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Search Results: 1 - 10 of 198870 matches for " Gilda; Padrón Durán "
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Evaluación de las alteraciones lipídicas en el síndrome de ovarios poliquísticos y su relación con la resistencia a la insulina
García García,Yudit; Monteagudo Pe?a,Gilda; Padrón Durán,Rubén S.; González Suárez,Roberto;
Revista Cubana de Endocrinolog?-a , 2010,
Abstract: introduction: the polycystic ovaries syndrome to exceed the reproductive axis due to its frequent association with metabolic and cardiovascular alterations. objective: based on above mentioned a cross-sectional and descriptive study was conducted to determine the frequency and the characteristic of lipid alterations en a group of women diagnosed with polycystic ovaries and its relation to alterations in insulin-sensitivity. methods: twenty three women were studied according to androgen excess society criteria, hormonal and lipid determinations were made as well as fasting glycemia and insulinemia to assess the insulin-sensitivity. results: the 95,6% of patients presenting with dyslipemia. the more frequent lipid alterations were a decrease of the high density lipoproteins (chdl) and apolipoproteins (apo) (91,3 and 87,0 %, respectively) whereas the increase of triglycerides(tg) and the total cholesterol (tc) were infrequent (13 and 4,3 %, respectively). the estimated lipid rates: tg/chdl, ct/chdl, chdl/cldl and apo b/a-i had higher mean values in women with insulin-resistance; the apo b/a-i rate had the greater difference in women with insulin-resistance and without it. conclusion: the lipid alterations frequency in study women suggest that in expression of polycystic ovaries syndrome could be involved many metabolic and hormonal factors.
Evaluación de la sensibilidad a la insulina en el síndrome de ovarios poliquísticos
García García,Yudit; Monteagudo Pe?a,Gilda; Padrón Durán,Rubén S.; González Suárez,Roberto;
Revista Cubana de Endocrinolog?-a , 2009,
Abstract: introduction: women with polycistic ovary syndrome have a increasing risk of insulin resistance, dyslipidemia, obesity, hypertension and type 2 diabetes mellitus; thus, with higher likelihood to develop cardiovascular disease. objective: to determine the frequency and features of insulin sensitivity disorders in a group of women with polycistic ovary syndrome. methods: twenty three women with this diagnosis were studied according to the androgen excess society (aes) criteria,underwent basal glycemia and insulinemia determinations and during frequently sampled intravenous glucose tolerance test). several insulin sensitivity and insulin resistance mathematic indexes were calculated. results: sixty-five percent of women had insulin resistance (homa-ir 3 3.22 rate). analysis of area under the curve of insulin during the test revealed that women with insulin resistance had higher insulinemia rates in baseline state and post-stimulation;in both groups concentrations were similar to the initial ones at the end of test. glycemia and insulinemia 0-10 areas and insulin area were higher in women with insulin resistance. all indexes including io/go, firi, isi, belfiore, bennet and quicki had a good correlation with homa-ir. conclusions: insulin resistance and hyperinsulinism frequency in women with policystic ovary syndrome was high and the fasting insulin resistance assessment may to predict the response during the glucose-intravenous stimulation.
Evaluación de la sensibilidad a la insulina en el síndrome de ovarios poliquísticos Evaluation of insulin-sensitivity in polycistic ovary syndrome
Yudit García García,Gilda Monteagudo Pe?a,Rubén S. Padrón Durán,Roberto González Suárez
Revista Cubana de Endocrinología , 2009,
Abstract: INTRODUCCIóN: las mujeres con síndrome de ovarios poliquísticos tienen un aumento del riesgo de padecer resistencia a la insulina, dislipidemia, obesidad, hipertensión arterial y diabetes mellitus tipo 2; por lo tanto, tienen mayor probabilidad de desarrollar enfermedad cardiovascular. OBJETIVO: determinar la frecuencia y características de los trastornos de la sensibilidad a la insulina en un grupo de mujeres con síndrome de ovarios poliquísticos. MéTODOS: se estudiaron 23 mujeres con este diagnóstico según los criterios de la Androgen Excess Society (AES), a las cuales se les realizaron determinaciones de glucemias e insulinemias basales y durante la prueba de tolerancia a la glucosa endovenosa de muestras múltiples. Se calcularon varios índices matemáticos de sensibilidad a la insulina e insulinorresistencia. RESULTADOS: 65 % de las mujeres tenían insulinorresistencia (índice HOMA-IR 3 3,22). El análisis del área bajo la curva de insulinemia durante la prueba evidenció que las mujeres con insulinorresistencia tenían insulinemias mayores en estado basal y posestimulación; en ambos grupos las concentraciones fueron similares a las iniciales al final de la prueba. El área glucémica e insulinémica 0-10 y el área total de la insulinemia fueron significativamente mayores en las mujeres con insulinorresistencia. Todos los índices I0/G0, FIRI, ISI, Belfiore, BENNET y QUICKI tuvieron buena correlación con el HOMA-IR. CONCLUSIONES: la frecuencia de insulinorresistencia e hiperinsulinismo en las mujeres con síndrome de ovarios poliquísticos estudiadas fue alta y las estimaciones de insulinorresistencia en estado de ayuno pueden predecir la respuesta durante la estimulación endovenosa con glucosa. INTRODUCTION: women with polycistic ovary syndrome have a increasing risk of insulin resistance, dyslipidemia, obesity, hypertension and type 2 diabetes mellitus; thus, with higher likelihood to develop cardiovascular disease. OBJECTIVE: to determine the frequency and features of insulin sensitivity disorders in a group of women with polycistic ovary syndrome. METHODS: twenty three women with this diagnosis were studied according to the Androgen Excess Society (AES) criteria,underwent basal glycemia and insulinemia determinations and during frequently sampled intravenous glucose tolerancetest). Several insulin sensitivity and insulin resistance mathematic indexes were calculated. RESULTS: sixty-five percent of women had insulin resistance (HOMA-IR 3 3.22 rate). Analysis of area under the curve of insulin during the test revealed that women with insulin resistance had h
Evaluación de las alteraciones lipídicas en el síndrome de ovarios poliquísticos y su relación con la resistencia a la insulina Assessment of the lipid alterations in polycystic ovaries syndrome and its relation to insulin-resistance
Yudit García García,Gilda Monteagudo Pe?a,Rubén S. Padrón Durán,Roberto González Suárez
Revista Cubana de Endocrinología , 2010,
Abstract: INTRODUCCIóN: el síndrome de ovarios poliquísticos excede el eje reproductivo por su frecuente asociación con alteraciones metabólicas y cardiovasculares. OBJETIVO: basado en lo anterior se realizó un estudio descriptivo transversal para determinar la frecuencia y las características de las alteraciones lipídicas en un grupo de mujeres con síndrome de ovarios poliquísticos y su relación con las alteraciones en la sensibilidad a la insulina. MéTODOS: se estudiaron 23 mujeres según los criterios de la Androgen Excess Society, se realizaron determinaciones hormonales y lipídicas así como glucemia e insulinemia en ayunas para evaluar sensibilidad a la insulina. RESULTADOS: 95,6 % de las pacientes presentaron dislipidemia. La disminución de las lipoproteínas de alta densidad (cHDL) y apolipoproteínas (Apo) A-I fueron las alteraciones lipídicas más frecuentes (91,3 y 87,0 %, respectivamente) mientras que el aumento de los triglicéridos (Tg) y del colesterol total (Ct) fueron infrecuentes (13 y 4,3 %, respectivamente). Los índices lipídicos calculados: Tg/cHDL, Ct/cHDL, cHDL/cLDL y Apo B/A-I tuvieron valores medios superiores en las mujeres con insulinorresistencia, el índice Apo B/A-I fue el que mostró mayor diferencia en mujeres con insulinorresistencia y sin esta. CONCLUSIóN: la frecuencia de las alteraciones lipídicas en las mujeres estudiadas fue alta pero no todas se relacionan con la insulinorresistencia, lo cual sugiere que en la expresión del síndrome de ovarios poliquísticos podrían intervenir múltiples factores metabólicos y hormonales. INTRODUCTION: the polycystic ovaries syndrome to exceed the reproductive axis due to its frequent association with metabolic and cardiovascular alterations. OBJECTIVE: based on above mentioned a cross-sectional and descriptive study was conducted to determine the frequency and the characteristic of lipid alterations en a group of women diagnosed with polycystic ovaries and its relation to alterations in insulin-sensitivity. METHODS: twenty three women were studied according to Androgen Excess Society criteria, hormonal and lipid determinations were made as well as fasting glycemia and insulinemia to assess the insulin-sensitivity. RESULTS: the 95,6% of patients presenting with dyslipemia. The more frequent lipid alterations were a decrease of the high density lipoproteins (cHDL) and apolipoproteins (Apo) (91,3 and 87,0 %, respectively) whereas the increase of triglycerides(Tg) and the total cholesterol (tC) were infrequent (13 and 4,3 %, respectively). The estimated lipid rates: Tg/cHDL, Ct/cHDL, cHDL/cLDL and Apo B/
Osteoporosis: un problema de salud en aumento Osteoporosis: a rising health problem
Rubén S Padrón Durán
Revista Cubana de Endocrinología , 2001,
Abstract:
Morbilidad en la consulta de endocrinología del Centro de Investigaciones Medicoquirúrgicas de Angola
Padrón Durán,Rubén S.; Guillén Pérez,Mayda;
Revista Cubana de Endocrinolog?-a , 2006,
Abstract: the data on morbidity at the outpatient department may be useful to know the causes for which the patients visit the health center, as well as to plan and provide special consultations and complementary tests. the objective of this study is to present and analyze morbidity at the endocrinology outpatient department of the center for medicosurgical research in angola. all the diagnoses of every case were collected for 28 months in a row. the specific diagnoses were classified into 7 big groups. 1) glycemia alterations, 2) obesity and other metabolic disorders, 3) reproductive medicine, 4) thryoid disorders, 5) pediatric endocrinology, 6) other endocrinopathies and 7) no endocrinopathies. 2 294 patients received medical attention. the most frequent diagnostic groups were type 2 diabetes mellitus (dm2) and exogenous obesity (53.01 and 24.72, respectively), followed by hyperlipoproteinemias (11.73). in a range between 4.5 and 10 %, we observed euthyroid diffuse goiter, altered fasting glycemia, female infertility and hyperuricemia. the rest was found in less than 3 % of the total of cases. the most important results and conclusions were the following: a) the most common diagnostic groups were glycemia alterations, obesity and other metabolic disorders, among them dm2 and exogenous obesity, b) the diagnoses of reproductive medicine and thyroid disorders were relatively frequent, c) the endocrine disorders at pediatric ages and other endocrinopathies were rare, d) the common endocrinometabolic disorders in other populations were unfrequent or non-existent reasons to seek medical attention, e) the results showed that the whole endocrinology care profile is not well known in this setting.
Morbilidad en la consulta de endocrinología del Centro de Investigaciones Medicoquirúrgicas de Angola Morbidity at the Endocrinology outpatient department of the Center for Medicosurgical Research in Angola
Rubén S. Padrón Durán,Mayda Guillén Pérez
Revista Cubana de Endocrinología , 2006,
Abstract: Los datos de la morbilidad en consulta externa pueden ser útiles para conocer las causas por las que los pacientes acuden al centro de salud, así como para planificar el ofrecimiento de consultas especiales y de exámenes complementarios. El objetivo de este estudio es presentar y analizar la morbilidad en la consulta externa de endocrinología del Centro de Investigaciones Medicoquirúrgicas de Angola (CIMECA). Se compilaron todos los diagnósticos de cada caso durante 28 meses consecutivos. Los diagnósticos específicos se clasificaron en 7 grandes grupos: 1) alteraciones de la glucemia, 2) obesidad y otros trastornos metabólicos, 3) medicina reproductiva, 4) trastornos del tiroides, 5) endocrinología pediátrica, 6) otras endocrinopatías y 7) sin endocrinopatías. Se atendieron 2 294 pacientes. Los grupos diagnósticos más frecuentes fueron: alteración de la glucemia (60,07) y obesidad y otros trastornos metabólicos (42,07); relativamente frecuentes fueron medicina reproductiva (19,4) y trastornos del tiroides (11,07). Sin embargo, los pacientes de endocrinología pediátrica (1,53) y otras endocrinopatías (0,22) fueron muy poco numerosos. Los diagnósticos específicos más comunes fueron la diabetes mellitus tipo 2 (DM2) y la obesidad exógena (53,01 y 24,72 respectivamente), seguidos por las hiperlipoproteinemias (11,73). En un rango entre 4,5 y 10 % observamos bocio difuso eutiroideo, glucemia en ayunas alterada, infertilidad femenina e hiperuricemia; el resto se halló en menos del 3 % del total de casos. Lo resultados y conclusiones más importantes del estudio son: a) Los grupos diagnósticos más comunes fueron las alteraciones de la glucemia y la obesidad y otros trastornos metabólicos, entre ellos la DM2 y la obesidad exógena, b) Los diagnósticos de medicina reproductiva y trastornos del tiroides fueron relativamente comunes, c) Los trastornos endocrinos en edades pediátricas y otras endocrinopatías fueron muy poco frecuentes, d) trastornos endocrinometabólicos comunes en otras poblaciones fueron motivo de consulta poco frecuentes o inexistentes, e) los resultados indican que en este medio no se conoce bien todo el perfil de atención de la endocrinología. The data on morbidity at the outpatient department may be useful to know the causes for which the patients visit the health center, as well as to plan and provide special consultations and complementary tests. The objective of this study is to present and analyze morbidity at the Endocrinology outpatient department of the Center for Medicosurgical Research in Angola. All the diagnoses of every case were coll
Reserva endocrina ovárica en mujeres con falla ovárica prematura
Padrón Durán,Rubén S.; Montejo Gómez,Lidermys;
Revista Cubana de Endocrinolog?-a , 2002,
Abstract: 19 women with premature ovarian failure that were seen at the physician's office due to secondary hypergonadotropic amenorrhea were studied to determine the existence of some degree of ovarian endocrine reserve. a detailed medical history was taken and complementary examinations were made to define the cause. the basal levels of follicle-stimulating hormone (fsh), luteinizing hormone (lh), estradiol (e2), prolactin (prl), and thyrotropin (tsh) were determined.the steroideal ovarian reserve was also determined by the dynamic test of hypophyseal inhibition of gonadotropins (gn) with ethynyl estradiol and, later, it was estimulated with gonadotropic menopausic hormone (gmh).the basal levels of fsh, lh, e2, testosterone (t) and androstenedione (a'd) were calculated during inhibition and after the stimulation with gmh. it was found that the mean basal levels of fsh were higher than those of lh, the levels of e2 were low and prl was normal on analyzing them as a group. the mean basal level of e2 was low and there was no increase of its mean levels after the stimulation with gmh. the mean basal levels of t were normal, unlike a'd that was low. no rise was observed poststimulation on being analyzed as a group. it was proved that 52.6 % of these patients have an ovarian estrogenic reserve, whereas only 20 % have an androgenic reserve. there were no important differences in the results of the dynamic test on dividing patients into 2 groups, according to the chronological age, time of amenorrhea and cause of pof, excepting that the reserve of t that was only found in those of idiopathic cause, which was not observed in those of immunological cause.
Gonadotropinas y sexoesteroides en mujeres posmenopáusicas del círculo de abuelos
Lozano álvarez,Elio; Padrón Durán,Rubén S; Seuc Jo,Armando;
Revista Cubana de Medicina General Integral , 1997,
Abstract: some of the factors that may influence the hormones of reporduction during the climaterium have been evaluated in recent publications. no research has been done in our country on this topic and that's why this study eas desingned aimed at knowing the relation existing between the postmenopausal hormonal levels sample of 134 postmenopausal women from an urban health area was taken and divided according to their participation in such a circle (67 in each group). the following hormones were detemined by radioimmunoassay: fsh, lh, porlactin, testosterone, estradiol, androstenedione and 17-hydroxyprogesterone (17 oh-p). prolactin was higher in those women who do not take part in the activities of the grandparents' circle; whereas testosterone and 17 oh-p were lower compared with the group participating in the activities. no difference was found in the rest of the hormones. according to these results the activities carried out by these women at the grandparents' circle influence the levels of some of the reproduction hormones, which may have favorable effects for health, on reducciong stress, and particularly on osteoporosis that appears during this period of life.
Caracterización de la lactancia materna en un área urbana
Ovies Carballo,Gisel; Santana Pérez,Felipe; Padrón Durán,Rubén S;
Revista Cubana de Medicina General Integral , 1999,
Abstract: a descriptive and cross-sectional study of 872 women who lived in an urban area and had given birth from 1 to 12 months before was conducted in order to know the duration, pattern of breast feeding, and the causes to abandon it. 1.1 % of these women never started breast feeding due to agalactia. women began to breast feed their children in an average time between 1 and 15 days. among those who had abandoned breast feeding at the time of the study the mean time of duration was 108.5 days. the life table technique was applied to the group that was not breast feeding so as to determine the continuity rate and the risk of leaving breast feeding. in the first case there is only 51 % of probability to continue lactating from 4 to 5 months, and in the same period the weaning risk is 0.83 %. the most frequent reason to leave this practice was the complete loss of milk. only 32.6 % of the studied population used breast feeding exclusively. it is concluded that there is a high trend to abandon breast feeding early and, mainly, the exclusive one
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