiple functions during the entire life cycle, acting both extracellularly as a chemoattractant and intracellularly as a regulator of gene expression. The protein kinase YakA has been implicated in the transition from growth to development, playing a crucial role in this process. YakA is an effector of the gene expression changes that follow starvation including the down-regulation of vegetative genes, the up-regulation of the cAMP-dependent protein kinase, pkaC, the adenylyl cyclase acaA, and the cAMP receptor carA. During growth YakA regulates the cell cycle, and the survival to oxidative, nitrosoative and thermal stresses. YakA impinges on the cell cycle by regulating the int
Hemodiálise: estilo de vida e a adapta??o do paciente
Barbosa, Genesis de Souza;Valadares, Glaucia Valente;
Acta Paulista de Enfermagem , 2009, DOI: 10.1590/S0103-21002009000800014
Abstract: objective: to identify and describe how patients on hemodialysis cope with their disease regarding changes in attitudes, behaviors, and practices of activities of daily life. methods: this qualitative study, guided by grounded theory, was conducted among patients attending the association of renal transplant of rio de janeiro. the sample comprised 10 patients. results: the analysis suggested that the patients went through denial, negative thoughts, and social adjustment to achieve adaptation by constructing a new life style. conclusion: nursing interventions must go beyond the physical and biological patients' needs to include social and psychological approaches that might be effective in improving the quality of life of patients on hemodialysis.
Experimentando atitudes e sentimentos: o cotidiano hemodialítico como base para o cuidar em enfermagem
Barbosa, Genesis de Souza;Valadares, Glaucia Valente;
Escola Anna Nery , 2009, DOI: 10.1590/S1414-81452009000100003
Abstract: this study aims to: discuss the relation of the patient's confrontation on hemodialysis in terms of possibilities for nursing care. adopted as a theoretical reference the vision of the individual and systemic concepts of confrontation. the path traveled was the methodology of qualitative research, using the basic principles of grounded theory. the scenario of the study was an association of kidney and transplanted from rio de janeiro state. the participants of the research subjects were dependent on dialysis involved in this association. to rescue the data were taken by participant observation and semi-structured in depth. the information was analyzed, considering the basic procedures relevant to grounded theory: open coding, coding axial and coding selective. among many things, the study points to the relationship of interdependence of knowledge and sensitivity to ensure that the care provided is based on the systemic view of the individual.
Desvelando o saber/ fazer sobre diagnósticos de enfermagem: experiência vivida em neurocirurgia oncológica
Souza, Angeli Soares de;Valadares, Glaucia Valente;
Revista Brasileira de Enfermagem , 2011, DOI: 10.1590/S0034-71672011000500014
Abstract: article extracted from a master's dissertation whose objective was to characterize the interaction of nurses with nursing diagnoses in neurosurgical oncology, considering behaviors, expressions, attitudes and practices. the participants were sixteen nurses who work with equal or more than five years in neurosurgical oncology at the national cancer institute. the symbolic interactionism was used as the theoretical framework, and the grounded theory, as a methodological approach. the findings indicate that the nurse is unveiling possibilities of caring for the client of neurosurgical oncology, not only in the perspective of suffering, but especially from the perspective of existential care, covering their needs and singularities, and respecting their limitations.
Menstrual cramps: A new therapeutic alternative care through medicinal plants  [PDF]
Andrieli Daiane Zdanski de Souza, Marjoriê da Costa Mendieta, Glaucia Fragoso Hohenberger, Marcelo Melo Silva, Teila Ceolin, Rita Maria Heck
Health (Health) , 2013, DOI: 10.4236/health.2013.57149
Abstract:

The study aims to know the medicinal plants used by farming families of communities in four municipalities of the south region of RS for the relief of menstrual cramps. It is a descriptive study that analyzed qualitative data. The subjects were 19 farmers from Cangu?u, Arroio do Padre, Morro Redondo and Pelotas. Data were collected from January and May the 2009, through semistructured interviews. Eight plants used for relieve menstrual cramps were cited. This research showed that the popular knowledge of farmers is consistent, in 100%, with the search made in the scientific literature. It is evident that the plants Apium sp., Plectranhus sp., Cinnamomum sp., Chenopodium ambrostoides, Origamun sp., Petroselimum crispum have evidence in the scientific literature, showing that the individuals in this study use the medicinal plants suitable for their purpose.

Marchando com a família, com Deus e pela liberdade: o"13 de Mar?o" das direitas
Mendes, Ricardo Antonio Souza;
Varia Historia , 2005, DOI: 10.1590/S0104-87752005000100012
Abstract: since jango's inauguration in 1961, a growing campaign, created by the government, which had just begun and guided by various groups of the right, focused the likelihood of the country to adopt the communism. through the means of communication - newspapers, television, cinema, as well as through limited circulation journals which were very expressive -, the groups tried to show that it was being articulated, from the republic presidency, the break of the constitutional legality. nevertheless it was the radicalism of certain speeches at "central do brasil assembly. that brought up the big catalytic agent of the adherence of an important component of the society surrounding the proposals of the several actors who articulated jo?o goulart's overthrow. the "marcha da família com deus pela liberdade" (the family with god for liberty march) embodied this relation showing that to a big amount of brazilians the defence of the constitutional legality was not in the hands of the government any longer. on the contrary, for those who participated of the "march", it presented itself under the banner of the people who articulated the blow.
Page 1 /27752
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.