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Search Results: 1 - 10 of 2584 matches for " Giorgio Liguori "
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The Italian Society of Health Horizon Scanning (SIHHS)
Giorgio Liguori,Bruno Zamparelli
Italian Journal of Public Health , 2010, DOI: 10.2427/5736
Abstract: The Italian Society of Health Horizon Scanning (SIHHS) was created on May 4th, 2009, in Naples. The SIHHS’ main objective is to poll together and try to forecast the demand for technology products through the networking of professionals from regional healthcare units, universities and local Departments in Campania and Italy. Furthermore, the SIHHS intends to establish a set of clinical recommendations to be operatively used as strategic guidelines to enhance and promote their adoption within clinical and organizational settings. The general aim is to modernize the healthcare system through the design and/or the experimentation of innovative clinical, organizational and managerial models, efficaciously responding to healthcare needs, and contemporarily ensuring that the appropriate levels of benefits have been achieved, while minimizing risks and maximizing efficiency.
Epidemiology of HIV/AIDS: what has changed?
Giorgio Liguori,Francesca Gallé
Italian Journal of Public Health , 2005, DOI: 10.2427/5986
Abstract: The Authors examine the global, European and Italian epidemiology of HIV/AIDS on the basis of more recent international and national reports. All limitations in the available data were considered. The epidemic seems to have expand in all of the areas, demonstrating the need for further interventions both in the prevention of the infection and the diffusion of antiretroviral treatments, where these are lacking.
Epidemiology of hepatitis C virus infection in the world, Europe, Italy and Campania: an overview
Giorgio Liguori,Francesca Gallé,Paolo Marinelli
Italian Journal of Public Health , 2004, DOI: 10.2427/6141
Abstract: HCV infection is today the viral epidemic disease second only to AIDS. It is estimated that 3% of the world population is infected by hepatitis C and chronic related diseases, with markedly different prevalences between different geographical areas and different categories in the same area. The Authors analyse the epidemiological data available to trace the situation worldwide, in Europe, in Italy and in Campania, currently and in the last few years. Also researched was the role that the risk factors related to the different transmission routes play in the spread of the infection. Despite the decrease in the incidence reported in recent years, the numerous cases linked to drug abuse, to infections occurring while in health care and after unsafe sexual intercourse reveal the need for further information to be spread on HCV infection and on its modes of transmission.
Phenotypic and genotypic characterization of vancomycin-resistant enterococci in a university hospital of southern Italy
Giorgio Liguori,Paolo Villari,Stefania Boccia,Francesca Gallè
Italian Journal of Public Health , 2007, DOI: 10.2427/5880
Abstract: Background: In the last decades vancomycin-resistant enterococci (VRE) have emerged as important pathogens responsible for hospital-acquired infections. To analyze the spread and clonal relatedness of VRE, a two-year study of isolates was carried out in the hospital of the University “Federico II” in Naples. Methods: Enterococcus species were identified by using API-2 Strep and antibiotic susceptibility was determined through the use of four tests: disk diffusion, broth dilution methods, Etest and Vitek 2. Polymerase Chain Reaction (PCR) was used to analyse glycopeptide resistance. Pulsed-field gel electrophoresis (PFGE) and arbitrarily primed (AP)-polymerase chain reaction were used for molecular typing of the strains. Results: Thirty-two isolates of enterococci (18 E. faecium and 14 E. faecalis) showed resistance to vancomycin and teicoplanin and all the strains were vanA-positive. AP-PCR showed a unique clone of E. faecium, as well as for E. faecalis isolates. Identical results were obtained by PFGE for E. faecalis isolates, while three different PFGE patterns emerged for E. faecium. Conclusions: The low degree of genetic diversity among the isolates strongly suggests a clonal spread of antibiotic-resistant strains among hospitalized patients in high-risk wards. This report represents the first step to understanding VRE spread in our hospital as well as contributing to the comparison among different antibiotic susceptibility tests and molecular typing methods.
Opportunities for Prevenar 13 vaccine in Campania Region: a budget impact analysis
Giorgio Liguori,Antonino Parlato,Alessandro Scaletti,Patrizia Belfiore
Italian Journal of Public Health , 2012, DOI: 10.2427/5624
Abstract: : Background: although the efficacy of pneumococcal vaccination for the more common serotypes of Streptococcus pneumoniae has been demonstrated, the 13-valent vaccine (Prevenar 13 ) is still offered in different ways in the Italian regional healthcare units, and in the region of campania, some local health authorities administer the vaccine free of charge whilst others practice a co-payment. Methods: we performed a budget impact analysis of the possible free administration of Prevenar 13 vaccine to all newborns in the campania region, by comparing two different delivery settings, one having an active vaccination program and another in which such program was absent. during the operation of the vaccination program, the number of expected cases with 50, 80 and 100% vaccine coverage in the popula- tion was considered. the economic advantage resulting from pneumococcal diseases deemed avoidable thanks to the vaccination was compared with the costs of the vaccination program. the analysis considered the direct costs in the 2 years after implementation of the vaccination program. costs were expressed in € euros 2010. Results: although we did not consider the benefits achievable in the 10 years following the vaccina- tion, nor the herd effects, we showed that offering anti-pneumococcal vaccination to all newborns could give economic advantages to the region, estimated as close to 1 million euros. Conclusion: the use of Prevenar 13 can be considered a greatly advantageous public health strategy....
Health care services to diabetics in the territory of the Lha Napoli 2: quality perceived
Antonino Parlato,Daniela Ugliano,Aniello Visciano,Giorgio Liguori
Italian Journal of Public Health , 2007, DOI: 10.2427/5869
Abstract: Background: Worldwide, diabetes mellitus is a chronic disease which now appears to be substantially increasing especially in industrialized countries. In recent years important improvements have been achieved in the treatment of the disease and the prevention of complications, but adherence of health care workers to these indicators varies considerably and often the results are inadequate. Our study relates to health care services supplied to diabetics within the territory of LHA (Local Health Agency) Napoli 2 in Italian region of Campania. The results obtained from 3 district areas were then compared. Methods: The prevalence study was carried out by interviewing diabetes-affected patients (aged 18-64) in the territory examined. For each area, a representative number of patients was selected through simple casual sampling. Results: A minimal knowledge of risk factors associated with diabetes in respect to those registered at a national level, an incomplete adherence to recommended actions, a good perception of the quality of healthcare services and a good level of information were recorded from all of the 462 subjects interviewed. Conclusions: This study draws attention to the critical aspects in healthcare services supplied to diabetics. The data collected could be useful to more effective and efficient strategies of “disease management” resulting in the better allocation of resources.
Automated cleaning of fan coil units with a natural detergent-disinfectant product
Giorgio Liguori, Maria Bagattini, Francesca Gallè, Mario Negrone, Valeria Di Onofrio, Maria Triassi
Annals of Clinical Microbiology and Antimicrobials , 2010, DOI: 10.1186/1476-0711-9-29
Abstract: BATT2 has been utilized for the disinfection of fan coil units from four air conditioning systems located in hospital environments with a mean degree of risk. Samples were collected from the air supplied by the conditioning systems and from the surfaces of fan coil units, before and after sanitization procedures. Total microbial counts at 37°C and 22°C and mycotic count at 32°C were evaluated. Staphylococci and Pseudomonas aeruginosa were also detected on surfaces samples.The biodetergent was able to reduce up 50% of the microbial pollution of fan coil units surfaces and air supplied by the air conditioners.BATT2 could be considered for cleaning/disinfection of air conditioning systems, that should be performed on the basis of accurate and verifiable sanitization protocols.Microbial contamination of air has become of interest in the past two decades because of the correlation of sick building syndrome (SBS) with indoor air pollution [1,2]. In fact, the onset of SBS, which comprises a series of symptoms such as eye irritation, airways dryness, headache, sleepiness, and skin rash and itch, seems to be related to the presence of microbes or their components in indoor air [3-7]. Bio-contamination has the same harmful effects as chemical pollutants on the health of individuals [3]. This is important in hospital settings, especially for those units that accommodate patients with high-risk conditions [8].The main sources of microbial pollutants for indoor environments are people and air conditioning systems, which allow the survival and multiplication of microorganisms [9,10]. The dampness inside these systems, together with incorrect management of sanitization procedures, can promote the spread of microorganisms and cause transmission of many infectious diseases [4,7,9,10].In the past few years, the need to contain biological pollution in indoor environments has led to numerous strategies for the reduction of contamination of air conditioning systems, mainly in hospitals
Microbiological evaluation of the efficacy of two new biodetergents on multidrug-resistant nosocomial pathogens
Giorgio Liguori, Maria Bagattini, Francesca Gallè, Valeria Quartucci, Valeria Di Onofrio, Mario Negrone, Maria Triassi
Annals of Clinical Microbiology and Antimicrobials , 2009, DOI: 10.1186/1476-0711-8-35
Abstract: In-vitro antibacterial efficacy of BATT1 and BATT2 against nosocomial multidrug-resistant isolates was assessed using a suspension-inhibition test, with and without bovine serum albumin (BSA). The test was also carried out on glass surfaces with and without BSA.In vitro tests with both biocidal disinfectants at 25% concentration demonstrated an overall drop in bacterial, mould and yeast counts after 10 min of contact with or without organic substances. For Pseudomonas aeruginosa, it was necessary to use undiluted disinfectants with and without an organic substance. The same results were obtained in tests carried out on glass surfaces for all strains.The natural products BATT1 and BATT2 behave like good biocides even in presence of organic substances. The use of both disinfectants may be beneficial for reducing hospital-acquired pathogens that are not susceptible to disinfectants.However, it has to be stressed that all these experiments were carried out in vitro and they still require validation from use in clinical practice.At present, biocides are an integral component of clinical medicine, and serve to prevent the dissemination of nosocomial pathogens in the hospital environment [1]. In the last few years, despite remarkable progress in our knowledge of risk factors, prevention and control measures, the incidence of nosocomial infections has not decreased, and many outbreaks have been caused by new multidrug-resistant pathogens that have been selected by excessive and often irrational use of antibiotics [2,3]. These microorganisms are resistant to the majority of antibiotics and to many disinfectants, which has resulted in an increase in environmental contamination [4,5]. In many cases, it has been demonstrated that the molecular mechanisms responsible for antibiotic resistance are the same as those implicated in lack of susceptibility to biocides; anyway, some biocides have the ability to select for antibiotic resistant strains and vice versa [6-10]. Also, organi
Pattern of fractures across pediatric age groups: analysis of individual and lifestyle factors
Giuliana Valerio, Francesca Gallè, Caterina Mancusi, Valeria Di Onofrio, Marianna Colapietro, Pasquale Guida, Giorgio Liguori
BMC Public Health , 2010, DOI: 10.1186/1471-2458-10-656
Abstract: A cross-sectional study was performed in the first six months of 2008 through questionnaire on a sample of children from an outpatient clinic for pediatric fractures. Differences in gender, anatomic site, circumstances and location of fracture occurrence, behavioural lifestyle, and calcium intake were investigated among three different age classes (pre-school children, school children, and adolescents).The sample consisted of 382 subjects (2-14 years of age) sustaining a fracture after low or moderate trauma. Males were at a higher risk of fractures than females; greater than two-thirds of injuries occurred after low-energy trauma and the upper limb was more frequently involved. With increasing age, the male/female ratio and time spent in sports participation increased (p < 0.001), while calcium intake and time spent in sedentary behaviors decreased (p < 0.001 and < 0.003, respectively). Gender discordance existed in pre-school children with respect to the anatomic location, and in school children and adolescents with respect to the dynamics. In the adolescent group, males were more physically active and also more sedentary than females. Fractures most frequently occurred in homes (41.6%), followed by playgrounds and footpaths (26.2%), sports facilities (18.3%), and educational facilities (13.9%), with gender differences existing only in adolescence. Twenty-three percent of the subjects sustained one or more fractures in the past. The percentage of recurrent fractures increased with age (p = 0.001), with a similar trend in both genders.Gender differences were shown in the prevalence of injuries, characteristics, and circumstances across ages. These differences may be explained by the related changes in behaviors, together with attending different places. Individual and lifestyle factors can in part explain the variability in the occurrence of fractures and can also address targeted preventive strategies.Fractures are extremely common in the pediatric age group, repr
Microbiological quality of drinking water from dispensers in Italy
Giorgio Liguori, Ivan Cavallotti, Antonio Arnese, Ciro Amiranda, Daniela Anastasi, Italo F Angelillo
BMC Microbiology , 2010, DOI: 10.1186/1471-2180-10-19
Abstract: For each sample, microbial parameters and chemical indicators of contamination were evaluated and information about the date of installation, time since last ordinary and extraordinary maintenance of water coolers was collected.In all samples the chemical parameters (nitrite, ammonium, free active chlorine residual) did not exceed the reference values of the drinking water regulation; the pH value in 86.8% samples of the carbonated waters was lower than the reference limit. The microbiological results indicated that the bacteria count at 22°C and 37°C was higher than the required values in 71% and 81% for the non-carbonated water and in 86% and 88% for the carbonated one, respectively. Enterococcus spp. and Escherichia coli were not detected in any of the water samples. Pseudomonas aeruginosa was found in only one sample of the tap water and in 28.9% and 23.7% of the non-carbonated and carbonated water samples, respectively. No statistically significant differences in bacterial counts at 22°C and 37°C have been found between the non-carbonated and carbonated water from the sampled coolers in relation with the time since the last filter was substituted. The bacteriological quality of tap water was superior to that of non-carbonated and carbonated water from coolers.The results emphasize the importance of adopting appropriate routinely monitoring system in order to prevent or to diminish the chances of contamination of this water source.It is well known that the quality and safety of the drinking water continues to be an important public health issue [1,2], because its contamination has been frequently described as responsible for the transmission of infectious diseases that have caused serious illnesses and associated mortality worldwide [3-6]. Clearly, point-of-use water quality is a critical public health indicator [2].Over the past decade, there has been a markedly increase in the consumption of water derived from different sources in place of tap water for drinki
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