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Search Results: 1 - 10 of 192258 matches for " Gilda; Sardi?as Díaz "
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Bases genéticas del síndrome de ovarios poliquísticos
Ovies Carballo,Gisel; Martínez de Sandelices,Alicia; Monteagudo Pe?a,Gilda; Sardi?as Díaz,Irelys;
Revista Cubana de Endocrinolog?-a , 2011,
Abstract: the syndrome of polycystic ovaries is the endocrine disorder involving more the reproductive sphere of the woman in fertile age, its causes are unknown with accuracy, but most of experts coincide in propose that it is a multifactor entity where the genetic factor more and more have a great significance. in past years, it has been possible to identify some genes involved in the pathogenic processes of this syndrome and among the more important are included those codifying for enzymes of the steroidogenesis, for the insulin receptor and other hormones related to the insulin action, as well as the gonadotropins and its receptors, features that are the aim of present review.
Bases genéticas del síndrome de ovarios poliquísticos Genetic bases of polycystic ovary syndrome
Gisel Ovies Carballo,Alicia Martínez de Sandelices,Gilda Monteagudo Pe?a,Irelys Sardi?as Díaz
Revista Cubana de Endocrinología , 2011,
Abstract: El síndrome de ovarios poliquísticos es el trastorno endocrino que más afecta la esfera reproductiva de la mujer en la edad fértil, sus causas se desconocen con exactitud, pero la mayoría de los expertos coinciden en plantear que es una entidad multifactorial, en la que los factores genéticos cada vez cobran mayor importancia. En los últimos a os se han identificado varios genes involucrados en los procesos patogénicos de este síndrome, y dentro de estos, los más importantes son aquellos que codifican para enzimas de la esteroidogénesis, para el receptor de insulina y otras hormonas relacionadas con la acción de la insulina, así como las gonadotropinas y sus receptores, aspectos sobre los cuales trata la siguiente revisión. The syndrome of polycystic ovaries is the endocrine disorder involving more the reproductive sphere of the woman in fertile age, its causes are unknown with accuracy, but most of experts coincide in propose that it is a multifactor entity where the genetic factor more and more have a great significance. In past years, it has been possible to identify some genes involved in the pathogenic processes of this syndrome and among the more important are included those codifying for enzymes of the steroidogenesis, for the insulin receptor and other hormones related to the insulin action, as well as the gonadotropins and its receptors, features that are the aim of present review.
Evaluation of BacT/ALERT 3D System for Mycobacteria Isolates  [PDF]
María Rosarys Martinez, Misleidis Sardi?as, Grechen Garcia, Lilian M. Mederos, Raúl Díaz
Journal of Tuberculosis Research (JTR) , 2014, DOI: 10.4236/jtr.2014.22007
Abstract: Background: The rapid diagnosis of mycobacterial infections is essential to implement the adequate antimicrobial therapy. This study evaluates the performance of the BacT/ALERT 3D system for isolates and identification of mycobacteria from clinical samples. Methods: 1011 clinical specimens from nonsterile and sterile body sites were studied from August 2010 to December 2012 at the National Reference Laboratory of Tuberculosis, IPK, Cuba. The results obtained were compared with respect to time detection of mycobacteria and contamination rates, and performance indicators of BacT/ALERT 3D were calculated. Results: The time detection of growth (TDG) for Mycobacterium tuberculosis (Mtb) and nontuberculous mycobacteria (NTM) by BacT/ALERT 3D was 16,435 and 10,956, respectively; by LJ the TDG was 33.577 for Mtb and 35.952 for NTM. By culture method used the TDG for LJ was 33,577 and 6.435 by BacT/ALERT 3D, this difference being statistically significant. The overall contamination rate (CR) for BacT/ALERT 3D was 4.6% and 7.8% for LJ. Conclusions: BacT/ALERT 3D were a suitable method for recovering mycobacteria from clinical samples. It demonstrated a shorter time to detection of mycobacteria growth; it was very useful to provide faster treatment and a better prognosis in patients AFB smear negative with HIV. The use of LJ culture and BacT/ALERT 3D System was useful to assure a total mycobacterial recovery.
Estados clínicos y autopercepción de la sexualidad en ancianos con enfoque de género
Martín Hernández,Magny; Renteria Díaz,Pedro; Sardi?as Llerenas,Evaldo;
Revista Cubana de Enfermer?-a , 2009,
Abstract: we live in an aging society. by tradition, society has feed a series of myths, taboos, and negative stereotypes on sexuality in third age, difficulting a serious study of this matter. we made a descriptive study to determine relationship between clinical stage and self-perception of sexuality in gerontics with a gender vision. sample included 40 patients located into two groups, one of study including 20 patients admitted in "dr. celestino hernández" geriatric hospital and other of controls including 20 patients of grandparent circle of 75-1 family physicians consulting room of "ramón pando" polyclinic of santa clara municipality with a review of geriatric history, applying a sexuality questionnaire, self-esteem and self-evaluation inventory. information retrieved was analyzed in a quantitative way. interestingly, surveyed persons from parents circle had more cardiovascular diseases influencing in a great percentage in self-perception of sexuality. self-esteem and self-evaluation were directly related each other, and self-perception of sexuality. there were differences related directly to coincidence of these three levels, greater in control group. we concluded that active sexuality of both groups has repercussion on wellbeing, mental health, and quality of life.
Estados clínicos y autopercepción de la sexualidad en ancianos con enfoque de género Clinical stages and sexuality self-perception in elderlies: genre approach
Magny Martín Hernández,Pedro Renteria Díaz,Evaldo Sardi?as Llerenas
Revista Cubana de Enfermer?-a , 2009,
Abstract: Vivimos en una sociedad envejecida. Tradicionalmente la sociedad ha alimentado una serie de mitos, tabúes y estereotipos negativos acerca de la sexualidad en la vejez que ha hecho muy difícil un estudio serio sobre este tema. Se realizó un estudio descriptivo con el objetivo de determinar la relación entre el estado clínico y la autopercepción de la sexualidad en gerontes con visión de género. La muestra quedó conformada por 40 pacientes distribuidos en 2 grupos, uno de estudio integrado por 20 pacientes ingresados en el servicio de geriatría del Hospital Dr. Celestino Hernández y otro testigo conformada por 20 pacientes del círculo de abuelos del Consultorio Médico de la Familia 75-1 del policlínico Ramón Pando del municipio Santa Clara, a los que se le realizó revisión de la Historia Geriátrica, se les aplicó un cuestionario de sexualidad, el inventario de autoestima y de autovaloración. La información recogida se analizó cuanticualitativa. Resultó significativo que los encuestados pertenecientes al círculo de abuelos presentaban mayor diversidad de enfermedades con menor repercusión en su sexualidad, siendo en ambos grupos las enfermedades cardiovasculares las que influyen en mayor porciento en la autopercepción de la sexualidad. La autoestima y la autovaloración guardaron relación directa entre ellas y la autopercepción de la sexualidad, existieron diferencias en el porciento de coincidencia de estos tres niveles, que fue mayor en el grupo testigo y se llegó a la conclusión que la sexualidad activa de ambos grupos repercute en su bienestar, su salud mental y su calidad de vida. We live in an aging society. By tradition, society has feed a series of myths, taboos, and negative stereotypes on sexuality in third age, difficulting a serious study of this matter. We made a descriptive study to determine relationship between clinical stage and self-perception of sexuality in gerontics with a gender vision. Sample included 40 patients located into two groups, one of study including 20 patients admitted in "Dr. Celestino Hernández" Geriatric Hospital and other of controls including 20 patients of Grandparent Circle of 75-1 Family Physicians Consulting Room of "Ramón Pando" Polyclinic of Santa Clara municipality with a review of Geriatric History, applying a sexuality questionnaire, self-esteem and self-evaluation inventory. Information retrieved was analyzed in a quantitative way. Interestingly, surveyed persons from Parents Circle had more cardiovascular diseases influencing in a great percentage in self-perception of sexuality. Self-esteem and self-evalua
Comparative mapping reveals quantitative trait loci that affect spawning time in coho salmon (Oncorhynchus kisutch)
Araneda, Cristian;Díaz, Nelson F.;Gomez, Gilda;López, María Eugenia;Iturra, Patricia;
Genetics and Molecular Biology , 2012, DOI: 10.1590/S1415-47572012000300019
Abstract: spawning time in salmonids is a sex-limited quantitative trait that can be modified by selection. in rainbow trout (oncorhynchus mykiss), various quantitative trait loci (qtl) that affect the expression of this trait have been discovered. in this study, we describe four microsatellite loci associated with two possible spawning time qtl regions in coho salmon (oncorhynchus kisutch). the four loci were identified in females from two populations (early and late spawners) produced by divergent selection from the same base population. three of the loci (omyfgt34tuf, one2asc and one19asc) that were strongly associated with spawning time in coho salmon (p < 0.0002) were previously associated with qtl for the same trait in rainbow trout; a fourth loci (oki10) with a suggestive association (p = 0.00035) mapped 10 cm from locus omyfgt34tuf in rainbow trout. the changes in allelic frequency observed after three generations of selection were greater than expected because of genetic drift. this work shows that comparing information from closely-related species is a valid strategy for identifying qtls for marker-assisted selection in species whose genomes are poorly characterized or lack a saturated genetic map.
Neoplasias malignas: caracterización
Hernández Cisneros,Freddie; Díaz Segui,Damarys; Sardi?as Montes de Oca,Odalys; Martínez Cabrera,Norma;
Revista Cubana de Medicina General Integral , 1997,
Abstract: : a cross-sectional study was carried out, with the aim of characterizing the patients with malignant neoplasms in a health area, from march 1994 to august of the same year; the universe of study was represented by 75 patients diagnosed with some kind of malignant disease, and the primary score of the data, by means of a survey with selected variables; information was processed in a computed way. the most important results found, were: the highest incidence in the 50 years old or more age group; the 56 % smoked, and the 17.33 % drank alcoholic beverages; the three most frequent sites, were: breast, cervix uteri and skin, and also outstanding defficiencies were detected in the promotion and prevention of these diseases.
Displasia septo-óptica o síndrome DeMorsier: Presentación de 1 caso y revisión bibliográfica
José Vargas Díaz,Norberto Sardi?as Hernández,Elia M. Pestana Knight,Gabriel Rodríguez García
Revista Cubana de Pediatr?-a , 2000,
Abstract: La displasia septo-óptica (DSO) o síndrome DeMorsier es un cuadro congénito de presentación poco frecuente, constituido por hipoplasia de 1 o más frecuentemente, de ambos nervios ópticos, ausencia de septum pellucidum y deficiencias hormonales. Se presenta una lactante de 6 meses de edad que es atendida porque la ni a no mostraba interés visual y no sostenía la cabeza. Durante el embarazo su mamá tenía bajo peso corporal y padeció de infección urinaria en el último trimestre del embarazo. Durante los 2 primeros meses de vida presentó fiebre de hasta 38 ° C sin que se pudiera identificar un proceso infeccioso como causante. En su examen neurológico se halló hipotonia generalizada de predominio axial con reflejos osteotendinosos presentes, nistagmus horizontal, estrabismo convergente, ausencia de reflejo visuopalpebral y en el fondo de ojo bilateralmente papilas muy peque as con imagen de doble contorno. El ultrasonido cerebral y la tomografía axial computadorizada (TAC) mostraron ausencia del septum pellucidum. La edad ósea se correspondió con 4 meses y se encontró deficiencia de la hormona del crecimiento con valores de 4 ng/L. Las manifestaciones clínicas de esta paciente se corresponden con la triada clásica del síndrome DeMorsier; hipoplasia del nervio óptico, agenesia del septum pellucidum y deficiencias hormonales, en este caso de hormona del crecimiento. Se presenta una actualización de esta enfermedad poco frecuente. The septo-optic dysplasia or DeMorsier's syndrome is a rare congenital disease consisting in hypoplasia of one or more frequently of both optic nerves, absence of septum pellucidum and hormone deficiencies. Clinical case: A female infant of 6 months of age receives attention because the girl had no visual interest and was not able to hold up her head. Her mother had low body weight and suffered from urinary infection in the last trimester of pregnancy. During the first 2 months of life she had fever of up to 38oC and it was not possible to identify any infectious process as its cause. Generalized hypotonia of axial predominance with osteotendinous reflexes, horizontal nystagmus, convergent strabismus, absence of visuopalpebral reflex and, bilaterally, in the fundus of the eye small papillae with double contour image. The cerebral ultrasound and the computerized axial tomography (CAT) showed absence of the septum pellucidum. The osteal age corresponded with 4 months and it was found a deficiency of the growth hormone with values of 4 ng/L. The clinical manifestations of this patient matched with the classic triad of DeMorsier's syndro
Evaluación del control de calidad de la baciloscopia en el diagnóstico de la tuberculosis en Cuba Evaluation of quality control of baciloscopy in tuberculosis diagnosis in Cuba
María Rosarys Martínez Romero,Misleidis Sardi?a Aragón,Grechen García,Marisol Díaz Almaguer
Revista Cubana de Medicina Tropical , 2006,
Abstract: Se evaluó el diagnóstico de tuberculosis en los laboratorios de los Centros Provinciales de Higiene y Epidemiología de Cuba incluido el municipio especial Isla de la Juventud. Se realizó el control de calidad a 4 382 láminas en el período enero-diciembre de 2004, según lo establecido en el Manual de Procedimientos del Programa Nacional de Control de Tuberculosis. Mostraron buena calidad en la extensión y coloración de Zielh Neelsen 4 003 (91,35 %) láminas. El coeficiente de concordancia global del Laboratorio Nacional de Referencia de Tuberculosis en relación con los laboratorios provinciales fue de 99,79 %. La sensibilidad y especificidad presentaron valores superiores a 99 %. Estos resultados sugieren la calidad del diagnóstico de la baciloscopia de tuberculosis en los laboratorios provinciales y se alan la necesidad de no descuidar las continuas supervisiones, el monitoreo y el reentrenamiento en la técnica de baciloscopia, que sientan las bases para la introducción de los métodos de rechequeo a ciegas y panel de láminas dirigidas a perfeccionar la calidad del diagnóstico de tuberculosis en Cuba. This study was aimed at evaluating the diagnosis of tuberculosis in Provincial Hygiene and Epidemiological Centers of the country including special municipality Isle of Youth. The quality control was performed on 4 382 sputum smears from January to December 2004 following the Manual of Procedures of the National Tuberculosis Control program. Good quality in Zielh Neelsen extension and staining was seen in 4 003 smears (91.35%). The overall agreement coefficient between the National Tuberculosis Reference Laboratory and the rest of the provincial laboratories was 99.79%. Sensitivity and specificity figures were over 99%. These results showed the quality of sputum smears microscopy diagnosis at provincial laboratories and the need of carrying out permanent supervision, monitoring and re-training of staff in acid-fast bacilli test in order to lay down the foundations for the introduction of blind rechecking methods and panel of sputum smears, aimed at improving the tuberculosis diagnosis quality in Cuba.
Introducción de nuevos métodos de control de calidad de baciloscopia de esputo BAAR, en el Laboratorio Nacional de Referencia del Instituto de Medicina Tropical "Pedro Kourí" Introduction of new sputum bacilloscopy quality control methods in the National Reference Laboratory of "Pedro Kourí" Institute
María Rosarys Martínez Romero,Gretchen García León,Misleidis Sardi?a Aragón,Marisol Díaz Almaguer
Revista Cubana de Medicina Tropical , 2007,
Abstract:
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