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Search Results: 1 - 10 of 463564 matches for " Gilda Monteagudo Pe?a "
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Bases genéticas del síndrome de ovarios poliquísticos
Ovies Carballo,Gisel; Martínez de Sandelices,Alicia; Monteagudo Pea,Gilda; Sardi?as Díaz,Irelys;
Revista Cubana de Endocrinolog?-a , 2011,
Abstract: the syndrome of polycystic ovaries is the endocrine disorder involving more the reproductive sphere of the woman in fertile age, its causes are unknown with accuracy, but most of experts coincide in propose that it is a multifactor entity where the genetic factor more and more have a great significance. in past years, it has been possible to identify some genes involved in the pathogenic processes of this syndrome and among the more important are included those codifying for enzymes of the steroidogenesis, for the insulin receptor and other hormones related to the insulin action, as well as the gonadotropins and its receptors, features that are the aim of present review.
Patrón hormonal de mujeres con diagnóstico clínico y ecográfico del síndrome de ovarios poliquísticos
Acosta Cede?o,Alina; Monteagudo Pea,Gilda; Menocal Alayón,Ahmed;
Revista Cubana de Endocrinolog?-a , 2004,
Abstract: the polycystic ovary syndrome (pos) is a disorder of non well defined etiology with an aberrant hormonal pattern. the results of a descriptive cross-sectional study in which 30 women with clinical hyperandrogenism and at least 2 echographic elements suggestive of pos that were determined testosterone (t), androstenedione (ad), dihydroepiandrosterone (dhea) and its sulfate (dheas), follicle stimulating hormone (fsh) and luteinizing hormone (lh), were shown. descriptive statiscians and person's correlation test were used to analyze the results. the behavior of gonadotropins was very variable. the fsh was diminished in 3 cases, normal in 24 and increased in 3, with normal mean values (5.45 ui/l). the lh had values under the range of normality in 1 case, normal in 10 and high in 19, and an elevated mean value (12.49 ui/l). the ratio lh/fsh was over 3 in 14 patients (46.6 %). the mean values of all the androgens, excepting dheas were high; in 46.6 % of the cases it was found a rise of more than one androgen, and biochemical hyperandrogenism was not proved in 4 cases. the ad and the dhea were the most frequently rised androgens (50 % each one), followed by the t (30.0) and the dhea (10.0). no correlation was observed among the studied variables. it was concluded that the association of clinical hyperandrogenism and echographic signs of pos did not guarantee uniformity in the hormonal behavior, so it is necessary to continue working to determine the diagnostic element that identifies the syndrome really.
Hipertiroidismo subclínico Subclinical hyperthyroidism
Lisbet Rodríguez Fernández,Marelys Yanes Quesada,Alina Acosta Cede?o,Gilda Monteagudo Pea
Revista Cubana de Endocrinología , 2009,
Abstract: El hipertiroidismo subclínico se define por la presencia de niveles disminuidos o no detectables de tirotropina, asociados a concentración de tetrayodotironina y triyodotironina libres dentro de parámetros normales. Su prevalencia en la población varía entre un 0,5 y un 16 % aproximadamente, y es el tratamiento con levotiroxina sódica la causa más frecuente. No siempre resulta tan asintomático, y las afectaciones principales ocurren sobre el sistema cardiovascular y óseo. Esta condición médica puede ser reversible espontáneamente. Por lo controversial del tema, el presente trabajo trata los aspectos clínicos más relevantes y la conducta a seguir. Subclinical hyperthyroidism is defined by presence of decreased o non-detected levels of thyrotropin, associated with free concentrations of tetraiodothyronine and triiodothyromime within normal parameters. Its prevalence in population differs between 0,5 % and 16 % approximately, and the sodium Levothyroxine treatment is the more frequent cause. Not always it is so asymptomatic, and main affections occur on cardiovascular and osseous system. This medical condition may be spontaneously reversible. Due to controversial of this topic, present paper approaching the more significant clinical features and the strategy to go on.
Cirugía genital: impacto psicológico y sexual. Presentación de una paciente Genital surgery: psychological and sexual impact. A case report
Adriana Agramonte Machado,Loraine Ledón Llanes,Gilda Monteagudo Pea,Madelín Mendoza Trujillo
Revista Cubana de Endocrinología , 2007,
Abstract:
Bases genéticas del síndrome de ovarios poliquísticos Genetic bases of polycystic ovary syndrome
Gisel Ovies Carballo,Alicia Martínez de Sandelices,Gilda Monteagudo Pea,Irelys Sardi?as Díaz
Revista Cubana de Endocrinología , 2011,
Abstract: El síndrome de ovarios poliquísticos es el trastorno endocrino que más afecta la esfera reproductiva de la mujer en la edad fértil, sus causas se desconocen con exactitud, pero la mayoría de los expertos coinciden en plantear que es una entidad multifactorial, en la que los factores genéticos cada vez cobran mayor importancia. En los últimos a os se han identificado varios genes involucrados en los procesos patogénicos de este síndrome, y dentro de estos, los más importantes son aquellos que codifican para enzimas de la esteroidogénesis, para el receptor de insulina y otras hormonas relacionadas con la acción de la insulina, así como las gonadotropinas y sus receptores, aspectos sobre los cuales trata la siguiente revisión. The syndrome of polycystic ovaries is the endocrine disorder involving more the reproductive sphere of the woman in fertile age, its causes are unknown with accuracy, but most of experts coincide in propose that it is a multifactor entity where the genetic factor more and more have a great significance. In past years, it has been possible to identify some genes involved in the pathogenic processes of this syndrome and among the more important are included those codifying for enzymes of the steroidogenesis, for the insulin receptor and other hormones related to the insulin action, as well as the gonadotropins and its receptors, features that are the aim of present review.
Deficiencia androgénica en hombres de 60 a os y más del área de salud Vedado Androgen deficiency in men aged 60 or more from Vedado health area
Eduardo álvarez Seijas,Gilda Monteagudo Pea,Manuel Gómez Alzugaray,Celeste Arranz Calzado
Revista Cubana de Endocrinología , 2009,
Abstract: El declinar de la función testicular propia del envejecimiento ha adquirido relevancia en los últimos a os, sin embargo aún no se conoce su prevalencia, ni existe uniformidad para el diagnóstico. Se realizó un estudio descriptivo transversal con el objetivo de determinar la prevalencia y características clínico-hormonales del déficit androgénico en varones de 60 a os y más. Se incluyeron 70 sujetos de un área de salud, seleccionados mediante muestreo aleatorio estratificado polietápico, a los cuales se interrogó sobre la presencia de síntomas de deficiencia androgénica, se les realizó examen físico general y genital y determinaciones de testosterona total, hormona luteinizante y hormona folículo estimulante en sangre periférica. De acuerdo con las concentraciones de la testosterona se dividieron en 2 grupos: a) sujetos con deficiencia androgénica y b) sujetos sin deficiencia androgénica. Los que presentaron déficit androgénico tenían un peso significativamente superior, una proporción mayor de obesidad y una talla significativamente inferior. Los síntomas de déficit androgénico fueron frecuentes, los refirieron indistintamente los integrantes de ambos grupos y se presentaron independientemente de las concentraciones de las hormonas sexuales. En general, las gonadotropinas estaban aumentadas fundamentalmente a expensas de hormona folículo estimulante y su comportamiento fue independiente de las concentraciones de testosterona. Decline of testicular function typical of aging has acquired relevance in past years, however yet it is unknown its prevalence and there is not evenness for its diagnosis. A cross-sectional and descriptive study was made to determine the prevalence and clinical-hormonal features of androgen deficit in males aged 60 or more. Included are 70 subjects from a health area selected by multistage stratified randomized sampling that were interrogated about presence of androgen deficiency syndrome and underwent a physical and genital examination and total testosterone determinations, luteinizing hormone and follicle-stimulating hormone in peripheral blood. According the testosterone concentrations they were divided into two groups: a) subjects presenting with androgen deficiency and b) subjects without this type of deficiency. Those with androgen deficit had a higher weight, a higher obesity ratio, and a significantly lower height. The symptoms of androgen deficit were frequent, recounted indiscriminately by both groups and independently of sexual hormone concentrations. Generally, gonadotropins were increased mainly at the expense of folli
Patrón hormonal de mujeres con diagnóstico clínico y ecográfico del síndrome de ovarios poliquísticos Hormonal pattern of women with clinical and echographic diagnosis of polycystic ovary syndrome
Alina Acosta Cede?o,Gilda Monteagudo Pea,Ahmed Menocal Alayón
Revista Cubana de Endocrinología , 2004,
Abstract: El síndrome de ovarios poliquísticos (SOP) es un trastorno de etiología no bien precisada con un patrón hormonal aberrante. Se muestran los resultados de un estudio descriptivo transversal en el que se incluyeron 30 mujeres con hiperandrogenismo clínico y al menos 2 elementos ecográficos sugestivos del SOP, a quienes se les determinó testosterona (T), androstenediona (Ad), dihidroepiandrosterona (DHEA) y su sulfato (DHEAs), hormona folículo estimulante (FSH) y hormona luteinizante (LH). Se emplearon estadígrafos descriptivos y prueba de correlación de Person para el análisis de los resultados. El comportamiento de las gonadotropinas fue muy variable: la FSH estuvo disminuida en 3 casos, normal en 24 y aumentada en 3, con valores medios normales (5,45 UI/L); la LH tuvo valores inferiores al rango de la normalidad en 1 caso, normales en 10 y elevados en 19, y un valor medio elevado (12,49 UI/L); la relación LH/FSH fue mayor de 3 en 14 pacientes (46,6 %). Los valores medios de todos los andrógenos, excepto la DHEAs, estuvieron elevados; en el 46,6 % de los casos se encontró elevación de más de 1 andrógeno y en 4 casos no se demostró hiperandrogenismo bioquímico; la Ad y la DHEA fueron los andrógenos más frecuentemente elevados (50 % cada una), seguidos de la T (30,0) y la DHEAs (10,0). No se demostró correlación entre ninguna de las variables estudiadas. Se concluye que la asociación de hiperandrogenismo clínico y signos ecográficos del SOP no garantiza uniformidad en el comportamiento hormonal, por lo que se debe continuar trabajando para determinar el elemento diagnóstico que verdaderamente identifique el síndrome. The polycystic ovary syndrome (POS) is a disorder of non well defined etiology with an aberrant hormonal pattern. The results of a descriptive cross-sectional study in which 30 women with clinical hyperandrogenism and at least 2 echographic elements suggestive of POS that were determined testosterone (T), androstenedione (Ad), dihydroepiandrosterone (DHEA) and its sulfate (DHEAs), follicle stimulating hormone (FSH) and luteinizing hormone (LH), were shown. Descriptive statiscians and Person's correlation test were used to analyze the results. The behavior of gonadotropins was very variable. The FSH was diminished in 3 cases, normal in 24 and increased in 3, with normal mean values (5.45 UI/L). The LH had values under the range of normality in 1 case, normal in 10 and high in 19, and an elevated mean value (12.49 UI/L). The ratio LH/FSH was over 3 in 14 patients (46.6 %). The mean values of all the androgens, excepting DHEAs were high; in 46.6
Síndrome metabólico y prediabetes Metabolic syndrome and prediabetes
Raúl Orlando Calderín Bouza,Gilda Monteagudo Pea,Marelys Yanes Quesada,Julieta García Sáez
Revista Cubana de Endocrinología , 2011,
Abstract:
Evaluación de las alteraciones lipídicas en el síndrome de ovarios poliquísticos y su relación con la resistencia a la insulina
García García,Yudit; Monteagudo Pea,Gilda; Padrón Durán,Rubén S.; González Suárez,Roberto;
Revista Cubana de Endocrinolog?-a , 2010,
Abstract: introduction: the polycystic ovaries syndrome to exceed the reproductive axis due to its frequent association with metabolic and cardiovascular alterations. objective: based on above mentioned a cross-sectional and descriptive study was conducted to determine the frequency and the characteristic of lipid alterations en a group of women diagnosed with polycystic ovaries and its relation to alterations in insulin-sensitivity. methods: twenty three women were studied according to androgen excess society criteria, hormonal and lipid determinations were made as well as fasting glycemia and insulinemia to assess the insulin-sensitivity. results: the 95,6% of patients presenting with dyslipemia. the more frequent lipid alterations were a decrease of the high density lipoproteins (chdl) and apolipoproteins (apo) (91,3 and 87,0 %, respectively) whereas the increase of triglycerides(tg) and the total cholesterol (tc) were infrequent (13 and 4,3 %, respectively). the estimated lipid rates: tg/chdl, ct/chdl, chdl/cldl and apo b/a-i had higher mean values in women with insulin-resistance; the apo b/a-i rate had the greater difference in women with insulin-resistance and without it. conclusion: the lipid alterations frequency in study women suggest that in expression of polycystic ovaries syndrome could be involved many metabolic and hormonal factors.
Evaluación de la sensibilidad a la insulina en el síndrome de ovarios poliquísticos
García García,Yudit; Monteagudo Pea,Gilda; Padrón Durán,Rubén S.; González Suárez,Roberto;
Revista Cubana de Endocrinolog?-a , 2009,
Abstract: introduction: women with polycistic ovary syndrome have a increasing risk of insulin resistance, dyslipidemia, obesity, hypertension and type 2 diabetes mellitus; thus, with higher likelihood to develop cardiovascular disease. objective: to determine the frequency and features of insulin sensitivity disorders in a group of women with polycistic ovary syndrome. methods: twenty three women with this diagnosis were studied according to the androgen excess society (aes) criteria,underwent basal glycemia and insulinemia determinations and during frequently sampled intravenous glucose tolerance test). several insulin sensitivity and insulin resistance mathematic indexes were calculated. results: sixty-five percent of women had insulin resistance (homa-ir 3 3.22 rate). analysis of area under the curve of insulin during the test revealed that women with insulin resistance had higher insulinemia rates in baseline state and post-stimulation;in both groups concentrations were similar to the initial ones at the end of test. glycemia and insulinemia 0-10 areas and insulin area were higher in women with insulin resistance. all indexes including io/go, firi, isi, belfiore, bennet and quicki had a good correlation with homa-ir. conclusions: insulin resistance and hyperinsulinism frequency in women with policystic ovary syndrome was high and the fasting insulin resistance assessment may to predict the response during the glucose-intravenous stimulation.
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