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Search Results: 1 - 10 of 5636 matches for " Giovanni Mazzotta "
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Attention deficit hyperactivity disorder secondary to lesion of the basal ganglia  [PDF]
Giovanni Mazzotta, Lucia Lucia Cirulli, Marco Sposato, Domenico Serino
World Journal of Neuroscience (WJNS) , 2012, DOI: 10.4236/wjns.2012.21007
Abstract: Attention Deficit Hyperactivity Disorder (ADHD) is a childhood onset autoregulation disorder characterized by attention deficit, hyperactivity and/or impul- siveness, which results in social and academic functional impairment. ADHD has a complex aetiology: along with genetic factors, anomalies in several cere-bral districts have been reported. We describe the case of a 9 year old boy with glucose-6-phosphate dehydrogenase deficiency in association with memory, behavioural and attentive disabilities. The patient’s clinical history is characterized by cerebral stroke at 3 years of age during a febrile episode, resulted in slight hemiparesis. Neuroimaging revealed a cystic lesion in the anterior portion of the right lenticular nucleus. Neuropsychological and psychiatric assess- ment evidenced alterations of executive functions. Diagnosis of ADHD secondary to lesion of the basal ganglia was made. We report the patient’s clinical profile in the light of current evidence pointing towards dysfunction of the basal ganglia as a crucial aetiological factor in memory and executive function impairment.
The renin angiotensin system in the development of cardiovascular disease: role of aliskiren in risk reduction
Paolo Verdecchia,Fabio Angeli,Giovanni Mazzotta,Giorgio Gentile
Vascular Health and Risk Management , 2008,
Abstract: Paolo Verdecchia1, Fabio Angeli1, Giovanni Mazzotta1, Giorgio Gentile2, Gianpaolo Reboldi21Department of Cardiology, Clinical Research Unit ‘Preventive Cardiology’, Hospital ‘Santa Maria della Misericordia’, and Fondazione Umbra Cuore e Ipertensione – AUCI Onlus, Perugia, Italy; 2Department of Internal Medicine University of Perugia, ItalyAbstract: An association has been shown between plasma renin activity (PRA) and the risk of cardiovascular disease. There is also evidence that angiotensin II exerts detrimental effects on progression and instabilization of atherosclerotic plaque. The renin-angiotensin system (RAS) can be inhibited through inhibition of angiotensin I (Ang I) generation from angiotensinogen by direct renin inhibitors, inhibition of angiotensin II (Ang II) generation from angiotensin I by angiotensin-converting enzyme inhibitors and finally by direct inhibition of the action of Ang II receptor level. Aliskiren, the first direct renin inhibitor to reach the market, is a lowmolecular-weight, orally active, hydrophilic nonpeptide. Aliskiren blocks Ang I generation, while plasma renin concentration increases because the drugs blocks the negative feed-back exerted by Ang II on renin synthesis. Because of its long pharmacological half-life, aliskiren is suitable for once-daily administration. Its through-to-peak ratio approximates 98% for the 300 mg/day dose. Because of its mechanism of action, aliskiren might offer the additional opportunity to inhibit progression of atherosclerosis at tissue level. Hypertension is an approved indication for this drug, which is also promising for the treatment of heart failure. The efficacy of this drug in reducing major clinical events is being tested in large ongoing clinical trials.Keywords: plasma renin activity, renin angiotensin system, aliskiren, angiotensinogen, renin, hypertension, heart failure, diabetes
Which anatomy books should a medical student choose?
Paolo Mazzotta
University of Toronto Medical Journal , 2001, DOI: 10.5015/utmj.v78i3.1057
The Relationship Between Medical Education and The Pharmaceutical Industry - Good Medicine or a Bitter Pill to Swallow?
Paolo Mazzotta,Julianna Borbely
University of Toronto Medical Journal , 2002, DOI: 10.5015/utmj.v79i2.889
Polluting Productions and Sustainable Economic Growth: A Local Stability Analysis  [PDF]
Giovanni Bella
Journal of Service Science and Management (JSSM) , 2009, DOI: 10.4236/jssm.2009.21007
Abstract: The aim of this paper is to analyze the link between natural capital and economic growth, in a Romer-type economy characterized by dirty emissions in the production process, and to examine the conditions under which a sustainable growth, which implies a decreasing level of dirty emissions, might be both feasible and optimal. This work is close to Aghion-Howitt (1998) with some more general specifications, in particular regarding the structure of preferences and the technological sector. We also deeply study the transitional dynamics of this economy towards the steady state, and conclude that a determinate saddle path sustainable equilibrium can be reached even in presence of a long run positive level of polluting emissions, thanks to a growing level of new home-made inventories, without whom some indetermi-nacy problems are likely to emerge.
Contestability and Collateral in Credit Markets with Adverse Selection  [PDF]
Giovanni Cesaroni
Theoretical Economics Letters (TEL) , 2012, DOI: 10.4236/tel.2012.21010
Abstract: The work discusses a basic proposition in the theory of competition in markets with adverse selection. By working out the sequence of market transactions, we show that the effectiveness of collateral in avoiding equilibrium rationing depends on an assumption of uncontestability of the loan market. If contestability is restored to its proper place, the sepa- ration of borrower by means of sufficient collateral does not impede the emergence of credit rationing, which results from a coordination failure among risk-neutral banks. As a consequence, even in a risk-neutral environment with suitable endowments, the use of collateral in credit contracts could not be a socially efficient screening-device. Our conclu- sion on rationing does not stand in contrast with a general result from Gale.
Endogenous Discounting and Global Indeterminacy  [PDF]
Giovanni Bella
Modern Economy (ME) , 2013, DOI: 10.4236/me.2013.411080

This paper innovates the literature on endogenous discounting in environmental economics, by studying the global properties of the equilibrium outside the small neighborhood of the steady state. The internalization of individual consumption in the social discount rate is rich of powerful consequences from the economic point of view, for it leads to a qualitative change in the steady state and its transitional dynamics, so that the perfect foresight equilibrium may not be unique, and thus both local and global indeterminacy can eventually emerge. The main implication for decision making is that if indeterminacy occurs, public policies become not sufficient to drive the economy towards the long-run equilibrium. In particular, we show that the onset of parametric restrictions for which both global indeterminacy in the full R3 vector field, and a quasi-periodic dynamics with trajectories wrapped around an invariant torus, may eventually emerge.

Addressing Biodiversity Conservation Methods with Fagus sylvatica Genetic Indicators  [PDF]
Giovanni Figliuolo
Open Journal of Genetics (OJGen) , 2014, DOI: 10.4236/ojgen.2014.42017

Species biological history revealed by genetic indicators can provide guidelines for long-term biodiversity conservation in Natura 2000 network. Fagus sylvatica is the keystone species which regulates in the Mediterranean Eco-Region ecosystem structure, function and composition. Six hundred fifty nine F. sylvatica individuals have been sampled across 20 sites of European interest in Southern Italy and analyzed at 5 microsatellite loci. For sites marked by both maximum heterozygosity (Ho) and minimum heterozygote deficit (Fis) (IT9210210, ITA070099, IT9210205 and IT9220075) it is suggested to avoid impacts by adopting very conservative measures. Promoting migration processes (pollen flow and seed flow) would be appropriate where it has been monitored low heterozygosity and high genetic disequilibrium. Margin effect due to dryness should be buffered with appropriate belts of thermophilus broad leaved tree species.

Palmar Intertriradial Ridge Counts in Sardinians  [PDF]
Giovanni Floris
Advances in Anthropology (AA) , 2015, DOI: 10.4236/aa.2015.53012
Abstract: Palmar intertriradial ridge counts (a-b, b-c, c-d, a-d) in 260 males and 260 females of Sardinian origin were considered. Bilateral and sex differences, correlation coefficients, skewness and kurtosis of the four distributions and an index of asymmetry were calculated. There are no sex differences, ridge counts show positive and almost always significant correlations. The a-d ridge count shows a normal distribution in both sexes.
Only One Goal: Economic Growth. How Can Environmentalism Survive in the 21st Century?  [PDF]
Giovanni Capulli
Advances in Applied Sociology (AASoci) , 2015, DOI: 10.4236/aasoci.2015.56017
Abstract: This paper is aimed to explore environmentalism in the 21st century: this broad philosophy has to overcome its limits in order to survive in a society where there seems to be only one goal, the economic growth. In the first part of the essay, I want to analyze the present condition as a result of a weak environmental consciousness. In the second part of the essay, I want to describe and compare two mainstreams of present environmentalism: de-growth theory and sustainable development.
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