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Search Results: 1 - 10 of 461336 matches for " Ginette A. Mbourou "
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Sylvie Fortier,Fabien A. Basset,Ginette A. Mbourou,Jér?me Favérial
Journal of Sports Science and Medicine , 2005,
Abstract: The purpose of this study was twofold: (a) to examine if kinetic and kinematic parameters of the sprint start could differentiate elite from sub-elite sprinters and, (b) to investigate whether providing feedback (FB) about selected parameters could improve starting block performance of intermediate sprinters over a 6-week training period. Twelve male sprinters, assigned to an elite or a sub-elite group, participated in Experiment 1. Eight intermediate sprinters participated in Experiment 2. All athletes were required to perform three sprint starts at maximum intensity followed by a 10-m run. To detect differences between elite and sub-elite groups, comparisons were made using t-tests for independent samples. Parameters reaching a significant group difference were retained for the linear discriminant analysis (LDA). The LDA yielded four discriminative kinetic parameters. Feedback about these selected parameters was given to sprinters in Experiment 2. For this experiment, data acquisition was divided into three periods. The first six sessions were without specific FB, whereas the following six sessions were enriched by kinetic FB. Finally, athletes underwent a retention session (without FB) 4 weeks after the twelfth session. Even though differences were found in the time to front peak force, the time to rear peak force, and the front peak force in the retention session, the results of the present study showed that providing FB about selected kinetic parameters differentiating elite from sub-elite sprinters did not improve the starting block performance of intermediate sprinters
GP88 (Progranulin) Confers Fulvestrant (Faslodex, ICI 182,780) Resistance to Human Breast Cancer Cells  [PDF]
Wisit Tangkeangsirisin, Ginette Serrero
Advances in Breast Cancer Research (ABCR) , 2014, DOI: 10.4236/abcr.2014.33010

The 88 kDa glycoprotein known as GP88, Progranulin or PC cell derived growth factor is an autocrine growth factor with a unique cysteine rich motif that is over expressed in breast cancer whereas it is negative in normal mammary epithelial cells. It has been shown to play a major role in estrogen independence, tamoxifen resistance and tumorigenesis of breast cancer cells. In the present study, we investigated the effect of GP88 overexpression on the response of the human breast cancer MCF-7 cells to the pure estrogen receptor antagonist fulvestrant (ICI 182,780). While fulvestrant effectively inhibited cell proliferation of empty vector transfected cells, it had no inhibitory effect on the proliferation of GP88 overexpressing breast cancer cells. Mouse xenograft experiments in athymic ovariectomized nude mice showed that GP88 over expressing cells were fulvestrant resistant in vivo in contrast to low GP88 expressing cells. We show that the ability of fulvestrant to induce apoptosis determined by measuring cleavage of poly (ADP-ribose) polymerase was inhibited by GP88. Anti-apoptotic activity of GP88 was associated with sustained expression of bcl-2 and bcl-xL after fulvestrant treatment. In contrast, fulvestrant was still able to inhibit the ability of estrogen to stimulate ERE-luciferase reporter gene activity as well as vEGF expression in GP88 over expressing MCF-7 cells similarly to control MCF-7 cells. Collectively, our data suggest that GP88 prevents apoptosis induced by faslodex and contributes to antiestrogen resistance in human breast cancer.

Castro Yánez,Ginette; Sandoval Zú?iga,María Soledad;
Revista Latinoamericana de Psicología , 2009,
Abstract: the literature reports the existence of a series of events in language acquisition, corresponding to different stages, as children advance from basic to more complex grammar structures when learning their first language. with the greater complexity of the syntax context, children should produce phrases where prepositions appear. thus, the syntax context should be one of the prerequisites for the appearance of these grammatical elements in their speech. to verify this hypothesis, our study collected recorded samples of children's language use in familiar contexts and with familiar interlocutors. the sample consisted in 16 children aged 18 to 36 months; and the sample was divided in four groups corresponding to the subject's age group (18, 24, 30 and 36 months). the results indicate that prepositions appear in more complex contexts when the child has learned the basic grammar of his/her first language, which occurs between 18 and 24 months of age.
La aparición de las preposiciones en ni os hispanohablantes entre los 18 y los 36 meses de edad
Ginette Castro Yánez,María Soledad Sandoval Zú?iga
Revista Latinoamericana de Psicología , 2009,
Abstract: Con fundamento en la literatura que da cuenta de la existencia de una serie de hitos en la adquisición del lenguaje, correspondientes a las etapas en las que se observa que el ni o pasa de una gramática básica a una gramática más compleja en su lengua materna, se considera que el contexto sintáctico complejo exige que el ni o produzca enunciados en los que deben aparecer preposiciones. Así, el contexto constituye uno de los prerrequisitos para que ocurra la aparición de dichos elementos gramaticales en el habla. Para apoyar esta tesis, en este estudio se recogieron datos a partir de muestras grabadas de lenguaje infantil en un contexto y con un interlocutor familiares. La muestra la conformaron 16 ni os de 18 a 36 meses de edad y se dividió en cuatro grupos correspondientes a las edades de los sujetos (18, 24, 30 y 36 meses). El análisis de los resultados indica que las preposiciones aparecen en contextos más complejos cuando el ni o ha aprendido la gramática básica de su lengua materna, entre los 18 y 24 meses de vida.
El sue o de la letra.
Ginette Barrantes.
Affectio Societatis , 2002,
Abstract: El sue o de la letra devino título de mi exposición en referencia a un sue o propio- sue o que no abordaré aquí-, así como también a la pertenencia del sue o a la escritura. El sue o de la letra se convirtió asimismo, en la evocación de la intención freudiana de leer el sue o a partir de su relato, es decir, como una escritura en el habla. Tal como se afirma en "La interpretación de los sue os"(1) (Die Traumdeutung), la interpretación plateada como desciframiento misma cobra gran relevancia. Es, precisamente, mi deseo de indagar más sobre la operación de lectura que realiza el analista en la clínica, lo que me ha llevado a plasmar la relación entre "lectura" y "desciframiento del sue o", como uno de los temas centrales de mi presentación esta noche. Esta inquietud por la letra y la lectura pueden encontrarla en algunos de mis textos, en los cuales encuentro ahora muchas imprecisiones.
Secondary Bithalamic Ischemic Vascular Accident Has an Occlusion of the Artery of Percheron  [PDF]
Jennifer Nyangui Mapaga, Ibrahima A?ssata Camara, Grass Aurelle Mambila Matsalou, Pupchen Marilyse Gnigone, Nelly Diouf Mbourou, Annick Nsounda Mandzela, Cherif Mohamadou Aidara, Kouna Ndouongo Philomène
Open Access Library Journal (OALib Journal) , 2019, DOI: 10.4236/oalib.1105169
The bithalamic ischemic stroke secondary to percheron artery occlusion occupies a small place in the large ischemic stroke family, but its clinical polymorphism arouses patrician curiosity. We thus report 3 observations that explain the richness of this affection.
étude des conditions de mutagenèse de la souche bhk 21/13 pour la sélection de résistants a la 5-bromodeoxyuridine ou a la 8-azaguanine
M Caboche, Ginette Giffard
Genetics Selection Evolution , 1973, DOI: 10.1186/1297-9686-5-4-477
Developing global leaders through doctoral education
Rodger, Ginette Lemire;
Revista Latino-Americana de Enfermagem , 2004, DOI: 10.1590/S0104-11692004000500016
Abstract: nursing leadership has become a major theme of discussions in many countries. the phenomenon is also present in nursing as the profession is redesigning and reinventing itself in all domains of practice. this paper discusses the development of global nursing leaders through doctoral education in the context of 21st century realities. next, two meanings of global leadership of nursing are reviewed. finally, doctoral education is focused by looking at worldviews and the challenges ahead in preparing global nursing leaders for the 21st century.
Countering school bullying: An analysis of policy content in Ontario and Saskatchewan
Ginette Diane Roberge
International Journal of Education Policy and Leadership , 2011,
Abstract: The incidence of extreme school violence as a direct consequence of bullying among peers, exacerbated by vast media attention, has caused educational institutions worldwide to put bullying intervention and prevention strategies into operation. This study focused on an overview of two provincewide antibullying incentives in the Canadian provinces of Ontario and Saskatchewan, and an analysis of the quality of their respective antibullying policies. An itemized list of beneficial practices for bullying intervention and prevention originated from Smith, Smith, Osborn and Samara (2008)’s scoring scheme. The scoring scheme was adapted to the current study by linking research-based program elements that have been found to be effective in reducing school bullying to a content analysis of both provincial frameworks. The final scoring scheme comprised a total of 39 criterions, divided into five categories: Defining Bullying Behaviors, Establishing a Positive School Climate, Disseminating, Monitoring and Reviewing Policy, Reporting and Responding to Bullying, and Involving the Broader Community. Results showed that policies contained a total average of 60% of the criterions in Ontario, and 59% in Saskatchewan. The conclusion of this study observes from policy lenses key essentials of bullying intervention and prevention initiatives in elementary and secondary educational settings. Recommendations are proposed to bridge the gap between areas that have received extensive attention and areas that have received less treatment in bullying intervention and prevention endeavors, using the content of Ontario and Saskatchewan policies as a basis for discussion.
Post-Stroke Depression at Teaching Hospital Center of Libreville  [PDF]
I. A. Camara, C. M. Coulibaly, N. Diouf Mbourou, P. M. Gnigone, G. A. G. Mambila Matsalou, A. Nsounda Mandzela, L. Oura, J. Nyangui Mapaga, U. D. Kombila, M. M. Moubecka, P. N. Kouna
Open Access Library Journal (OALib Journal) , 2018, DOI: 10.4236/oalib.1105049
Introduction: Post-stroke depression occurs in a context of stroke characterized by sadness, loss of interest, feelings of guilt, loss of appetite, a feeling of tiredness, and a lack of concentration. Material and Methods: We conducted a descriptive cross-sectional study from January 1, 2013 to September 30, 2016. For the diagnosis of post-stroke depression, neuropsychological tests (DSM-IV and MADRS) were used. The collection approach was a maintenance survey followed by an examination. Results: From 153 stroke patients, 48.4% (n = 74) had post-stroke depression. Depressed mood was noted in 50.3% and 43.8% had a marked decrease in interest. 67.9% of these patients had a primary level of education. Widows had 4.2 times the risk of post-stroke depression, and married and retired patients were 3 times more likely than public servants. The occurrence of post-stroke depression was significantly related to the presence of motor deficit in our patients, p < 0.0001. Conclusion: These results suggest that the risk of developing depression after stroke increases with the motor deficit. The DSM-IV and MADRS scores remain neuropsychological examinations of choice for the diagnostic approach.
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