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Cognitive Remediation in Schizophrenia: Current Status and Future Perspectives
Stefano Barlati,Giacomo Deste,Luca De Peri,Cassandra Ariu,Antonio Vita
Schizophrenia Research and Treatment , 2013, DOI: 10.1155/2013/156084
Abstract: Objectives. This study is aimed to review the current scientific literature on cognitive remediation in schizophrenia. In particular, the main structured protocols of cognitive remediation developed for schizophrenia are presented and the main results reported in recent meta-analyses are summarized. Possible benefits of cognitive remediation in the early course of schizophrenia and in subjects at risk for psychosis are also discussed. Methods. Electronic search of the relevant studies which appeared in the PubMed database until April 2013 has been performed and all the meta-analyses and review articles on cognitive remediation in schizophrenia have been also taken into account. Results. Numerous intervention programs have been designed, applied, and evaluated, with the objective of improving cognition and social functioning in schizophrenia. Several quantitative reviews have established that cognitive remediation is effective in reducing cognitive deficits and in improving functional outcome of the disorder. Furthermore, the studies available support the usefulness of cognitive remediation when applied in the early course of schizophrenia and even in subjects at risk of the disease. Conclusions. Cognitive remediation is a promising approach to improve real-world functioning in schizophrenia and should be considered a key strategy for early intervention in the psychoses. 1. Introduction Impairments in a wide range of cognitive abilities have been consistently reported in individuals with schizophrenia [1]. In the recent past, the Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) project has identified seven distinct cognitive domains that are impaired in patients with schizophrenia: speed of processing, attention/vigilance, working memory, verbal and visual learning, reasoning and problem solving, and social cognition [2]. Moreover, in the third meeting of the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) project, it was agreed that six areas or cognitive domains suffered impairment in schizophrenia: perception, working memory, attention, executive functions, long-term memory, and social cognition [3]. Social cognitive deficits include impairments in facial affect recognition, in perceiving and interpreting social cues, theory of mind (ToM), and the ability to make appropriate causal attributions for events [4]. Both neurocognitive and social cognitive deficits are thought to underlie the severe functional disabilities associated with schizophrenia, and several studies have
Behavioural intention and factors influencing intention of Ethiopian mothers to expose infants to sunshine
Sileshi Lulseged, Catherine Deste
Ethiopian Journal of Health Development , 2002,
Abstract: [Ethiop. J. Health Dev. 2002;16(1): 31-40]
Proposal of an Innovative Business Model for Customized Production in Healthcare  [PDF]
Golboo Pourabdollahian, Giacomo Copani
Modern Economy (ME) , 2014, DOI: 10.4236/me.2014.513107
Abstract: The growth of aging population in developed countries necessitates a better performance of the healthcare system in order to improve the healthy life expectancy of elderly people. Such a progress can be achieved both through improved services and medical products. Accordingly, providing patients with customized medical devices that are designed and produced based on individual requirements of each patient can be seen as a proper solution. In this regard, the emerging manufacturing technologies such an additive manufacturing not only facilitate customized production in healthcare sector, but also can change the role of the hospital from a solely user to a producer. However, successful pursuit of such strategy requires implementation of a new business model as a supporting tool. This paper aims at proposing an innovative business model to support hospitals for customized production in healthcare.
Supercritical Water Technology Applied to the Purification of Waters Contaminated by Toxic Micro-Polluting Organic Compounds  [PDF]
Gabriele Di Giacomo, Luca Taglieri
Journal of Water Resource and Protection (JWARP) , 2012, DOI: 10.4236/jwarp.2012.47053
Abstract: Purification of water contaminated by toxic organic compounds at low and very low concentration is a quite interesting challenge from both the technical and the economical point of view. In fact, the direct destruction of organic compounds dissolved in very diluted aqueous solution is very costly and hardly achievable. To overcome this problems it was studied and developed a new water purification process which is made of three steps: a) removal of the diluted and toxic polluting compounds by adsorption on activated carbon beds operating at ambient P ant T; b) regeneration of the exhausted carbon bed with supercritical water in order to obtain a mixture of water and polluting compounds signifi-cantly more concentrated than the contaminated liquid water; c) destruction of the toxic compounds in a continuous Supercritical Water Oxidation Reactor. Step a) was studied at laboratory scale in order to obtain all the required information for modeling the adsorption operation; step b) was modeled by using literature experimental data and, step c) was validated at pilot plant scale. In all the above mentioned steps, phenol was used as representative of polluting compounds.
Neuromorphic VLSI Models of Selective Attention: From Single Chip Vision Sensors to Multi-chip Systems
Giacomo Indiveri
Sensors , 2008, DOI: 10.3390/s8095352
Abstract: Biological organisms perform complex selective attention operations continuously and effortlessly. These operations allow them to quickly determine the motor actions to take in response to combinations of external stimuli and internal states, and to pay attention to subsets of sensory inputs suppressing non salient ones. Selective attention strategies are extremely effective in both natural and artificial systems which have to cope with large amounts of input data and have limited computational resources. One of the main computational primitives used to perform these selection operations is the Winner-Take-All (WTA) network. These types of networks are formed by arrays of coupled computational nodes that selectively amplify the strongest input signals, and suppress the weaker ones. Neuromorphic circuits are an optimal medium for constructing WTA networks and for implementing efficient hardware models of selective attention systems. In this paper we present an overview of selective attention systems based on neuromorphic WTA circuits ranging from single-chip vision sensors for selecting and tracking the position of salient features, to multi-chip systems implement saliency-map based models of selective attention.
Improving the Reliability of Frequency Domain Simulators in the Presence of Homogeneous Metamaterials - a Preliminary Numerical Assessment
Giacomo Oliveri
PIER , 2012, DOI: 10.2528/PIER11100808
Abstract: The accuracy of the finite difference frequency domain (FDFD) method in the solution of canonical waveguide discontinuity problems involving complementary or nearly complementary metamaterials (MTMs) is analytically discussed. It is shown that the good accuracy of the method (in comparison with other frequency-domain techniques) is due to the intrinsic approximation which it introduces in the finite-difference discretization of sharp dielectric interfaces. By exploiting such a result, a perturbation algorithm is proposed for the reliable modeling of MTMs devices when other frequency domain numerical methods are at disposal. A preliminary numerical analysis is carried out to assess the reliability and accuracy of the proposed modeling approach when canonical scattering problems are at hand.
The Costs and Promise of Turkish Accession to the EU
Giacomo Luciani
Revista CIDOB d'Afers Internacionals , 2006,
Abstract: Currently, the EU as a whole finds itself in an economic context in which growth is not very stimulating, although the differences by country are significant, principally between the new and old Member States. From this perspective, the author offers an economic analysis of the costs, and opportunities, of Turkey’s accession to the communityfamily, both for that country and for the EU.
Simulation of Supply-Chain Networks: A Source of Innovation and Competitive Advantage for Small and Medium-Sized Enterprises
Giacomo Liotta
Technology Innovation Management Review , 2012,
Abstract: On a daily basis, enterprises of all sizes cope with the turbulence and volatility of market demands, cost variability, and severe pressure from globally distributed competitors. Managing uncertainty about future demand requirements and volumes in supply-chain networks has become a priority. One of the ways to deal with uncertainty is the utilization of simulation techniques and tools, which provide greater predictability of decision-making outcomes. For example, simulation has been widely applied in decision-making processes related to global logistics and production networks at the strategic, tactical, and operational levels, where it is used to predict the impact of decisions before their implementation in complex and uncertain environments. Large enterprises are inclined to use simulation tools whereas small and medium-sized enterprises seem to underestimate its advantages. The objective of this article is to emphasize the relevance of simulation for the design and management of supply-chain networks from the perspective of small and medium-sized firms.
They prefer Witches Preferiscono le streghe
Giacomo Debenedetti
Between , 2011,
Abstract: Gli Italiani preferiscono le streghe, o le maghe e le fattucchiere, quando debbono guarirsi l’anima, scacciarsi di dosso i diavoli che paralizzano la vita. Nel caso, s’intende, che abbiano rinunziato all’assistenza del confessore. Meglio allora una fattura, che un lungo e costoso trattamento psicologico. Questo aiuta a capire perché Freud e la psicanalisi abbiano fatto, tra noi, così poca fortuna.
The Making of a Biogeographer: the life of Jack Briggs
Giacomo Bernardi
Frontiers of Biogeography , 2010,
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