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Search Results: 1 - 10 of 623 matches for " Gholamreza Asghari "
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Antimicrobial Activity and Chemical Composition of Essential Oil From the Seeds of Artemisia aucheri Boiss
Gholamreza Asghari,Mohamad Jalali,Ehsan Sadoughi
Jundishapur Journal of Natural Pharmaceutical Products , 2012,
Abstract: Background: Artemisia aerial parts are well known for antimicrobial activities including anti malaria..Objectives: This study was carried out to evaluate the antimicrobial activity and chemical composition of essential oil from the seeds of Artemisia aucheri Boiss (Asteraceae)..Materials and Methods: Essential oil was extracted from the powdered seeds of Artemisia aucheri by hydrodistillation. Antimicrobial activity against five bacterial species was tested using the disc diffusion method, and the chemical composition of the essential oil was analyzed by gas chromatography-mass spectrometry (GC-MS)..Results: The essential oil of Artemisia aucheri seed showed activity against Escherichia coli, Staphylococcus aureus, and Listeria monocytogenes. The essential oil constituents identified by GC-MS were as follows: decane, ρ-cymene, 1,8-cineole, linalool, ρ-mentha-8-ol, triene, borneol, lavandulol, bornyl acetate, chrysanthenyl acetate, dehydro aromadenderene, and caryophyllene oxide. Most of these compounds are also found in the aerial parts of Artemisia aucheri..Conclusions: Variation in the compositions of essential oils from Artemisia aucheri, and thus variation in the antimicrobial activity of these oils, may be due to the plant parts used for essential oil prepration.
Biotransformation of Aromatic Aldehydes by Cell Cultures of Peganum harmala L. and Silybum marianum (L.) Gaertn
Gholamreza Asghari,Gholamali Saidfar,Shohreh Mahmudi
Iranian Journal of Pharmaceutical Research , 2004,
Abstract: Many aldehydes are important components of natural flavours. They are used in food, cosmetic, and biomedical industries in large amounts. Plant cells or microorganisms carry out their production by biotransformation, which is one of the biotechnological methods that allow them to be defined as 'natural'. Cell cultures of Silybum marianum and Peganum harmala have been studied with a view to investigat their abilities to produce flavonolignans and -carboline alkaloids respectively. However, we have isolated S. marianum and P. harmala culture strain, which are able to metabolise several aromatic aldehydes. Ten culture strains derived from S. marianum and P.harmala were examined for their ability to biotransform exogenous aromatic aldehyde compounds, including benzaldehyde, 2- methoxybenzaldehyde, 4-methoxybenzaldehyde, cinnamaldehyde and 3-methoxy, 4-hydroxy benzaldehyde. Callus cultures of Silybum marianum and Peganum harmala were established from seedlings, and healthy suspensions were grown using the Murashige and Skoog medium. Exogenous aromatic aldehydes were fed to S. marianum and P. harmala cell suspension cultures. Biotransformation reactions were detected over 24 h of incubation. The cultures then extracted with dichloromethane and extracts subjected to GC and GC-MS analysis. The S. marianum cultured cells in this study exhibit greater selectivity in the reduction of aromatic aldehydes than P. harmala culturedcells. The ability of cultured plant cells to biotransform substrate appears to be dependent on the culture strains as well as the nature and position of the substituent on the aromatic ring.
Seasonal Variation of Mono- and Sesquiterpenes in the Essential Oil of Pycnocycla Spinosa Decne. Exboiss
Gholamreza Asghari,Gholamali Houshfar,Zahra Mahmoudi
Iranian Journal of Pharmaceutical Research , 2002,
Abstract: Pycnocycla spinosa aerial parts were collected weekly during four-month growth.Hydrodistillation and gas chromatography coupled with mass spectroscopy techniques were used for essential oil and sesquiterpenes investigation. Thirty-four components were identified,of which the characteristic sesquiterpenes were α-copaene, caryophyllene, α-humulene, β-ionene, d-cadinene, α-calacorene, caryophyllen oxide, α-cadinol, and β-eudesmol. The content of β-eudesmol in the essential oil varied 1.9-9.17%, and of α-cadinol did 0-5.59%. Plant harvested in Jun provided essential oil with high caryophyllen oxide. These results may indicate that essential oil of differ qualities can be obtained according to the harvest time of the plant
Characterization of Volatile Constituents from Aerial Parts of Varthemia persica DC (var. persica)
Nasrollah Ghasemi,Gholamreza Asghari,Mohammadreza Shams Ardakani,Amir Siahpoush
Iranian Journal of Pharmaceutical Research , 2003,
Abstract: The volatile constituents of the aerial parts of Varthemia. persica DC. var. persica, growing wild in Iran, were investigated by GC-MS. Sixty seven constituents were identified. δ-Cadinene (9.7%), Selin-11-en-4-α-ol (5.30%), Germacrene D (4.9%), Bicyclogermacrene (4.7%),α-Muurolene (4.7%), β-Eudesmol (4.52%), β-Himachalen oxide (3.6%), γ-Eudesmol (3.54%), β-Bourbonene (3.21%) were found to be the major constituents of the oil respectively
Composition of Essential Oil of Artemisia persica Boiss. from Iran
Omid Sadeghpour,Gholamreza Asghari,Mohammad Reza Shams Ardekani
Iranian Journal of Pharmaceutical Research , 2004,
Abstract: The steam-distilled essential oil from Artemisia persica growing wild in Iran was analyzed by GC/MS. In all 50 compounds were identified; Davanone (60.56%), Cis Chrysanthenyl acetate (8.65%), Limonene (5.68%), α Pinene (3.74%), Davanone ether isomer + (3.6%) and α Thujene (3.6%) were the main components of the oil respectively
Evaluation of the effect of Elaeagnus angustifolia drug film on gag reflex
Ehsan Hekmatian,Gholamreza Asghari,Rahim Bahri Najafi,Seyed Hosein Moosavi
Journal of Isfahan Dental School , 2011,
Abstract: Introduction: Gag reflex is one of the most common problems during dental procedures, especially during radiography and impression taking. The aim of this study was to evaluate the effect of Elaeagnus angustifolia drug film on gag reflex. Materials and methods: One hundred patients referring to the Radiology Department of Isfahan School of Dentistry were selected for the purpose of this double-blind clinical trial and randomly divided into two groups. The gag reflex was provoked and then in 50 patients, medication A (placebo) and in 50 others medication B containing Elaeagnus angustifolia were placed for 3 minutes in zones which were trigger zones for the gag reflex. Then the patients’ gag reflex was evaluated again. Data was analyzed with Wilcoxon, Mann-Whitney and chi-squared tests (α=0.05).Results: In group A (placebo), frequency of distribution of gag reflex in the soft palate, tonsils and tongue were not significantly different before and after drug use. However, in group B, frequency of distribution of gag reflex exhibited significant differences in the tonsils (p value < 0.001) and soft palate (p value < 0.003) after drug application. In addition, there were no significant differences in sex distribution between the two groups.Conclusion: The results of the present study showed that a thin film of a medication containing Elaeagnus angustifolia has a positive effect on gag reflex in the tonsil and soft palate areas, and it can be used during dental procedures such as radiography procedures. Key words: Gagging, Drug, Placebo, Radiography.
Evaluation of cardiovascular effect of Pycnocycla spinosa Decne. exBoiss. var. spinosa extract in anaesthetized rat
Hassan Sadraei,Gholamreza Asghari,Valiollah Hajhashemi,Mostafa Nezami
DARU : Journal of Pharmaceutical Sciences , 2006,
Abstract: Hydroalcoholic extract of Pycnocycla spinosa Decne. exBoiss. var. spinosa has in vitro spasmolytic action, and at oral dose of 250 g/kg inhibits castor oil induced diarrhoea in mice. In this investigation, effects of P. spinosa var. spinosa extract in comparison with nifedipine on blood pressure and heart rate in animal model was studied. Injection of three bolus doses of P. spinosa var. spinosa extract (100 g/kg, 500 g/kg and 1mg/kg) into the jugular vein, temporary reduced blood pressure and heart rate. However, soon after completion of extract administration blood pressure and heart rate returned to normal. Nifedipine on the other hand caused a sustained reduction in blood pressure and decreased heart rate compared with the control group. From this study it was concluded that P. spinosa var. spinosa extract at antidiarrhoeal dose has no significant effect on blood pressure and heart rate.
Mechanical properties of radial bone defects treated with autogenous graft covered with hydroxyapatite in rabbit
Sharifi, Davood;Khoushkerdar, Hamid Reza;Abedi, Gholamreza;Asghari, Ahmad;Hesaraki, Saeed;
Acta Cirurgica Brasileira , 2012, DOI: 10.1590/S0102-86502012000300009
Abstract: purpose: to determine biomechanical property of autogenous bone graft covered with hydroxyapatite in the defect of radial bone in rabbit. methods: eighteen adult male new zealand white rabbits were used which were divided into three groups (i, ii, iii) of six rabbits each. a segmental bone defect of 10 mm in length was created in the middle of the right radial shaft under general effective anesthesia in all rabbits and were stabilized using mini-plate with four screws. the defects in group i were left as such without filler, whereas in group ii the defect were filled up with harvested 10 mm rib bone and in group iii the defect were packed with rib bone covered with nano-hydroxyapatite. all rabbits in three groups were divided into two subgroups (one month and three months duration with three rabbits in each one). results: the mechanical property and the mean load for fracturing normal radial bone was recorded 388.2±6 n whereas it was 72.4±12.8 n for group i in 1 month duration which was recorded 182.4±14.2 n for group ii and 211.6±10.4 n for group iii at the end of 1 month. these values were 97.6±10.2 n for group i and 324.6±8.2 n for group ii and 372.6±17.4 n for group iii at the end of three months after implantation. conclusion: implantation of autologous graft covered with hydroxyapatite indicated to have positive effect in integral formation of qualitative callus at the site of fracture and early re-organization of callus to regain mechanical strength too.
Providing Appropriate Solutions for Treatment and Sewage of Wastewaters in Cargo Terminals of Shorelines: An Emphasis on Terminal Bandar  [PDF]
Gholamreza Mansourri
Open Journal of Ecology (OJE) , 2016, DOI: 10.4236/oje.2016.62009
Abstract: Low volume of produced wastewater and specific regional, environmental and economic condition in small communities determines the methods of treatment of sewage in such communities including shorelines of Bandar Abbas, Bushehr, Imam Khomeini Harbor and Chabahar Harbor. Ineffective methods of treating and sewing wastewater in aforesaid terminals as well as limitations of methods of wastewater treatment such as high level of underground waters doubled the necessity of considering alternative methods. In this paper, investigation of current conditions was performed through field observations and data collection regarding wastewater production in terminals and determination of qualitative specifications using sampling and carrying out pH, TSS, COD, BOD and temperature tests from inlet to outlet of available sewage system of abovementioned terminals and comparison with environmental organization standards corresponding to wastewater sewage and it was found out that conditions of available systems of wastewater treatment are not suitable. In this regard, modifying solutions for the sake of improving performance of systems of wastewater treatment of terminals is presented in this research. Finally, for wastewater treatment system of Bandar Abbas terminal, if there is no limitation for allocating lands, it is recommended to use artificial canebrake system with underground flow.
Assessment of Groundwater Quality and its Suitability for Drinking and Agricultural Uses in the Oshnavieh Area, Northwest of Iran  [PDF]
Nosrat Aghazadeh, Asghar Asghari Mogaddam
Journal of Environmental Protection (JEP) , 2010, DOI: 10.4236/jep.2010.11005
Abstract: The Oshnavieh plain is part of the West Azarbaijan province, which is located; 100 km south of Urmia City, northwestern of Iran, and its groundwater resources are developed for water supply and irrigation purposes. In order to evaluate the quality of groundwater in study area, 31 groundwater samples were collected and analyzed for various parameters. Physical and chemical parameters of groundwater such as electrical conductivity, pH, total dissolved solids, Na, K, Ca, Mg, Cl, HCO3, CO3, SO4, NO3, NH3, PO4, Fe, F were determined. Chemical index like percentage of sodium, sodium ad-sorption ratio, and residual sodium carbonated, permeability index (PI) and chloroalkaline indices were calculated. Based on the analytical results, groundwater in the area is generally fresh and hard to very hard. The abundance of the major ions is as follows: HCO3 > SO4 > Cl and Ca > Mg > Na > K. The dominant hydrochemical facieses of groundwater is Ca-HCO3 and Ca-Mg-HCO3 type. According to Gibbs diagrams samples fall in the rock dominance field and the chemical quality of groundwater is related to the lithology of the area. The results of calculation saturation index by computer pro-gram PHREEQC shows that the nearly all of the water samples were saturated to undersaturated with respect to carbon-ate minerals and undersaturated with respect to sulfate minerals. Assessment of water samples from various methods in-dicated that groundwater in study area is chemically suitable for drinking and agricultural uses. Fluoride and nitrate are within the permissible limits for human consumption and crops as per the international standards.
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