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Search Results: 1 - 10 of 2621 matches for " Giovanna Megumi Ishida Tedesco "
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Sistema de transporte rodoviário de cargas: uma proposta para sua estrutura e elementos
Thaís Maria de Andrade Villela,Giovanna Megumi Ishida Tedesco
Transportes , 2011,
Abstract: Sistema de transporte rodoviário de cargas: uma proposta para sua estrutura e elementos
Blue-Violet Laser Modification of Titania Treated Titanium: Antibacterial and Osteo-Inductive Effects
Takanori Kawano, Widyasri Prananingrum, Yuichi Ishida, Takaharu Goto, Yoshihito Naito, Megumi Watanabe, Yoritoki Tomotake, Tetsuo Ichikawa
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0084327
Abstract: Background Many studies on surface modifications of titanium have been performed in an attempt to accelerate osseointegration. Recently, anatase titanium dioxide has been found to act as a photocatalyst that expresses antibiotic properties and exhibits hydrophilicity after ultraviolet exposure. A blue-violet semiconductor laser (BV-LD) has been developed as near-ultraviolet light. The purpose of this study was to investigate the effects of exposure to this BV-LD on surface modifications of titanium with the goal of enhancing osteoconductive and antibacterial properties. Methods The surfaces of pure commercial titanium were polished with #800 waterproof polishing papers and were treated with anatase titania solution. Specimens were exposed using BV-LD (λ = 405 nm) or an ultraviolet light-emitting diode (UV-LED, λ = 365 nm) at 6 mW/cm2 for 3 h. The surface modification was evaluated physically and biologically using the following parameters or tests: surface roughness, surface temperature during exposure, X-ray diffraction (XRD) analysis, contact angle, methylene blue degradation tests, adherence of Porphyromonas gingivalis, osteoblast and fibroblast proliferation, and histological examination after implantation in rats. Results No significant changes were found in the surface roughness or XRD profiles after exposure. BV-LD exposure did not raise the surface temperature of titanium. The contact angle was significantly decreased, and methylene blue was significantly degraded. The number of attached P. gingivalis organisms was significantly reduced after BV-LD exposure compared to that in the no exposure group. New bone was observed around exposed specimens in the histological evaluation, and both the bone-to-specimen contact ratio and the new bone area increased significantly in exposed groups. Conclusions This study suggested that exposure of titanium to BV-LD can enhance the osteoconductivity of the titanium surface and induce antibacterial properties, similar to the properties observed following exposure to UV-LED.
Cultivable Anaerobic Microbiota of Infected Root Canals
Takuichi Sato,Keiko Yamaki,Naoko Ishida,Kazuhiro Hashimoto,Yasuhisa Takeuchi,Megumi Shoji,Emika Sato,Junko Matsuyama,Hidetoshi Shimauchi,Nobuhiro Takahashi
International Journal of Dentistry , 2012, DOI: 10.1155/2012/609689
Abstract: Objective. Periapical periodontitis is an infectious and inflammatory disease of the periapical tissues caused by oral bacteria invading the root canal. In the present study, profiling of the microbiota in infected root canals was performed using anaerobic culture and molecular biological techniques for bacterial identification. Methods. Informed consent was obtained from all subjects (age ranges, 34–71 years). Nine infected root canals with periapical lesions from 7 subjects were included. Samples from infected root canals were collected, followed by anaerobic culture on CDC blood agar plates. After 7 days, colony forming units (CFU) were counted and isolated bacteria were identified by 16S rRNA gene sequencing. Results. The mean bacterial count (CFU) in root canals was (0.5±1.1)×106 (range 8.0×101?3.1×106), and anaerobic bacteria were predominant (89.8%). The predominant isolates were Olsenella (25.4%), Mogibacterium (17.7%), Pseudoramibacter (17.7%), Propionibacterium (11.9%) and Parvimonas (5.9%). Conclusion. The combination of anaerobic culture and molecular biological techniques makes it possible to analyze rapidly the microbiota in infected root canals. The overwhelming majority of the isolates from infected root canals were found to be anaerobic bacteria, suggesting that the environment in root canals is anaerobic and therefore support the growth of anaerobes.
De Novo Synthesized Estradiol Protects against Methylmercury-Induced Neurotoxicity in Cultured Rat Hippocampal Slices
Takeshi Yamazaki, Megumi Yamamoto, Yasuhiro Ishihara, Shota Komatsu, Eiji Munetsuna, Masahiro Onizaki, Atsuhiko Ishida, Suguru Kawato, Takao Mukuda
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0055559
Abstract: Background Estrogen, a class of female sex steroids, is neuroprotective. Estrogen is synthesized in specific areas of the brain. There is a possibility that the de novo synthesized estrogen exerts protective effect in brain, although direct evidence for the neuroprotective function of brain-synthesized estrogen has not been clearly demonstrated. Methylmercury (MeHg) is a neurotoxin that induces neuronal degeneration in the central nervous system. The neurotoxicity of MeHg is region-specific, and the molecular mechanisms for the selective neurotoxicity are not well defined. In this study, the protective effect of de novo synthesized 17β-estradiol on MeHg-induced neurotoxicity in rat hippocampus was examined. Methodology/Principal Findings Neurotoxic effect of MeHg on hippocampal organotypic slice culture was quantified by propidium iodide fluorescence imaging. Twenty-four-hour treatment of the slices with MeHg caused cell death in a dose-dependent manner. The toxicity of MeHg was attenuated by pre-treatment with exogenously added estradiol. The slices de novo synthesized estradiol. The estradiol synthesis was not affected by treatment with 1 μM MeHg. The toxicity of MeHg was enhanced by inhibition of de novo estradiol synthesis, and the enhancement of toxicity was recovered by the addition of exogenous estradiol. The neuroprotective effect of estradiol was inhibited by an estrogen receptor (ER) antagonist, and mimicked by pre-treatment of the slices with agonists for ERα and ERβ, indicating the neuroprotective effect was mediated by ERs. Conclusions/Significance Hippocampus de novo synthesized estradiol protected hippocampal cells from MeHg-induced neurotoxicity via ERα- and ERβ-mediated pathways. The self-protective function of de novo synthesized estradiol might be one of the possible mechanisms for the selective sensitivity of the brain to MeHg toxicity.
Enormous Earthquake in Japan: Coping with Stress Using Purpose-in-Life/Ikigai  [PDF]
Riichiro Ishida
Psychology (PSYCH) , 2011, DOI: 10.4236/psych.2011.28118
Abstract: Every person has a will to achieve meaning and purpose in life (PIL)/ikigai. According to previous studies, PIL/ikigai provides people with the ability to integrate stressful psychological events from the past, present, and future with less conflict or confusion. This ability results in decreased anxiety and lower sympathetic nervous system activity during psychological and physical stressful situations. PIL/ikigai develops by positive experiences in one’s life such as experiencing sympathetic listening by others and being affected by persons and/or events. Overall, evidence shows that PIL/ikigai is an effective technique for coping with stress and helped many people cope with the enormous earthquake that occurred in Japan in March 2011.
Purpose in Life (Ikigai), a Frontal Lobe Function, Is a Natural  [PDF]
Riichiro Ishida
Psychology (PSYCH) , 2012, DOI: 10.4236/psych.2012.33038
Abstract: Stress can cause anxiety that creates imbalances in the autonomic nervous system and internal secretions leading to mental and somatic disease. Purpose in life (PIL) and ikigai (two social attitudes) help individuals to integrate psychological events and effectively cope with stress. PIL/ikigai provides an intrinsic motivation and is thought to develop primarily during adolescence. There is a correlation with such positive experiences as spending time in beautiful natural surroundings and exposure to warm human relationships at various developmental stages. PIL/ikigai is a physiological frontal lobe function. Adolescence is a critical period of development for PIL/ikigai and neuronal connections are strengthened by secretion of neurotransmitters such as dopamine and β-endorphin. We propose that there is an important physiologic role of PIL/ikigai and that critical periods of brain development influence development of PIL/ikigai.
Proposal to Prevent Alcohol Dependence Using Purpose in Life/Ikigai to Mimic the Chemical Effects of β-Endorphin  [PDF]
Riichiro Ishida
Psychology (PSYCH) , 2012, DOI: 10.4236/psych.2012.37078
Abstract: Purpose in life (PIL)/ikigai is a social attitude based on the concept that, “every person has a need to establish meaning in life”. Comfort and pleasure are related to the secretion of neurotransmitters such as serotonin, dopamine and β-endorphin. Drinking alcohol can also trigger emotions and cause the secretion of β-endorphin. Persons, who have an inner sense of satisfaction, do not need or want to induce comfort and pleasure by using alcohol or morphine. The primary chemical structures of β-endorphin and morphine are similar. Therefore, it is possible that helping people to achieve PIL/ikigai could strengthen psychological and/or physical defenses against alcohol dependence.
Association between Purpose in Life/(Ikigai), Prefrontal Cortex Function, and the Prevention of Halitosis Caused by Mental Stress, Pseudo-Halitosis, and Halitophobia  [PDF]
Riichiro Ishida
Psychology (PSYCH) , 2016, DOI: 10.4236/psych.2016.73029

Halitosis is a condition characterized by unpleasant oral odor or oral malodor problems that can lead to social and psychological impediments; it can be either genuine halitosis or pseudo-halitosis. One of the extra-oral conditions of genuine halitosis is mental stress, which causes a reduction in both saliva secretion and the presence of salivary lysing agents known as lysozymes, leading to oral malodor. Even in the absence of objective oral malodor, persons with pseudo-halitosis complain of halitosis symptoms, while those with halitophobia have a fear of halitosis. Genuine halitosis caused by stress, pseudo-halitosis, and halitophobia may all be due to anxiety resulting from an excessive need of approval from others. Purpose in life (PIL)/(ikigai), which is related to prefrontal cortex function, has been shown to be an effective way to manage stressful events, and is negatively correlated with an excessive need of approval from others. PIL/(ikigai), similar to prefrontal cortex function, develops through positive experiences from infancy to adolescence, such as spending time in beautiful natural surroundings, having success at meeting valued goals, and gaining empathetic acceptance and affection from others. Understanding the traits and developmental conditions associated with PIL/(ikigai) and prefrontal cortex function could improve the ability of individuals to manage stressful events, thereby promoting the prevention of halitosis, pseudo-halitosis, and halitophobia. The present proposal could contribute to future empirical research.

Sport Skill Evaluation with Wearable Sensors and Statistical Analysis  [PDF]
Kazunari Ishida
Open Journal of Social Sciences (JSS) , 2019, DOI: 10.4236/jss.2019.73019
This research discusses sport skill evaluation with wearable sensor and statistical analysis. Skateboarding is selected as the target sport to analyze because it will be an official competition in Tokyo 2020 Olympic Games. Skateboarding is one of the difficult sports because of controlling balance to move forward and to get speed on flat ground. The balance control is a basic trick named Tic-Tac, while the trick is difficult for beginners. To make data set for analyzing Tic-Tac skill, we have provided a basic lesson to research participants. After giving them enough self-training time, we put two inertial sensors on a skateboard and waist of a research participant and got total 41 running data with Tic-Tac. According to the result of statistical analysis on the data, we confirmed that swinging a skateboard left and right is the most important motion to generate moving forward driving forth. This result means that inertial sensors are one of the effective tools to evaluate sport skill for sports science and physical education.
Positive Maternal Attitudes during Infancy and a Positive Lifestyle May Be Associated with Beneficial Epigenetic Alterations and Improved Oral Health  [PDF]
Riichiro Ishida
Psychology (PSYCH) , 2019, DOI: 10.4236/psych.2019.105048
Abstract: Periodontitis causes various diseases, including arterial sclerosis, cardiac infarction, diabetes, aspiration pneumonia, and tooth loss, all of which lower the quality of life of individuals. Risk factors of periodontitis include a lack of oral care and low secretion of saliva due to stress, accompanied by excessive activity of the sympathetic nervous system and low secretion of serotonin and melatonin. Serotonin may improve the ability of individuals to manage stressful events, while melatonin may enhance the regeneration of tooth tissues. Saliva contains melatonin, epidermal growth factor, and nerve growth factor. The production and secretion of serotonin and melanin involve epigenetic mechanisms, i.e., gene expression resulting from chemical responses with genome sequences. Warm-hearted maternal attitudes to babies during infancy and a positive lifestyle, including a well-balanced diet, moderate aerobic exercise, and a purpose in life, as well as warm-hearted human relations, may also improve the ability of individuals to manage stressful events. This improvement in stress management may be linked to beneficial epigenetic alterations that promote the secretion of sufficient amounts of serotonin and melatonin, which may in turn contribute to the prevention and treatment of periodontitis and the regeneration of tooth tissues.
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