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Search Results: 1 - 10 of 1449 matches for " Gisela; Ballester Santovenia "
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Frecuencia de la leucemia promielocítica en Cuba
Milanés Roldán,María Teresa; Hernández Ramírez,Porfirio; Svarch Guerchicoff,Eva; Martínez Antu?a,Gisela; Ballester Santovenia,José M;
Revista Cubana de Hematolog?-a, Inmunolog?-a y Hemoterapia , 2001,
Abstract: 1 112 patients with al (acute leukemias) from all over the country (714 adults and 398 children under 15) were analyzed. 637 (554 adults and 83 children) had aml (acute myeloid leukemia) and 98 cases (72 adults and 26 children) were diagnosed apl (acute promyelocytic leukemia). the apl accounted for 8.9 % of all the cases of al in adults and 6.5 % of all the cases of al in children. its frequency in relation to the total of cases of aml with no age limit represented 15.3 %. however, when this frequency was analyzed by age group, it was observed that it was 31.3 % in children, whereas in adults it was just 13 %. in our study, it was possible to prove that similarly to what happens in certain geographic regions and population groups, there is an increase of the frequency of apl in children compared with the data found in the previous literature. our results stress the need to consider by separate this type of leukemia in children and adults, since its analysis in only one group may occult variations in its frequency
El Programa de Medicina Transfusional de Cuba
Santovenia,José M. Ballester;
Revista Panamericana de Salud Pública , 2003, DOI: 10.1590/S1020-49892003000200019
Abstract: cuba's transfusion medicine program (tmp) is a subsystem of the country's national health system. the tmp's objective is to ensure hemotherapy with blood that is safe and sufficient for all the individuals who need it. the tmp subsystem is made up of the national commission on transfusion medicine, the institute of hematology and immunology, 37 clinical services, 44 blood banks, 120 collection centers, 19 mobile units, and 37 blood certification laboratories. additional facilities include a laboratory for plasma separation, a laboratory that produces leukocyte interferon and transfer factor, and two laboratories that produce reagents for blood classification and blood diagnosis systems. in cuba, blood donation is voluntary. since 1997 approximately 5% of the population per year has donated blood, thus meeting the goal recommended by the pan american health organization of one voluntary blood donation annually for every 20 persons. during 2002, 563 204 blood donations were received, and there were 445 898 transfusions of blood or blood components. all donations are individually screened for hiv 1 and 2, hepatitis b, hepatitis c, and syphilis, thus meeting the country's current regulations. in 2002 these screening measures led to discarding, respectively, 0.12%, 0.60%, 0.71%, and 1.8% of the blood donations. although the prevalence of human t-cell lymphotropic virus i and ii in cuba is very low, this test will soon be added to the screening process.
El Programa de Medicina Transfusional de Cuba
Santovenia José M. Ballester
Revista Panamericana de Salud Pública , 2003,
Abstract: Cuba's Transfusion Medicine Program (TMP) is a subsystem of the country's National Health System. The TMP's objective is to ensure hemotherapy with blood that is safe and sufficient for all the individuals who need it. The TMP subsystem is made up of the National Commission on Transfusion Medicine, the Institute of Hematology and Immunology, 37 clinical services, 44 blood banks, 120 collection centers, 19 mobile units, and 37 blood certification laboratories. Additional facilities include a laboratory for plasma separation, a laboratory that produces leukocyte interferon and transfer factor, and two laboratories that produce reagents for blood classification and blood diagnosis systems. In Cuba, blood donation is voluntary. Since 1997 approximately 5% of the population per year has donated blood, thus meeting the goal recommended by the Pan American Health Organization of one voluntary blood donation annually for every 20 persons. During 2002, 563 204 blood donations were received, and there were 445 898 transfusions of blood or blood components. All donations are individually screened for HIV 1 and 2, hepatitis B, hepatitis C, and syphilis, thus meeting the country's current regulations. In 2002 these screening measures led to discarding, respectively, 0.12%, 0.60%, 0.71%, and 1.8% of the blood donations. Although the prevalence of human T-cell lymphotropic virus I and II in Cuba is very low, this test will soon be added to the screening process.
Impacto del desarrollo del Instituto de Hematología e Inmunología en las Ciencias Médicas cubanas Impact of the development of the Institute of Hematology and Immunology at the Cuban Medical Sciences
José M . Ballester-Santovenia
Revista Cubana de Hematolog?-a, Inmunolog?-a y Hemoterapia , 2012,
Abstract:
El sistema inmunológico: comentarios de interés básico The immunological system: comments of basic interest
José M Ballester Santovenia,Consuelo Macías Abraham
Revista Cubana de Hematolog?-a, Inmunolog?-a y Hemoterapia , 2003,
Abstract:
Aplicacion de la medicina nuclear en el Instituto de Hematología e Inmunología: Resultados más relevantes
Fundora Sarraff,Teresa A; Fernández Delgado,Norma; Gautier du Défaix Gómez,Hortensia; Macías Abraham,Consuelo; del Valle Pérez,Lázaro; Martínez Antu?a,Gisela; Hernández Ramírez,Porfirio; Ballester Santovenia,José M;
Revista Cubana de Hematolog?-a, Inmunolog?-a y Hemoterapia , 2004,
Abstract: the application of nuclear medicine by several multidisciplinary scientific teams working at the institute of hematology and immunology has helped in the development of both specialties in cuba thanks to the high quality of the techniques used and to the results achieved that are similar to other services in the developed countries. the above-mentioned has been recognized by the international atomic energy organization. hundreds of patients have benefited from the diagnosis and the follow-up of hematological, immune diseases and other types of illness, which has made it possible to improve their quality of life. original results has been reached in diagnosis of policytemia, anemia, myeolodisplastic syndromes and other khematologicalk, immunological disorders, neuritis as well as in those individuals affected by nuclear accidents; also impact results have been attained with the application of this technique in the field of molecular biology and in the prenatal diagnosis of sickle cell anemia, and with the introduction of state-of-the art techniques such as radiosinoviortesis
Reacciones transfusionales en el Hospital Docente Provincial “Comandante Faustino Pérez” de la provincia de Matanzas Transfusion reactions at “Comandante Faustino Pèrez” Provincial University Hospital in the province of Matanzas
Hilda M Silva Ballester,Mercedes Rojas Zú?iga,Ariadna González Lorenzo,José M Ballester Santovenia
Revista Cubana de Hematolog?-a, Inmunolog?-a y Hemoterapia , 2007,
Abstract: A partir del a o 2003, en el Hospital Docente Provincial “Comandante Faustino Pérez” se inició el control y análisis de los efectos adversos de la transfusión de sangre, mediante el reporte y estudio de todas las reacciones transfusionales, para conocer su frecuencia, tipo y gravedad, así como su relación con el componente utilizado, los días de extraído y el sexo del receptor. Se reportaron los errores detectados y subsanados antes del proceder. Este estudio se realizó bajo la asesoría y control del Banco de Sangre Provincial “Minerva Duarte”, como parte de la vigilancia sobre los productos sanguíneos y la cadena transfusional, con el objetivo de disminuir los efectos adversos e incrementar la seguridad transfusional. Los datos obtenidos demuestran disminución del número de reacciones adversas, de 52 en el 2002 a 14 en el 2005. Las más frecuentes fueron la febril no hemolítica y las alérgicas; la más grave resultó la contaminación bacteriana. Los errores más frecuentes subsanados antes de la transfusión fueron por equivocación del grupo en la bolsa a transfundir. El componente que más reacciones originó fue el concentrado de hematíes y el sexo femenino fue el que más reacciones presentó. El estudio permitió la adopción de medidas correctivas y preventivas para disminuir las reacciones e incrementar la seguridad transfusional en el centro hospitalario. From 2003 on, it was started the control and analysis of the adverse effects of blood transfusion at “Comandante Faustino Pérez” Provincial University Hospital by the report and study of all the transfusion reactions in order to know their frequency, type and severity, as well as their relation to the component used, the date of the extraction, and the sex of the recipient. The errors detected and corrected before the procedure were reported. This study was conducted under the counselling and control of “Minerva Duarte” Provincial Blood Bank as part of the vigilance of the blood products and the transfusion chain aimed at reducing the adverse effects and at increasing transfusion safety. The data obtained showed a decrease of the number of adverse reactions from 52, in 2002, to 14, in 2005. The most common reactions were the non-hemolytic febrile reactions and the allergic reactions, whereas the most serious was bacterial contamination. The most frequent amended mistakes before transfusion were those made by the group with the transfusion bag. The packed cells proved to be the component that originated the greatest amount of reactions. Females had more reactions. The study allowed to take corrective and p
Desarrollo de un sistema de hemovigilancia en el Hospital “Iluminado Rodríguez”, del Municipio Jagüey Grande, Matanzas Development of a system of hemosurveillance in “Iluminado Rodríguez” Hospital of Jagüey Grande municipality, Matanzas
Hilda M Silva Ballester,José A López Pena,Esperanza Cárdenas Rodríguez,José M Ballester Santovenia
Revista Cubana de Hematolog?-a, Inmunolog?-a y Hemoterapia , 2006,
Abstract: En la etapa comprendida entre enero de 2003 y diciembre de 2005, se desarrolló un sistema de hemovigilancia en nuestra provincia, con el objetivo de incrementar la seguridad transfusional mediante la reducción de los efectos adversos de la transfusión y el uso adecuado de la sangre y sus componentes. En el Hospital Municipal “Iluminado Rodríguez” de Jagüey Grande, se realizaron las siguientes acciones: reporte de las reacciones transfusionales, creación del Comité Hospitalario de Hemovigilancia (que permitió tener un control más eficiente del uso de sangre y componentes) y establecimiento de un sistema rápido de alerta que permite tomar decisiones acertadas en un mínimo de tiempo. Se implementó un programa de capacitación continua para profesionales y técnicos que estuvieran directamente relacionados con el Programa de Sangre, con el fin de elevar su nivel científico técnico y se desarrolló una campa a de reclutamiento y retención de donantes. Los resultados de estas acciones demuestran la eficiencia del sistema: incremento de la seguridad transfusional por la disminución de las reacciones transfusionales de 15 en el a o 2002 a 6 en el 2005; ausencia de efectos adversos graves, erradicación del consumo de sangre total, disminución del uso de glóbulos y plasma, elevación del nivel de capacitación en el tema en profesionales y técnicos y aporte de sangre segura a la población From January 2003 to December 2005, a system of hemosurveillance was developed in our country aimed at increasing the transfusional safety by reducing the adverse effects of transfusion and the adequate use of blood and its components. A report of the transfusional reactions was made, a Hospital Committee of Hemosurveillance was created (that allowed to have a more efficient use of the blood and its components), and a rapid system of alert that make posible to take appropiate decisions in a minimum of time was established at this hospital. A continual upgrading program was implemented for professionasl and technicians that were directly related to the Blood Program in order to enhance their scientific and technical level, and a campaign of recruitment and retention of donors was carried out. The results of these actions show the efficiency of the system: increase of the transfusional safety through the reduction of transfusional reactions from 15, in 2002, to 6, in 2005; absence of serious adverse effects; erradication of the consumption of total blood; decrease of the use of red blood cells and plasma; elevation of the upgrading level on this topic among professionals and technician
Consumo de sangre en operaciones electivas de cirugía general
Fuentes Valdés,Edelberto; Díaz Calderín,José M; Ballester Santovenia,Adalberto;
Revista Cubana de Cirug?-a , 1996,
Abstract: a study on blood consumption in elective operations of general surgery is presented. 7,7 % of the patients who underwent surgery were transfused. the greatest number of units transfused was that of gynecological operations with 63 and of them abdominal hysterectomies required the most with 58 in 184 operations, for 31,5 %. pulmonary lobectomies, partial cholectomies, miles operation, hepatic resections and subtotal gastrectomies are also important due to the amount of units consumed and to the percentage of patient transfused. the highest average of units used in transfused patients was observed in total esophagectomies with 9; whipple's operation, 5; hepatic resections 4,5; pleurectomy and decortication, 3; subtotal gastrectomies, 2,9; and abdominal hysterectomy, 2,03. the main criteria used for indicating transfusion were transoperative bleeding and preoperative anaemia
Uso del factor VII activado recombinante en pacientes no hemofílicos en Cuba Use of the recombinant activated factor VII in non-hemophilic patients in Cuba
Olga Agramonte Llanes,Delfina Almagro Vázquez,José M Ballester Santovenia,Dunia Castillo González
Revista Cubana de Hematolog?-a, Inmunolog?-a y Hemoterapia , 2008,
Abstract: El factor VII activado recombinante (rFVIIa, NovoSeven ) ha sido utilizado en el tratamiento de los sangramientos en los pacientes hemofílicos con inhibidores. También ha sido usado para el tratamiento de los sangramientos no controlados asociados con trauma o cirugía. Se describe el tratamiento con rFVIIa en 7 pacientes no hemofílicos con un amplio rango de eventos hemorrágicos: 3 a quienes se les realizó trasplante hepático y presentaron sangramiento postrasplante sin respuesta al tratamiento convencional; 1 con aplasia medular severa y hemorragia retiniana; 1 con enfermedad de Rendú-Osler-Weber, quien tuvo un sangramiento gastrointestinal severo; y 1 paciente con manifestaciones hemorrágicas cutáneas y pulmonares debido a una enfermedad viral. La dosis de rFVIIa utilizada fue entre 90_100 μg/kg de peso, tanto para el tratamiento profiláctico como terapéutico. El rFVII activado alcanzó una hemostasia efectiva en todos los casos. Consideramos que el FVII activado puede ser aplicado cuando la combinación de los hemoderivados y los avances quirúrgicos han fallado en el control de los sangramientos que ponen en peligro la vida The recombinant activated factor VII (rFVIIa, NovoSeven ) has been used in the treatment of bleedings in hemophilic patients with inhibitors. It has also been used for treating uncontrolled bleedings associated with trauma or surgery. The treatment with rFVIIa in 7 non-hemophilic patients with a wide range of hemorrhagic events is described: 3 that underwent liver transplant and presented posttransplant without response to the conventional treatment; 1 with severe medullary aplasia and retinal hemorrhage; 1 with Rendú-Osler-Weber's disease that had severe gastrointestinal bleeding; and 1 patient with cutaneous and pulmonary hemorrhagic manifestations due to a viral disease. The dose of rFVIIa used was between 90 and 100 μg/kg of weight, both for the prophylactic and therapeutic treatment. The activated rFVII reached an effective hemostasis in all cases. We consider that the activated FVII may be applied when the combination of hemoderivatives and the surgical advances have failed in the control of bleedings endangering life
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