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Search Results: 1 - 10 of 18 matches for " Gherpelli "
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Tratamento das cefaléias
Gherpelli, José Luiz Dias;
Jornal de Pediatria , 2002, DOI: 10.1590/S0021-75572002000700002
Abstract: objective: to perform a bibliographic review about headache treatment in childhood and adolescence. sources: articles were searched through medline database using the terms: migraine, or headache, childhood, or adolescence, and treatment, during the period between 1966 and 2001. review articles and case reports were excluded. only articles dealing with pharmacological, and non-pharmacological treatment of primary headaches were selected. summary of the findings: a total of 104 articles were found; only those reporting results of the case-control studies, or drug vs. placebo, either blind, or open, and that included children, or adolescents were selected. conclusions: only a few controlled studies about the headache treatment were found in the pediatric age group, although primary headaches are frequently seen in clinical practice. therefore they constitute an important subject to be studied. only a few drugs were adequately studied, and in a small number of studies. both acute and prophylactic treatment were addressed.
New Migraine Prophylactic Drug Options
Gherpelli José Luiz Dias
Revista do Hospital das Clínicas , 2002,
Abstract:
Migraine in childhood and adolescence: a critical study of diagnostic criteria and influence of age on clinical findings
GHERPELLI JOSé LUIZ DIAS
Arquivos de Neuro-Psiquiatria , 1998,
Abstract:
Achados incomuns na ultra-sonografia de cranio no período neonatal: importancia clínica
Gherpelli José Luiz Dias
Jornal de Pediatria , 2002,
Abstract:
Prognostic relevance of risk factors for obstetrical brachial plexopathy
Heise, Carlos O.;Gherpelli, José Luiz D.;
Arquivos de Neuro-Psiquiatria , 2006, DOI: 10.1590/S0004-282X2006000100007
Abstract: we did a case-control study to verify if the birthweight, forceps delivery or perinatal asphyxia have any significant effect on the prognosis of obstetrical brachial plexopathy. group a was composed of 25 infants who completely recovered at the age of 6 months. group b was composed of 21 infants who were still not able to remove a blindfold from the face with the affected limb in the sitting position at the age of 12 months. there was no statistical difference of the median birthweight or median first minute apgar score between the groups. there was also no relation between birthweight higher than 4000g, first minute apgar score lower than 6 or forceps delivery with a poor prognosis.
Comparison of chronological and corrected ages in the gross motor assessment of low-risk preterm infants during the first year of life
Restiffe, Ana Paula;Gherpelli, José Luiz Dias;
Arquivos de Neuro-Psiquiatria , 2006, DOI: 10.1590/S0004-282X2006000300013
Abstract: objective: to evaluate the need of chronological age correction according to the degree of prematurity, when assessing gross motor development in preterm infants, during the first year of life. method: cohort, observational and prospective study. alberta infant motor scale (aims) was used to evaluate 43 preterm infants with low risk for motor neurological sequelae, during the first year of corrected age. mean scores were analyzed according to chronological and corrected ages. children with motor neurological sequelae were excluded during follow-up. results: gross motor mean scores in preterm infants tended to be higher when corrected age was used compared with those obtained when using chronological age, during the first twelve months. at thirteen months of corrected age, an overlapping of confidence intervals between corrected and chronological ages was observed, suggesting that from that period onwards correction for the degree of prematurity is no longer necessary. conclusion: corrected age should be used for gross motor assessment in preterm infants during the first year of life.
A prospective randomized double blind placebo controlled crossover study of fluoxetine efficacy in the prophylaxis of chronic daily headache in children and adolescents
Gherpelli, José Luiz Dias;Esposito, Sandro Blasi;
Arquivos de Neuro-Psiquiatria , 2005, DOI: 10.1590/S0004-282X2005000400001
Abstract: thirty-two children (21 female and 11 male), between 7 and 14 years old, with chronic daily headache (cdh) were consecutively included in a prospective, randomized, double blind, placebo controlled crossover study. the patients were divided in group i (fluoxetine vs. placebo), with 17 patients and group ii (placebo vs. fluoxetine), with 15 patients. after one month of baseline headache frequency recording, the patients received fluoxetine in dosages from 0.25 to 0.50 mg/kg for three months. a wash out period of one month was followed by another three months treatment period. results showed a significant decrease in headache frequency in the study period [78% reduction in group i (p<0.025), and 45% reduction in group ii (p=0.025)]. gastrointestinal adverse effects were observed in nine patients (29%) that received fluoxetine, compared with 3 (10%), with placebo. we conclude that fluoxetine efficacy is not higher than placebo in the prophylaxis of cdh in children and adolescents.
Prognostic relevance of risk factors for obstetrical brachial plexopathy
Heise Carlos O.,Gherpelli José Luiz D.
Arquivos de Neuro-Psiquiatria , 2006,
Abstract: We did a case-control study to verify if the birthweight, forceps delivery or perinatal asphyxia have any significant effect on the prognosis of obstetrical brachial plexopathy. Group A was composed of 25 infants who completely recovered at the age of 6 months. Group B was composed of 21 infants who were still not able to remove a blindfold from the face with the affected limb in the sitting position at the age of 12 months. There was no statistical difference of the median birthweight or median first minute Apgar score between the groups. There was also no relation between birthweight higher than 4000g, first minute Apgar score lower than 6 or forceps delivery with a poor prognosis.
Dopa-sensitive progressive dystonia of childhood with diurnal fluctuations of symptoms: a case report
Gherpelli, José Luiz Dias;Nagae, Lídia Mayumi;Diament, Aron;
Arquivos de Neuro-Psiquiatria , 1995, DOI: 10.1590/S0004-282X1995000200022
Abstract: progressive dystonia with diurnal fluctuations sensitive to levodopa, also known as segawa's disease, is a rare form of autosomal dominant extrapyramidal disease in the pediatric age group. the dystonic and parkinson-like symptoms are the main clinical features of the disease and, characteristically but not in all cases, show a diurnal variation. they are absent or present to a lesser extent in the morning, worsening during the day. treatment with small doses of levodopa results in remission or marked improvement of the symptomatology. we present the case of a 11 years old female patient that developed a dystonic posture in her feet that led her to a tip-toe walking pattern, since the age of 2. diurnal fluctuations of the symptomatology were noticed by her mother. at 7 years of age she developed a left deviation of the head and an abnormal flexor posture of the left arm. in the next years the symptoms progressed and the fluctuations became less evident. at the age of 10, they were present soon after she woke up in the morning. the neurological examination disclosed a dystonic posturing of the head and left arm, a generalized rigidity of the extremities and a palpebral tremor. laboratory examinations, including copper and ceruloplasmin, and neuro-imaging studies were negative. she was started on levodopa 150 mg/day with prompt disappearance of the symptomatology. after one-year follow-up she is symptom-free with only 100 mg/day of levodopa. no adverse effect was observed so far.
Importancia da avalia??o dos movimentos generalizados espontaneos no prognóstico neurológico de recém-nascidos pré-termo
Garcia, Juliana M.;Gherpelli, José Luiz D.;Leone, Cléa R.;
Jornal de Pediatria , 2004, DOI: 10.2223/1203
Abstract: objective: to study the relationship among the quality, type, and trajectory of general movements in preterm infants and neonatal cranial ultrasonography findings and neurological outcome. method: forty preterm newborn infants, with gestational ages under 35 weeks, had their general movements recorded through video-tape during the preterm, term (37th - 42nd postconceptional weeks of age) and post-term (49th - 56th postconceptional weeks of age) periods, and were prospectively followed up to one-year conceptional age. results: our results showed that the quality of general movements, particularly in the post-term period (p = 0.009), were related with the presence of severe cerebral lesions in the neonatal cranial ultrasonography and the neurological outcome. while the presence of severe ultrasonography lesions was associated with an adverse neurological outcome (p = 0.01), the finding of normal general movements patterns was associated with a normal neurological outcome, with negative predictive values of 100%, for the preterm, and 80%, for both term and post-term periods. conclusions: when concurrently used, these evaluation methods may increase the specificity and sensitivity in detecting the group of preterm infants at high-risk for neurological disturbances in long-term follow-up.
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